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5HXQ
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BU of 5hxq by Molmil
Crystal Structure of Z,Z-Farnesyl Diphosphate Synthase (D71M, E75A and H103Y Mutants) Complexed with DMSPP
分子名称: (2Z,6Z)-farnesyl diphosphate synthase, chloroplastic, 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, ...
著者Lee, C.C, Chan, Y.T, Wang, A.H.J.
登録日2016-01-31
公開日2017-04-05
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal Structure and Potential Head-to-Middle Condensation Function of a Z,Z-Farnesyl Diphosphate Synthase
Acs Omega, 2, 2017
5ITM
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BU of 5itm by Molmil
The structure of truncated histone-like protein
分子名称: AbrB family transcriptional regulator
著者Lin, B.L, Chen, C.Y, Huang, C.H, Ko, T.P, Chiang, C.H, Lin, K.F, Chang, Y.C, Lin, P.Y, Tsai, H.H.G, Wang, A.H.J.
登録日2016-03-17
公開日2017-01-25
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献The Arginine Pairs and C-Termini of the Sso7c4 from Sulfolobus solfataricus Participate in Binding and Bending DNA.
PLoS ONE, 12, 2017
5ITJ
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BU of 5itj by Molmil
The structure of histone-like protein
分子名称: AbrB family transcriptional regulator, SULFATE ION, TETRAETHYLENE GLYCOL
著者Lin, B.L, Chen, C.Y, Huang, C.H, Ko, T.P, Chiang, C.H, Lin, K.F, Chang, Y.C, Lin, P.Y, Tsai, H.H.G, Wang, A.H.J.
登録日2016-03-17
公開日2017-01-25
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献The Arginine Pairs and C-Termini of the Sso7c4 from Sulfolobus solfataricus Participate in Binding and Bending DNA.
PLoS ONE, 12, 2017
7C8T
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BU of 7c8t by Molmil
Complex Structure of SARS-CoV-2 3CL Protease with TG-0205221
分子名称: 3C-like proteinase, N-[(BENZYLOXY)CARBONYL]-O-(TERT-BUTYL)-L-THREONYL-3-CYCLOHEXYL-N-[(1S)-2-HYDROXY-1-{[(3S)-2-OXOPYRROLIDIN-3-YL]METHYL}ETHYL]-L-ALANINAMIDE
著者Lee, C.C, Wang, A.H.J, Kuo, C.J, Liang, P.H.
登録日2020-06-03
公開日2020-06-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Complex Structures and Cellular Activities of the Potent SARS-CoV-2 3CLpro Inhibitors Guiding Drug Discovery Against COVID-19
To Be Published
7C8R
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BU of 7c8r by Molmil
Complex Structure of SARS-CoV-2 3CL Protease with TG-0203770
分子名称: 3C-like proteinase, ethyl (4R)-4-[[(2S)-4-methyl-2-[[(2S,3R)-3-[(2-methylpropan-2-yl)oxy]-2-(phenylmethoxycarbonylamino)butanoyl]amino]pentanoyl]amino]-5-[(3S)-2-oxidanylidenepyrrolidin-3-yl]pentanoate
著者Lee, C.C, Wang, A.H.J, Kuo, C.J, Liang, P.H.
登録日2020-06-03
公開日2020-06-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Complex Structures and Cellular Activities of the Potent SARS-CoV-2 3CLpro Inhibitors Guiding Drug Discovery Against COVID-19
To Be Published
7CGA
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BU of 7cga by Molmil
Crystal structure of human unphosphorylated p38gamma
分子名称: Mitogen-activated protein kinase 12
著者Lee, C.C, Hsu, S.F, Chen, K.E, Wang, A.H.J, Meng, T.C.
登録日2020-06-30
公開日2021-06-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Structural basis for allosteric regulation of protein tyrosine phosphatase PTPN3 by unphosphorylated MAP kinase p38g
To be published
3VJC
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BU of 3vjc by Molmil
Crystal structure of the human squalene synthase in complex with zaragozic acid A
分子名称: MAGNESIUM ION, PHOSPHATE ION, Squalene synthase, ...
著者Liu, C.I, Jeng, W.Y, Chang, W.J, Ko, T.P, Wang, A.H.J.
