6MEP
 
 | | Crystal structure of the catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with inhibitor UNC3437 | | 分子名称: | CHLORIDE ION, MAGNESIUM ION, Tyrosine-protein kinase Mer, ... | | 著者 | Da, C, Zhang, D, Stashko, M.A, Cheng, A, Hunter, D, Norris-Drouin, J, Graves, L, Machius, M, Miley, M.J, DeRyckere, D, Earp, H.S, Graham, D.K, Frye, S.V, Wang, X, Kireev, D. | | 登録日 | 2018-09-06 | | 公開日 | 2019-09-11 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.893 Å) | | 主引用文献 | Data-Driven Construction of Antitumor Agents with Controlled Polypharmacology.
J.Am.Chem.Soc., 141, 2019
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6WZ6
 | | Complex of mutant (K173M) of Pseudomonas 7A Glutaminase-Asparaginase with L-Glu at pH 5. Covalent acyl-enzyme intermediate | | 分子名称: | 1,2-ETHANEDIOL, GLUTAMIC ACID, Glutaminase-asparaginase | | 著者 | Strzelczyk, P, Zhang, D, Wlodawer, A, Lubkowski, J. | | 登録日 | 2020-05-13 | | 公開日 | 2020-10-14 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | | 主引用文献 | Generalized enzymatic mechanism of catalysis by tetrameric L-asparaginases from mesophilic bacteria.
Sci Rep, 10, 2020
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6WYW
 | | Crystal structure of Pseudomonas 7A Glutaminase-Asparaginase in complex with L-Asp at pH 4.5 | | 分子名称: | ASPARTIC ACID, Glutaminase-asparaginase | | 著者 | Strzelczyk, P, Zhang, D, Wlodawer, A, Lubkowski, J. | | 登録日 | 2020-05-13 | | 公開日 | 2020-10-14 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | | 主引用文献 | Generalized enzymatic mechanism of catalysis by tetrameric L-asparaginases from mesophilic bacteria.
Sci Rep, 10, 2020
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6WYX
 | | Crystal structure of Pseudomonas 7A Glutaminase-Asparaginase in complex with L-Asp at pH 5.0 | | 分子名称: | ASPARTIC ACID, GLYCEROL, Glutaminase-asparaginase | | 著者 | Strzelczyk, P, Zhang, D, Wlodawer, A, Lubkowski, J. | | 登録日 | 2020-05-13 | | 公開日 | 2020-10-14 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | | 主引用文献 | Generalized enzymatic mechanism of catalysis by tetrameric L-asparaginases from mesophilic bacteria.
Sci Rep, 10, 2020
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6K7T
 | | Crystal structure of bat (Pteropus Alecto) MHC class I Ptal-N*01:01 in complex with Hendra virus-derived peptide HeV1--human beta-2 microglobulin | | 分子名称: | Beta-2-microglobulin, HeV1, MHC class I antigen | | 著者 | Lu, D, Liu, K.F, Zhang, D, Yue, C, Lu, Q, Cheng, H, Chai, Y, Qi, J.X, Gao, F.G, Liu, W.J. | | 登録日 | 2019-06-08 | | 公開日 | 2019-11-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Peptide presentation by bat MHC class I provides new insight into the antiviral immunity of bats.
Plos Biol., 17, 2019
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6K7U
 | | Crystal structure of beta-2 microglobulin (beta2m) of Bat (Pteropus Alecto) | | 分子名称: | Bat beta-2-microglobulin | | 著者 | Lu, D, Liu, K.F, Zhang, D, Yue, C, Lu, Q, Cheng, H, Chai, Y, Qi, J.X, Gao, F.G, Liu, W.J. | | 登録日 | 2019-06-08 | | 公開日 | 2019-09-18 | | 最終更新日 | 2019-12-04 | | 実験手法 | X-RAY DIFFRACTION (1.601 Å) | | 主引用文献 | Peptide presentation by bat MHC class I provides new insight into the antiviral immunity of bats.
