8Z9H

Cryo-EM structure of Thogoto virus polymerase in a transcription elongation-reception conformation

Summary for 8Z9H

Entry DOI	10.2210/pdb8z9h/pdb
EMDB information	39862
Descriptor	Polymerase acidic protein, RNA-directed RNA polymerase catalytic subunit, Polymerase basic protein 2, ... (7 entities in total)
Functional Keywords	rna polymerase, transcription
Biological source	Thogoto virus (isolate SiAr 126) (Tho) More
Total number of polymer chains	11
Total formula weight	518837.83
Authors	Xue, L.,Chang, T.,Li, Z.,Zhao, H.,Li, M.,He, J.,Chen, X.,Xiong, X. (deposition date: 2024-04-23, release date: 2024-05-29, Last modification date: 2024-06-19)
Primary citation	Xue, L.,Chang, T.,Li, Z.,Wang, C.,Zhao, H.,Li, M.,Tang, P.,Wen, X.,Yu, M.,Wu, J.,Bao, X.,Wang, X.,Gong, P.,He, J.,Chen, X.,Xiong, X. Cryo-EM structures of Thogoto virus polymerase reveal unique RNA transcription and replication mechanisms among orthomyxoviruses. Nat Commun, 15:4620-4620, 2024 Cited by PubMed: 38816392 DOI: 10.1038/s41467-024-48848-3 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.7 Å)

Structure validation