7PLN
 
 | | Structure of the APCbeta domain of Plasmodium vivax perforin-like protein 1 | | 分子名称: | Sporozoite micronemal protein essential for cell traversal, putative | | 著者 | Williams, S.I, Ni, T, Yu, X, Gilbert, R.J.C. | | 登録日 | 2021-08-31 | | 公開日 | 2022-06-29 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | | 主引用文献 | Structural, Functional and Computational Studies of Membrane Recognition by Plasmodium Perforin-Like Proteins 1 and 2
J.Mol.Biol., 434, 2022
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9JHJ
 | | Cryo-EM structure of the C18:0 ceramide-bound FPR2-Gi complex | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | | 著者 | Sun, J.P, Jiang, C.T, Kong, W, Yu, X, Cai, K, Guo, L.L. | | 登録日 | 2024-09-09 | | 公開日 | 2025-03-19 | | 最終更新日 | 2025-07-02 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Metabolic signaling of ceramides through the FPR2 receptor inhibits adipocyte thermogenesis.
Science, 388, 2025
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1N03
 | | Model for Active RecA Filament | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, RecA protein | | 著者 | VanLoock, M.S, Yu, X, Yang, S, Lai, A.L, Low, C, Campbell, M.J, Egelman, E.H. | | 登録日 | 2002-10-10 | | 公開日 | 2003-02-25 | | 最終更新日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (20 Å) | | 主引用文献 | ATP-Mediated Conformational Changes in the RecA Filament
Structure, 11, 2003
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6CT0
 | | Atomic Structure of the E2 Inner Core of Human Pyruvate Dehydrogenase Complex | | 分子名称: | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial | | 著者 | Jiang, J, Baiesc, F.L, Hiromasa, Y, Yu, X, Hui, W.H, Dai, X, Roche, T.E, Zhou, Z.H. | | 登録日 | 2018-03-21 | | 公開日 | 2018-04-18 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Atomic Structure of the E2 Inner Core of Human Pyruvate Dehydrogenase Complex.
Biochemistry, 57, 2018
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5L2I
 | | The X-ray co-crystal structure of human CDK6 and Palbociclib. | | 分子名称: | 6-ACETYL-8-CYCLOPENTYL-5-METHYL-2-[(5-PIPERAZIN-1-YLPYRIDIN-2-YL)AMINO]PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE, Cyclin-dependent kinase 6 | | 著者 | Chen, P, Ferre, R.A, Deihl, W, Yu, X, He, Y.-A. | | 登録日 | 2016-08-01 | | 公開日 | 2016-08-24 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Spectrum and Degree of CDK Drug Interactions Predicts Clinical Performance.
Mol.Cancer Ther., 15, 2016
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5L2W
 | | The X-ray co-crystal structure of human CDK2/CyclinE and Dinaciclib. | | 分子名称: | 3-[({3-ethyl-5-[(2S)-2-(2-hydroxyethyl)piperidin-1-yl]pyrazolo[1,5-a]pyrimidin-7-yl}amino)methyl]-1-hydroxypyridinium, Cyclin-dependent kinase 2, G1/S-specific cyclin-E1, ... | | 著者 | Chen, P, Ferre, R.A, Deihl, W, Yu, X, He, Y.-A. | | 登録日 | 2016-08-02 | | 公開日 | 2016-08-24 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Spectrum and Degree of CDK Drug Interactions Predicts Clinical Performance.
Mol.Cancer Ther., 15, 2016
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5L2T
 | | The X-ray co-crystal structure of human CDK6 and Ribociclib. | | 分子名称: | 7-cyclopentyl-N,N-dimethyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide, Cyclin-dependent kinase 6 | | 著者 | Chen, P, Ferre, R.A, Deihl, W, Yu, X, He, Y.-A. | | 登録日 | 2016-08-02 | | 公開日 | 2016-08-24 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | | 主引用文献 | Spectrum and Degree of CDK Drug Interactions Predicts Clinical Performance.
Mol.Cancer Ther., 15, 2016
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5T7S
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5T7U
 | | Crystal structure of galectin-8N in complex with Glycerol | | 分子名称: | CHLORIDE ION, GLYCEROL, Galectin-8, ... | | 著者 | Bohari, M.H, Yu, X, Blanchard, H. | | 登録日 | 2016-09-05 | | 公開日 | 2017-01-04 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | Structure-based rationale for differential recognition of lacto- and neolacto- series glycosphingolipids by the N-terminal domain of human galectin-8.
