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6J0M
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BU of 6j0m by Molmil
Cryo-EM Structure of an Extracellular Contractile Injection System, PVC baseplate in extended state (reconstructed with C3 symmetry)
分子名称: Pvc8
著者Jiang, F, Li, N, Wang, X, Cheng, J, Huang, Y, Yang, Y, Yang, J, Cai, B, Wang, Y, Jin, Q, Gao, N.
登録日2018-12-24
公開日2019-04-10
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Cryo-EM Structure and Assembly of an Extracellular Contractile Injection System.
Cell, 177, 2019
6J0N
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BU of 6j0n by Molmil
Cryo-EM Structure of an Extracellular Contractile Injection System, baseplate in extended state, refined in C6 symmetry
分子名称: Pvc1, Pvc11, Pvc12, ...
著者Jiang, F, Li, N, Wang, X, Cheng, J, Huang, Y, Yang, Y, Yang, J, Cai, B, Wang, Y, Jin, Q, Gao, N.
登録日2018-12-25
公開日2019-04-10
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM Structure and Assembly of an Extracellular Contractile Injection System.
Cell, 177, 2019
3KAY
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BU of 3kay by Molmil
Crystal structure of abscisic acid receptor PYL1
分子名称: Putative uncharacterized protein At5g46790
著者Zhou, X.E, Melcher, K, Ng, L.-M, Soon, F.-F, Xu, Y, Suino-Powell, K.M, Kovach, A, Li, J, Xu, H.E.
登録日2009-10-19
公開日2009-12-08
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Agate-latch-lock mechanism for hormone signalling by abscisic acid receptors
Nature, 462, 2009
3KB0
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BU of 3kb0 by Molmil
Crystal structure of abscisic acid-bound PYL2
分子名称: (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid, Putative uncharacterized protein At2g26040
著者Zhou, X.E, Melcher, K, Ng, L.-M, Soon, F.-F, Xu, Y, Suino-Powell, K.M, Kovach, A, Li, J, Xu, H.E.
登録日2009-10-19
公開日2009-12-08
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Agate-latch-lock mechanism for hormone signalling by abscisic acid receptors
Nature, 462, 2009
3KAZ
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BU of 3kaz by Molmil
Crystal structure of abscisic acid receptor PYL2
分子名称: 1,3-BUTANEDIOL, Putative uncharacterized protein At2g26040
著者Zhou, X.E, Melcher, K, Ng, L.-M, Soon, F.-F, Xu, Y, Suino-Powell, K.M, Kovach, A, Li, J, Xu, H.E.
登録日2009-10-19
公開日2009-12-08
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Agate-latch-lock mechanism for hormone signalling by abscisic acid receptors
Nature, 462, 2009
8GXP
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BU of 8gxp by Molmil
Complex structure of RORgama with betulinic acid
分子名称: Betulinic acid, Nuclear receptor ROR-gamma
著者Zhang, X.L, Xu, C, Bai, F.
登録日2022-09-20
公開日2023-06-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Discovery, structural optimization, and anti-tumor bioactivity evaluations of betulinic acid derivatives as a new type of ROR gamma antagonists.
Eur.J.Med.Chem., 257, 2023
6MNL
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BU of 6mnl by Molmil
NMR solution structures of second bromodomain of BRD4 with FOXO3a peptide
分子名称: Bromodomain-containing protein 4, FOXO3a peptide
著者Zeng, L, Zhou, M.-M.
登録日2018-10-02
公開日2018-10-31
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Targeting the BRD4/FOXO3a/CDK6 axis sensitizes AKT inhibition in luminal breast cancer.
Nat Commun, 9, 2018
6J0Q
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BU of 6j0q by Molmil
Crystal structure of P domain from GII.11 swine norovirus
分子名称: VP1 capsid protein
著者Chen, Y.
登録日2018-12-25
公開日2019-11-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis of host ligand specificity change of GII porcine noroviruses from their closely related GII human noroviruses.
Emerg Microbes Infect, 8, 2019
3KB3
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BU of 3kb3 by Molmil
Crystal structure of abscisic acid-bound PYL2 in complex with HAB1
分子名称: (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid, MAGNESIUM ION, Protein phosphatase 2C 16, ...
