4NW5
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3ZXV
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7VRM
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![BU of 7vrm by Molmil](/molmil-images/mine/7vrm) | crystal structure of BRD2-BD2 in complex with purine derivative | 分子名称: | Bromodomain-containing protein 2, THEOPHYLLINE | 著者 | Padmanabhan, B, Arole, A, Deshmukh, P, Ashok, S, Mathur, S. | 登録日 | 2021-10-23 | 公開日 | 2023-02-01 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Structural and biochemical insights into purine-based drug molecules in hBRD2 delineate a unique binding mode opening new vistas in the design of inhibitors of the BET family. Acta Crystallogr D Struct Biol, 79, 2023
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7VRQ
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![BU of 7vrq by Molmil](/molmil-images/mine/7vrq) | crystal structure of BRD2-BD2 in complex with purine derivative | 分子名称: | Bromodomain-containing protein 2, GLYCEROL, THEOBROMINE | 著者 | Padmanabhan, B, Arole, A, Deshmukh, P, Ashok, S, Mathur, S. | 登録日 | 2021-10-23 | 公開日 | 2023-02-01 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | 主引用文献 | Structural and biochemical insights into purine-based drug molecules in hBRD2 delineate a unique binding mode opening new vistas in the design of inhibitors of the BET family. Acta Crystallogr D Struct Biol, 79, 2023
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7VRO
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![BU of 7vro by Molmil](/molmil-images/mine/7vro) | crystal structure of BRD2-BD1 in complex with purine derivative | 分子名称: | Bromodomain-containing protein 2, SULFATE ION, THEOBROMINE | 著者 | Padmanabhan, B, Arole, A, Deshmukh, P, Ashok, S, Mathur, S. | 登録日 | 2021-10-23 | 公開日 | 2023-02-01 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structural and biochemical insights into purine-based drug molecules in hBRD2 delineate a unique binding mode opening new vistas in the design of inhibitors of the BET family. Acta Crystallogr D Struct Biol, 79, 2023
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7VS0
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![BU of 7vs0 by Molmil](/molmil-images/mine/7vs0) | crystal structure of BRD2-BD2 in complex with purine derivative | 分子名称: | Bromodomain-containing protein 2, Doxofylline, GLYCEROL | 著者 | Padmanabhan, B, Arole, A, Deshmukh, P, Ashok, S, Mathur, S. | 登録日 | 2021-10-25 | 公開日 | 2023-02-01 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Structural and biochemical insights into purine-based drug molecules in hBRD2 delineate a unique binding mode opening new vistas in the design of inhibitors of the BET family. Acta Crystallogr D Struct Biol, 79, 2023
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7VSF
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![BU of 7vsf by Molmil](/molmil-images/mine/7vsf) | crystal structure of BRD2-BD1 in complex with purine derivative | 分子名称: | 3-methyl-7-propyl-purine-2,6-dione, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Bromodomain-containing protein 2, ... | 著者 | Padmanabhan, B, Arole, A, Deshmukh, P, Ashok, S, Mathur, S. | 登録日 | 2021-10-26 | 公開日 | 2023-02-01 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural and biochemical insights into purine-based drug molecules in hBRD2 delineate a unique binding mode opening new vistas in the design of inhibitors of the BET family. Acta Crystallogr D Struct Biol, 79, 2023
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7VRK
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![BU of 7vrk by Molmil](/molmil-images/mine/7vrk) | crystal structure of BRD2-BD1 in complex with purine derivative | 分子名称: | Bromodomain-containing protein 2, SULFATE ION, THEOPHYLLINE | 著者 | Padmanabhan, B, Arole, A, Deshmukh, P, Ashok, S, Mathur, S. | 登録日 | 2021-10-23 | 公開日 | 2023-02-01 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | Structural and biochemical insights into purine-based drug molecules in hBRD2 delineate a unique binding mode opening new vistas in the design of inhibitors of the BET family. Acta Crystallogr D Struct Biol, 79, 2023
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7VRH