Plos Biol., 17, 2019
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2HNG
 | | The Crystal Structure of Protein of Unknown Function SP1558 from Streptococcus pneumoniae | | 分子名称: | Hypothetical protein | | 著者 | Kim, Y, Zhang, D, Zhou, M, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2006-07-12 | | 公開日 | 2006-08-15 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | The Crystal Structure of Hypothetical Protein SP_1558 from Streptococcus pneumoniae
To be Published, 2006
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5U8T
 | | Structure of Eukaryotic CMG Helicase at a Replication Fork and Implications | | 分子名称: | Cell division control protein 45, DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DNA replication complex GINS protein PSF1, ... | | 著者 | Li, B, Georgescu, R, Yuan, Z, Santos, R, Sun, J, Zhang, D, Yurieva, O, Li, H, O'Donnell, M.E. | | 登録日 | 2016-12-15 | | 公開日 | 2017-02-08 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | | 主引用文献 | Structure of eukaryotic CMG helicase at a replication fork and implications to replisome architecture and origin initiation.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5U8S
 | | Structure of eukaryotic CMG helicase at a replication fork | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 45, DNA (26-MER), ... | | 著者 | Li, H, Li, B, Georgescu, R, Yuan, Z, Santos, R, Sun, J, Zhang, D, Yurieva, O, O'Donnell, M.E. | | 登録日 | 2016-12-14 | | 公開日 | 2017-01-25 | | 最終更新日 | 2020-01-01 | | 実験手法 | ELECTRON MICROSCOPY (6.101 Å) | | 主引用文献 | Structure of eukaryotic CMG helicase at a replication fork and implications to replisome architecture and origin initiation.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6M1H
 | | CryoEM structure of human PAC1 receptor in complex with maxadilan | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | | 著者 | Song, X, Wang, J, Zhang, D, Wang, H.W, Ma, Y. | | 登録日 | 2020-02-26 | | 公開日 | 2020-03-11 | | 最終更新日 | 2020-05-27 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Cryo-EM structures of PAC1 receptor reveal ligand binding mechanism.
Cell Res., 30, 2020
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6M1I
 | | CryoEM structure of human PAC1 receptor in complex with PACAP38 | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | | 著者 | Song, X, Wang, J, Zhang, D, Wang, H.W, Ma, Y. | | 登録日 | 2020-02-26 | | 公開日 | 2020-03-11 | | 最終更新日 | 2020-05-27 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Cryo-EM structures of PAC1 receptor reveal ligand binding mechanism.
Cell Res., 30, 2020
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6J23
 | | Crystal structure of arabidopsis ADAL complexed with GMP | | 分子名称: | Adenosine/AMP deaminase family protein, GUANOSINE-5'-MONOPHOSPHATE, ZINC ION | | 著者 | Wu, B.X, Zhang, D, Nie, H.B, Shen, S.L, Li, S.S, Patel, D.J. | | 登録日 | 2018-12-30 | | 公開日 | 2019-02-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure ofArabidopsis thaliana N6-methyl-AMP deaminase ADAL with bound GMP and IMP and implications forN6-methyl-AMP recognition and processing.
Rna Biol., 16, 2019
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6J4T
 | | Crystal structure of arabidopsis ADAL complexed with IMP | | 分子名称: | Adenosine/AMP deaminase family protein, INOSINIC ACID, ZINC ION | | 著者 | Wu, B.X, Zhang, D, Nie, H.B, Shen, S.L, Li, S.S, Patel, D.J. | | 登録日 | 2019-01-10 | | 公開日 | 2019-07-31 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Structure ofArabidopsis thaliana N6-methyl-AMP deaminase ADAL with bound GMP and IMP and implications forN6-methyl-AMP recognition and processing.
Rna Biol., 16, 2019
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6IS9
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6JRG
 | | Crystal structure of ZmMoc1 H253A mutant in complex with Holliday junction | | 分子名称: | DNA (32-MER), DNA (33-MER), MAGNESIUM ION, ... | | 著者 | Lin, Z, Lin, H, Zhang, D, Yuan, C. | | 登録日 | 2019-04-03 | | 公開日 | 2019-10-23 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.005 Å) | | 主引用文献 | Structural basis of sequence-specific Holliday junction cleavage by MOC1.
Nat.Chem.Biol., 15, 2019
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6IS8
 | | Crystal structure of ZmMoc1 D115N mutant in complex with Holliday junction | | 分子名称: | DNA (33-MER), MAGNESIUM ION, Monokaryotic chloroplast 1, ... | | 著者 | Lin, Z, Lin, H, Zhang, D, Yuan, C. | | 登録日 | 2018-11-15 | | 公開日 | 2019-10-23 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | | 主引用文献 | Structural basis of sequence-specific Holliday junction cleavage by MOC1.
