7UC2
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2FQ3
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![BU of 2fq3 by Molmil](/molmil-images/mine/2fq3) | Structure and function of the SWIRM domain, a conserved protein module found in chromatin regulatory complexes | 分子名称: | Transcription regulatory protein SWI3 | 著者 | Da, G, Lenkart, J, Zhao, K, Shiekhattar, R, Cairns, B.R, Marmorstein, R. | 登録日 | 2006-01-17 | 公開日 | 2006-02-07 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Structure and function of the SWIRM domain, a conserved protein module found in chromatin regulatory complexes Proc.Natl.Acad.Sci.Usa, 103, 2006
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1CM0
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![BU of 1cm0 by Molmil](/molmil-images/mine/1cm0) | CRYSTAL STRUCTURE OF THE PCAF/COENZYME-A COMPLEX | 分子名称: | COENZYME A, P300/CBP ASSOCIATING FACTOR | 著者 | Clements, A, Rojas, J.R, Trievel, R.C, Wang, L, Berger, S.L, Marmorstein, R. | 登録日 | 1999-05-12 | 公開日 | 1999-07-06 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of the histone acetyltransferase domain of the human PCAF transcriptional regulator bound to coenzyme A. EMBO J., 18, 1999
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1CS3
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1FY7
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![BU of 1fy7 by Molmil](/molmil-images/mine/1fy7) | CRYSTAL STRUCTURE OF YEAST ESA1 HISTONE ACETYLTRANSFERASE DOMAIN COMPLEXED WITH COENZYME A | 分子名称: | COENZYME A, ESA1 HISTONE ACETYLTRANSFERASE, SODIUM ION | 著者 | Yan, Y, Barlev, N.A, Haley, R.H, Berger, S.L, Marmorstein, R. | 登録日 | 2000-09-28 | 公開日 | 2000-11-29 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of yeast Esa1 suggests a unified mechanism for catalysis and substrate binding by histone acetyltransferases. Mol.Cell, 6, 2000
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1DUX
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![BU of 1dux by Molmil](/molmil-images/mine/1dux) | ELK-1/DNA STRUCTURE REVEALS HOW RESIDUES DISTAL FROM DNA-BINDING SURFACE AFFECT DNA-RECOGNITION | 分子名称: | DNA (5'-D(*AP*CP*AP*CP*TP*TP*CP*CP*GP*GP*TP*CP*A)-3'), DNA (5'-D(*TP*GP*AP*CP*CP*GP*GP*AP*AP*GP*TP*GP*T)-3'), ETS-DOMAIN PROTEIN ELK-1 | 著者 | Mo, Y, Vaessen, B, Johnston, K, Marmorstein, R. | 登録日 | 2000-01-19 | 公開日 | 2000-04-17 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure of the elk-1-DNA complex reveals how DNA-distal residues affect ETS domain recognition of DNA. Nat.Struct.Biol., 7, 2000
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4K2J
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4LX9
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7L1K
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1QSN
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![BU of 1qsn by Molmil](/molmil-images/mine/1qsn) | CRYSTAL STRUCTURE OF TETRAHYMENA GCN5 WITH BOUND COENZYME A AND HISTONE H3 PEPTIDE | 分子名称: | COENZYME A, HISTONE H3, TGCN5 HISTONE ACETYL TRANSFERASE | 著者 | Rojas, J.R, Trievel, R.C, Zhou, J, Mo, Y, Li, X, Berger, S.L, David Allis, C, Marmorstein, R. | 登録日 | 1999-06-22 | 公開日 | 1999-09-08 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of Tetrahymena GCN5 bound to coenzyme A and a histone H3 peptide. Nature, 401, 1999
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1S5P
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![BU of 1s5p by Molmil](/molmil-images/mine/1s5p) | Structure and substrate binding properties of cobB, a Sir2 homolog protein deacetylase from Eschericia coli. | 分子名称: | HISTONE H4 (RESIDUES 12-19), NAD-dependent deacetylase, ZINC ION | 著者 | Zhao, K, Chai, X, Marmorstein, R. | 登録日 | 2004-01-21 | 公開日 | 2004-03-23 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Structure and Substrate Binding Properties of cobB, a Sir2 Homolog Protein Deacetylase from Eschericia coli. J.Mol.Biol., 337, 2004
