7Y5T
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![BU of 7y5t by Molmil](/molmil-images/mine/7y5t) | CryoEM structure of PS1-containing gamma-secretase in complex with MRK-560 | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Guo, X, Wang, Y, Zhou, J, Jin, C, Wang, J, Jia, B, Jing, D, Yan, C, Lei, J, Zhou, R, Shi, Y. | 登録日 | 2022-06-17 | 公開日 | 2022-11-02 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Molecular basis for isoform-selective inhibition of presenilin-1 by MRK-560. Nat Commun, 13, 2022
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7Y5Z
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![BU of 7y5z by Molmil](/molmil-images/mine/7y5z) | CryoEM structure of human PS2-containing gamma-secretase | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Guo, X, Wang, Y, Zhou, J, Jin, C, Wang, J, Jia, B, Jing, D, Yan, C, Lei, J, Zhou, R, Shi, Y. | 登録日 | 2022-06-18 | 公開日 | 2022-11-02 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Molecular basis for isoform-selective inhibition of presenilin-1 by MRK-560. Nat Commun, 13, 2022
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4N0G
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![BU of 4n0g by Molmil](/molmil-images/mine/4n0g) | Crystal Structure of PYL13-PP2CA complex | 分子名称: | Abscisic acid receptor PYL13, MAGNESIUM ION, Protein phosphatase 2C 37, ... | 著者 | Li, W, Wang, L, Sheng, X, Yan, C, Zhou, R, Hang, J, Yin, P, Yan, N. | 登録日 | 2013-10-01 | 公開日 | 2013-11-13 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.382 Å) | 主引用文献 | Molecular basis for the selective and ABA-independent inhibition of PP2CA by PYL13 Cell Res., 23, 2013
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5MP2
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![BU of 5mp2 by Molmil](/molmil-images/mine/5mp2) | XcpQN012 in complex with VHH04 | 分子名称: | Camelid nanobody VHH04, Type II secretion system protein D | 著者 | Trinh, T.T.N, Roussel, A, Douzi, B, Voulhoux, R. | 登録日 | 2016-12-15 | 公開日 | 2017-12-13 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Unraveling the Self-Assembly of the Pseudomonas aeruginosa XcpQ Secretin Periplasmic Domain Provides New Molecular Insights into Type II Secretion System Secreton Architecture and Dynamics. MBio, 8, 2017
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4PPS
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![BU of 4pps by Molmil](/molmil-images/mine/4pps) | Crystal Structure of the Estrogen Receptor alpha Ligand-binding Domain in Complex with an A-CD ring estrogen derivative | 分子名称: | (1S,3aR,5R,7aS)-5-(4-hydroxyphenyl)-7a-methyloctahydro-1H-inden-1-ol, Estrogen receptor, Nuclear receptor coactivator 2 | 著者 | Nwachukwu, J.C, Srinivasan, S, Bruno, N.E, Parent, A.A, Hughes, T.S, Pollock, J.A, Gjyshi, O, Cavett, V, Nowak, J, Garcia-Ordonez, R.D, Houtman, R, Griffin, P.R, Kojetin, D.J, Katzenellenbogen, J.A, Conkright, M.D, Nettles, K.W. | 登録日 | 2014-02-27 | 公開日 | 2014-05-07 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.929 Å) | 主引用文献 | Resveratrol modulates the inflammatory response via an estrogen receptor-signal integration network. Elife, 3, 2014
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4PP6
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![BU of 4pp6 by Molmil](/molmil-images/mine/4pp6) | Crystal Structure of the Estrogen Receptor alpha Ligand-binding Domain in Complex with Resveratrol | 分子名称: | Estrogen receptor, Nuclear receptor coactivator 2, RESVERATROL | 著者 | Nwachukwu, J.C, Srinivasan, S, Bruno, N.E, Parent, A.A, Hughes, T.S, Pollock, J.A, Gjyshi, O, Cavett, V, Nowak, J, Garcia-Ordonez, R.D, Houtman, R, Griffin, P.R, Kojetin, D.J, Katzenellenbogen, J.A, Conkright, M.D, Nettles, K.W. | 登録日 | 2014-02-26 | 公開日 | 2014-05-07 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.201 Å) | 主引用文献 | Resveratrol modulates the inflammatory response via an estrogen receptor-signal integration network. Elife, 3, 2014
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4PPP
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![BU of 4ppp by Molmil](/molmil-images/mine/4ppp) | Crystal Structure of the Estrogen Receptor alpha Ligand-binding Domain in Complex with Fluoro-Resveratrol | 分子名称: | 5-[(E)-2-(3-fluoro-4-hydroxyphenyl)ethenyl]benzene-1,3-diol, Estrogen receptor, Nuclear receptor coactivator 2 | 著者 | Nwachukwu, J.C, Srinivasan, S, Bruno, N.E, Parent, A.A, Hughes, T.S, Pollock, J.A, Gjyshi, O, Cavett, V, Nowak, J, Garcia-Ordonez, R.D, Houtman, R, Griffin, P.R, Kojetin, D.J, Katzenellenbogen, J.A, Conkright, M.D, Nettles, K.W. | 登録日 | 2014-02-27 | 公開日 | 2014-05-07 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.686 Å) | 主引用文献 | Resveratrol modulates the inflammatory response via an estrogen receptor-signal integration network. Elife, 3, 2014
