1CGC
 
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4KTD
 | | Fab fragment of HIV vaccine-elicited CD4bs-directed antibody, GE136, from non-human primate | | 分子名称: | GE136 Heavy Chain Fab, GE136 Light Chain Fab, GLYCEROL, ... | | 著者 | Poulsen, C, Tran, K, Standfield, R, Wyatt, R.T. | | 登録日 | 2013-05-20 | | 公開日 | 2014-02-05 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Vaccine-elicited primate antibodies use a distinct approach to the HIV-1 primary receptor binding site informing vaccine redesign.
Proc.Natl.Acad.Sci.USA, 111, 2014
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122D
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123D
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3C41
 | | ABC protein ArtP in complex with AMP-PNP/Mg2+ | | 分子名称: | Amino acid ABC transporter (ArtP), MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | 著者 | Thaben, P.F, Eckey, V, Scheffel, F, Saenger, W, Schneider, E, Vahedi-Faridi, A. | | 登録日 | 2008-01-29 | | 公開日 | 2009-02-03 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Crystal Structures of the ATP-binding cassette (ABC) Protein ArtP from Geobacillus stearothermophilus in complexes with nucleotides and nucleotide analogs reveal an intermediate semiclosed dimer in the post hydrolyses state and an asymmetry in the dimerisation region
To be Published
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3C4J
 | | ABC protein ArtP in complex with ATP-gamma-S | | 分子名称: | Amino acid ABC transporter (ArtP), MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | | 著者 | Thaben, P.F, Eckey, V, Scheffel, F, Saenger, W, Schneider, E, Vahedi-Faridi, A. | | 登録日 | 2008-01-30 | | 公開日 | 2009-02-03 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | | 主引用文献 | Crystal Structures of the ATP-binding cassette (ABC) Protein ArtP from Geobacillus stearothermophilus in complexes with nucleotides and nucleotide analogs reveal an intermediate semiclosed dimer in the post hydrolyses state and an asymmetry in the dimerisation region
To be Published
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2Z9A
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3GYH
 | | Crystal Structure Analysis of S. Pombe ATL in complex with damaged DNA containing POB | | 分子名称: | 1-PYRIDIN-3-YLBUTAN-1-ONE, Alkyltransferase-like protein 1, DNA (5'-D(*CP*TP*AP*CP*TP*AP*GP*CP*CP*AP*TP*GP*G)-3'), ... | | 著者 | Tubbs, J.L, Arvai, A.S, Tainer, J.A, Shin, D.S. | | 登録日 | 2009-04-03 | | 公開日 | 2009-06-16 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Flipping of alkylated DNA damage bridges base and nucleotide excision repair.
Nature, 459, 2009
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7EKB
 | | Crystal structure of 4E10 modified with pyrene acetamide | | 分子名称: | ACETATE ION, Fab region of the heavy chain of broadly neutralizing antibody anti-HIV-1 4E10, Fab region of the light chain of the broadly neutralizing anti-HIV-1 antibody 4E10, ... | | 著者 | Caaveiro, J.M.M, Rujas, E, Nieva, J.L. | | 登録日 | 2021-04-05 | | 公開日 | 2021-08-11 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Focal accumulation of aromaticity at the CDRH3 loop mitigates 4E10 polyreactivity without altering its HIV neutralization profile.
Iscience, 24, 2021
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7EKK
 | | Anti-HIV-1 broadly neutralizing antibody delta-loop 4E10 modified with pyrene acetamide | | 分子名称: | AMMONIUM ION, CHLORIDE ION, GLYCEROL, ... | | 著者 | Caaveiro, J.M.M, Rujas, E, Nieva, J.L. | | 登録日 | 2021-04-05 | | 公開日 | 2021-08-11 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Focal accumulation of aromaticity at the CDRH3 loop mitigates 4E10 polyreactivity without altering its HIV neutralization profile.
Iscience, 24, 2021
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5JDT
 | | Structure of Spin-labelled T4 lysozyme mutant L118C-R1 at 100K | | 分子名称: | AZIDE ION, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... | | 著者 | Loll, B, Consentius, P, Gohlke, U, Mueller, R, Kaupp, M, Heinemann, U, Wahl, M.C, Risse, T. | | 登録日 | 2016-04-17 | | 公開日 | 2016-09-28 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1 Å) | | 主引用文献 | Tracking Transient Conformational States of T4 Lysozyme at Room Temperature Combining X-ray Crystallography and Site-Directed Spin Labeling.