著者Zhou, X.E, Melcher, K, Soon, F.-F, Ng, L.-M, Xu, Y, Suino-Powell, K.M, Kovach, A, Li, J, Xu, H.E.
登録日2009-10-20
公開日2009-12-08
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Agate-latch-lock mechanism for hormone signalling by abscisic acid receptors
Nature, 462, 2009
4M5B
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BU of 4m5b by Molmil
Crystal Structure of an Truncated Transition Metal Transporter
分子名称: Cobalamin biosynthesis protein CbiM, HEXANE-1,6-DIOL, NICKEL (II) ION
著者Yu, Y.
登録日2013-08-08
公開日2014-03-26
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.833 Å)
主引用文献Planar substrate-binding site dictates the specificity of ECF-type nickel/cobalt transporters
Cell Res., 24, 2014
5GMS
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BU of 5gms by Molmil
Crystal structure of the mutant S202W/I203F of the esterase E40
分子名称: Esterase
著者Zhang, Y.-Z, Li, P.-Y.
登録日2016-07-15
公開日2017-07-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural and Mechanistic Insights into the Improvement of the Halotolerance of a Marine Microbial Esterase by Increasing Intra- and Interdomain Hydrophobic Interactions.
Appl. Environ. Microbiol., 83, 2017
3TH8
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BU of 3th8 by Molmil
Structure of E. coli undecaprenyl diphosphate synthase complexed with BPH-1063
分子名称: (2Z)-4-({3-[3-(hexyloxy)phenyl]propyl}amino)-2-hydroxy-4-oxobut-2-enoic acid, Undecaprenyl pyrophosphate synthase
著者Cao, R, Zhu, W, Zhang, Y, Oldfield, E.
登録日2011-08-18
公開日2012-07-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.114 Å)
主引用文献HIV-1 Integrase Inhibitor-Inspired Antibacterials Targeting Isoprenoid Biosynthesis.
ACS Med Chem Lett, 3, 2012
5GMR
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BU of 5gmr by Molmil
Crystal structure of the mutant M3+S202W/I203F of the esterase E40
分子名称: Esterase
著者Zhang, Y.-Z, Li, P.-Y.
登録日2016-07-15
公開日2017-07-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural and Mechanistic Insights into the Improvement of the Halotolerance of a Marine Microbial Esterase by Increasing Intra- and Interdomain Hydrophobic Interactions.
Appl. Environ. Microbiol., 83, 2017
6KE1
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BU of 6ke1 by Molmil
Crystal structure of TtCas1
分子名称: CRISPR-associated endonuclease Cas1 2
著者Wang, Y.L, Li, J.Z, Yang, J, Wang, J.Y.
登録日2019-07-03
公開日2019-12-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.39 Å)
主引用文献Crystal structure of Cas1 in complex with branched DNA.
Sci China Life Sci, 63, 2020
6KDV
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BU of 6kdv by Molmil
Crystal structure of TtCas1-DNA complex
分子名称: CRISPR-associated endonuclease Cas1 2, DNA (5'-D(*GP*AP*GP*TP*CP*GP*AP*TP*GP*CP*TP*GP*GP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DNA (5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*CP*CP*AP*GP*CP*AP*TP*CP*GP*AP*CP*TP*C)-3')
著者Wang, Y.L, Li, J.Z, Yang, J, Wang, J.Y.
登録日2019-07-02
公開日2019-12-18
最終更新日2020-05-06
実験手法X-RAY DIFFRACTION (3.11 Å)
主引用文献Crystal structure of Cas1 in complex with branched DNA.
Sci China Life Sci, 63, 2020
3OJI
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BU of 3oji by Molmil
X-ray crystal structure of the Py13 -pyrabactin complex
分子名称: 4-bromo-N-(pyridin-2-ylmethyl)naphthalene-1-sulfonamide, Abscisic acid receptor PYL3, SULFATE ION
著者Zhang, X, Zhang, Q, Wang, G, Chen, Z.
登録日2010-08-23
公開日2011-08-10
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Complex Structures of the Abscisic Acid Receptor PYL3/RCAR13 Reveal a Unique Regulatory Mechanism
Structure, 20, 2012
6KVH
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BU of 6kvh by Molmil
The mutant crystal structure of endo-polygalacturonase (T284A) from Talaromyces leycettanus JCM 12802
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose, endo-polygalacturonase
著者Tu, T, Wang, Z, Luo, H, Yao, B.
