8SJS
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![BU of 8sjs by Molmil](/molmil-images/mine/8sjs) | [3T18] Self-assembling right-handed tensegrity triangle with 18 interjunction base pairs and P63 symmetry | 分子名称: | DNA (5'-D(*CP*AP*GP*AP*GP*CP*CP*TP*GP*AP*CP*AP*TP*AP*CP*CP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*GP*CP*TP*GP*TP*GP*GP*CP*TP*C)-3'), DNA (5'-D(P*TP*CP*GP*TP*GP*GP*AP*CP*AP*GP*CP*G)-3'), ... | 著者 | Janowski, J, Vecchioni, S, Sha, R, Ohayon, Y.P. | 登録日 | 2023-04-18 | 公開日 | 2024-04-24 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (6.31 Å) | 主引用文献 | Engineering tertiary chirality in helical biopolymers. Proc.Natl.Acad.Sci.USA, 121, 2024
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8SL5
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![BU of 8sl5 by Molmil](/molmil-images/mine/8sl5) | [2T13] Self-assembling left-handed two-turn tensegrity triangle with 13 interjunction base pairs and R3 symmetry | 分子名称: | DNA (5'-D(*GP*AP*GP*CP*CP*TP*GP*AP*CP*TP*AP*CP*A)-3'), DNA (5'-D(*TP*CP*TP*GP*TP*GP*GP*C)-3'), DNA (5'-D(P*CP*GP*TP*GP*GP*AP*CP*A)-3'), ... | 著者 | Vecchioni, S, Janowski, J, Sha, R, Ohayon, Y.P. | 登録日 | 2023-04-21 | 公開日 | 2024-04-24 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (6.55 Å) | 主引用文献 | Engineering tertiary chirality in helical biopolymers. Proc.Natl.Acad.Sci.USA, 121, 2024
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8SJT
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![BU of 8sjt by Molmil](/molmil-images/mine/8sjt) | [3T14+10] Self-assembling left-handed tensegrity triangle with 14 interjunction base pairs and a 10 bp linker with R3 symmetry | 分子名称: | DNA (5'-D(*AP*CP*CP*TP*CP*CP*TP*GP*AP*GP*GP*TP*CP*GP*AP*GP*C)-3'), DNA (5'-D(*GP*AP*CP*TP*CP*TP*GP*CP*TP*A)-3'), DNA (5'-D(*GP*TP*TP*AP*GP*CP*AP*GP*AP*G)-3'), ... | 著者 | Janowski, J, Vecchioni, S, Sha, R, Ohayon, Y.P. | 登録日 | 2023-04-18 | 公開日 | 2024-04-24 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (9.38 Å) | 主引用文献 | Engineering tertiary chirality in helical biopolymers. Proc.Natl.Acad.Sci.USA, 121, 2024
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8SJV
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![BU of 8sjv by Molmil](/molmil-images/mine/8sjv) | [4T24] Self-assembling left-handed tensegrity triangle with 24 interjunction base pairs and R3 symmetry | 分子名称: | DNA (5'-D(P*CP*TP*TP*GP*TP*AP*GP*TP*CP*TP*CP*AP*CP*CP*AP*CP*TP*GP*TP*GP*AP*TP*GP*T)-3'), DNA (5'-D(P*GP*AP*AP*CP*AP*CP*TP*CP*CP*TP*GP*AP*GP*AP*CP*TP*AP*CP*AP*A)-3'), DNA (5'-D(P*GP*AP*CP*AP*TP*CP*AP*CP*AP*GP*TP*GP*GP*AP*CP*TP*AP*CP*AP*AP*G)-3'), ... | 著者 | Janowski, J, Vecchioni, S, Sha, R, Ohayon, Y.P. | 登録日 | 2023-04-18 | 公開日 | 2024-04-24 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (8.59 Å) | 主引用文献 | Engineering tertiary chirality in helical biopolymers. Proc.Natl.Acad.Sci.USA, 121, 2024
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8K4H
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![BU of 8k4h by Molmil](/molmil-images/mine/8k4h) | Crystal structure of PDE4D complexed with benzbromarone | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, ZINC ION, ... | 著者 | Liu, J.Y, Li, M.J, Xu, Y.C. | 登録日 | 2023-07-18 | 公開日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Drug repurposing and structure-based discovery of new PDE4 and PDE5 inhibitors. Eur.J.Med.Chem., 262, 2023
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8K4C
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![BU of 8k4c by Molmil](/molmil-images/mine/8k4c) | Crystal structure of PDE4D complexed with ethaverine hydrochloride | 分子名称: | 1,2-ETHANEDIOL, 1-[(3,4-diethoxyphenyl)methyl]-6,7-diethoxy-isoquinoline, MAGNESIUM ION, ... | 著者 | Liu, J.Y, Li, M.J, Xu, Y.C. | 登録日 | 2023-07-17 | 公開日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Drug repurposing and structure-based discovery of new PDE4 and PDE5 inhibitors. Eur.J.Med.Chem., 262, 2023
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8SZ5
