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4TQP
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Human transthyretin (TTR) complexed with (R)-3-(9H-fluoren-9-ylideneaminooxy)-2-methyl-N-(methylsulfonyl) propionamide in a dual binding mode
分子名称: (2R)-3-[(9H-fluoren-9-ylideneamino)oxy]-2-methyl-N-(methylsulfonyl)propanamide, GLYCEROL, Transthyretin
著者Ciccone, L, Nencetti, S, Rossello, A, Orlandini, E, Stura, E.A.
登録日2014-06-11
公開日2015-06-24
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献X-ray crystal structure and activity of fluorenyl-based compounds as transthyretin fibrillogenesis inhibitors.
J Enzyme Inhib Med Chem, 2015
4TQI
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BU of 4tqi by Molmil
Human transthyretin (TTR) complexed with 3-(9H-fluoren-9-ylideneaminooxy)propanoic acid in a dual binding mode
分子名称: (2S)-3-[(9H-fluoren-9-ylideneamino)oxy]-2-methylpropanoic acid, GLYCEROL, Transthyretin
著者Stura, E.A, Ciccone, L, Nencetti, S, Rossello, A, Orlandini, E.
登録日2014-06-11
公開日2015-06-24
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献X-ray crystal structure and activity of fluorenyl-based compounds as transthyretin fibrillogenesis inhibitors.
J Enzyme Inhib Med Chem, 2015
4TQ8
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Dual binding mode for 3-(9H-fluoren-9-ylideneaminooxy)propanoic acid binding to Human transthyretin (TTR)
分子名称: 1,2-ETHANEDIOL, 3-[(9H-fluoren-9-ylideneamino)oxy]propanoic acid, Transthyretin
著者Ciccone, L, Orlandini, E, Nencetti, S, Rossello, A, Stura, E.A.
登録日2014-06-10
公開日2015-06-24
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献X-ray crystal structure and activity of fluorenyl-based compounds as transthyretin fibrillogenesis inhibitors.
J Enzyme Inhib Med Chem, 2015
1GNC
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BU of 1gnc by Molmil
STRUCTURE AND DYNAMICS OF THE HUMAN GRANULOCYTE COLONY-STIMULATING FACTOR DETERMINED BY NMR SPECTROSCOPY. LOOP MOBILITY IN A FOUR-HELIX-BUNDLE PROTEIN
分子名称: GRANULOCYTE COLONY-STIMULATING FACTOR
著者Zink, T.W, Ross, A, Rudolph, R, Holak, T.A.
登録日1994-03-08
公開日1994-07-31
最終更新日2024-10-30
実験手法SOLUTION NMR
主引用文献Structure and dynamics of the human granulocyte colony-stimulating factor determined by NMR spectroscopy. Loop mobility in a four-helix-bundle protein.
Biochemistry, 33, 1994
3ZIZ
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BU of 3ziz by Molmil
Crystal structure of Podospora anserina GH5 beta-(1,4)-mannanase
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GH5 ENDO-BETA-1,4-MANNANASE, GLYCEROL
著者Couturier, M, Roussel, A, Rosengren, A, Leone, P, Stalbrand, H, Berrin, J.G.
登録日2013-01-15
公開日2013-04-17
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural and Biochemical Analyses of Glycoside Hydrolase Families 5 and 26 Beta-(1,4)-Mannanases from Podospora Anserina Reveal Differences Upon Manno-Oligosaccharides Catalysis.
J.Biol.Chem., 288, 2013
5T7L
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BU of 5t7l by Molmil
Pt(II)-mediated copper-dependent interactions between ATOX1 and MNK1
分子名称: COPPER (II) ION, Copper transport protein ATOX1, Copper-transporting ATPase 1, ...
著者Caliandro, R, Mirabelli, V, Caliandro, R, Rosato, A, Lasorsa, A, Galliani, A, Arnesano, F, Natile, G.
登録日2016-09-05
公開日2016-10-12
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.83 Å)
主引用文献Mechanistic and Structural Basis for Inhibition of Copper Trafficking by Platinum Anticancer Drugs.
J.Am.Chem.Soc., 141, 2019
3JC1
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Electron cryo-microscopy of the IST1-CHMP1B ESCRT-III copolymer
分子名称: Charged multivesicular body protein 1b, Increased Sodium Tolerance 1 (IST1)
著者McCullough, J, Clippinger, A.K, Talledge, N, Skowyra, M.L, Saunders, M.G, Naismith, T.V, Colf, L.A, Afonine, P, Arthur, C, Sundquist, W.I, Hanson, P.I, Frost, A.
登録日2015-11-09
公開日2015-12-16
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structure and membrane remodeling activity of ESCRT-III helical polymers.
Science, 350, 2015
4TQH
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Human transthyretin (TTR) complexed with 3-(9H-fluoren-9-ylideneaminooxy)ethanoic acid
分子名称: 1,2-ETHANEDIOL, Transthyretin, [(9H-fluoren-9-ylideneamino)oxy]acetic acid
著者Ciccone, L, Nencetti, S, Rossello, A, Orlandini, E, Stura, E.A.
