7SX4
| Human NALCN-FAM155A-UNC79-UNC80 channelosome with CaM bound, conformation 2/2 | 分子名称: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Kschonsak, M, Chua, H.C, Weidling, C, Chakouri, N, Noland, C.L, Schott, K, Chang, T, Tam, C, Patel, N, Arthur, C.P, Leitner, A, Ben-Johny, M, Ciferri, C, Pless, S.A, Payandeh, J. | 登録日 | 2021-11-22 | 公開日 | 2021-12-29 | 最終更新日 | 2022-03-16 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural architecture of the human NALCN channelosome. Nature, 603, 2022
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4ZA1
| Crystal Structure of NosA Involved in Nosiheptide Biosynthesis | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, NosA | 著者 | Liu, S, Guo, H, Zhang, T, Han, L, Yao, P, Zhang, Y, Rong, N, Yu, Y, Lan, W, Wang, C, Ding, J, Wang, R, Liu, W, Cao, C. | 登録日 | 2015-04-13 | 公開日 | 2015-08-19 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure-based Mechanistic Insights into Terminal Amide Synthase in Nosiheptide-Represented Thiopeptides Biosynthesis Sci Rep, 5, 2015
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3NCY
| X-ray crystal structure of an arginine agmatine antiporter (AdiC) in complex with a Fab fragment | 分子名称: | AdiC, Fab Heavy chain, Fab Light chain | 著者 | Fang, Y, Jayaram, H, Shane, T, Komalkova-Partensky, L, Wu, F, Williams, C, Xiong, Y, Miller, C. | 登録日 | 2010-06-06 | 公開日 | 2010-08-18 | 最終更新日 | 2019-07-17 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structure of a prokaryotic virtual proton pump at 3.2 A resolution. Nature, 460, 2009
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8HZW
| The NMR structure of noursinH11W peptide | 分子名称: | noursinH11W | 著者 | Yao, H, Li, Y, Zhang, T, Gao, J, Wang, H. | 登録日 | 2023-01-09 | 公開日 | 2023-05-31 | 最終更新日 | 2024-05-08 | 実験手法 | SOLUTION NMR | 主引用文献 | Discovery and biosynthesis of tricyclic copper-binding ribosomal peptides containing histidine-to-butyrine crosslinks. Nat Commun, 14, 2023
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6D0K
| Crystal structure of a CLC-type fluoride/proton antiporter, E118Q mutant | 分子名称: | (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, CLC-type fluoride/proton antiporter, DECYL-BETA-D-MALTOPYRANOSIDE, ... | 著者 | Last, N.B, Stockbridge, R.B, Wilson, A.E, Shane, T, Kolmakova-Partensky, L, Koide, A, Koide, S, Miller, C. | 登録日 | 2018-04-10 | 公開日 | 2018-07-04 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | 主引用文献 | A CLC-type F-/H+antiporter in ion-swapped conformations. Nat. Struct. Mol. Biol., 25, 2018
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6D0J
| Crystal structure of a CLC-type fluoride/proton antiporter | 分子名称: | (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, CLC-type fluoride/proton antiporter, DECYL-BETA-D-MALTOPYRANOSIDE, ... | 著者 | Last, N.B, Stockbridge, R.B, Wilson, A.E, Shane, T, Kolmakova-Partensky, L, Koide, A, Koide, S, Miller, C. | 登録日 | 2018-04-10 | 公開日 | 2018-07-04 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | A CLC-type F-/H+antiporter in ion-swapped conformations. Nat. Struct. Mol. Biol., 25, 2018
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8Z90
| Cryo-EM structure of Thogoto virus polymerase in transcription initiation conformation 2 | 分子名称: | PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, Polymerase acidic protein, Polymerase basic protein 2, ... | 著者 | Xue, L, Chang, T, Li, Z, Zhao, H, Li, M, He, J, Chen, X, Xiong, X. | 登録日 | 2024-04-22 | 公開日 | 2024-05-29 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.87 Å) | 主引用文献 | Cryo-EM structures of Thogoto virus polymerase reveal unique RNA transcription and replication mechanisms among orthomyxoviruses. Nat Commun, 15, 2024
