7C8X
 
 | | Blasnase-T13A with L-asn | | 分子名称: | ASPARAGINE, Asparaginase, FORMIC ACID, ... | | 著者 | Lu, F, Ran, T, Jiao, L, Wang, W. | | 登録日 | 2020-06-03 | | 公開日 | 2021-06-09 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.994 Å) | | 主引用文献 | Structures of l-asparaginase from Bacillus licheniformis Reveal an Essential Residue for its Substrate Stereoselectivity.
J.Agric.Food Chem., 69, 2021
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8JNX
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8GRR
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8GSP
 | | Complex of FMDV A/WH/CHA/09 and bovine neutralizing scFv antibody W2 | | 分子名称: | A/WH/CHA/09 VP1, A/WH/CHA/09 VP2, A/WH/CHA/09 VP3, ... | | 著者 | He, Y, Li, K. | | 登録日 | 2022-09-06 | | 公開日 | 2023-10-11 | | 最終更新日 | 2023-12-06 | | 実験手法 | ELECTRON MICROSCOPY (3.75 Å) | | 主引用文献 | Conserved antigen structures and antibody-driven variations on foot-and-mouth disease virus serotype A revealed by bovine neutralizing monoclonal antibodies.
Plos Pathog., 19, 2023
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7ZKR
 | | Human GABARAP in complex with stapled peptide Pen3-ortho | | 分子名称: | CHLORIDE ION, Gamma-aminobutyric acid receptor-associated protein, ORTHO-XYLENE, ... | | 著者 | Ueffing, A, Brown, H, Willbold, D, Kritzer, J.A, Weiergraeber, O.H. | | 登録日 | 2022-04-13 | | 公開日 | 2022-08-31 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Structure-Based Design of Stapled Peptides That Bind GABARAP and Inhibit Autophagy.
J.Am.Chem.Soc., 144, 2022
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7ZL7
 | | Human GABARAP in complex with stapled peptide Pen8-ortho | | 分子名称: | CHLORIDE ION, Gamma-aminobutyric acid receptor-associated protein, ORTHO-XYLENE, ... | | 著者 | Ueffing, A, Brown, H, Willbold, D, Kritzer, J.A, Weiergraeber, O.H. | | 登録日 | 2022-04-14 | | 公開日 | 2022-08-31 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Structure-Based Design of Stapled Peptides That Bind GABARAP and Inhibit Autophagy.
J.Am.Chem.Soc., 144, 2022
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7DEO
 | | Crystal structure of SARS-CoV-2 RBD in complex with a neutralizing antibody scFv | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Spike protein S1, ... | | 著者 | Fu, D, Zhang, G, Li, X, Rao, Z, Guo, Y. | | 登録日 | 2020-11-04 | | 公開日 | 2021-03-31 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural basis for SARS-CoV-2 neutralizing antibodies with novel binding epitopes.
Plos Biol., 19, 2021
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7DET
 | | Crystal structure of SARS-CoV-2 RBD in complex with a neutralizing antibody scFv | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody scFv | | 著者 | Wang, Y, Zhang, G, Li, X, Rao, Z, Guo, Y. | | 登録日 | 2020-11-05 | | 公開日 | 2021-03-31 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural basis for SARS-CoV-2 neutralizing antibodies with novel binding epitopes.
Plos Biol., 19, 2021
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6AGY
 | | Aspergillus fumigatus Af293 NDK | | 分子名称: | Nucleoside diphosphate kinase | | 著者 | Hu, Y, Han, L. | | 登録日 | 2018-08-15 | | 公開日 | 2019-03-13 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Characterization of crystal structure and key residues of Aspergillus fumigatus nucleoside diphosphate kinase.
Biochem. Biophys. Res. Commun., 511, 2019
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7FEJ
 | | Complex of FMDV A/AF/72 and bovine neutralizing scFv antibody R55 | | 分子名称: | A/AF/72 VP1, A/AF/72 VP2, A/AF/72 VP3, ... | | 著者 | He, Y, Li, K, Lou, Z. | | 登録日 | 2021-07-20 | | 公開日 | 2021-09-29 | | 最終更新日 | 2022-02-16 | | 実験手法 | ELECTRON MICROSCOPY (3.91 Å) | | 主引用文献 | Structures of Foot-and-Mouth Disease Virus with Bovine Neutralizing Antibodies Reveal the Determinant of Intraserotype Cross-Neutralization.
J.Virol., 95, 2021
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7FEI
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7C91
 | | Blasnase-T13A with D-asn | | 分子名称: | D-ASPARAGINE, FORMIC ACID, L-asparaginase, ... | | 著者 | Lu, F, Ran, T, Jiao, L, Wang, W. | | 登録日 | 2020-06-04 | | 公開日 | 2021-06-09 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Structures of l-asparaginase from Bacillus licheniformis Reveal an Essential Residue for its Substrate Stereoselectivity.
J.Agric.Food Chem., 69, 2021
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7CBU
 | | Blasnase-T13A with L-Asp | | 分子名称: | ASPARTIC ACID, FORMIC ACID, L-asparaginase, ... | | 著者 | Lu, F, Ran, T, Jiao, L, Wang, W. | | 登録日 | 2020-06-14 | | 公開日 | 2021-06-09 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structures of l-asparaginase from Bacillus licheniformis Reveal an Essential Residue for its Substrate Stereoselectivity.
