2YZ1
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2JY9
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![BU of 2jy9 by Molmil](/molmil-images/mine/2jy9) | NMR structure of putative tRNA hydrolase domain from Salmonella typhimurium. NorthEast Structural Genomics Consortium target StR220 | 分子名称: | Putative tRNA hydrolase domain | 著者 | Singarapu, K.K, Wu, Y, Sukumaran, D, Eletsky, A, Zeri, A, Wang, D, Janjua, H, Owens, L, Xiao, R, Liu, J, Baran, M.C, Swapna, G.V.T, Acton, T.B, Rost, B, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2007-12-07 | 公開日 | 2008-01-01 | 最終更新日 | 2024-05-08 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structure of putative tRNA hydrolase domain from Salmonella typhimurium. To be Published
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6ORI
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![BU of 6ori by Molmil](/molmil-images/mine/6ori) | Enterococcal surface protein, partial N-terminal region | 分子名称: | CALCIUM ION, EF0056 | 著者 | Spiegelman, L, Zhang, L, Tezcan, A, Ghosh, P. | 登録日 | 2019-04-30 | 公開日 | 2020-05-13 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Enterococcal surface protein, partial N-terminal region (CASP target) To Be Published
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2K28
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![BU of 2k28 by Molmil](/molmil-images/mine/2k28) | Solution NMR structure of the chromo domain of the chromobox protein homolog 4 | 分子名称: | E3 SUMO-protein ligase CBX4 | 著者 | Kaustov, L, Lemak, A, Quyang, H, Fares, C, Gutmanas, A, Ravichandran, M, Loppnau, P, Bountra, C, Weigelt, J, Edwards, A.M, Min, J, Arrowsmith, C.H, Structural Genomics Consortium (SGC) | 登録日 | 2008-03-27 | 公開日 | 2008-04-08 | 最終更新日 | 2024-05-08 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR structure of the chromo domain of the chromobox protein homolog 4. To be Published
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2YMW
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6OCK
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![BU of 6ock by Molmil](/molmil-images/mine/6ock) | Crystal Structure of Leporine Serum Albumin in Complex with Ketoprofen | 分子名称: | (20S)-2,5,8,11,14,17-HEXAMETHYL-3,6,9,12,15,18-HEXAOXAHENICOSANE-1,20-DIOL, (2R)-2-{[(2R)-2-{[(2R)-2-hydroxypropyl]oxy}propyl]oxy}propan-1-ol, (2S)-2-[3-(benzenecarbonyl)phenyl]propanoic acid, ... | 著者 | Zielinski, K, Sekula, B, Bujacz, A, Bujacz, G. | 登録日 | 2019-03-24 | 公開日 | 2020-01-15 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural investigations of stereoselective profen binding by equine and leporine serum albumins. Chirality, 32, 2020
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5EIW
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![BU of 5eiw by Molmil](/molmil-images/mine/5eiw) | DENGUE 3 NS5 METHYLTRANSFERASE BOUND TO S-ADENOSYL METHIONINE AND FRAGMENT NB3C2 | 分子名称: | 4-(TRIFLUOROMETHYL)BENZENE-1,2-DIAMINE, NS5 methyltransferase, S-ADENOSYLMETHIONINE | 著者 | Barral, K, Bricogne, G, Sharff, A. | 登録日 | 2015-10-30 | 公開日 | 2016-10-26 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.611 Å) | 主引用文献 | Discovery of novel dengue virus NS5 methyltransferase non-nucleoside inhibitors by fragment-based drug design. Eur.J.Med.Chem., 125, 2016
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5AYG
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![BU of 5ayg by Molmil](/molmil-images/mine/5ayg) | Crystal Structure of the Human ROR gamma Ligand Binding Domain With 3g | 分子名称: | 3-[5-(2-cyclohexylethyl)-4-ethyl-1,2,4-triazol-3-yl]-N-naphthalen-1-yl-propanamide, Nuclear receptor ROR-gamma | 著者 | Noguchi, M, Doi, S, Nomura, A, Kikuwaka, M, Murase, K, Hirata, K, Kamada, M, Adachi, T. | 登録日 | 2015-08-20 | 公開日 | 2016-03-02 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | SAR Exploration Guided by LE and Fsp(3): Discovery of a Selective and Orally Efficacious ROR gamma Inhibitor Acs Med.Chem.Lett., 7, 2016
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6OUM
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6OUX