登録日2014-06-11
公開日2015-06-24
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.511 Å)
主引用文献X-ray crystal structure and activity of fluorenyl-based compounds as transthyretin fibrillogenesis inhibitors.
J Enzyme Inhib Med Chem, 2015
1W6H
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BU of 1w6h by Molmil
Novel plasmepsin II-inhibitor complex
分子名称: N-((3S,4S)-5-[(4-BROMOBENZYL)OXY]-3-HYDROXY-4-{[N-(PYRIDIN-2-YLCARBONYL)-L-VALYL]AMINO}PENTANOYL)-L-ALANYL-L-LEUCINAMIDE, PLASMEPSIN 2
著者Lindberg, J, Johansson, P.-O, Rosenquist, A, Kvarnstroem, I, Vrang, L, Samuelsson, B, Unge, T.
登録日2004-08-18
公開日2006-07-05
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Structural Study of a Novel Inhibitor with Bulky P1 Side Chain in Complex with Plasmepsin II -Implications for Drug Design
To be Published
1K3H
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BU of 1k3h by Molmil
NMR Solution Structure of Oxidized Cytochrome c-553 from Bacillus pasteurii
分子名称: HEME C, cytochrome c-553
著者Banci, L, Bertini, I, Ciurli, S, Dikiy, A, Dittmer, J, Rosato, A, Sciara, G, Thompsett, A.R.
登録日2001-10-03
公開日2001-10-31
最終更新日2024-11-13
実験手法SOLUTION NMR
主引用文献NMR solution structure, backbone mobility, and homology modeling of c-type cytochromes from gram-positive bacteria.
Chembiochem, 3, 2002
1K3G
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BU of 1k3g by Molmil
NMR Solution Structure of Oxidized Cytochrome c-553 from Bacillus pasteurii
分子名称: HEME C, cytochrome c-553
著者Banci, L, Bertini, I, Ciurli, S, Dikiy, A, Dittmer, J, Rosato, A, Sciara, G, Thompsett, A.R.
登録日2001-10-03
公開日2001-10-31
最終更新日2024-10-30
実験手法SOLUTION NMR
主引用文献NMR solution structure, backbone mobility, and homology modeling of c-type cytochromes from gram-positive bacteria.
Chembiochem, 3, 2002
1Y3K
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BU of 1y3k by Molmil
Solution structure of the apo form of the fifth domain of Menkes protein
分子名称: Copper-transporting ATPase 1
著者Banci, L, Chasapis, C.T, Ciofi-Baffoni, S, Hadjiliadis, N, Rosato, A, Structural Proteomics in Europe (SPINE)
登録日2004-11-25
公開日2005-03-08
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献An NMR study of the interaction between the human copper(I) chaperone and the second and fifth metal-binding domains of the Menkes protein
Febs J., 272, 2005
1Y3J
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BU of 1y3j by Molmil
Solution structure of the copper(I) form of the fifth domain of Menkes protein
分子名称: COPPER (II) ION, Copper-transporting ATPase 1
著者Banci, L, Chasapis, C.T, Ciofi-Baffoni, S, Hadjiliadis, N, Rosato, A, Structural Proteomics in Europe (SPINE)
登録日2004-11-25
公開日2005-03-08
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献An NMR study of the interaction between the human copper(I) chaperone and the second and fifth metal-binding domains of the Menkes protein
Febs J., 272, 2005
1OLL
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BU of 1oll by Molmil
Extracellular region of the human receptor NKp46
分子名称: 1,2-ETHANEDIOL, NK RECEPTOR
著者Ponassi, M, Cantoni, C, Biassoni, R, Conte, R, Spallarossa, A, Pesce, A, Moretta, A, Moretta, L, Bolognesi, M, Bordo, D.
登録日2003-08-07
公開日2003-09-04
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Structure of the Human Nk Cell Triggering Receptor Nkp46 Ectodomain
Biochem.Biophys.Res.Commun., 309, 2003
1YJU
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Solution structure of the apo form of the sixth soluble domain of Menkes protein
分子名称: Copper-transporting ATPase 1
著者Banci, L, Bertini, I, Cantini, F, Migliardi, M, Rosato, A, Wang, S, Structural Proteomics in Europe (SPINE)
登録日2005-01-15
公開日2006-01-03
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献An atomic-level investigation of the disease-causing A629P mutant of the Menkes protein, ATP7A
J.Mol.Biol., 352, 2005
1YJT
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BU of 1yjt by Molmil
Solution structure of the Cu(I) form of the sixth soluble domain A69P mutant of Menkes protein
分子名称: COPPER (I) ION, Copper-transporting ATPase 1
著者Banci, L, Bertini, I, Cantini, F, Migliardi, M, Rosato, A, Wang, S.
