4OHF

Crystal structure of cytosolic nucleotidase II (LPG0095) in complex with GMP from Legionella pneumophila, NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET LGR1

Summary for 4OHF

• Entry DOI: 10.2210/pdb4ohf/pdb
• Related: 4G63
• Descriptor: Cytosolic IMP-GMP specific 5'-nucleotidase, GUANOSINE-5'-MONOPHOSPHATE, PHOSPHATE ION, ... (5 entities in total)
• Functional Keywords: structural genomics, psi-biology, northeast structural genomics consortium, nesg, 3-domained structure that resembles had, nucleotidase. it catalyzes the breakdown of selected nucleoside monophosphates, cytosol, hydrolase
• Biological source: Legionella pneumophila subsp. pneumophila
• Total number of polymer chains: 4
• Total formula weight: 220505.06

Authors

Srinivisan, B.,Forouhar, F.,Shukla, A.,Sampangi, C.,Kulkarni, S.,Abashidze, M.,Seetharaman, J.,Lew, S.,Mao, L.,Acton, T.B.,Xiao, R.,Everett, J.K.,Montelione, G.M.,Tong, L.,Balaram, H.,Northeast Structural Genomics Consortium (NESG) (deposition date: 2014-01-17, release date: 2014-02-26, Last modification date: 2023-09-20)

• Primary citation: Srinivasan, B.,Forouhar, F.,Shukla, A.,Sampangi, C.,Kulkarni, S.,Abashidze, M.,Seetharaman, J.,Lew, S.,Mao, L.,Acton, T.B.,Xiao, R.,Everett, J.K.,Montelione, G.T.,Tong, L.,Balaram, H.; Allosteric regulation and substrate activation in cytosolic nucleotidase II from Legionella pneumophila.; Febs J., 281:1613-1628, 2014; PubMed: 24456211; DOI: 10.1111/febs.12727

Experimental method

X-RAY DIFFRACTION (2.53 Å)