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![BU of 7vrh by Molmil](/molmil-images/mine/7vrh) | crystal structure of BRD2-BD1 in complex with guanosine analog | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 9-HYROXYETHOXYMETHYLGUANINE, Bromodomain-containing protein 2, ... | 著者 | Padmanabhan, B, Arole, A, Deshmukh, P, Ashok, S, Mathur, S. | 登録日 | 2021-10-22 | 公開日 | 2023-02-01 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural and biochemical insights into purine-based drug molecules in hBRD2 delineate a unique binding mode opening new vistas in the design of inhibitors of the BET family. Acta Crystallogr D Struct Biol, 79, 2023
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7VS1
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![BU of 7vs1 by Molmil](/molmil-images/mine/7vs1) | crystal structure of BRD2-BD2 in complex with purine derivative | 分子名称: | 3-methyl-7-propyl-purine-2,6-dione, Bromodomain-containing protein 2, GLYCEROL | 著者 | Padmanabhan, B, Arole, A, Deshmukh, P, Ashok, S, Mathur, S. | 登録日 | 2021-10-25 | 公開日 | 2023-02-01 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Structural and biochemical insights into purine-based drug molecules in hBRD2 delineate a unique binding mode opening new vistas in the design of inhibitors of the BET family. Acta Crystallogr D Struct Biol, 79, 2023
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7VRI
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![BU of 7vri by Molmil](/molmil-images/mine/7vri) | crystal structure of BRD2-BD2 in complex with guanosine analog | 分子名称: | 9-HYROXYETHOXYMETHYLGUANINE, Bromodomain-containing protein 2 | 著者 | Padmanabhan, B, Arole, A, Deshmukh, P, Ashok, S, Mathur, S. | 登録日 | 2021-10-23 | 公開日 | 2023-02-01 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural and biochemical insights into purine-based drug molecules in hBRD2 delineate a unique binding mode opening new vistas in the design of inhibitors of the BET family. Acta Crystallogr D Struct Biol, 79, 2023
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7VRZ
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![BU of 7vrz by Molmil](/molmil-images/mine/7vrz) | crystal structure of BRD2-BD1 in complex with purine derivative | 分子名称: | Bromodomain-containing protein 2, Doxofylline, SULFATE ION | 著者 | Padmanabhan, B, Arole, A, Deshmukh, P, Ashok, S, Mathur, S. | 登録日 | 2021-10-25 | 公開日 | 2023-02-01 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structural and biochemical insights into purine-based drug molecules in hBRD2 delineate a unique binding mode opening new vistas in the design of inhibitors of the BET family. Acta Crystallogr D Struct Biol, 79, 2023
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3TQV
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![BU of 3tqv by Molmil](/molmil-images/mine/3tqv) | Structure of the nicotinate-nucleotide pyrophosphorylase from Francisella tularensis. | 分子名称: | Nicotinate-nucleotide pyrophosphorylase, PHOSPHATE ION | 著者 | Rudolph, M, Cheung, J, Franklin, M, Cassidy, M, Gary, E, Burshteyn, F, Love, J. | 登録日 | 2011-09-09 | 公開日 | 2011-09-28 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | 主引用文献 | Rapid countermeasure discovery against Francisella tularensis based on a metabolic network reconstruction. Plos One, 8, 2013
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1LOU
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2PBH
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7MK1
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![BU of 7mk1 by Molmil](/molmil-images/mine/7mk1) | Structure of a protein-modified aptamer complex | 分子名称: | Antiviral innate immune response receptor RIG-I, DNA (41-MER), MAGNESIUM ION, ... | 著者 | Ren, X, Pyle, A.M. | 登録日 | 2021-04-21 | 公開日 | 2021-11-03 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Evolving A RIG-I Antagonist: A Modified DNA Aptamer Mimics Viral RNA. J.Mol.Biol., 433, 2021
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2B96
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![BU of 2b96 by Molmil](/molmil-images/mine/2b96) | Third Calcium ion found in an inhibitor bound phospholipase A2 | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-METHOXYBENZOIC ACID, CALCIUM ION, ... | 著者 | Sekar, K, Velmurugan, D, Yamane, T, Tsai, M.D. | 登録日 | 2005-10-11 | 公開日 | 2006-03-28 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Third Calcium ion found in an inhibitor bound phospholipase A2 Acta Crystallogr.,Sect.D, 62, 2006