登録日2011-10-14
公開日2012-04-11
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Binding modes of zaragozic acid A to human squalene synthase and staphylococcal dehydrosqualene synthase
J.Biol.Chem., 287, 2012
3VJ9
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BU of 3vj9 by Molmil
Crystal structure of the human squalene synthase
分子名称: CALCIUM ION, NICKEL (II) ION, Squalene synthase
著者Liu, C.I, Jeng, W.Y, Chang, W.J, Wang, A.H.J.
登録日2011-10-14
公開日2012-04-11
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Binding modes of zaragozic acid A to human squalene synthase and staphylococcal dehydrosqualene synthase
J.Biol.Chem., 287, 2012
3VJA
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BU of 3vja by Molmil
Crystal structure of the human squalene synthase
分子名称: NICKEL (II) ION, Squalene synthase
著者Liu, C.I, Jeng, W.Y, Chang, W.J, Wang, A.H.J.
登録日2011-10-14
公開日2012-04-11
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Binding modes of zaragozic acid A to human squalene synthase and staphylococcal dehydrosqualene synthase
J.Biol.Chem., 287, 2012
3VJB
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BU of 3vjb by Molmil
Crystal structure of the human squalene synthase
分子名称: Squalene synthase
著者Liu, C.I, Jeng, W.Y, Chang, W.J, Wang, A.H.J.
登録日2011-10-14
公開日2012-04-11
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Binding modes of zaragozic acid A to human squalene synthase and staphylococcal dehydrosqualene synthase
J.Biol.Chem., 287, 2012
3VJ8
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BU of 3vj8 by Molmil
Crystal structure of the human squalene synthase
分子名称: Squalene synthase
著者Liu, C.I, Jeng, W.Y, Chang, W.J, Wang, A.H.J.
登録日2011-10-14
公開日2012-04-11
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Binding modes of zaragozic acid A to human squalene synthase and staphylococcal dehydrosqualene synthase
J.Biol.Chem., 287, 2012
3W9D
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BU of 3w9d by Molmil
Structure of Human Monoclonal Antibody E317 Fab
分子名称: Antibody Fab heavy chain, Antibody Fab light chain
著者Lee, C.C, Lin, L.L, Wang, A.H.J.
登録日2013-04-03
公開日2013-10-02
最終更新日2021-04-28
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Structural basis for the antibody neutralization of herpes simplex virus
Acta Crystallogr.,Sect.D, 69, 2013
3W9E
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BU of 3w9e by Molmil
Structure of Human Monoclonal Antibody E317 Fab Complex with HSV-2 gD
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab heavy chain, Antibody Fab light chain, ...
著者Lee, C.C, Lin, L.L, Wang, A.H.J.
登録日2013-04-03
公開日2013-10-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for the antibody neutralization of herpes simplex virus
Acta Crystallogr.,Sect.D, 69, 2013
3WEH
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BU of 3weh by Molmil
Crystal structure of the human squalene synthase in complex with presqualene pyrophosphate
分子名称: MAGNESIUM ION, Squalene synthase, {(1R,2R,3R)-2-[(3E)-4,8-dimethylnona-3,7-dien-1-yl]-2-methyl-3-[(1E,5E)-2,6,10-trimethylundeca-1,5,9-trien-1-yl]cyclopropyl}methyl trihydrogen diphosphate
著者Liu, C.I, Jeng, W.Y, Wang, A.H.J.
登録日2013-07-07
公開日2014-02-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Structural insights into the catalytic mechanism of human squalene synthase.
Acta Crystallogr.,Sect.D, 70, 2014
5Z1X
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BU of 5z1x by Molmil
Crystal Structure of Laccase from Cerrena sp. RSD1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (II) ION, ...
著者Lee, C.C, Wu, M.H, Ho, T.H, Wang, A.H.J.
登録日2017-12-28
公開日2018-09-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.38 Å)
主引用文献Kinetic analysis and structural studies of a high-efficiency laccase fromCerrenasp. RSD1.
FEBS Open Bio, 8, 2018
5Z22
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BU of 5z22 by Molmil
Crystal Structure of Laccase from Cerrena sp. RSD1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COPPER (II) ION, ...
著者Lee, C.C, Wu, M.H, Ho, T.H, Wang, A.H.J.
登録日2017-12-28
公開日2019-01-30
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Enhancement of laccase activity by pre-incubation with organic solvents.
Sci Rep, 9, 2019
8IKR
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BU of 8ikr by Molmil
Crystal structure of DpaA
分子名称: YkuD domain-containing protein
著者Wang, H.-J, Hsieh, K.-Y, Lee, S.-H, Chang, C.-I.