Sci Rep, 6, 2016
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5L2S
 | | The X-ray co-crystal structure of human CDK6 and Abemaciclib. | | 分子名称: | Cyclin-dependent kinase 6, N-{5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl}-5-fluoro-4-[4-fluoro-2-methyl-1-(propan-2-yl)-1H-benzimidazol-6-yl]py rimidin-2-amine | | 著者 | Chen, P, Ferre, R.A, Deihl, W, Yu, X, He, Y.-A. | | 登録日 | 2016-08-02 | | 公開日 | 2016-08-24 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | | 主引用文献 | Spectrum and Degree of CDK Drug Interactions Predicts Clinical Performance.
Mol.Cancer Ther., 15, 2016
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5U0S
 | | Cryo-EM structure of the Mediator-RNAPII complex | | 分子名称: | Mediator complex subunit 10, Mediator complex subunit 11, Mediator complex subunit 14, ... | | 著者 | Tsai, K.-L, Yu, X, Gopalan, S, Chao, T.-C, Zhang, Y, Florens, L, Washburn, M.P, Murakami, K, Conaway, R.C, Conaway, J.W, Asturias, F. | | 登録日 | 2016-11-26 | | 公開日 | 2017-03-08 | | 最終更新日 | 2024-11-20 | | 実験手法 | ELECTRON MICROSCOPY (7.8 Å) | | 主引用文献 | Mediator structure and rearrangements required for holoenzyme formation.
Nature, 544, 2017
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5T7I
 | | Crystal structure of galectin-8N in complex with LNnT | | 分子名称: | Galectin-8, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | | 著者 | Bohari, M.H, Yu, X, Blanchard, H. | | 登録日 | 2016-09-05 | | 公開日 | 2017-01-04 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure-based rationale for differential recognition of lacto- and neolacto- series glycosphingolipids by the N-terminal domain of human galectin-8.
Sci Rep, 6, 2016
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5T7T
 | | Galectin-8 N terminal domain in complex with LNT | | 分子名称: | CHLORIDE ION, Galectin-8, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Bohari, M.H, Yu, X, Blanchard, H. | | 登録日 | 2016-09-05 | | 公開日 | 2017-01-04 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Structure-based rationale for differential recognition of lacto- and neolacto- series glycosphingolipids by the N-terminal domain of human galectin-8.
Sci Rep, 6, 2016
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5O2Y
 | | NMR structure of the calcium bound form of PulG, major pseudopilin from Klebsiella oxytoca T2SS | | 分子名称: | CALCIUM ION, General secretion pathway protein G | | 著者 | Lopez-Castilla, A, Bardiaux, B, Vitorge, B, Thomassin, J.-L, Zheng, W, Yu, X, Egelman, E.H, Nilges, M, Francetic, O, Izadi-Pruneyre, N. | | 登録日 | 2017-05-23 | | 公開日 | 2017-10-18 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the calcium-dependent type 2 secretion pseudopilus.
Nat Microbiol, 2, 2017
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2F7V
 | | Structure of acetylcitrulline deacetylase complexed with one Co | | 分子名称: | COBALT (II) ION, aectylcitrulline deacetylase | | 著者 | Shi, D, Yu, X, Roth, L, Allewell, N.M, Tuchman, M. | | 登録日 | 2005-12-01 | | 公開日 | 2006-09-26 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Structure of a novel N-acetyl-L-citrulline deacetylase from Xanthomonas campestris
Biophys.Chem., 126, 2007
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2F8H
 | | Structure of acetylcitrulline deacetylase from Xanthomonas campestris in metal-free form | | 分子名称: | aectylcitrulline deacetylase | | 著者 | Shi, D, Yu, X, Roth, L, Allewell, N.M, Tuchman, M. | | 登録日 | 2005-12-02 | | 公開日 | 2006-09-26 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Structure of a novel N-acetyl-L-citrulline deacetylase from Xanthomonas campestris
Biophys.Chem., 126, 2007
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7TAU
 | | Refined capsid structure of human adenovirus D26 at 3.4 A resolution | | 分子名称: | Fiber, Hexon protein, PIX, ... | | 著者 | Reddy, V.S, Yu, X, Barry, M.A. | | 登録日 | 2021-12-21 | | 公開日 | 2022-03-16 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (3.38 Å) | | 主引用文献 | Refined Capsid Structure of Human Adenovirus D26 at 3.4 angstrom Resolution.
Viruses, 14, 2022
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6NZU
 | | Structure of the human frataxin-bound iron-sulfur cluster assembly complex | | 分子名称: | Acyl carrier protein, Cysteine desulfurase, mitochondrial, ... | | 著者 | Fox, N.G, Yu, X, Xidong, F, Alain, M, Joseph, N, Claire, S.D, Christine, B, Han, S, Yue, W.W. | | 登録日 | 2019-02-14 | | 公開日 | 2019-05-22 | | 最終更新日 | 2025-04-02 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structure of the human frataxin-bound iron-sulfur cluster assembly complex provides insight into its activation mechanism.
