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2YZ1

Crystal structure of the ligand-binding domain of murine SHPS-1/SIRP alpha

Summary for 2YZ1
Entry DOI10.2210/pdb2yz1/pdb
DescriptorTyrosine-protein phosphatase non-receptor type substrate 1 (2 entities in total)
Functional Keywordsbeta-sandwich, structural genomics, nppsfa, national project on protein structural and functional analyses, alternative splicing, glycoprotein, immunoglobulin domain, membrane, phosphorylation, polymorphism, sh3-binding, transmembrane, immune system
Biological sourceMus musculus (house mouse)
Cellular locationMembrane; Single-pass type I membrane protein: P97797
Total number of polymer chains2
Total formula weight26027.23
Authors
Nakaishi, A. (deposition date: 2007-05-02, release date: 2007-12-11, Last modification date: 2011-07-13)
Primary citationNakaishi, A.,Hirose, M.,Yoshimura, M.,Oneyama, C.,Saito, K.,Kuki, N.,Matsuda, M.,Honma, N.,Ohnishi, H.,Matozaki, T.,Okada, M.,Nakagawa, A.
Structural insight into the specific interaction between murine SHPS-1/SIRP alpha and its ligand CD47
J.Mol.Biol., 375:650-660, 2008
Cited by
PubMed: 18045614
DOI: 10.1016/j.jmb.2007.10.085
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.4 Å)
Structure validation

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