J.Am.Chem.Soc., 138, 2016
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6U9U
 | | Structure of GM9_TH8seq732127 FAB | | 分子名称: | 1,2-ETHANEDIOL, FORMIC ACID, GM9_TH8seq732127 FAB heavy chain, ... | | 著者 | Singh, S, Liban, T.J, Pancera, M. | | 登録日 | 2019-09-09 | | 公開日 | 2019-11-06 | | 最終更新日 | 2019-12-25 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | Extensive dissemination and intraclonal maturation of HIV Env vaccine-induced B cell responses.
J.Exp.Med., 217, 2020
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6U3Z
 | | Structure of VD20_5A4 Fab | | 分子名称: | ACETATE ION, CHLORIDE ION, GLYCEROL, ... | | 著者 | Dionne, G, Shapiro, L. | | 登録日 | 2019-08-22 | | 公開日 | 2019-11-20 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.99002314 Å) | | 主引用文献 | Extensive dissemination and intraclonal maturation of HIV Env vaccine-induced B cell responses.
J.Exp.Med., 217, 2020
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4IUM
 | | Equine arteritis virus papain-like protease 2 (PLP2) covalently bound to ubiquitin | | 分子名称: | GLYCEROL, Ubiquitin, ZINC ION, ... | | 著者 | Bailey-Elkin, B.A, James, T.W, Mark, B.L. | | 登録日 | 2013-01-21 | | 公開日 | 2013-02-13 | | 最終更新日 | 2013-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Deubiquitinase function of arterivirus papain-like protease 2 suppresses the innate immune response in infected host cells.
Proc.Natl.Acad.Sci.USA, 110, 2013
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3LS3
 | | Padron0.9-ON (fluorescent state) | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, Padron0.9, ... | | 著者 | Brakemann, T, Weber, G, Trowitzsch, S, Wahl, M.C, Jakobs, S. | | 登録日 | 2010-02-12 | | 公開日 | 2010-03-16 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Molecular basis of the light-driven switching of the photochromic fluorescent protein Padron.
J.Biol.Chem., 285, 2010
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6TEO
 | | Crystal structure of a yeast Snu114-Prp8 complex | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Pre-mRNA-splicing factor 8, ... | | 著者 | Ganichkin, O, Jia, J, Loll, B, Absmeier, E, Wahl, M.C. | | 登録日 | 2019-11-12 | | 公開日 | 2020-03-18 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | A Snu114-GTP-Prp8 module forms a relay station for efficient splicing in yeast.
Nucleic Acids Res., 48, 2020
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5CSW
 | | B-RAF in complex with Dabrafenib | | 分子名称: | CHLORIDE ION, Dabrafenib, Serine/threonine-protein kinase B-raf | | 著者 | Bader, G, Stadtmuller, H, Steurer, S. | | 登録日 | 2015-07-23 | | 公開日 | 2016-03-09 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | | 主引用文献 | A Novel RAF Kinase Inhibitor with DFG-Out-Binding Mode: High Efficacy in BRAF-Mutant Tumor Xenograft Models in the Absence of Normal Tissue Hyperproliferation.
Mol.Cancer Ther., 15, 2016
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5CSX
 | | CRYSTAL STRUCTURE OF B-RAF IN COMPLEX WITH BI 882370 | | 分子名称: | N-(3-{5-[(1-ethylpiperidin-4-yl)(methyl)amino]-3-(pyrimidin-5-yl)-1H-pyrrolo[3,2-b]pyridin-1-yl}-2,4-difluorophenyl)propane-1-sulfonamide, Serine/threonine-protein kinase B-raf, alpha-D-glucopyranose | | 著者 | Bader, G, Stadtmuller, H, Steurer, S. | | 登録日 | 2015-07-23 | | 公開日 | 2016-03-09 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | A Novel RAF Kinase Inhibitor with DFG-Out-Binding Mode: High Efficacy in BRAF-Mutant Tumor Xenograft Models in the Absence of Normal Tissue Hyperproliferation.
Mol.Cancer Ther., 15, 2016
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6EK4
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6EL1
 | | YaxAB pore complex | | 分子名称: | YaxA, YaxB | | 著者 | Braeuning, B, Bertosin, E, Dietz, H, Groll, M. | | 登録日 | 2017-09-27 | | 公開日 | 2018-05-16 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (6.1 Å) | | 主引用文献 | Structure and mechanism of the two-component alpha-helical pore-forming toxin YaxAB.
Nat Commun, 9, 2018
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6EK7
 | | YaxA from Yersinia enterocolitica | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, YaxA | | 著者 | Braeuning, B, Groll, M. | | 登録日 | 2017-09-25 | | 公開日 | 2018-05-16 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure and mechanism of the two-component alpha-helical pore-forming toxin YaxAB.
Nat Commun, 9, 2018
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3CUJ
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3CUF
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3CUG
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3CUH
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