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7D8X
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![BU of 7d8x by Molmil](/molmil-images/mine/7d8x) | CryoEM structure of human gamma-secretase in complex with E2012 and L685458 | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1-[(1S)-1-(4-fluorophenyl)ethyl]-3-[[3-methoxy-4-(4-methylimidazol-1-yl)phenyl]methylidene]piperidin-2-one, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Yang, G, Zhou, R, Guo, X, Lei, J, Yan, C, Shi, Y. | 登録日 | 2020-10-11 | 公開日 | 2021-01-27 | 最終更新日 | 2021-02-03 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Structural basis of gamma-secretase inhibition and modulation by small molecule drugs. Cell, 184, 2021
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2EUA
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![BU of 2eua by Molmil](/molmil-images/mine/2eua) | Structure and Mechanism of MenF, the Menaquinone-Specific Isochorismate Synthase from Escherichia Coli | 分子名称: | D(-)-TARTARIC ACID, Menaquinone-specific isochorismate synthase | 著者 | Kolappan, S, Kisker, C, Zwahlen, J, Zhou, R, Tonge, P.J. | 登録日 | 2005-10-28 | 公開日 | 2006-12-05 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Lysine 190 is the catalytic base in MenF, the menaquinone-specific isochorismate synthase from Escherichia coli: implications for an enzyme family. Biochemistry, 46, 2007
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2I6Y
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![BU of 2i6y by Molmil](/molmil-images/mine/2i6y) | Structure and Mechanism of Mycobacterium tuberculosis Salicylate Synthase, MbtI | 分子名称: | Anthranilate synthase component I, putative | 著者 | Zwahlen, J, Subramaniapillai, K, Zhou, R, Kisker, C, Tonge, P.J. | 登録日 | 2006-08-29 | 公開日 | 2007-06-19 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure and mechanism of MbtI, the salicylate synthase from Mycobacterium tuberculosis Biochemistry, 46, 2007
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2KEP
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![BU of 2kep by Molmil](/molmil-images/mine/2kep) | Solution structure of XcpT, the main component of the type 2 secretion system of Pseudomonas aeruginosa | 分子名称: | General secretion pathway protein G | 著者 | Alphonse, S, Durand, E, Douzi, B, Darbon, H, Filloux, A, Voulhoux, R, Bernard, C. | 登録日 | 2009-02-02 | 公開日 | 2009-10-06 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the Pseudomonas aeruginosa XcpT pseudopilin, a major component of the type II secretion system J.Struct.Biol., 2009
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7C22
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1CAP
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![BU of 1cap by Molmil](/molmil-images/mine/1cap) | CONFORMATION AND MOLECULAR ORGANIZATION IN FIBERS OF THE CAPSULAR POLYSACCHARIDE FROM ESCHERICHIA COLI M41 MUTANT | 分子名称: | alpha-D-mannopyranose-(1-3)-beta-D-glucopyranose-(1-3)-[4,6-O-[(1S)-1-carboxyethylidene]-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-4)]beta-D-glucopyranuronic acid-(1-3)-beta-D-galactopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-glucopyranose-(1-3)-[4,6-O-[(1S)-1-carboxyethylidene]-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-4)]beta-D-glucopyranuronic acid-(1-3)-beta-D-galactopyranose | 著者 | Arnott, S. | 登録日 | 1978-05-23 | 公開日 | 1980-03-28 | 最終更新日 | 2024-02-07 | 実験手法 | FIBER DIFFRACTION (3 Å) | 主引用文献 | Conformation and molecular organization in fibers of the capsular polysaccharide from Escherichia coli M41 mutant. J.Mol.Biol., 109, 1977
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2MWA
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2MWF
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![BU of 2mwf by Molmil](/molmil-images/mine/2mwf) | |
2MWB
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![BU of 2mwb by Molmil](/molmil-images/mine/2mwb) | FBP28 WW2 mutant W457F | 分子名称: | Transcription elongation regulator 1 | 著者 | Macias, M.J, Scheraga, H, Sunol, D, Todorovski, T. | 登録日 | 2014-11-03 | 公開日 | 2014-12-03 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Folding kinetics of WW domains with the united residue force field for bridging microscopic motions and experimental measurements. Proc.Natl.Acad.Sci.USA, 111, 2014