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8Z98
| Cryo-EM structure of Thogoto virus polymerase in a transcription reception conformation | 分子名称: | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-(2'-O-METHYL)-ADENOSINE, Polymerase acidic protein, Polymerase basic protein 2, ... | 著者 | Xue, L, Chang, T, Li, Z, Zhao, H, Li, M, He, J, Chen, X, Xiong, X. | 登録日 | 2024-04-22 | 公開日 | 2024-05-29 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.52 Å) | 主引用文献 | Cryo-EM structures of Thogoto virus polymerase reveal unique RNA transcription and replication mechanisms among orthomyxoviruses. Nat Commun, 15, 2024
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8Z9R
| Cryo-EM structure of Thogoto virus polymerase in a replication elongation-reception conformation | 分子名称: | Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-D(*(ATP))-R(P*GP*CP*AP*AP*AP*AP*AP*CP*A)-3'), ... | 著者 | Xue, L, Chang, T, Li, Z, Zhao, H, Li, M, He, J, Chen, X, Xiong, X. | 登録日 | 2024-04-23 | 公開日 | 2024-05-29 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.58 Å) | 主引用文献 | Cryo-EM structures of Thogoto virus polymerase reveal unique RNA transcription and replication mechanisms among orthomyxoviruses. Nat Commun, 15, 2024
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8Z8N
| Cryo-EM structure of Thogoto virus polymerase in transcription pre-initiation conformation 3 | 分子名称: | Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(*AP*GP*AP*GP*AP*AP*AP*UP*CP*AP*AP*GP*GP*CP*AP*GP*UP*U)-3'), ... | 著者 | Xue, L, Chang, T, Li, Z, Zhao, H, Li, M, He, J, Chen, X, Xiong, X. | 登録日 | 2024-04-22 | 公開日 | 2024-05-29 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.79 Å) | 主引用文献 | Cryo-EM structures of Thogoto virus polymerase reveal unique RNA transcription and replication mechanisms among orthomyxoviruses. Nat Commun, 15, 2024
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8Z97
| Cryo-EM structure of Thogoto virus polymerase in a transcription elongation conformation | 分子名称: | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-(2'-O-METHYL)-ADENOSINE, Polymerase acidic protein, Polymerase basic protein 2, ... | 著者 | Xue, L, Chang, T, Li, Z, Zhao, H, Li, M, He, J, Chen, X, Xiong, X. | 登録日 | 2024-04-22 | 公開日 | 2024-05-29 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.65 Å) | 主引用文献 | Cryo-EM structures of Thogoto virus polymerase reveal unique RNA transcription and replication mechanisms among orthomyxoviruses. Nat Commun, 15, 2024
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8Z8J
| Cryo-EM structure of Thogoto virus polymerase in transcription pre-initiation conformation 2 | 分子名称: | Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(*AP*GP*AP*GP*AP*AP*AP*UP*CP*AP*AP*GP*GP*CP*AP*GP*UP*U)-3'), ... | 著者 | Xue, L, Chang, T, Li, Z, Zhao, H, Li, M, He, J, Chen, X, Xiong, X. | 登録日 | 2024-04-22 | 公開日 | 2024-05-29 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.16 Å) | 主引用文献 | Cryo-EM structures of Thogoto virus polymerase reveal unique RNA transcription and replication mechanisms among orthomyxoviruses. Nat Commun, 15, 2024
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8Z9H
| Cryo-EM structure of Thogoto virus polymerase in a transcription elongation-reception conformation | 分子名称: | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-(2'-O-METHYL)-ADENOSINE, Polymerase acidic protein, Polymerase basic protein 2, ... | 著者 | Xue, L, Chang, T, Li, Z, Zhao, H, Li, M, He, J, Chen, X, Xiong, X. | 登録日 | 2024-04-23 | 公開日 | 2024-05-29 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Cryo-EM structures of Thogoto virus polymerase reveal unique RNA transcription and replication mechanisms among orthomyxoviruses. Nat Commun, 15, 2024
