3CZO
 
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5UDZ
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3P12
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3P13
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7XF5
 | | Full length human CLC-2 channel in apo state | | 分子名称: | Chloride channel protein 2 | | 著者 | Wang, L. | | 登録日 | 2022-04-01 | | 公開日 | 2023-05-03 | | 最終更新日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Cryo-EM structures of ClC-2 chloride channel reveal the blocking mechanism of its specific inhibitor AK-42
Nat Commun, 14, 2023
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7XJA
 | | TMD masked refine map of human ClC-2 | | 分子名称: | Chloride channel protein 2 | | 著者 | Wang, L. | | 登録日 | 2022-04-15 | | 公開日 | 2023-05-17 | | 最終更新日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Cryo-EM structures of ClC-2 chloride channel reveal the blocking mechanism of its specific inhibitor AK-42
Nat Commun, 14, 2023
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7L70
 | | The eukaryotic translation initiation factor 2B from Homo sapiens in its apo form | | 分子名称: | Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, Translation initiation factor eIF-2B subunit delta, ... | | 著者 | Wang, L, Schoof, M, Lawrence, R, Boone, M, Frost, A, Walter, P. | | 登録日 | 2020-12-24 | | 公開日 | 2021-03-24 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | eIF2B conformation and assembly state regulates the integrated stress response.
Elife, 10, 2021
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7K5I
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2IBJ
 | | Structure of House Fly Cytochrome B5 | | 分子名称: | Cytochrome b5, MAGNESIUM ION, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Terzyan, S, Zhang, X.C, Benson, D.R, Wang, L. | | 登録日 | 2006-09-11 | | 公開日 | 2007-02-27 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Comparison of cytochromes b(5) from insects and vertebrates.
Proteins, 67, 2007
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2I89
 | | Structure of septuple mutant of Rat Outer Mitochondrial Membrane Cytochrome B5 | | 分子名称: | Cytochrome b5 type B, MAGNESIUM ION, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Terzyan, S, Zhang, X.C, Benson, D.R, Wang, L, Sun, N. | | 登録日 | 2006-09-01 | | 公開日 | 2006-10-31 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | A histidine/tryptophan pi-stacking interaction stabilizes the heme-independent folding core of microsomal apocytochrome b5 relative to that of mitochondrial apocytochrome b5.
Biochemistry, 45, 2006
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8JHU
 | | Legionella effector protein SidI | | 分子名称: | Legionella pneumophila effector protein SidI | | 著者 | Wang, L, Subramanian, A, Mukherjee, S, Walter, P. | | 登録日 | 2023-05-25 | | 公開日 | 2023-08-30 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | A Legionella toxin exhibits tRNA mimicry and glycosyl transferase activity to target the translation machinery and trigger a ribotoxic stress response.
Nat.Cell Biol., 25, 2023
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2PVX
 | | NMR and X-ray Analysis of Structural Additivity in Metal Binding Site-Swapped Hybrids of Rubredoxin | | 分子名称: | Rubredoxin, ZINC ION | | 著者 | Wang, L, LeMaster, D.M, Hernandez, G, Li, H. | | 登録日 | 2007-05-10 | | 公開日 | 2007-12-18 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.04 Å) | | 主引用文献 | NMR and X-ray analysis of structural additivity in metal binding site-swapped hybrids of rubredoxin
Bmc Struct.Biol., 7, 2007
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7ENN
 | | The structure of ALC1 bound to the nucleosome | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Chromodomain-helicase-DNA-binding protein 1-like, ... | | 著者 | Chen, Z.C, Chen, K.J, Wang, L. | | 登録日 | 2021-04-18 | | 公開日 | 2021-07-14 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structural basis of ALC1/CHD1L autoinhibition and the mechanism of activation by the nucleosome.
Nat Commun, 12, 2021
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3TKS
 | | Crystal structure of full-length human peroxiredoxin 4 in three different redox states | | 分子名称: | PEROXIDE ION, Peroxiredoxin-4 | | 著者 | Wang, X, Wang, L, Wang, X, Sun, F, Wang, C.-C. | | 登録日 | 2011-08-28 | | 公開日 | 2011-10-05 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural insights into the peroxidase activity and inactivation of human peroxiredoxin 4
Biochem.J., 2011
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3TKP
 | | Crystal structure of full-length human peroxiredoxin 4 in the reduced form | | 分子名称: | Peroxiredoxin-4 | | 著者 | Wang, X, Wang, L, Wang, X, Sun, F, Wang, C.-C. | | 登録日 | 2011-08-28 | | 公開日 | 2011-10-05 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | | 主引用文献 | Structural insights into the peroxidase activity and inactivation of human peroxiredoxin 4
Biochem.J., 2011
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7OJT
 | | Crystal structure of unliganded PatA, a membrane associated acyltransferase from Mycobacterium smegmatis | | 分子名称: | GLYCEROL, Phosphatidylinositol mannoside acyltransferase | | 著者 | Anso, I, Wang, L, Marina, A, Paez-Perez, E.D, Perrone, S, Lowary, T.L, Trastoy, B, Guerin, M.E. | | 登録日 | 2021-05-17 | | 公開日 | 2021-10-27 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3.67 Å) | | 主引用文献 | Molecular ruler mechanism and interfacial catalysis of the integral membrane acyltransferase PatA.
