6DDB
| Crystal structure of the double mutant (D52N/R367Q) of NT5C2-537X in the basal state, Northeast Structural Genomics Consortium Target | 分子名称: | Cytosolic purine 5'-nucleotidase, MANGANESE (II) ION, PHOSPHATE ION | 著者 | Forouhar, F, Dieck, C.L, Tzoneva, G, Carpenter, Z, Ambesi-Impiombato, A, Sanchez-Martin, M, Kirschner-Schwabe, R, Lew, S, Seetharaman, J, Ferrando, A.A, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2018-05-09 | 公開日 | 2018-07-04 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure and Mechanisms of NT5C2 Mutations Driving Thiopurine Resistance in Relapsed Lymphoblastic Leukemia. Cancer Cell, 34, 2018
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6DDY
| Crystal structure of the double mutant (D52N/K359Q) of NT5C2-537X in the active state, Northeast Structural Genomics Target | 分子名称: | Cytosolic purine 5'-nucleotidase, GLYCEROL, PHOSPHATE ION | 著者 | Forouhar, F, Dieck, C.L, Tzoneva, G, Carpenter, Z, Ambesi-Impiombato, A, Sanchez-Martin, M, Kirschner-Schwabe, R, Lew, S, Seetharaman, J, Ferrando, A.A, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2018-05-10 | 公開日 | 2018-07-04 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.803 Å) | 主引用文献 | Structure and Mechanisms of NT5C2 Mutations Driving Thiopurine Resistance in Relapsed Lymphoblastic Leukemia. Cancer Cell, 34, 2018
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6DDX
| Crystal structure of the double mutant (D52N/L375F) of NT5C2-537X in the active state, Northeast Structural Genomics Target | 分子名称: | Cytosolic purine 5'-nucleotidase, PHOSPHATE ION | 著者 | Forouhar, F, Dieck, C.L, Tzoneva, G, Carpenter, Z, Ambesi-Impiombato, A, Sanchez-Martin, M, Kirschner-Schwabe, R, Lew, S, Seetharaman, J, Ferrando, A.A, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2018-05-10 | 公開日 | 2018-07-04 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.901 Å) | 主引用文献 | Structure and Mechanisms of NT5C2 Mutations Driving Thiopurine Resistance in Relapsed Lymphoblastic Leukemia. Cancer Cell, 34, 2018
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6E12
| Crystal Structure of the Alr8543 protein in complex with Oleic Acid and magnesium ion from Nostoc sp. PCC 7120, Northeast Structural Genomics Consortium Target NsR141 | 分子名称: | Alr8543 protein, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Forouhar, F, Neely, H, Seetharaman, J, Xiao, R, Ciccosanti, C, Patel, D, Belote, R.L, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2018-07-09 | 公開日 | 2018-07-25 | 最終更新日 | 2019-12-04 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal Structure of the Alr8543 protein in complex with Oleic Acid and magnesium ion from Nostoc sp. PCC 7120, Northeast Structural Genomics Consortium Target NsR141 To Be Published
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6E35
| Crystal structure of human indoleamime 2,3-dioxygenase (IDO1) in complex with L-Trp and cyanide, Northeast Structural Genomics Target HR6160 | 分子名称: | 2-(1H-indol-3-yl)ethanol, CYANIDE ION, Indoleamine 2,3-dioxygenase 1, ... | 著者 | Forouhar, F, Lewis-Ballester, A, Lew, S, Karkashon, S, Seetharaman, J, Lu, C, Hussain, M, Yeh, S.-R, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2018-07-13 | 公開日 | 2018-07-25 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.411 Å) | 主引用文献 | Crystal structure of human indoleamime 2,3-dioxygenase (IDO1) in complex with L-Trp and cyanide, Northeast Structural Genomics Target HR6160 To Be Published
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1OPS
| ICE-BINDING SURFACE ON A TYPE III ANTIFREEZE PROTEIN FROM OCEAN POUT | 分子名称: | TYPE III ANTIFREEZE PROTEIN | 著者 | Yang, D.S.C, Hon, W.-C, Bubanko, S, Xue, Y, Seetharaman, J, Hew, C.L, Sicheri, F. | 登録日 | 1997-11-17 | 公開日 | 1998-05-20 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Identification of the ice-binding surface on a type III antifreeze protein with a "flatness function" algorithm. Biophys.J., 74, 1998
