8A9O
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6TFW
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![BU of 6tfw by Molmil](/molmil-images/mine/6tfw) | Crystal Structure of EGFR T790M/V948R in Complex with Covalent Pyrrolopyrimidine 18d | 分子名称: | CHLORIDE ION, Epidermal growth factor receptor, MAGNESIUM ION, ... | 著者 | Niggenaber, J, Mueller, M.P, Rauh, D. | 登録日 | 2019-11-14 | 公開日 | 2020-09-30 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Targeting Her2-insYVMA with Covalent Inhibitors-A Focused Compound Screening and Structure-Based Design Approach. J.Med.Chem., 63, 2020
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3CL6
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![BU of 3cl6 by Molmil](/molmil-images/mine/3cl6) | Crystal structure of Puue Allantoinase | 分子名称: | Puue allantoinase | 著者 | Ramazzina, I, Cendron, L, Folli, C, Berni, R, Monteverdi, D, Zanotti, G, Percudani, R. | 登録日 | 2008-03-18 | 公開日 | 2008-06-10 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | Logical identification of an allantoinase analog (puuE) recruited from polysaccharide deacetylases J.Biol.Chem., 283, 2008
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8AQ2
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![BU of 8aq2 by Molmil](/molmil-images/mine/8aq2) | In meso structure of the membrane integral lipoprotein N-acyltransferase Lnt from P. aeruginosa covalently linked with TITC | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Apolipoprotein N-acyltransferase, CITRATE ANION, ... | 著者 | Huang, C.-Y, Weichert, D, Boland, C, Smithers, L, Olieric, V, Wang, M, Caffrey, M. | 登録日 | 2022-08-11 | 公開日 | 2023-07-12 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure snapshots reveal the mechanism of a bacterial membrane lipoprotein N -acyltransferase. Sci Adv, 9, 2023
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3J2I
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![BU of 3j2i by Molmil](/molmil-images/mine/3j2i) | Structure of late pre-60S ribosomal subunits with nuclear export factor Arx1 bound at the peptide exit tunnel | 分子名称: | Eukaryotic translation initiation factor 6, Proliferation-associated protein 2G4 | 著者 | Bradatsch, B, Leidig, C, Granneman, S, Gnaedig, M, Tollervey, D, Boettcher, B, Beckmann, R, Hurt, E. | 登録日 | 2012-10-04 | 公開日 | 2012-11-07 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (11.9 Å) | 主引用文献 | Structure of the pre-60S ribosomal subunit with nuclear export factor Arx1 bound at the exit tunnel. Nat.Struct.Mol.Biol., 19, 2012
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2NLY
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![BU of 2nly by Molmil](/molmil-images/mine/2nly) | Crystal structure of protein BH1492 from Bacillus halodurans, Pfam DUF610 | 分子名称: | Divergent polysaccharide deacetylase hypothetical protein, ZINC ION | 著者 | Jin, X, Sauder, J.M, Wasserman, S, Smith, D, Burley, S.K, Shapiro, L, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2006-10-20 | 公開日 | 2006-11-07 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of hypothetical protein BH1492 from Bacillus halodurans C-125 To be Published
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8A9N
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![BU of 8a9n by Molmil](/molmil-images/mine/8a9n) | Structure of DpA polyamine acetyltransferase in complex with 1,3-DAP | 分子名称: | 1,3-DIAMINOPROPANE, Acetyltransferase, COENZYME A, ... | 著者 | Garcia-Pino, A, Jurenas, D. | 登録日 | 2022-06-28 | 公開日 | 2023-07-12 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.854 Å) | 主引用文献 | A polyamine acetyltransferase regulates the motility and biofilm formation of Acinetobacter baumannii. Nat Commun, 14, 2023
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6TGI
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![BU of 6tgi by Molmil](/molmil-images/mine/6tgi) | Crystal structure of VIM-2 in complex with triazole-based inhibitor OP24 | 分子名称: | 5-(4-chloranyl-1,5-dimethyl-pyrazol-3-yl)-4-ethyl-1,2,4-triazole-3-thiol, FORMIC ACID, Vim-1, ... | 著者 | Maso, L, Spirakis, F, Santucci, M, Simon, C, Docquier, J.D, Cruciani, G, Costi, M.P, Tondi, D, Cendron, L. | 登録日 | 2019-11-15 | 公開日 | 2020-10-14 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Virtual screening identifies broad-spectrum beta-lactamase inhibitors with activity on clinically relevant serine- and metallo-carbapenemases. Sci Rep, 10, 2020
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2NOT