登録日2023-03-01
公開日2023-10-11
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis for the hydrolytic activity of the transpeptidase-like protein DpaA to detach Braun's lipoprotein from peptidoglycan.
Mbio, 14, 2023
2MXD
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BU of 2mxd by Molmil
Solution structure of VPg of porcine sapovirus
分子名称: Viral protein genome-linked
著者Kim, J, Hwang, H, Min, H, Yun, H, Cho, K, Pelton, J.G, Wemmer, D.E, Lee, C.
登録日2014-12-24
公開日2015-04-15
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure of the porcine sapovirus VPg core reveals a stable three-helical bundle with a conserved surface patch.
Biochem.Biophys.Res.Commun., 459, 2015
4QI1
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BU of 4qi1 by Molmil
Crystal structure of H. walsbyi bacteriorhodopsin
分子名称: Bacteriorhodopsin-I, GLYCEROL, RETINAL, ...
著者Wang, A.H.J, Hsu, M.F, Yang, C.S, Fu, H.Y.
登録日2014-05-30
公開日2015-07-29
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural and Functional Studies of a Newly Grouped Haloquadratum walsbyi Bacteriorhodopsin Reveal the Acid-resistant Light-driven Proton Pumping Activity.
J. Biol. Chem., 290, 2015
5X0I
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BU of 5x0i by Molmil
Crystal structure of PKM2 R399E mutant complexed with FBP and serine
分子名称: 1,6-di-O-phosphono-beta-D-fructofuranose, MAGNESIUM ION, POTASSIUM ION, ...
著者Wang, W.C, Chen, T.J.
登録日2017-01-20
公開日2018-01-31
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Mutations in the PKM2 exon-10 region are associated with reduced allostery and increased nuclear translocation.
Commun Biol, 2, 2019
4YJ5
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BU of 4yj5 by Molmil
Crystal structure of PKM2 mutant
分子名称: 1,6-di-O-phosphono-beta-D-fructofuranose, MAGNESIUM ION, PYRUVIC ACID, ...
著者Liu, J.-S, Wu, C.-W, Wang, W.-C.
登録日2015-03-03
公開日2016-03-09
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Mutations in the PKM2 exon-10 region are associated with reduced allostery and increased nuclear translocation
Commun Biol, 2, 2019
3MRS
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BU of 3mrs by Molmil
Crystal structure of shikimate kinase mutant (R57A) from Helicobacter pylori
分子名称: Shikimate kinase
著者Cheng, W.C, Chen, T.J, Lin, S.C, Wang, W.C.
登録日2010-04-29
公開日2011-05-04
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structures of Helicobacter pylori shikimate kinase reveal a selective inhibitor-induced-fit mechanism
Plos One, 7, 2012
4ZB1
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BU of 4zb1 by Molmil
Crystal Structure of Blue Chromoprotein sgBP from Stichodactyla Gigantea
分子名称: 2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL, Blue chromoprotein, sgBP
著者Lee, C.C, Ching, C.Y, Tsai, H.J, Wang, A.H.J.
登録日2015-04-14
公開日2015-08-12
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Chromophore Deprotonation State Alters the Optical Properties of Blue Chromoprotein
Plos One, 10, 2015
5GXY
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BU of 5gxy by Molmil
Crystal structure of endoglucanase CelQ from Clostridium thermocellum complexed with cellobiose and Tris
分子名称: 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BROMIDE ION, ...
著者Jeng, W.Y, Liu, C.I, Wang, A.H.J.
登録日2016-09-21
公開日2017-09-27
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal Structures of the C-Terminally Truncated Endoglucanase Cel9Q from Clostridium thermocellum Complexed with Cellodextrins and Tris.
Chembiochem, 20, 2019
5GY0
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BU of 5gy0 by Molmil
Crystal structure of endoglucanase CelQ from Clostridium thermocellum complexed with cellotetraose
分子名称: BROMIDE ION, CALCIUM ION, CHLORIDE ION, ...
著者Jeng, W.Y, Liu, C.I, Wang, A.H.J.
登録日2016-09-21
公開日2017-09-27
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Crystal Structures of the C-Terminally Truncated Endoglucanase Cel9Q from Clostridium thermocellum Complexed with Cellodextrins and Tris.
Chembiochem, 20, 2019

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