7QQX
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![BU of 7qqx by Molmil](/molmil-images/mine/7qqx) | SpCas9 bound to FANCF off-target5 DNA substrate | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, FANCF off-target5 non-target strand, FANCF off-target5 target strand, ... | 著者 | Pacesa, M, Jinek, M. | 登録日 | 2022-01-10 | 公開日 | 2022-10-26 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural basis for Cas9 off-target activity. Cell, 185, 2022
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7QR0
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7QQZ
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![BU of 7qqz by Molmil](/molmil-images/mine/7qqz) | SpCas9 bound to FANCF off-target7 DNA substrate | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, FANCF off-target7 non-target strand, FANCF off-target7 target strand, ... | 著者 | Pacesa, M, Jinek, M. | 登録日 | 2022-01-10 | 公開日 | 2022-10-26 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structural basis for Cas9 off-target activity. Cell, 185, 2022
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7QQW
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![BU of 7qqw by Molmil](/molmil-images/mine/7qqw) | SpCas9 bound to FANCF off-target4 DNA substrate | 分子名称: | CRISPR-associated endonuclease Cas9/Csn1, FANCF off-target4 non-target strand, FANCF off-target4 target strand, ... | 著者 | Pacesa, M, Jinek, M. | 登録日 | 2022-01-10 | 公開日 | 2022-10-26 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural basis for Cas9 off-target activity. Cell, 185, 2022
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7QR1
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7QR7
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![BU of 7qr7 by Molmil](/molmil-images/mine/7qr7) | |
8S9V
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![BU of 8s9v by Molmil](/molmil-images/mine/8s9v) | |
8S9X
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8S9T
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8S9U
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6HUD
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4R97
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![BU of 4r97 by Molmil](/molmil-images/mine/4r97) | Crystal structure of the Fab fragment of KKO | 分子名称: | GLYCEROL, ZINC ION, platelet factor 4 antibody KKO heavy chain, ... | 著者 | Cai, Z, Zhu, Z, Liu, Q, Greene, M.I. | 登録日 | 2014-09-03 | 公開日 | 2015-12-16 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Atomic description of the immune complex involved in heparin-induced thrombocytopenia. Nat Commun, 6, 2015
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4R9W
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![BU of 4r9w by Molmil](/molmil-images/mine/4r9w) | Crystal structure of platelet factor 4 complexed with fondaparinux | 分子名称: | 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranoside, Platelet factor 4 | 著者 | Cai, Z, Zhu, Z, Liu, Q, Greene, M.I. | 登録日 | 2014-09-08 | 公開日 | 2015-12-16 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Atomic description of the immune complex involved in heparin-induced thrombocytopenia. Nat Commun, 6, 2015
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4R9Y
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![BU of 4r9y by Molmil](/molmil-images/mine/4r9y) | Crystal structure of KKOFab in complex with platelet factor 4 | 分子名称: | Platelet factor 4, Platelet factor 4 antibody KKO heavy chain, Platelet factor 4 antibody KKO light chain | 著者 | Cai, Z, Zhu, Z, Liu, Q, Greene, M.I. | 登録日 | 2014-09-08 | 公開日 | 2015-12-16 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (4.11 Å) | 主引用文献 | Atomic description of the immune complex involved in heparin-induced thrombocytopenia. Nat Commun, 6, 2015
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4XI5
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![BU of 4xi5 by Molmil](/molmil-images/mine/4xi5) | gHgL of varicella-zoster virus in complex with human neutralizing antibodies | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein H, Envelope glycoprotein L, ... | 著者 | Xing, Y. | 登録日 | 2015-01-06 | 公開日 | 2015-05-13 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | 主引用文献 | A site of varicella-zoster virus vulnerability identified by structural studies of neutralizing antibodies bound to the glycoprotein complex gHgL. Proc.Natl.Acad.Sci.USA, 112, 2015
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4XHJ
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![BU of 4xhj by Molmil](/molmil-images/mine/4xhj) | gHgL of Varicella-zoster virus in complex with human neutralizing antibodies. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein H, ... | 著者 | Xing, Y. | 登録日 | 2015-01-05 | 公開日 | 2015-05-13 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.156 Å) | 主引用文献 | A site of varicella-zoster virus vulnerability identified by structural studies of neutralizing antibodies bound to the glycoprotein complex gHgL. Proc.Natl.Acad.Sci.USA, 112, 2015
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5HCV
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5I4V
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![BU of 5i4v by Molmil](/molmil-images/mine/5i4v) | Discovery of novel, orally efficacious Liver X Receptor (LXR) beta agonists | 分子名称: | Oxysterols receptor LXR-beta,Nuclear receptor coactivator 2, Retinoic acid receptor RXR-beta,Nuclear receptor coactivator 2, {2-[(2R)-4-[4-(hydroxymethyl)-3-(methylsulfonyl)phenyl]-2-(propan-2-yl)piperazin-1-yl]-4-(trifluoromethyl)pyrimidin-5-yl}methanol | 著者 | Chen, G, McKeever, B.M. | 登録日 | 2016-02-12 | 公開日 | 2016-06-29 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | 主引用文献 | Discovery of a Novel, Orally Efficacious Liver X Receptor (LXR) beta Agonist. J.Med.Chem., 59, 2016
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8P5E
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8P62
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8P63
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2VPR
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![BU of 2vpr by Molmil](/molmil-images/mine/2vpr) | Tet repressor class H in complex with 5a,6- anhydrotetracycline-Mg | 分子名称: | 5A,6-ANHYDROTETRACYCLINE, MAGNESIUM ION, SULFATE ION, ... | 著者 | Schuldt, L, Palm, G, Hinrichs, W. | 登録日 | 2008-03-03 | 公開日 | 2008-03-11 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | Tet Repressor Induction by Tetracycline: A Molecular Dynamics, Continuum Electrostatics, and Crystallographic Study J.Mol.Biol., 378, 2008
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