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3KAV
| Crystal Structure of THE MUTANT (L80M) PA2107 PROTEIN from Pseudomonas aeruginosa, Northeast Structural Genomics Consortium Target PaR198 | 分子名称: | uncharacterized protein PA2107 | 著者 | Forouhar, F, Neely, H, Seetharaman, J, Sahdev, S, Xiao, R, Ciccosanti, C, Foote, E.L, Zhao, L, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2009-10-19 | 公開日 | 2009-10-27 | 最終更新日 | 2021-10-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Northeast Structural Genomics Consortium Target PaR198 To be Published
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4RZP
| Crystal Structure of Engineered Protein. Northeast Structural Genomics Consortium (NESG) Target OR366. | 分子名称: | Engineered Protein OR366 | 著者 | Vorobiev, S, Parmeggiani, F, Dimaio, F, Seetharaman, J, Sahdev, S, Xiao, R, Kogan, S, Everett, J.K, Acton, T.B, Baker, D, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2014-12-23 | 公開日 | 2015-01-07 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.804 Å) | 主引用文献 | Crystal Structure of Engineered Protein OR366 To be Published
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2QAI
| Crystal structure of the V-type ATP synthase subunit F from Pyrococcus furiosus. NESG target PfR7. | 分子名称: | V-type ATP synthase subunit F | 著者 | Vorobiev, S.M, Su, M, Seetharaman, J, Ma, L.-C, Shih, L, Fang, Y, Xiao, R, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2007-06-15 | 公開日 | 2007-06-26 | 最終更新日 | 2018-01-24 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of the V-type ATP synthase subunit F from Pyrococcus furiosus. To be Published
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4RMM
| Crystal Structure of the Q7NVP2_CHRVO protein from Chromobacterium violaceum. Northeast Structural Genomics Consortium Target CvR191 | 分子名称: | Putative uncharacterized protein | 著者 | Vorobiev, S, Su, M, Seetharaman, J, Mao, L, Xiao, R, Ciccosanti, C, Foote, E.L, Wang, D, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2014-10-21 | 公開日 | 2014-11-05 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal Structure of the Q7NVP2_CHRVO protein from Chromobacterium violaceum. To be Published
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2QS9
| Crystal structure of the human retinoblastoma-binding protein 9 (RBBP-9). NESG target HR2978 | 分子名称: | Retinoblastoma-binding protein 9 | 著者 | Vorobiev, S.M, Su, M, Seetharaman, J, Kuzin, A, Chen, C.X, Cunningham, K, Owens, L, Maglaqui, M, Xiao, R, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2007-07-30 | 公開日 | 2007-08-14 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Crystal structure of human retinoblastoma binding protein 9. Proteins, 74, 2008
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4RV1
| Crystal Structure of Engineered Protein. Northeast Structural Genomics Consortium (NESG) Target OR497. | 分子名称: | ACETATE ION, Engineered Protein OR497 | 著者 | Vorobiev, S, Parmeggiani, F, Seetharaman, J, Xiao, R, Everett, J.K, Acton, T.B, Baker, D, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2014-11-24 | 公開日 | 2014-12-10 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.573 Å) | 主引用文献 | Crystal Structure of Engineered Protein OR497. To be Published
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3KKZ
| Crystal structure of the Q5LES9_BACFN protein from Bacteroides fragilis. Northeast Structural Genomics Consortium Target BfR250. | 分子名称: | S-ADENOSYLMETHIONINE, uncharacterized protein Q5LES9 | 著者 | Vorobiev, S, Neely, H, Seetharaman, J, Wang, D, Ciccosanti, C, Foote, E.L, Sahdev, S, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2009-11-06 | 公開日 | 2009-11-24 | 最終更新日 | 2017-10-25 | 実験手法 | X-RAY DIFFRACTION (1.677 Å) | 主引用文献 | Crystal structure of the Q5LES9_BACFN protein from Bacteroides fragilis. To be Published
