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2YZ1

Crystal structure of the ligand-binding domain of murine SHPS-1/SIRP alpha

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Tyrosine-protein phosphatase non-receptor type substrate 1polymer12013013.62UniProt (P97797)
Pfam (PF07686)
Mus musculus (house mouse)SHP substrate 1, SHPS-1, Inhibitory receptor SHPS-1, Signal- regulatory protein alpha-1, Sirp-alpha-1, mSIRP-alpha1, MyD-1 antigen, Brain Ig-like molecule with tyrosine-based activation motifs, Bit, p84, CD172a antigen,SRC homology 2 domain-containing protein tyrosine phosphatase substrate 1
2C, D
(A, B)
waterwater18.0303Chemie (HOH)
Sequence modifications
A, B: 6 - 120 (UniProt: P97797)
PDBExternal DatabaseDetails
Gly 1-expression tag
Pro 2-expression tag
Leu 3-expression tag
Gly 4-expression tag
Ser 5-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight26027.2
All*Total formula weight26027.2
*Water molecules are not included.

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PDB entries from 2025-12-17

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