登録日2005-01-15
公開日2006-01-03
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献An atomic-level investigation of the disease-causing A629P mutant of the Menkes protein, ATP7A
J.Mol.Biol., 352, 2005
1YJR
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BU of 1yjr by Molmil
Solution structure of the apo form of the sixth soluble domain A69P mutant of Menkes protein
分子名称: Copper-transporting ATPase 1
著者Banci, L, Bertini, I, Cantini, F, Migliardi, M, Rosato, A, Wang, S, Structural Proteomics in Europe (SPINE)
登録日2005-01-15
公開日2006-01-03
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献An atomic-level investigation of the disease-causing A629P mutant of the Menkes protein, ATP7A
J.Mol.Biol., 352, 2005
1YJV
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BU of 1yjv by Molmil
Solution structure of the Cu(I) form of the sixth soluble domain of Menkes protein
分子名称: COPPER (I) ION, Copper-transporting ATPase 1
著者Banci, L, Bertini, I, Cantini, F, Migliardi, M, Rosato, A, Wang, S.
登録日2005-01-15
公開日2006-01-03
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献An atomic-level investigation of the disease-causing A629P mutant of the Menkes protein, ATP7A
J.Mol.Biol., 352, 2005
5E4A
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BU of 5e4a by Molmil
Human transthyretin (TTR) complexed with (2,7-Dichloro-fluoren-9-ylideneaminooxy)-acetic acid.
分子名称: Transthyretin, {[(2,7-dichloro-9H-fluoren-9-ylidene)amino]oxy}acetic acid
著者Ciccone, L, Nencetti, S, Rossello, A, Orlandini, E, Stura, E.A.
登録日2015-10-05
公開日2016-03-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.33 Å)
主引用文献Synthesis and structural analysis of halogen substituted fibril formation inhibitors of Human Transthyretin (TTR).
J Enzyme Inhib Med Chem, 31, 2016
1H4K
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Sulfurtransferase from Azotobacter vinelandii in complex with hypophosphite
分子名称: 1,2-ETHANEDIOL, HYPOPHOSPHITE, SULFATE ION, ...
著者Bordo, D, Forlani, F, Spallarossa, A, Colnaghi, R, Carpen, A, Pagani, S, Bolognesi, M.
登録日2001-05-11
公開日2002-05-16
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献A Persulfurated Cysteine Promotes Active Site Reactivity in Azotobacter Vinelandii Rhodanse
Biol.Chem., 382, 2001
5E4O
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Human transthyretin (TTR) complexed with (Z)-((3,4-Dichloro-phenyl)-methyleneaminooxy)-acetic acid
分子名称: ({(Z)-[(3,4-dichlorophenyl)(phenyl)methylidene]amino}oxy)acetic acid, Transthyretin
著者Ciccone, L, Savko, M, Nencetti, S, Rossello, A, Orlandini, E, Stura, E.A.
登録日2015-10-06
公開日2016-03-23
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Synthesis and structural analysis of halogen substituted fibril formation inhibitors of Human Transthyretin (TTR).
J Enzyme Inhib Med Chem, 31, 2016
5E23
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Human transthyretin (TTR) complexed with (2,7-Dibromo-fluoren-9-ylideneaminooxy)-acetic acid
分子名称: DIMETHYL SULFOXIDE, Transthyretin, {[(2,7-dibromo-9H-fluoren-9-ylidene)amino]oxy}acetic acid
著者Ciccone, L, Nencetti, S, Rossello, A, Orlandini, E, Stura, E.A.
登録日2015-09-30
公開日2016-03-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.41 Å)
主引用文献Synthesis and structural analysis of halogen substituted fibril formation inhibitors of Human Transthyretin (TTR).
J Enzyme Inhib Med Chem, 31, 2016
1HKF
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The three dimensional structure of NK cell receptor Nkp44, a triggering partner in natural cytotoxicity
分子名称: NK CELL ACTIVATING RECEPTOR
著者Ponassi, M, Cantoni, C, Biassoni, R, Conte, R, Spallarossa, A, Moretta, A, Moretta, L, Bolognesi, M, Bordo, D.
登録日2003-03-10
公開日2003-06-11
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The Three-Dimensional Structure of the Human Nk Cell Receptor Nkp44, a Triggering Partner in Natural Cytotoxicity
Structure, 11, 2003
1HKS
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SOLUTION STRUCTURE OF THE DNA-BINDING DOMAIN OF DROSOPHILA HEAT SHOCK TRANSCRIPTION FACTOR
分子名称: HEAT-SHOCK TRANSCRIPTION FACTOR
著者Vuister, G.W, Kim, S.-J, Orosz, A, Marquardt, J.L, Wu, C, Bax, A.
登録日1994-07-18
公開日1994-09-30
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of the DNA-binding domain of Drosophila heat shock transcription factor.
Nat.Struct.Biol., 1, 1994
1HKT
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SOLUTION STRUCTURE OF THE DNA-BINDING DOMAIN OF DROSOPHILA HEAT SHOCK TRANSCRIPTION FACTOR
分子名称: HEAT-SHOCK TRANSCRIPTION FACTOR
著者Vuister, G.W, Kim, S.-J, Orosz, A, Marquardt, J.L, Wu, C, Bax, A.
登録日1994-07-18
公開日1994-09-30
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of the DNA-binding domain of Drosophila heat shock transcription factor.
Nat.Struct.Biol., 1, 1994

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