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3KOJ
| Crystal structure of the SSB domain of Q5N255_SYNP6 protein from Synechococcus sp. Northeast Structural Genomics Consortium Target SnR59a. | 分子名称: | uncharacterized protein ycf41 | 著者 | Vorobiev, S, Su, M, Seetharaman, J, Wang, H, Foote, L.E, Ciccosanti, C, Janjua, H, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2009-11-13 | 公開日 | 2009-11-24 | 最終更新日 | 2021-10-13 | 実験手法 | X-RAY DIFFRACTION (1.895 Å) | 主引用文献 | Crystal structure of the SSB domain of Q5N255_SYNP6 protein from Synechococcus sp. To be Published
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4RL6
| Crystal Structure of the Q04L03_STRP2 protein from Streptococcus pneumoniae. Northeast Structural Genomics Consortium Target SpR105 | 分子名称: | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Saccharopine dehydrogenase | 著者 | Vorobiev, S, Neely, H.M, Odukwe, C.D, Seetharaman, J, Mao, L, Xiao, R, Kohan, E, Wang, D, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2014-10-15 | 公開日 | 2014-11-05 | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | 主引用文献 | Crystal Structure of the Q04L03_STRP2 protein from Streptococcus pneumoniae. To be Published
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2QZU
| Crystal structure of the putative sulfatase yidJ from Bacteroides fragilis. Northeast Structural Genomics Consortium target BfR123 | 分子名称: | Putative sulfatase yidJ | 著者 | Vorobiev, S.M, Abashidze, M, Seetharaman, J, Wang, D, Cunningham, K, Maglaqui, M, Owens, L, Xiao, R, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2007-08-17 | 公開日 | 2007-09-04 | 最終更新日 | 2017-10-25 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | X-ray crystal structure of the putative sulfatase yidJ from Bacteroides fragilis. To be Published
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2R6Z
| Crystal structure of the SAM-dependent methyltransferase NGO1261 from Neisseria gonorrhoeae, Northeast Structural Genomics Consortium Target NgR48 | 分子名称: | UPF0341 protein in rsp 3' region | 著者 | Forouhar, F, Abashidze, M, Seetharaman, J, Mao, L, Nwosu, C, Fang, Y, Xiao, R, Baran, M.C, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2007-09-06 | 公開日 | 2007-09-25 | 最終更新日 | 2017-10-25 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of the SAM-dependent methyltransferase NGO1261 from Neisseria gonorrhoeae. To be Published
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3KVP
| Crystal Structure of Uncharacterized protein ymzC Precursor from Bacillus subtilis, Northeast Structural Genomics Consortium Target SR378A | 分子名称: | ACETIC ACID, Uncharacterized protein ymzC | 著者 | Kuzin, A.P, Chen, Y, Seetharaman, J, Afonine, P, Fang, F, Xiao, R, Cunningham, K, Ma, L, Chen, C.X, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2009-11-30 | 公開日 | 2010-02-02 | 最終更新日 | 2019-07-17 | 実験手法 | X-RAY DIFFRACTION (2.404 Å) | 主引用文献 | Northeast Structural Genomics Consortium Target SR378A To be Published
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3LMA
| Crystal structure of the stage V sporulation protein AD (SpoVAD) from Bacillus licheniformis. Northeast Structural Genomics Consortium Target BiR6. | 分子名称: | Stage V sporulation protein AD (SpoVAD) | 著者 | Vorobiev, S, Ashok, S, Seetharaman, J, Belote, R.L, Ciccosanti, C, Patel, D.J, Janjua, H, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2010-01-29 | 公開日 | 2010-02-09 | 最終更新日 | 2019-08-14 | 実験手法 | X-RAY DIFFRACTION (1.993 Å) | 主引用文献 | Crystal structure of the stage V sporulation protein AD (SpoVAD) from Bacillus licheniformis. To be Published