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![BU of 8sz5 by Molmil](/molmil-images/mine/8sz5) | [2T5] Self-assembling DNA motif with 5 base pairs between junctions and P32 symmetry | 分子名称: | DNA (5'-D(*GP*AP*GP*CP*AP*GP*AP*CP*CP*TP*G)-3'), DNA (5'-D(P*AP*CP*GP*AP*CP*AP*CP*TP*CP*A)-3'), DNA (5'-D(P*CP*AP*CP*GP*T)-3'), ... | 著者 | Vecchioni, S, Janowski, J, Sha, R, Ohayon, Y.P. | 登録日 | 2023-05-26 | 公開日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | 主引用文献 | Engineering tertiary chirality in helical biopolymers. Proc.Natl.Acad.Sci.USA, 121, 2024
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7X2H
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![BU of 7x2h by Molmil](/molmil-images/mine/7x2h) | |
7XD2
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6LJS
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![BU of 6ljs by Molmil](/molmil-images/mine/6ljs) | Crystal structure of human FABP4 in complex with a novel inhibitor | 分子名称: | 1,2-ETHANEDIOL, 2-[(2-phenylphenyl)amino]benzoic acid, Fatty acid-binding protein, ... | 著者 | Su, H.X, Zhang, X.L, Li, M.J, Xu, Y.C. | 登録日 | 2019-12-17 | 公開日 | 2020-04-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Exploration of Fragment Binding Poses Leading to Efficient Discovery of Highly Potent and Orally Effective Inhibitors of FABP4 for Anti-inflammation. J.Med.Chem., 63, 2020
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6LJU
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![BU of 6lju by Molmil](/molmil-images/mine/6lju) | Crystal structure of human FABP4 in complex with a novel inhibitor | 分子名称: | 1,2-ETHANEDIOL, 2-[[3-chloranyl-4-(methylamino)-2-phenyl-phenyl]amino]benzoic acid, Fatty acid-binding protein, ... | 著者 | Su, H.X, Zhang, X.L, Li, M.J, Xu, Y.C. | 登録日 | 2019-12-17 | 公開日 | 2020-04-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Exploration of Fragment Binding Poses Leading to Efficient Discovery of Highly Potent and Orally Effective Inhibitors of FABP4 for Anti-inflammation. J.Med.Chem., 63, 2020
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6LJX
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![BU of 6ljx by Molmil](/molmil-images/mine/6ljx) | Crystal structure of human FABP4 in complex with a novel inhibitor | 分子名称: | 2-phenylazanylbenzoic acid, Fatty acid-binding protein, adipocyte | 著者 | Su, H.X, Zhang, X.L, Li, M.J, Xu, Y.C. | 登録日 | 2019-12-17 | 公開日 | 2020-04-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Exploration of Fragment Binding Poses Leading to Efficient Discovery of Highly Potent and Orally Effective Inhibitors of FABP4 for Anti-inflammation. J.Med.Chem., 63, 2020
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6LJV
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![BU of 6ljv by Molmil](/molmil-images/mine/6ljv) | Crystal structure of human FABP4 in complex with a novel inhibitor | 分子名称: | 2-[[3-chloranyl-2-(2,3-dihydro-1-benzofuran-5-yl)phenyl]amino]benzoic acid, Fatty acid-binding protein, adipocyte | 著者 | Su, H.X, Zhang, X.L, Li, M.J, Xu, Y.C. | 登録日 | 2019-12-17 | 公開日 | 2020-04-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.401 Å) | 主引用文献 | Exploration of Fragment Binding Poses Leading to Efficient Discovery of Highly Potent and Orally Effective Inhibitors of FABP4 for Anti-inflammation. J.Med.Chem., 63, 2020
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6LJW
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![BU of 6ljw by Molmil](/molmil-images/mine/6ljw) | Crystal structure of human FABP4 in complex with a novel inhibitor | 分子名称: | 1,2-ETHANEDIOL, 2-phenylazanylbenzoic acid, Fatty acid-binding protein, ... | 著者 | Su, H.X, Zhang, X.L, Li, M.J, Xu, Y.C. | 登録日 | 2019-12-17 | 公開日 | 2020-04-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Exploration of Fragment Binding Poses Leading to Efficient Discovery of Highly Potent and Orally Effective Inhibitors of FABP4 for Anti-inflammation. J.Med.Chem., 63, 2020