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7LX5
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4EYC
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![BU of 4eyc by Molmil](/molmil-images/mine/4eyc) | Crystal structure of the cathelin-like domain of human cathelicidin LL-37 (hCLD) | 分子名称: | Cathelicidin antimicrobial peptide | 著者 | Pazgier, M, Pozharski, E, Toth, E, Lu, W. | 登録日 | 2012-05-01 | 公開日 | 2013-02-27 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural and Functional Analysis of the Pro-Domain of Human Cathelicidin, LL-37. Biochemistry, 52, 2013
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4N4B
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![BU of 4n4b by Molmil](/molmil-images/mine/4n4b) | Crystal Structure of the alpha-L-arabinofuranosidase PaAbf62A from Podospora anserina | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, ... | 著者 | Siguier, B, Dumon, C, Mourey, L, Tranier, S. | 登録日 | 2013-10-08 | 公開日 | 2014-01-15 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.44 Å) | 主引用文献 | First Structural Insights into alpha-L-Arabinofuranosidases from the Two GH62 Glycoside Hydrolase Subfamilies. J.Biol.Chem., 289, 2014
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4N6Z
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![BU of 4n6z by Molmil](/molmil-images/mine/4n6z) | Pim1 Complexed with a pyridylcarboxamide | 分子名称: | 3-amino-N-{4-[(3S)-3-aminopiperidin-1-yl]pyridin-3-yl}pyrazine-2-carboxamide, GLYCEROL, Serine/threonine-protein kinase pim-1 | 著者 | Bellamacina, C.R, Le, V, Shu, W, Burger, M.T, Bussiere, D. | 登録日 | 2013-10-14 | 公開日 | 2013-11-06 | 最終更新日 | 2014-07-02 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure Guided Optimization, in Vitro Activity, and in Vivo Activity of Pan-PIM Kinase Inhibitors. ACS Med Chem Lett, 4, 2013
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3ZXR
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2I4I
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![BU of 2i4i by Molmil](/molmil-images/mine/2i4i) | Crystal Structure of human DEAD-box RNA helicase DDX3X | 分子名称: | ADENOSINE MONOPHOSPHATE, ATP-dependent RNA helicase DDX3X | 著者 | Hogbom, M, Karlberg, T, Arrowsmith, C, Berglund, H, Busam, R.D, Collins, R, Edwards, A, Ehn, M, Flodin, S, Flores, A, Graslund, S, Hallberg, B.M, Hammarstrom, M, Johansson, I, Kotenyova, T, Magnusdottir, A, Nilsson-Ehle, P, Nordlund, P, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, Uppenberg, J, Van Den Berg, S, Wallden, K, Weigelt, J, Welin, M, Holmberg-Schiavone, L, Structural Genomics Consortium (SGC) | 登録日 | 2006-08-22 | 公開日 | 2006-09-05 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal Structure of Conserved Domains 1 and 2 of the Human DEAD-box Helicase DDX3X in Complex with the Mononucleotide AMP J.Mol.Biol., 372, 2007
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1ODH
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![BU of 1odh by Molmil](/molmil-images/mine/1odh) | Structure of the GCM domain bound to DNA | 分子名称: | 5'-D(*CP*GP*AP*TP*GP*CP*GP*GP*GP*TP *GP*CP*A)-3', 5'-D(*TP*GP*CP*AP*CP*CP*CP*GP*CP*AP *TP*CP*G)-3', MGCM1, ... | 著者 | Cohen, S.X, Muller, C.W. | 登録日 | 2003-02-19 | 公開日 | 2003-04-08 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Crystal Structure of the Gcm Domain-DNA Complex: A DNA-Binding Domain with a Novel Fold and Mode of Target Site Recognition Embo J., 22, 2003
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4N6Y
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![BU of 4n6y by Molmil](/molmil-images/mine/4n6y) | Pim1 Complexed with a phenylcarboxamide | 分子名称: | 2-(acetylamino)-N-[2-(piperidin-1-yl)phenyl]-1,3-thiazole-4-carboxamide, Serine/threonine-protein kinase pim-1 | 著者 | Bellamacina, C.R, Le, V, Shu, W, Burger, M.T, Bussiere, D. | 登録日 | 2013-10-14 | 公開日 | 2013-11-06 | 最終更新日 | 2014-07-02 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure Guided Optimization, in Vitro Activity, and in Vivo Activity of Pan-PIM Kinase Inhibitors. ACS Med Chem Lett, 4, 2013
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