6SI1
 
 | | p53 cancer mutant Y220H | | 分子名称: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Cellular tumor antigen p53, ... | | 著者 | Joerger, A.C, Kraemer, A, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2019-08-08 | | 公開日 | 2020-02-19 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.44 Å) | | 主引用文献 | Targeting Cavity-Creating p53 Cancer Mutations with Small-Molecule Stabilizers: the Y220X Paradigm.
Acs Chem.Biol., 15, 2020
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4TS1
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2BTH
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2BTG
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5AOM
 | | Structure of the p53 cancer mutant Y220C with bound small molecule PhiKan883 | | 分子名称: | CELLULAR TUMOR ANTIGEN P53, GLYCEROL, N-(5-chloranyl-2-oxidanyl-phenyl)piperidine-4-carboxamide, ... | | 著者 | Joerger, A.C, Boeckler, F.M, Wilcken, R. | | 登録日 | 2015-09-10 | | 公開日 | 2015-12-16 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | Exploiting Transient Protein States for the Design of Small-Molecule Stabilizers of Mutant P53.
Structure, 23, 2015
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5AOL
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5AOK
 | | Structure of the p53 cancer mutant Y220C with bound small molecule PhiKan7099 | | 分子名称: | 5-[2-cyclopropyl-5-(1H-pyrrol-1-yl)-1,3-oxazol-4-yl]-1H-1,2,3,4-tetrazole, CELLULAR TUMOR ANTIGEN P53, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Joerger, A.C. | | 登録日 | 2015-09-10 | | 公開日 | 2015-12-16 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Exploiting Transient Protein States for the Design of Small-Molecule Stabilizers of Mutant P53.
Structure, 23, 2015
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1K5R
 | | YAP65 WW domain S24-Amino-Ethylsulfanyl-Acetic Acid mutant | | 分子名称: | 65 KDA YES-ASSOCIATED PROTEIN, Fragment of WBP-1 | | 著者 | Ferguson, N, Pires, J.R, Toepert, F, Johnson, C.M, Pan, Y.P, Volkmer-Engert, R, Schneider-Mergener, J, Daggett, V, Oschkinat, H, Fersht, A.R. | | 登録日 | 2001-10-12 | | 公開日 | 2001-11-02 | | 最終更新日 | 2023-11-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Using flexible loop mimetics to extend phi-value analysis to secondary structure interactions.
Proc.Natl.Acad.Sci.USA, 98, 2001
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1UQS
 | | The Crystal Structure of Human CD1b with a Bound Bacterial Glycolipid | | 分子名称: | BETA-2-MICROGLOBULIN, GLUCOSE MONOMYCOLATE, T-CELL SURFACE GLYCOPROTEIN CD1B | | 著者 | Batuwangala, T, Shepherd, D, Gadola, S.D, Gibson, K.J.C, Zaccai, N.R, Besra, G.S, Cerundolo, V, Jones, E.Y. | | 登録日 | 2003-10-16 | | 公開日 | 2003-10-30 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | The crystal structure of human CD1b with a bound bacterial glycolipid.
J Immunol., 172, 2004
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2WQJ
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1BNS
 | | STRUCTURAL STUDIES OF BARNASE MUTANTS | | 分子名称: | BARNASE | | 著者 | Chen, Y.W. | | 登録日 | 1994-04-11 | | 公開日 | 1994-06-22 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Contribution of buried hydrogen bonds to protein stability. The crystal structures of two barnase mutants.
J.Mol.Biol., 234, 1993
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2WQI
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2WTT
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1BRH
 | | BARNASE MUTANT WITH LEU 14 REPLACED BY ALA | | 分子名称: | BARNASE, ZINC ION | | 著者 | Cramer, P.C, Buckle, A, Fersht, A. | | 登録日 | 1995-03-09 | | 公開日 | 1995-07-10 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural and energetic responses to cavity-creating mutations in hydrophobic cores: observation of a buried water molecule and the hydrophilic nature of such hydrophobic cavities.
Biochemistry, 35, 1996
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1BRK
 | | BARNASE MUTANT WITH ILE 96 REPLACED BY ALA | | 分子名称: | BARNASE, ZINC ION | | 著者 | Cramer, P.C, Buckle, A, Fersht, A. | | 登録日 | 1995-03-09 | | 公開日 | 1995-07-10 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural and energetic responses to cavity-creating mutations in hydrophobic cores: observation of a buried water molecule and the hydrophilic nature of such hydrophobic cavities.
Biochemistry, 35, 1996
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1BRJ
 | | BARNASE MUTANT WITH ILE 88 REPLACED BY ALA | | 分子名称: | BARNASE, ZINC ION | | 著者 | Cramer, P.C, Buckle, A, Fersht, A. | | 登録日 | 1995-03-09 | | 公開日 | 1995-07-10 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural and energetic responses to cavity-creating mutations in hydrophobic cores: observation of a buried water molecule and the hydrophilic nature of such hydrophobic cavities.
Biochemistry, 35, 1996
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1BRI
 | | BARNASE MUTANT WITH ILE 76 REPLACED BY ALA | | 分子名称: | BARNASE | | 著者 | Cramer, P.C, Buckle, A, Fersht, A. | | 登録日 | 1995-03-09 | | 公開日 | 1995-07-10 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural and energetic responses to cavity-creating mutations in hydrophobic cores: observation of a buried water molecule and the hydrophilic nature of such hydrophobic cavities.
Biochemistry, 35, 1996
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1CQ4
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1DXS
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1BNR
 | | BARNASE | | 分子名称: | BARNASE (G SPECIFIC ENDONUCLEASE) | | 著者 | Bycroft, M. | | 登録日 | 1995-03-31 | | 公開日 | 1995-07-31 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Determination of the three-dimensional solution structure of barnase using nuclear magnetic resonance spectroscopy.
Biochemistry, 30, 1991
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1TYP
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1SRV
 | | THERMUS THERMOPHILUS GROEL (HSP60 CLASS) FRAGMENT (APICAL DOMAIN) COMPRISING RESIDUES 192-336 | | 分子名称: | PROTEIN (GROEL (HSP60 CLASS)) | | 著者 | Walsh, M.A, Dementieva, I, Evans, G, Sanishvili, R, Joachimiak, A. | | 登録日 | 1999-03-02 | | 公開日 | 1999-03-12 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Taking MAD to the extreme: ultrafast protein structure determination.
Acta Crystallogr.,Sect.D, 55, 1999
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