Nat Commun, 10, 2019
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2R8V
 | | Native structure of N-acetylglutamate synthase from Neisseria gonorrhoeae | | 分子名称: | ACETYL COENZYME *A, Putative acetylglutamate synthase | | 著者 | Shi, D, Sagar, V, Jin, Z, Yu, X, Caldovic, L, Morizono, H, Allewell, N.M, Tuchman, M. | | 登録日 | 2007-09-11 | | 公開日 | 2008-01-15 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The crystal structure of N-acetyl-L-glutamate synthase from Neisseria gonorrhoeae provides insights into mechanisms of catalysis and regulation.
J.Biol.Chem., 283, 2008
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2R98
 | | Crystal Structure of N-acetylglutamate synthase (selenoMet substituted) from Neisseria gonorrhoeae | | 分子名称: | ACETYL COENZYME *A, Putative acetylglutamate synthase | | 著者 | Shi, D, Sagar, V, Jin, Z, Yu, X, Caldovic, L, Morizono, H, Allewell, N.M, Tuchman, M. | | 登録日 | 2007-09-12 | | 公開日 | 2008-01-15 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | The crystal structure of N-acetyl-L-glutamate synthase from Neisseria gonorrhoeae provides insights into mechanisms of catalysis and regulation.
J.Biol.Chem., 283, 2008
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4BYH
 | | Crystal structure of sialylated IgG Fc | | 分子名称: | CHLORIDE ION, IG GAMMA-1 CHAIN C REGION, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Crispin, M, Yu, X, Bowden, T.A. | | 登録日 | 2013-07-19 | | 公開日 | 2013-08-21 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal Structure of Sialylated Igg Fc: Implications for the Mechanism of Intravenous Immunoglobulin Therapy.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4QBE
 | | The second sphere residue T263 is important for function and activity of PTP1B through modulating WPD loop | | 分子名称: | Tyrosine-protein phosphatase non-receptor type 1 | | 著者 | Xiao, P, Wang, X, Wang, H.M, Fu, X.L, Cui, F.A, Yu, X, Bi, W.X. | | 登録日 | 2014-05-08 | | 公開日 | 2014-12-24 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.292 Å) | | 主引用文献 | The second-sphere residue T263 is important for the function and catalytic activity of PTP1B via interaction with the WPD-loop
Int.J.Biochem.Cell Biol., 57C, 2014
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4QBW
 | | The second sphere residue T263 is important for function and activity of PTP1B through modulating WPD loop | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1 | | 著者 | Xiao, P, Wang, X, Wang, H.M, Fu, X.L, Cui, F.A, Yu, X, Bi, W.X, Sun, J.P. | | 登録日 | 2014-05-08 | | 公開日 | 2015-02-11 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.912 Å) | | 主引用文献 | The second-sphere residue T263 is important for the function and catalytic activity of PTP1B via interaction with the WPD-loop
Int.J.Biochem.Cell Biol., 57, 2014
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9C7Y
 | | Structure Of Respiratory Syncytial Virus Polymerase in complex with JNJ-2729 | | 分子名称: | (2S)-1,1,1-trifluoro-2-[5-fluoro-6-(4-fluorophenyl)-4-(2-hydroxypropan-2-yl)pyridin-2-yl]-3-[(4M)-4-(8-methoxyquinolin-6-yl)-1H-1,2,3-triazol-1-yl]propan-2-ol, Phosphoprotein, RNA-directed RNA polymerase L | | 著者 | Yin, Y, Tran, M.T, Yu, X, Jonckers, T. | | 登録日 | 2024-06-11 | | 公開日 | 2025-01-08 | | 実験手法 | ELECTRON MICROSCOPY (3.24 Å) | | 主引用文献 | Structure-Activity Relationship of Oxacyclo- and Triazolo-Containing Respiratory Syncytial Virus Polymerase Inhibitors.
Acs Med.Chem.Lett., 15, 2024
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4P3P
 | | Structural Basis for Full-Spectrum Inhibition of Threonyl-tRNA Synthetase by Borrelidin 3 | | 分子名称: | (1R,2R)-2-[(2S,4E,6E,8R,9S,11R,13S,15S,16S)-7-cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6-dien-2-yl]cyclopentanecarboxylic acid, GLYCEROL, Threonine--tRNA ligase, ... | | 著者 | Fang, P, Yu, X, Chen, K, Chen, X, Guo, M. | | 登録日 | 2014-03-09 | | 公開日 | 2015-03-11 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural basis for full-spectrum inhibition of translational functions on a tRNA synthetase.
Nat Commun, 6, 2015
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