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8Z85
| Cryo-EM structure of Thogoto virus polymerase in transcription pre-initiation conformation 1 | 分子名称: | Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(*AP*GP*AP*GP*AP*AP*AP*UP*CP*AP*AP*GP*GP*CP*AP*GP*UP*U)-3'), ... | 著者 | Xue, L, Chang, T, Li, Z, Zhao, H, Li, M, He, J, Chen, X, Xiong, X. | 登録日 | 2024-04-21 | 公開日 | 2024-05-29 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | Cryo-EM structures of Thogoto virus polymerase reveal unique RNA transcription and replication mechanisms among orthomyxoviruses. Nat Commun, 15, 2024
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8Z9Q
| Cryo-EM structure of Thogoto virus polymerase in a replication reception conformation | 分子名称: | Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-D(*(ATP))-R(P*GP*CP*AP*AP*AP*AP*AP*CP*A)-3'), ... | 著者 | Xue, L, Chang, T, Li, Z, Zhao, H, Li, M, He, J, Chen, X, Xiong, X. | 登録日 | 2024-04-23 | 公開日 | 2024-05-29 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.33 Å) | 主引用文献 | Cryo-EM structures of Thogoto virus polymerase reveal unique RNA transcription and replication mechanisms among orthomyxoviruses. Nat Commun, 15, 2024
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8Z8X
| Cryo-EM structure of Thogoto virus polymerase in a transcription initiation conformation | 分子名称: | PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, Polymerase acidic protein, Polymerase basic protein 2, ... | 著者 | Xue, L, Chang, T, Li, Z, Zhao, H, Li, M, He, J, Chen, X, Xiong, X. | 登録日 | 2024-04-22 | 公開日 | 2024-05-29 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.06 Å) | 主引用文献 | Cryo-EM structures of Thogoto virus polymerase reveal unique RNA transcription and replication mechanisms among orthomyxoviruses. Nat Commun, 15, 2024
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6OGZ
| In situ structure of Rotavirus RNA-dependent RNA polymerase at transcript-elongated state | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, Inner capsid protein VP2, RNA (5'-R(P*AP*UP*AP*UP*AP*UP*AP*UP*AP*UP*AP*UP*AP*UP*AP*UP*A)-3'), ... | 著者 | Ding, K, Chang, T, Shen, W, Roy, P, Zhou, Z.H. | 登録日 | 2019-04-03 | 公開日 | 2019-05-22 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | In situ structures of rotavirus polymerase in action and mechanism of mRNA transcription and release. Nat Commun, 10, 2019
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6OGY
| In situ structure of Rotavirus RNA-dependent RNA polymerase at duplex-open state | 分子名称: | DNA/RNA (5'-D(*(GTG))-R(P*GP*C)-3'), Inner capsid protein VP2, RNA (5'-R(P*AP*GP*CP*C)-3'), ... | 著者 | Ding, K, Chang, T, Shen, W, Roy, P, Zhou, Z.H. | 登録日 | 2019-04-03 | 公開日 | 2019-05-22 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | In situ structures of rotavirus polymerase in action and mechanism of mRNA transcription and release. Nat Commun, 10, 2019
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4Y4R
| Crystal structure of ribosomal oxygenase NO66 dimer mutant | 分子名称: | ACETATE ION, Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66, NICKEL (II) ION | 著者 | Wang, C, Hang, T, Zang, J. | 登録日 | 2015-02-11 | 公開日 | 2015-10-07 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structure of the JmjC domain-containing protein NO66 complexed with ribosomal protein Rpl8. Acta Crystallogr.,Sect.D, 71, 2015
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1JR9