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![BU of 6oux by Molmil](/molmil-images/mine/6oux) | Structure of SMUL_1544, a decarboxylase from Sulfurospirillum multivorans | 分子名称: | Threonine phosphate decarboxylase-like enzyme | 著者 | Wetterhorn, K.M, Rayment, I, Vecellio, A, Seeger, M, Keller, S, Schubert, T. | 登録日 | 2019-05-05 | 公開日 | 2019-06-05 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Structural and functional analysis of an l-serine O-phosphate decarboxylase involved in norcobamide biosynthesis. Febs Lett., 593, 2019
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6OVO
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![BU of 6ovo by Molmil](/molmil-images/mine/6ovo) | Crystal structure of the unliganded PG10 TCR | 分子名称: | 1,2-ETHANEDIOL, Alpha Chain T-Cell Receptor PG10, Beta Chain T-Cell Receptor PG10, ... | 著者 | Shahine, A, Rossjohn, J. | 登録日 | 2019-05-08 | 公開日 | 2019-11-20 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | A TCR beta-Chain Motif Biases toward Recognition of Human CD1 Proteins. J Immunol., 203, 2019
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6E64
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6OCT
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![BU of 6oct by Molmil](/molmil-images/mine/6oct) | Crystal structure of human KCTD16 T1 domain | 分子名称: | BTB/POZ domain-containing protein KCTD16 | 著者 | Zuo, H, Glaaser, I, Zhao, Y, Kurinov, I, Mosyak, L, Wang, H, Liu, J, Park, J, Frangaj, A, Sturchler, E, Zhou, M, McDonald, P, Geng, Y, Slesinger, P.A, Fan, Q.R. | 登録日 | 2019-03-25 | 公開日 | 2019-04-10 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural basis for auxiliary subunit KCTD16 regulation of the GABABreceptor. Proc.Natl.Acad.Sci.USA, 116, 2019
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6OK3
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![BU of 6ok3 by Molmil](/molmil-images/mine/6ok3) | Crystal structure of Sel1 repeat protein from Oxalobacter formigenes | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, SULFATE ION, ... | 著者 | Chang, C, Tesar, C, Endres, M, Babnigg, G, Hassan, H, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2019-04-12 | 公開日 | 2020-04-15 | 実験手法 | X-RAY DIFFRACTION (2.353 Å) | 主引用文献 | Crystal structure of Sel1 repeat protein from Oxalobacter formigenes To Be Published
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2DRK
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2IWI
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![BU of 2iwi by Molmil](/molmil-images/mine/2iwi) | CRYSTAL STRUCTURE OF THE HUMAN PIM2 IN COMPLEX WITH A RUTHENIUM ORGANOMETALLIC LIGAND RU1 | 分子名称: | RUTHENIUM-PYRIDOCARBAZOLE-1, SERINE/THREONINE-PROTEIN KINASE PIM-2 | 著者 | Russo, S, Debreczeni, J.E, Amos, A, Bullock, A.N, Fedorov, O, Niesen, F, Sobott, F, Turnbull, A, Pike, A.C.W, Ugochukwu, E, Papagrigoriou, E, Bunkoczi, G, Gorrec, F, Edwards, A, Arrowsmith, C, Weigelt, J, Sundstrom, M, von Delft, F, Knapp, S. | 登録日 | 2006-06-30 | 公開日 | 2006-08-02 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal structure of the PIM2 kinase in complex with an organoruthenium inhibitor. PLoS ONE, 4, 2009
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6OL2
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![BU of 6ol2 by Molmil](/molmil-images/mine/6ol2) | Crystallography of novel WNK1 and WNK3 inhibitors discovered from high-throughput-screening | 分子名称: | ACETATE ION, GLYCEROL, N-[2-(5,8-dimethoxy-2-oxo-1,2-dihydroquinolin-3-yl)ethyl]-2-iodobenzamide, ... | 著者 | Chlebowicz, J, Akella, R, Sekulski, K, Humphreys, J.M, Durbacz, M.Z, He, H, Rodan, A, Posner, B, Goldsmith, E.J. | 登録日 | 2019-04-15 | 公開日 | 2020-04-15 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystallography of novel WNK1 and WNK3 inhibitors discovered from high throughput screening To Be Published
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6OUD
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5SHP