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![BU of 2not by Molmil](/molmil-images/mine/2not) | NOTECHIS II-5, NEUROTOXIC PHOSPHOLIPASE A2 FROM NOTECHIS SCUTATUS SCUTATUS | 分子名称: | PHOSPHOLIPASE A2 | 著者 | Carredano, E, Westerlund, B, Persson, B, Saarinen, M, Ramaswamy, S, Eaker, D, Eklund, H. | 登録日 | 1997-03-03 | 公開日 | 1997-06-16 | 最終更新日 | 2018-04-04 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | The three-dimensional structures of two toxins from snake venom throw light on the anticoagulant and neurotoxic sites of phospholipase A2. Toxicon, 36, 1998
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2MPE
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3CKI
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![BU of 3cki by Molmil](/molmil-images/mine/3cki) | Crystal structure of the TACE-N-TIMP-3 complex | 分子名称: | ADAM 17, Metalloproteinase inhibitor 3, SODIUM ION, ... | 著者 | Wisniewska, M, Goettig, P, Maskos, K, Belouski, E, Winters, D, Hecht, R, Black, R, Bode, W. | 登録日 | 2008-03-15 | 公開日 | 2008-08-05 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural determinants of the ADAM inhibition by TIMP-3: crystal structure of the TACE-N-TIMP-3 complex. J.Mol.Biol., 381, 2008
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3ZKF
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![BU of 3zkf by Molmil](/molmil-images/mine/3zkf) | Structure of LC8 in complex with Nek9 phosphopeptide | 分子名称: | DYNEIN LIGHT CHAIN 1, CYTOPLASMIC, NEK9 PROTEIN | 著者 | Gallego, P, Velazquez-Campoy, A, Regue, L, Roig, J, Reverter, D. | 登録日 | 2013-01-22 | 公開日 | 2013-03-20 | 最終更新日 | 2013-05-15 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural Analysis of the Regulation of the Dynll/Lc8 Binding to Nek9 by Phosphorylation J.Biol.Chem., 288, 2013
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6TKG
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![BU of 6tkg by Molmil](/molmil-images/mine/6tkg) | Tsetse thrombin inhibitor in complex with human alpha-thrombin - orthorhombic form at 12keV | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Prothrombin, ... | 著者 | Calisto, B.M, Ripoll-Rozada, J, de Sanctis, D, Pereira, P.J.B. | 登録日 | 2019-11-28 | 公開日 | 2020-11-04 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Sulfotyrosine-Mediated Recognition of Human Thrombin by a Tsetse Fly Anticoagulant Mimics Physiological Substrates. Cell Chem Biol, 28, 2021
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8ATZ
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![BU of 8atz by Molmil](/molmil-images/mine/8atz) | Crystal structure of PPAR gamma (PPARG) in complex with SA112 (compound 2). | 分子名称: | 2-[4-chloranyl-6-[[3-(2-phenylethoxy)phenyl]amino]pyrimidin-2-yl]sulfanylethanoic acid, GLYCEROL, Peroxisome proliferator-activated receptor gamma | 著者 | Chaikuad, A, Arifi, S, Merk, D, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2022-08-24 | 公開日 | 2023-07-12 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Targeting the Alternative Vitamin E Metabolite Binding Site Enables Noncanonical PPAR gamma Modulation. J.Am.Chem.Soc., 145, 2023
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3CWD
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![BU of 3cwd by Molmil](/molmil-images/mine/3cwd) | Molecular recognition of nitro-fatty acids by PPAR gamma | 分子名称: | (9E,12Z)-10-nitrooctadeca-9,12-dienoic acid, (9Z,12E)-12-nitrooctadeca-9,12-dienoic acid, Peroxisome proliferator-activated receptor gamma, ... | 著者 | Martynowski, D, Li, Y. | 登録日 | 2008-04-21 | 公開日 | 2008-07-08 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Molecular recognition of nitrated fatty acids by PPAR gamma. Nat.Struct.Mol.Biol., 15, 2008
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6TC2
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![BU of 6tc2 by Molmil](/molmil-images/mine/6tc2) | Monoclinic human insulin in complex with p-coumaric acid | 分子名称: | 4'-HYDROXYCINNAMIC ACID, Insulin, PHOSPHATE ION, ... | 著者 | Triandafillidis, D.-P, Parthenios, N, Spiliopoulou, M, Valmas, A, Kosinas, C, Gozzo, F, Reinle-Schmitt, M, Beckers, D, Degen, T, Pop, M, Fitch, A, Wollenhaupt, J, Weiss, M.S, Karavassili, F, Margiolaki, I. | 登録日 | 2019-11-04 | 公開日 | 2020-11-11 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | 主引用文献 | Insulin polymorphism induced by two polyphenols: new crystal forms and advances in macromolecular powder diffraction. Acta Crystallogr D Struct Biol, 76, 2020