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6LJT
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![BU of 6ljt by Molmil](/molmil-images/mine/6ljt) | Crystal structure of human FABP4 in complex with a novel inhibitor | 分子名称: | 1,2-ETHANEDIOL, 2-[(3-chloranyl-2-phenyl-phenyl)amino]benzoic acid, Fatty acid-binding protein, ... | 著者 | Su, H.X, Zhang, X.L, Li, M.J, Xu, Y.C. | 登録日 | 2019-12-17 | 公開日 | 2020-04-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Exploration of Fragment Binding Poses Leading to Efficient Discovery of Highly Potent and Orally Effective Inhibitors of FABP4 for Anti-inflammation. J.Med.Chem., 63, 2020
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5I46
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![BU of 5i46 by Molmil](/molmil-images/mine/5i46) | Factor VIIA in complex with the inhibitor (2R,15R)-2-[(1-aminoisoquinolin-6-yl)amino]-8-fluoro-7-hydroxy-4,15,17-trimethyl-13-oxa-4,11-diazatricyclo[14.2.2.1~6,10~]henicosa-1(18),6(21),7,9,16,19-hexaene-3,12-dione | 分子名称: | (2R,15R)-2-[(1-aminoisoquinolin-6-yl)amino]-8-fluoro-7-hydroxy-4,15,17-trimethyl-13-oxa-4,11-diazatricyclo[14.2.2.1~6,10~]henicosa-1(18),6(21),7,9,16,19-hexaene-3,12-dione, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | 著者 | Wei, A. | 登録日 | 2016-02-11 | 公開日 | 2016-06-22 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | Atropisomer Control in Macrocyclic Factor VIIa Inhibitors. J.Med.Chem., 59, 2016
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4JYU
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![BU of 4jyu by Molmil](/molmil-images/mine/4jyu) | |
4JYV
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![BU of 4jyv by Molmil](/molmil-images/mine/4jyv) | |
7D4B
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![BU of 7d4b by Molmil](/molmil-images/mine/7d4b) | Crystal structure of 4-1BB in complex with a VHH | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | 著者 | Wang, C. | 登録日 | 2020-09-23 | 公開日 | 2021-07-14 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.14 Å) | 主引用文献 | Generation of a safe and efficacious llama single-domain antibody fragment (vHH) targeting the membrane-proximal region of 4-1BB for engineering therapeutic bispecific antibodies for cancer. J Immunother Cancer, 9, 2021
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7CZD
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![BU of 7czd by Molmil](/molmil-images/mine/7czd) | Crystal structure of PD-L1 in complex with a VHH | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Programmed cell death 1 ligand 1, ... | 著者 | Wang, C. | 登録日 | 2020-09-08 | 公開日 | 2021-07-14 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Generation of a safe and efficacious llama single-domain antibody fragment (vHH) targeting the membrane-proximal region of 4-1BB for engineering therapeutic bispecific antibodies for cancer. J Immunother Cancer, 9, 2021
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5VK0
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5VK1
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![BU of 5vk1 by Molmil](/molmil-images/mine/5vk1) | |
7X80
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![BU of 7x80 by Molmil](/molmil-images/mine/7x80) | |
7X7Z
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7X86
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![BU of 7x86 by Molmil](/molmil-images/mine/7x86) | The crystal structure of PloI4-F124L in complex with endo-4+2 adduct | 分子名称: | (4S,4aS,6aR,8R,9R,10aS,13S,14aS,18aR,18bR,E)-9-ethyl-4,8,19-trihydroxy-10a,12,13,18a-tetramethyl-2,3,4,4a,6a,7,8,9,10,10a,13,14,18a,18b-tetradecahydro-14a,17-(metheno)benzo[b]naphtho[2,1-h][1]azacyclododecine-16,18(1H,15H)-dione, PloI4 | 著者 | Li, M, Pan, L.F. | 登録日 | 2022-03-11 | 公開日 | 2023-02-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.303 Å) | 主引用文献 | A cyclase that catalyses competing 2 + 2 and 4 + 2 cycloadditions. Nat.Chem., 15, 2023
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