Nat.Chem.Biol., 15, 2019
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6JRF
 | | Crystal structure of ZmMoc1-Holliday junction Complex in the presence of Calcium | | 分子名称: | CALCIUM ION, DNA (33-MER), Monokaryotic chloroplast 1, ... | | 著者 | Lin, Z, Lin, H, Zhang, D, Yuan, C. | | 登録日 | 2019-04-03 | | 公開日 | 2019-10-23 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.047 Å) | | 主引用文献 | Structural basis of sequence-specific Holliday junction cleavage by MOC1.
Nat.Chem.Biol., 15, 2019
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6IV5
 | | Crystal structure of arabidopsis N6-mAMP deaminase MAPDA | | 分子名称: | Adenosine/AMP deaminase family protein, PHOSPHATE ION, ZINC ION | | 著者 | Wu, B.X, Zhang, D, Nie, H.B, Shen, S.L, Li, S.S, Patel, D.J. | | 登録日 | 2018-12-02 | | 公開日 | 2019-02-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.749 Å) | | 主引用文献 | Structure ofArabidopsis thaliana N6-methyl-AMP deaminase ADAL with bound GMP and IMP and implications forN6-methyl-AMP recognition and processing.
Rna Biol., 16, 2019
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7F6H
 | | Cryo-EM structure of human bradykinin receptor BK2R in complex Gq proteins and bradykinin | | 分子名称: | Bradykinin, Bradykinin receptor BK2R, CHOLESTEROL, ... | | 著者 | Shen, J, Zhang, D, Fu, Y, Chen, A, Zhang, H. | | 登録日 | 2021-06-25 | | 公開日 | 2022-01-05 | | 最終更新日 | 2023-01-18 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Cryo-EM structures of human bradykinin receptor-G q proteins complexes.
Nat Commun, 13, 2022
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7F6I
 | | Cryo-EM structure of human bradykinin receptor BK2R in complex Gq proteins and kallidin | | 分子名称: | Bradykinin receptor BK2R, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Shen, J, Zhang, D, Fu, Y, Chen, A, Zhang, H. | | 登録日 | 2021-06-25 | | 公開日 | 2022-01-05 | | 最終更新日 | 2023-01-18 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Cryo-EM structures of human bradykinin receptor-G q proteins complexes.
Nat Commun, 13, 2022
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8HHK
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8HHI
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7XA7
 | | Crystal structure of SARS-CoV-2 receptor-binding domain in complex with intermediate horseshoe bat ACE2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme, Spike protein S1, ... | | 著者 | Tang, L.F, Zhang, D, Han, P, Qi, J.X. | | 登録日 | 2022-03-17 | | 公開日 | 2022-12-21 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.31 Å) | | 主引用文献 | Structural basis of SARS-CoV-2 and its variants binding to intermediate horseshoe bat ACE2.
Int J Biol Sci, 18, 2022
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2LZ5
 | | Solution structure of a Novel Alpha-Conotoxin TxIB | | 分子名称: | Conotoxin_TxIB | | 著者 | Luo, S, Zhangsun, D, Wu, Y, Zhu, X, Hu, Y, McIntyre, M, Christensen, S, Akcan, M, Craik, D, McIntosh, J. | | 登録日 | 2012-09-23 | | 公開日 | 2012-12-05 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Characterization of a novel alpha-conotoxin from conus textile that selectively targets alpha6/alpha3beta2beta3 nicotinic acetylcholine receptors.
J.Biol.Chem., 288, 2013
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2M3I
 | | Characterization of a Novel Alpha4/6-Conotoxin TxIC from Conus textile that Potently Blocks alpha3beta4 Nicotinic Acetylcholine Receptors | | 分子名称: | Alpha-conotoxin | | 著者 | Luo, S, Zhangsun, D, Zhu, X, Wu, Y, Hu, Y, Christensen, S, Akcan, M, Craik, D.J, McIntosh, J.M. | | 登録日 | 2013-01-20 | | 公開日 | 2013-12-04 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Characterization of a Novel alpha-Conotoxin TxID from Conus textile That Potently Blocks Rat alpha 3 beta 4 Nicotinic Acetylcholine Receptors.
J.Med.Chem., 56, 2013
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