| Crystal Structure of manganese superoxide dismutases from Bacillus halodenitrificans | 分子名称: | MANGANESE (II) ION, ZINC ION, manganese superoxide dismutase | 著者 | Liao, J, Liu, M.Y, Chang, T, Li, M, LeGall, J, Gui, L.L, Zhang, J.P, Jiang, T, Liang, D.C, Chang, W.R. | 登録日 | 2001-08-13 | 公開日 | 2002-08-14 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Three-dimensional structure of manganese superoxide dismutase from Bacillus halodenitrificans, a component of the so-called "green protein". J.Struct.Biol., 139, 2002
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8I09
| Crystal structure of serine acetyltransferase from Salmonella typhimurium complexed with butyl gallate | 分子名称: | CYSTEINE, PHOSPHATE ION, Serine acetyltransferase, ... | 著者 | Toyomoto, T, Ono, K, Shiba, T, Momitani, K, Zhang, T, Tsutsuki, H, Ishikawa, T, Hoso, K, Hamada, K, Rahman, A, Zhong, H, Akaike, T, Yamamoto, K, Matsuoka, M, Hanaoka, K, Niidome, T, Sawa, T. | 登録日 | 2023-01-10 | 公開日 | 2023-11-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Alkyl gallates inhibit serine O -acetyltransferase in bacteria and enhance susceptibility of drug-resistant Gram-negative bacteria to antibiotics. Front Microbiol, 14, 2023
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8I06
| Crystal structure of serine acetyltransferase from Salmonella typhimurium complexed with CoA | 分子名称: | COENZYME A, CYSTEINE, Serine acetyltransferase | 著者 | Toyomoto, T, Ono, K, Shiba, T, Momitani, K, Zhang, T, Tsutsuki, H, Ishikawa, T, Hoso, K, Hamada, K, Rahman, A, Zhong, H, Akaike, T, Yamamoto, K, Matsuoka, M, Hanaoka, K, Niidome, T, Sawa, T. | 登録日 | 2023-01-10 | 公開日 | 2023-11-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Alkyl gallates inhibit serine O -acetyltransferase in bacteria and enhance susceptibility of drug-resistant Gram-negative bacteria to antibiotics. Front Microbiol, 14, 2023
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8I04
| Crystal structure of serine acetyltransferase from Salmonella typhimurium complexed with serine | 分子名称: | PHOSPHATE ION, SERINE, Serine acetyltransferase | 著者 | Toyomoto, T, Ono, K, Shiba, T, Momitani, K, Zhang, T, Tsutsuki, H, Ishikawa, T, Hoso, K, Hamada, K, Rahman, A, Zhong, H, Akaike, T, Yamamoto, K, Matsuoka, M, Hanaoka, K, Niidome, T, Sawa, T. | 登録日 | 2023-01-10 | 公開日 | 2023-11-22 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Alkyl gallates inhibit serine O -acetyltransferase in bacteria and enhance susceptibility of drug-resistant Gram-negative bacteria to antibiotics. Front Microbiol, 14, 2023
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6Q0V
| Structure of DDB1-DDA1-DCAF15 complex bound to tasisulam and RBM39 | 分子名称: | DDB1- and CUL4-associated factor 15, DET1- and DDB1-associated protein 1, DNA damage-binding protein 1, ... | 著者 | Faust, T, Yoon, H, Nowak, R.P, Donovan, K.A, Li, Z, Cai, Q, Eleuteri, N.A, Zhang, T, Gray, N.S, Fischer, E.S. | 登録日 | 2019-08-02 | 公開日 | 2019-11-13 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural complementarity facilitates E7820-mediated degradation of RBM39 by DCAF15. Nat.Chem.Biol., 16, 2020
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6Q0W
| Structure of DDB1-DDA1-DCAF15 complex bound to Indisulam and RBM39 | 分子名称: | DDB1- and CUL4-associated factor 15, DET1- and DDB1-associated protein 1, DNA damage-binding protein 1, ... | 著者 | Faust, T, Yoon, H, Nowak, R.P, Donovan, K.A, Li, Z, Cai, Q, Eleuteri, N.A, Zhang, T, Gray, N.S, Fischer, E.S. | 登録日 | 2019-08-02 | 公開日 | 2019-11-13 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural complementarity facilitates E7820-mediated degradation of RBM39 by DCAF15. Nat.Chem.Biol., 16, 2020
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