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1Q17
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![BU of 1q17 by Molmil](/molmil-images/mine/1q17) | Structure of the yeast Hst2 protein deacetylase in ternary complex with 2'-O-acetyl ADP ribose and histone peptide | 分子名称: | ADENOSINE-5-DIPHOSPHORIBOSE, CHLORIDE ION, HST2 protein, ... | 著者 | Zhao, K, Chai, X, Marmorstein, R. | 登録日 | 2003-07-18 | 公開日 | 2003-11-18 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structure of the Yeast Hst2 Protein Deacetylase in Ternary Complex with 2'-O-Acetyl
ADP Ribose and Histone Peptide. Structure, 11, 2003
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4RLP
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![BU of 4rlp by Molmil](/molmil-images/mine/4rlp) | Human p70s6k1 with ruthenium-based inhibitor FL772 | 分子名称: | CHLORIDE ION, [(amino-kappaN)methanethiolato](3-fluoro-9-methoxypyrido[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H,12H)-dionato-kappa~2~N,N')(N-methyl-1,4,7-trithiecan-9-amine-kappa~3~S~1~,S~4~,S~7~)ruthenium, p70S6K1 | 著者 | Domsic, J.F, Barber-Rotenberg, J, Salami, J, Qin, J, Marmorstein, R. | 登録日 | 2014-10-17 | 公開日 | 2015-01-21 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | 主引用文献 | Development of Organometallic S6K1 Inhibitors. J.Med.Chem., 58, 2015
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3TOA
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![BU of 3toa by Molmil](/molmil-images/mine/3toa) | Human MOF crystal structure with active site lysine partially acetylated | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, ZINC ION, ... | 著者 | Yuan, H, Ding, E.C, Marmorstein, R. | 登録日 | 2011-09-04 | 公開日 | 2011-11-09 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (3.004 Å) | 主引用文献 | MYST protein acetyltransferase activity requires active site lysine autoacetylation. Embo J., 31, 2011
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4RLO
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![BU of 4rlo by Molmil](/molmil-images/mine/4rlo) | Human p70s6k1 with ruthenium-based inhibitor EM5 | 分子名称: | CHLORIDE ION, DIMETHYL SULFOXIDE, GLYCEROL, ... | 著者 | Domsic, J.F, Barber-Rotenberg, J, Salami, J, Qin, J, Marmorstein, R. | 登録日 | 2014-10-17 | 公開日 | 2015-01-21 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.527 Å) | 主引用文献 | Development of Organometallic S6K1 Inhibitors. J.Med.Chem., 58, 2015
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3TO6
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1Q1A
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![BU of 1q1a by Molmil](/molmil-images/mine/1q1a) | Structure of the yeast Hst2 protein deacetylase in ternary complex with 2'-O-acetyl ADP ribose and histone peptide | 分子名称: | 2'-O-ACETYL ADENOSINE-5-DIPHOSPHORIBOSE, HST2 protein, Histone H4, ... | 著者 | Zhao, K, Chai, X, Marmorstein, R. | 登録日 | 2003-07-18 | 公開日 | 2003-11-18 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structure of the yeast Hst2 protein deacetylase in ternary complex with 2'-O-Acetyl ADP ribose and histone peptide. Structure, 11, 2003
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3TO7
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![BU of 3to7 by Molmil](/molmil-images/mine/3to7) | Crystal structure of yeast Esa1 HAT domain bound to coenzyme A with active site lysine acetylated | 分子名称: | CACODYLIC ACID, COENZYME A, GLYCEROL, ... | 著者 | Yuan, H, Ding, E.C, Marmorstein, R. | 登録日 | 2011-09-04 | 公開日 | 2011-11-09 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | MYST protein acetyltransferase activity requires active site lysine autoacetylation. Embo J., 31, 2011