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2MP4
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![BU of 2mp4 by Molmil](/molmil-images/mine/2mp4) | Solution Structure of ADF like UNC-60A Protein of Caenorhabditis elegans | 分子名称: | Actin-depolymerizing factor 1, isoforms a/b | 著者 | Shukla, V, Yadav, R, Kabra, A, Kumar, D, Ono, S, Arora, A. | 登録日 | 2014-05-11 | 公開日 | 2014-06-11 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR Structure and Backbone dynamics of ADF like UNC-60A protein from Caenorhabditis elegans: its divergence from conventional ADF/cofilin To be Published
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3J6G
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![BU of 3j6g by Molmil](/molmil-images/mine/3j6g) | Minimized average structure of microtubules stabilized by taxol | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Alushin, G.M, Lander, G.C, Kellogg, E.H, Zhang, R, Baker, D, Nogales, E. | 登録日 | 2014-02-19 | 公開日 | 2014-06-04 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (5.5 Å) | 主引用文献 | High-Resolution Microtubule Structures Reveal the Structural Transitions in alpha beta-Tubulin upon GTP Hydrolysis. Cell(Cambridge,Mass.), 157, 2014
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8ATY
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![BU of 8aty by Molmil](/molmil-images/mine/8aty) | Crystal structure of PPAR gamma (PPARG) in complex with JP85 (compound 1). | 分子名称: | 2-[4-chloranyl-6-(5,6,7,8-tetrahydronaphthalen-1-ylamino)pyrimidin-2-yl]sulfanylethanoic acid, GLYCEROL, Peroxisome proliferator-activated receptor gamma | 著者 | Chaikuad, A, Pollinger, J, Merk, D, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2022-08-24 | 公開日 | 2023-07-12 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Targeting the Alternative Vitamin E Metabolite Binding Site Enables Noncanonical PPAR gamma Modulation. J.Am.Chem.Soc., 145, 2023
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6T39
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![BU of 6t39 by Molmil](/molmil-images/mine/6t39) | Crystal structure of rsEGFP2 in its off-state determined by SFX | 分子名称: | Green fluorescent protein | 著者 | Woodhouse, J, Coquelle, N, Adam, V, Barends, T.R.M, De La Mora, E, Bourgeois, D, Colletier, J.P, Schlichting, I, Weik, M. | 登録日 | 2019-10-10 | 公開日 | 2020-02-19 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Photoswitching mechanism of a fluorescent protein revealed by time-resolved crystallography and transient absorption spectroscopy. Nat Commun, 11, 2020
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1FPP
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![BU of 1fpp by Molmil](/molmil-images/mine/1fpp) | PROTEIN FARNESYLTRANSFERASE COMPLEX WITH FARNESYL DIPHOSPHATE | 分子名称: | FARNESYL DIPHOSPHATE, PHOSPHATE ION, PROTEIN FARNESYLTRANSFERASE, ... | 著者 | Dunten, P, Kammlott, U, Crowther, R, Weber, D, Palermo, R, Birktoft, J. | 登録日 | 1998-07-10 | 公開日 | 1999-06-08 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Protein farnesyltransferase: structure and implications for substrate binding. Biochemistry, 37, 1998
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2N4P
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![BU of 2n4p by Molmil](/molmil-images/mine/2n4p) | Solution structure of the n-terminal domain of tdp-43 | 分子名称: | TAR DNA-binding protein 43 | 著者 | Mompean, M, Romano, V, Pantoja-Uceda, D, Stuani, C, Baralle, F, Buratti, E, Laurents, D.V. | 登録日 | 2015-06-26 | 公開日 | 2016-01-20 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | The TDP-43 N-terminal domain structure at high resolution. Febs J., 283, 2016
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3CY1
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3ZKV
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3CYJ
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![BU of 3cyj by Molmil](/molmil-images/mine/3cyj) | Crystal structure of a mandelate racemase/muconate lactonizing enzyme-like protein from Rubrobacter xylanophilus | 分子名称: | GLYCEROL, Mandelate racemase/muconate lactonizing enzyme-like protein, SODIUM ION | 著者 | Bonanno, J.B, Freeman, J, Bain, K.T, Zhang, F, Bravo, J, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2008-04-25 | 公開日 | 2008-05-06 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of a mandelate racemase/muconate lactonizing enzyme-like protein from Rubrobacter xylanophilus. To be Published
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