登録日2019-09-04
公開日2020-09-09
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Structural Insights into the Mechanisms Underlying the Kinetic Stability of GH28 Endo-Polygalacturonase.
J.Agric.Food Chem., 69, 2021
5KPU
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BU of 5kpu by Molmil
Crystal structure of TEM1 beta-lactamase mutant I263L in the presence of 1.2 MPa xenon
分子名称: Beta-lactamase TEM, XENON
著者Roose, B.W, Dmochowski, I.J.
登録日2016-07-05
公開日2017-08-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献A Structural Basis for129Xe Hyper-CEST Signal in TEM-1 beta-Lactamase.
Chemphyschem, 2018
6LB0
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BU of 6lb0 by Molmil
The cryo-EM structure of HEV VLP in complex with Fab 8C11
分子名称: Protein ORF2
著者Zheng, Q, He, M, Li, S.
登録日2019-11-13
公開日2019-12-04
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Viral neutralization by antibody-imposed physical disruption.
Proc.Natl.Acad.Sci.USA, 2019
6KZ6
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BU of 6kz6 by Molmil
Crystal structure of ASFV dUTPase
分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, E165R, MAGNESIUM ION
著者Guo, Y, Chen, C, Li, G.B, Cao, L, Wang, C.W.
登録日2019-09-23
公開日2019-11-13
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.187 Å)
主引用文献Structural Insight into African Swine Fever Virus dUTPase Reveals a Novel Folding Pattern in the dUTPase Family.
J.Virol., 94, 2020
2MJV
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BU of 2mjv by Molmil
Solution structures of second bromodomain of Brd4 with di-acetylated Twist peptide
分子名称: Bromodomain-containing protein 4, Twist-related protein 1
著者Zeng, L, Zhou, M.
登録日2014-01-16
公開日2014-03-19
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Disrupting the Interaction of BRD4 with Diacetylated Twist Suppresses Tumorigenesis in Basal-like Breast Cancer.
Cancer Cell, 25, 2014
5KZP
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BU of 5kzp by Molmil
Structure of the HCV1-C1 Antibody-Antigen Complex
分子名称: ACETATE ION, C1 Epitope, CALCIUM ION, ...
著者Piepenbrink, K.H, Sundberg, E.J.
登録日2016-07-25
公開日2017-07-05
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.262 Å)
主引用文献Structure-Based Design of Hepatitis C Virus Vaccines That Elicit Neutralizing Antibody Responses to a Conserved Epitope.
J. Virol., 91, 2017
6KZI
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BU of 6kzi by Molmil
Crystal structure of Ser/Thr kinase Pim1 in complex with thioridazine derivatives
分子名称: 4-(2-chloro-10H-phenoxazin-10-yl)-N,N-diethylbutan-1-amine, Serine/threonine-protein kinase pim-1
著者Zhang, W, Wan, X, Li, W, Xie, Y, Huang, N.
登録日2019-09-24
公開日2020-03-04
最終更新日2021-03-17
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure-Based Optimization of 10-DEBC Derivatives as Potent and Selective Pim-1 Kinase Inhibitors.
J.Chem.Inf.Model., 60, 2020
8KCI
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BU of 8kci by Molmil
ATP-bound hMRP5 outward-open
分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 5, MAGNESIUM ION
著者Liu, Z.M, Huang, Y.
登録日2023-08-07
公開日2024-07-03
実験手法ELECTRON MICROSCOPY (3.94 Å)
主引用文献Inhibition and transport mechanisms of the ABC transporter hMRP5.
Nat Commun, 15, 2024
6A7W
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BU of 6a7w by Molmil
Structure of a catalytic domain of the colistin resistance enzyme
分子名称: Putative integral membrane protein, ZINC ION
著者Wang, X.D, Chai, Y, Qi, J.X, Gao, G.F.
登録日2018-07-04
公開日2018-11-07
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.988 Å)
主引用文献Structural and functional insights into MCR-2 mediated colistin resistance.
Sci China Life Sci, 61, 2018

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