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![BU of 5shp by Molmil](/molmil-images/mine/5shp) | Crystal Structure of human phosphodiesterase 10 in complex with 2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfanyl]-3H-imidazo[4,5-h]quinoline | 分子名称: | 2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfanyl}-1H-imidazo[4,5-h]quinoline, MAGNESIUM ION, ZINC ION, ... | 著者 | Joseph, C, Benz, J, Flohr, A, Krasso, A, Rudolph, M.G. | 登録日 | 2022-02-01 | 公開日 | 2022-10-12 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | Crystal Structure of a human phosphodiesterase 10 complex To be published
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6OUF
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6OWY
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![BU of 6owy by Molmil](/molmil-images/mine/6owy) | Spy H96L:Im7 K20pI-Phe complex; multiple anomalous datasets contained herein for element identification | 分子名称: | CHLORIDE ION, IMIDAZOLE, IODIDE ION, ... | 著者 | Rocchio, S, Duman, R, El Omari, K, Mykhaylyk, V, Yan, Z, Wagner, A, Bardwell, J.C.A, Horowitz, S. | 登録日 | 2019-05-12 | 公開日 | 2019-05-29 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Identifying dynamic, partially occupied residues using anomalous scattering. Acta Crystallogr D Struct Biol, 75, 2019
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6OXZ
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![BU of 6oxz by Molmil](/molmil-images/mine/6oxz) | HIV-1 Protease NL4-3 WT in Complex with LR2-20 | 分子名称: | (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-4-{({4-[(1R)-1,2-dihydroxyethyl]phenyl}sulfonyl)[(2S)-2-methylbutyl]amino}-3-hydroxy-1-phenylbutan-2-yl]carbamate, Protease NL4-3, SULFATE ION | 著者 | Lockbaum, G.J, Rusere, L.N, Lee, S.K, Henes, M, Kosovrasti, K, Spielvogel, E, Nalivaika, E.A, Swanstrom, R, KurtYilmaz, N, Schiffer, C.A, Ali, A. | 登録日 | 2019-05-14 | 公開日 | 2019-08-21 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.961 Å) | 主引用文献 | HIV-1 Protease Inhibitors Incorporating Stereochemically Defined P2' Ligands To Optimize Hydrogen Bonding in the Substrate Envelope. J.Med.Chem., 62, 2019
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6ORA
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![BU of 6ora by Molmil](/molmil-images/mine/6ora) | An Unexpected Intermediate in the Reaction Catalyzed by Quinolinate Synthase | 分子名称: | (2~{Z})-2-(1-oxidanyl-3-oxidanylidene-propyl)iminobutanedioic acid, 2-hydroxy-N-[(1S)-1-hydroxy-3-oxopropyl]-L-aspartic acid, ACETATE ION, ... | 著者 | Esakova, O.A, Grove, T.L, Silakov, A, Yennawar, N.H, Booker, S.J. | 登録日 | 2019-04-29 | 公開日 | 2019-08-21 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | An Unexpected Species Determined by X-ray Crystallography that May Represent an Intermediate in the Reaction Catalyzed by Quinolinate Synthase. J.Am.Chem.Soc., 141, 2019
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4HU1
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![BU of 4hu1 by Molmil](/molmil-images/mine/4hu1) | Crystal structure of human carbonic anhydrase isozyme XIII with the inhibitor. | 分子名称: | 1,2-ETHANEDIOL, 2,3,5,6-tetrafluoro-4-[(2-hydroxyethyl)sulfonyl]benzenesulfonamide, Carbonic anhydrase 13, ... | 著者 | Smirnov, A, Manakova, E, Grazulis, S. | 登録日 | 2012-11-02 | 公開日 | 2013-04-10 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | 4-Substituted-2,3,5,6-tetrafluorobenzenesulfonamides as inhibitors of carbonic anhydrases I, II, VII, XII, and XIII. Bioorg.Med.Chem., 21, 2013
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6O4X
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![BU of 6o4x by Molmil](/molmil-images/mine/6o4x) | Binary complex of native hAChE with 9-aminoacridine | 分子名称: | 9-AMINOACRIDINE, Acetylcholinesterase, GLYCEROL, ... | 著者 | Gerlits, O, Kovalevsky, A, Radic, Z. | 登録日 | 2019-03-01 | 公開日 | 2019-06-19 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | A new crystal form of human acetylcholinesterase for exploratory room-temperature crystallography studies. Chem.Biol.Interact., 309, 2019
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