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3TOB
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3TO9
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![BU of 3to9 by Molmil](/molmil-images/mine/3to9) | Crystal structure of yeast Esa1 E338Q HAT domain bound to coenzyme A with active site lysine acetylated | 分子名称: | 1,2-ETHANEDIOL, CACODYLIC ACID, COENZYME A, ... | 著者 | Yuan, H, Ding, E.C, Marmorstein, R. | 登録日 | 2011-09-04 | 公開日 | 2011-11-09 | 最終更新日 | 2012-01-18 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | MYST protein acetyltransferase activity requires active site lysine autoacetylation. Embo J., 31, 2011
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2GEQ
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![BU of 2geq by Molmil](/molmil-images/mine/2geq) | Crystal Structure of a p53 Core Dimer Bound to DNA | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5'-D(*GP*CP*GP*TP*GP*AP*GP*CP*AP*TP*GP*CP*TP*CP*AP*C)-3', Cellular tumor antigen p53, ... | 著者 | Ho, W.C, Fitzgerald, M.X, Marmorstein, R. | 登録日 | 2006-03-20 | 公開日 | 2006-05-23 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of the p53 Core Domain Dimer Bound to DNA. J.Biol.Chem., 281, 2006
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2IOO
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![BU of 2ioo by Molmil](/molmil-images/mine/2ioo) | Crystal structure of the mouse p53 core domain | 分子名称: | Cellular tumor antigen p53, ZINC ION | 著者 | Ho, W.C, Luo, C, Zhao, K, Chai, X, Fitzgerald, M.X, Marmorstein, R. | 登録日 | 2006-10-10 | 公開日 | 2006-12-05 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | High-resolution structure of the p53 core domain: implications for binding small-molecule stabilizing compounds. Acta Crystallogr.,Sect.D, 62, 2006
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2IOI
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![BU of 2ioi by Molmil](/molmil-images/mine/2ioi) | Crystal structure of the mouse p53 core domain at 1.55 A | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Cellular tumor antigen p53, ZINC ION | 著者 | Ho, W.C, Luo, C, Zhao, K, Chai, X, Fitzgerald, M.X, Marmorstein, R. | 登録日 | 2006-10-10 | 公開日 | 2006-12-05 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | High-resolution structure of the p53 core domain: implications for binding small-molecule stabilizing compounds. Acta Crystallogr.,Sect.D, 62, 2006
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2IOM
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![BU of 2iom by Molmil](/molmil-images/mine/2iom) | Mouse p53 core domain soaked with 2-propanol | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Cellular tumor antigen p53, ISOPROPYL ALCOHOL, ... | 著者 | Ho, W.C, Luo, C, Zhao, K, Chai, X, Fitzgerald, M.X, Marmorstein, R. | 登録日 | 2006-10-10 | 公開日 | 2006-12-05 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | High-resolution structure of the p53 core domain: implications for binding small-molecule stabilizing compounds. ACTA CRYSTALLOGR.,SECT.D, 62, 2006
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3CO7
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![BU of 3co7 by Molmil](/molmil-images/mine/3co7) | Crystal Structure of FoxO1 DBD Bound to DBE2 DNA | 分子名称: | DNA (5'-D(*DCP*DAP*DAP*DAP*DAP*DTP*DGP*DTP*DAP*DAP*DAP*DCP*DAP*DAP*DGP*DA)-3'), DNA (5'-D(*DTP*DCP*DTP*DTP*DGP*DTP*DTP*DTP*DAP*DCP*DAP*DTP*DTP*DTP*DTP*DG)-3'), Forkhead box protein O1 | 著者 | Brent, M.M, Anand, R, Marmorstein, R. | 登録日 | 2008-03-27 | 公開日 | 2008-09-16 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | 主引用文献 | Structural Basis for DNA Recognition by FoxO1 and Its Regulation by Posttranslational Modification. Structure, 16, 2008
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