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2MWD
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2MW9
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2MWE
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![BU of 2mwe by Molmil](/molmil-images/mine/2mwe) | NMR structure of FBP28 WW2 mutant Y438R, L453A DNDC | 分子名称: | Transcription elongation regulator 1 | 著者 | Macias, M.J, Scheraga, H, Sunol, D, Todorovski, T. | 登録日 | 2014-11-04 | 公開日 | 2014-12-03 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Folding kinetics of WW domains with the united residue force field for bridging microscopic motions and experimental measurements. Proc.Natl.Acad.Sci.USA, 111, 2014
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7YDY
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![BU of 7ydy by Molmil](/molmil-images/mine/7ydy) | SARS-CoV-2 Spike (6P) in complex with 1 R1-32 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of R1-32 Fab, ... | 著者 | Liu, B, Gao, X, Li, Z, Chen, X, He, J, Chen, L, Xiong, X. | 登録日 | 2022-07-04 | 公開日 | 2022-08-24 | 最終更新日 | 2023-07-26 | 実験手法 | ELECTRON MICROSCOPY (4.75 Å) | 主引用文献 | SARS-CoV-2 Delta and Omicron variants evade population antibody response by mutations in a single spike epitope. Nat Microbiol, 7, 2022
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7YEG
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![BU of 7yeg by Molmil](/molmil-images/mine/7yeg) | SARS-CoV-2 Spike (6P) in complex with 3 R1-32 Fabs and 3 ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | 著者 | Liu, B, Gao, X, Li, Z, Chen, X, He, J, Chen, L, Xiong, X. | 登録日 | 2022-07-05 | 公開日 | 2022-08-24 | 最終更新日 | 2023-07-26 | 実験手法 | ELECTRON MICROSCOPY (3.73 Å) | 主引用文献 | SARS-CoV-2 Delta and Omicron variants evade population antibody response by mutations in a single spike epitope. Nat Microbiol, 7, 2022
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7YDI
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![BU of 7ydi by Molmil](/molmil-images/mine/7ydi) | SARS-CoV-2 Spike (6P) in complex with 3 R1-32 Fabs and 3 ACE2, focused refinement of RBD region | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of R1-32, Light chain of R1-32, ... | 著者 | Liu, B, Gao, X, Li, Z, Chen, X, He, J, Chen, L, Xiong, X. | 登録日 | 2022-07-04 | 公開日 | 2022-08-24 | 最終更新日 | 2023-07-26 | 実験手法 | ELECTRON MICROSCOPY (3.98 Å) | 主引用文献 | SARS-CoV-2 Delta and Omicron variants evade population antibody response by mutations in a single spike epitope. Nat Microbiol, 7, 2022
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7YE5
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![BU of 7ye5 by Molmil](/molmil-images/mine/7ye5) | SARS-CoV-2 Spike (6P) in complex with 2 R1-32 Fabs | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of R1-32 Fab, ... | 著者 | Liu, B, Gao, X, Li, Z, Chen, X, He, J, Chen, L, Xiong, X. | 登録日 | 2022-07-05 | 公開日 | 2022-08-24 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (6.75 Å) | 主引用文献 | SARS-CoV-2 Delta and Omicron variants evade population antibody response by mutations in a single spike epitope. Nat Microbiol, 7, 2022
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5VIC
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![BU of 5vic by Molmil](/molmil-images/mine/5vic) | Crystal structure of anti-Zika antibody Z004 bound to DENV-1 Envelope protein DIII | 分子名称: | Dengue 1 Envelope DIII domain, Fab heavy chain, Fab light chain | 著者 | Keeffe, J.R, West Jr, A.P, Gristick, H.B, Bjorkman, P.J. | 登録日 | 2017-04-14 | 公開日 | 2017-05-03 | 最終更新日 | 2017-05-17 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Recurrent Potent Human Neutralizing Antibodies to Zika Virus in Brazil and Mexico. Cell, 169, 2017
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5VIG
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![BU of 5vig by Molmil](/molmil-images/mine/5vig) | Crystal structure of anti-Zika antibody Z006 bound to Zika virus envelope protein DIII | 分子名称: | CITRATE ANION, Fab heavy chain, Fab light chain, ... | 著者 | Keeffe, J.R, West Jr, A.P, Gristick, H.B, Bjorkman, P.J. | 登録日 | 2017-04-16 | 公開日 | 2017-05-03 | 最終更新日 | 2017-05-17 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Recurrent Potent Human Neutralizing Antibodies to Zika Virus in Brazil and Mexico. Cell, 169, 2017
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