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3LRX
| Crystal Structure of the C-terminal domain (residues 78-226) of PF1911 hydrogenase from Pyrococcus furiosus, Northeast Structural Genomics Consortium Target PfR246A | 分子名称: | Putative hydrogenase | 著者 | Forouhar, F, Abashidze, M, Seetharaman, J, Mao, M, Xiao, R, Ciccosanti, C, Foote, E.L, Belote, R.L, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2010-02-11 | 公開日 | 2010-03-16 | 最終更新日 | 2019-07-17 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Northeast Structural Genomics Consortium Target PfR246A To be Published
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4F2V
| Crystal Structure of de novo designed serine hydrolase, Northeast Structural Genomics Consortium (NESG) Target OR165 | 分子名称: | DI(HYDROXYETHYL)ETHER, DODECYL-ALPHA-D-MALTOSIDE, De novo designed serine hydrolase | 著者 | Kuzin, A, Lew, S, Seetharaman, J, Maglaqui, M, Xiao, R, Kohan, E, Rajagopalan, S, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2012-05-08 | 公開日 | 2012-05-30 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.493 Å) | 主引用文献 | Design of activated serine-containing catalytic triads with atomic-level accuracy. Nat.Chem.Biol., 10, 2014
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4F6A
| High-resolution x-ray Structure of the tetramutant of BH1408 protein from Bacillus halodurans, Northeast Structural Genomics Consortium (NESG) Target BhR182 | 分子名称: | BH1408 protein, UNKNOWN LIGAND | 著者 | Kuzin, A, Neely, H, Odukwe, N, Seetharaman, J, Patel, P, Xiao, R, Kohan, E, Everett, J.K, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2012-05-14 | 公開日 | 2012-06-13 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.009 Å) | 主引用文献 | Northeast Structural Genomics Consortium Target BhR182 To be Published
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4F67
| Three dimensional structure of the double mutant of UPF0176 protein lpg2838 from Legionella pneumophila at the resolution 1.8A, Northeast Structural Genomics Consortium (NESG) Target LgR82 | 分子名称: | UPF0176 protein lpg2838 | 著者 | Kuzin, A, Neely, H, Street, L, Odukwe, N, Seetharaman, J, Mao, M, Xiao, R, Kohan, E, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2012-05-14 | 公開日 | 2012-05-30 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Three dimensional structure of the double mutant of UPF0176 protein lpg2838 from Legionella pneumophila at the resolution 1.8A, Northeast
Structural Genomics Consortium (NESG) Target LgR82 To be Published
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4FIB
| Crystal structure of the ydhK protein from Bacillus subtilis. Northeast Structural Genomics Consortium Target SR518A. | 分子名称: | Uncharacterized protein ydhK | 著者 | Vorobiev, S, Abashidze, M, Seetharaman, J, Mao, M, Xiao, R, Maglaqui, M, Owens, L.A, Cunningham, K, Zhao, L, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2012-06-08 | 公開日 | 2012-06-20 | 実験手法 | X-RAY DIFFRACTION (1.997 Å) | 主引用文献 | Crystal structure of the ydhK protein from Bacillus subtilis. To be Published
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4FLE
| Crystal structure of the esterase YqiA (YE3661) from Yersinia enterocolitica, Northeast Structural Genomics Consortium Target YeR85 | 分子名称: | esterase | 著者 | Forouhar, F, Lew, S, Seetharaman, J, Shastry, R, Kohan, E, Maglaqui, M, Mao, L, Xiao, R, Acton, T.B, Everett, J.K, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2012-06-14 | 公開日 | 2012-08-08 | 最終更新日 | 2017-10-25 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of the esterase YqiA (YE3661) from Yersinia enterocolitica, Northeast Structural Genomics Consortium Target YeR85 (CASP Target) To be Published
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