Sci Adv, 7, 2021
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8CTI
 | | Cryo-EM structure of human METTL1-WDR4-tRNA(Val) complex | | 分子名称: | tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4, tRNA-Val-TAC-2-1 | | 著者 | Li, J, Wang, L, Fontana, P, Hunkeler, M, Roy-Burman, S.S, Wu, H, Fischer, E.S, Gregory, R.I. | | 登録日 | 2022-05-14 | | 公開日 | 2022-12-07 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structural basis of regulated m 7 G tRNA modification by METTL1-WDR4.
Nature, 613, 2023
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8CTH
 | | Cryo-EM structure of human METTL1-WDR4-tRNA(Phe) complex | | 分子名称: | Phe-tRNA, S-ADENOSYL-L-HOMOCYSTEINE, tRNA (guanine-N(7)-)-methyltransferase, ... | | 著者 | Li, J, Wang, L, Fontana, P, Hunkeler, M, Roy-Burman, S.S, Wu, H, Fishcer, E.S, Gregory, R.I. | | 登録日 | 2022-05-14 | | 公開日 | 2022-12-07 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural basis of regulated m 7 G tRNA modification by METTL1-WDR4.
Nature, 613, 2023
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2G9G
 | | Crystal structure of His-tagged mouse PNGase C-terminal domain | | 分子名称: | GLYCEROL, SULFATE ION, peptide N-glycanase | | 著者 | Zhou, X, Zhao, G, Wang, L, Li, G, Lennarz, W.J, Schindelin, H. | | 登録日 | 2006-03-06 | | 公開日 | 2006-10-24 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural and biochemical studies of the C-terminal domain of mouse peptide-N-glycanase identify it as a mannose-binding module.
Proc.Natl.Acad.Sci.Usa, 103, 2006
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4WQN
 | | Crystal structure of N6-methyladenosine RNA reader YTHDF2 | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, YTH domain-containing family protein 2 | | 著者 | Zhu, T, Roundtree, I.A, Wang, P, Wang, X, Wang, L, Sun, C, Tian, Y, Li, J, He, C, Xu, Y. | | 登録日 | 2014-10-22 | | 公開日 | 2014-11-19 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.121 Å) | | 主引用文献 | Crystal structure of the YTH domain of YTHDF2 reveals mechanism for recognition of N6-methyladenosine.
Cell Res., 24, 2014
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8WY4
 | | GajA tetramer with ATP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Endonuclease GajA | | 著者 | Li, J, Wang, Z, Wang, L. | | 登録日 | 2023-10-30 | | 公開日 | 2024-02-28 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (2.81 Å) | | 主引用文献 | Structures and activation mechanism of the Gabija anti-phage system.
Nature, 629, 2024
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8X51
 | | Cryo-EM structure of Gabija GajA in complex with DNA(focused refinement) | | 分子名称: | CALCIUM ION, DNA (5'-D(*AP*AP*AP*AP*AP*TP*AP*AP*CP*CP*GP*GP*GP*TP*TP*AP*TP*TP*AP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*AP*AP*TP*AP*AP*CP*CP*CP*GP*GP*TP*TP*AP*TP*TP*TP*TP*T)-3'), ... | | 著者 | Li, J, Wang, Z, Wang, L. | | 登録日 | 2023-11-16 | | 公開日 | 2024-02-28 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (2.92 Å) | | 主引用文献 | Structures and activation mechanism of the Gabija anti-phage system.
Nature, 629, 2024
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8X5I
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8WY5
 | | Structure of Gabija GajA in complex with DNA | | 分子名称: | CALCIUM ION, DNA (5'-D(P*AP*AP*AP*AP*TP*AP*AP*CP*CP*GP*GP*GP*TP*TP*AP*TP*TP*AP*A)-3'), DNA (5'-D(P*TP*TP*AP*AP*TP*AP*AP*CP*CP*CP*GP*GP*TP*TP*AP*TP*TP*TP*T)-3'), ... | | 著者 | Li, J, Wang, Z, Wang, L. | | 登録日 | 2023-10-30 | | 公開日 | 2024-02-28 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | | 主引用文献 | Structures and activation mechanism of the Gabija anti-phage system.
Nature, 629, 2024
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8X5N
 | | Tetramer Gabija with ATP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Endonuclease GajA, Gabija protein GajB, ... | | 著者 | Li, J, Wang, Z, Wang, L. | | 登録日 | 2023-11-17 | | 公開日 | 2024-02-28 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structures and activation mechanism of the Gabija anti-phage system.
Nature, 629, 2024
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