J.Agric.Food Chem., 69, 2021
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7CB4
 | | Crystal structures of of BlAsnase | | 分子名称: | FORMIC ACID, GLYCEROL, L-asparaginase, ... | | 著者 | Lu, F, Ran, T, Jiao, L, Wang, W. | | 登録日 | 2020-06-10 | | 公開日 | 2021-06-09 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | Structures of l-asparaginase from Bacillus licheniformis Reveal an Essential Residue for its Substrate Stereoselectivity.
J.Agric.Food Chem., 69, 2021
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7C8Q
 | | Blasnase-T13A with D-asn | | 分子名称: | Asparaginase, D-ASPARAGINE, FORMIC ACID, ... | | 著者 | Lu, F, Ran, T, Jiao, L, Wang, W. | | 登録日 | 2020-06-03 | | 公開日 | 2021-06-09 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | Structures of l-asparaginase from Bacillus licheniformis Reveal an Essential Residue for its Substrate Stereoselectivity.
J.Agric.Food Chem., 69, 2021
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7CBW
 | | Blasnase-T13A with D-asn | | 分子名称: | FORMIC ACID, L-asparaginase, MAGNESIUM ION | | 著者 | Lu, F, Ran, T, Jiao, L, Wang, W. | | 登録日 | 2020-06-15 | | 公開日 | 2021-06-09 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.978 Å) | | 主引用文献 | Structures of l-asparaginase from Bacillus licheniformis Reveal an Essential Residue for its Substrate Stereoselectivity.
J.Agric.Food Chem., 69, 2021
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7CBR
 | | Blasnase-T13A with D-asn | | 分子名称: | D-ASPARAGINE, FORMIC ACID, L-asparaginase, ... | | 著者 | Lu, F, Ran, T, Jiao, L, Wang, W. | | 登録日 | 2020-06-13 | | 公開日 | 2021-06-09 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structures of l-asparaginase from Bacillus licheniformis Reveal an Essential Residue for its Substrate Stereoselectivity.
J.Agric.Food Chem., 69, 2021
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7EO0
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6BN6
 | | IDENTIFICATION OF BICYCLIC HEXAFLUOROISOPROPYL ALCOHOL SULFONAMIDES AS RORGT/RORC INVERSE AGONISTS | | 分子名称: | 2-[(2S)-4-[(4-fluorophenyl)sulfonyl]-7-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-3,4-dihydro-2H-1,4-benzothiazin-2-yl]-N-(2-hydroxy-2-methylpropyl)acetamide, Nuclear receptor ROR-gamma, SULFATE ION | | 著者 | Sack, J. | | 登録日 | 2017-11-16 | | 公開日 | 2017-12-20 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Identification of bicyclic hexafluoroisopropyl alcohol sulfonamides as retinoic acid receptor-related orphan receptor gamma (ROR gamma /RORc) inverse agonists. Employing structure-based drug design to improve pregnane X receptor (PXR) selectivity.
Bioorg. Med. Chem. Lett., 28, 2018
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6CCY
 | | Crystal structure of Akt1 in complex with a selective inhibitor | | 分子名称: | (5R)-4-(4-{4-[4-fluoro-3-(trifluoromethyl)phenyl]-1-[2-(pyrrolidin-1-yl)ethyl]-1H-imidazol-2-yl}piperidin-1-yl)-5-methyl-5,8-dihydropyrido[2,3-d]pyrimidin-7(6H)-one, RAC-alpha serine/threonine-protein kinase,PIFtide | | 著者 | Wang, Y, Stout, S. | | 登録日 | 2018-02-07 | | 公開日 | 2018-05-02 | | 最終更新日 | 2018-05-16 | | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | | 主引用文献 | Discovery of chiral dihydropyridopyrimidinones as potent, selective and orally bioavailable inhibitors of AKT.
Bioorg. Med. Chem. Lett., 28, 2018
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7EL1
 | | Structure of a protein from bacteria | | 分子名称: | 100AA, CRISPR-associated endonuclease Cas9, DNA (28-MER), ... | | 著者 | Liu, H, Zhu, Y, Huang, Z. | | 登録日 | 2021-04-07 | | 公開日 | 2021-07-28 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | | 主引用文献 | Structural basis of Staphylococcus aureus Cas9 inhibition by AcrIIA14.
Nucleic Acids Res., 49, 2021
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6LIT
 | | Estrogen-related receptor beta(ERR2) in complex with BPA | | 分子名称: | 10-mer from Nuclear receptor coactivator 2, 4,4'-PROPANE-2,2-DIYLDIPHENOL, Steroid hormone receptor ERR2 | | 著者 | Yao, B.Q, Li, Y. | | 登録日 | 2019-12-13 | | 公開日 | 2020-10-07 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural Insights into the Specificity of Ligand Binding and Coactivator Assembly by Estrogen-Related Receptor beta.
J.Mol.Biol., 432, 2020
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6LN4
 | | Estrogen-related receptor beta(ERR2) in complex with PGC1a-2a | | 分子名称: | 10-mer from Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, Steroid hormone receptor ERR2 | | 著者 | Yao, B.Q, Li, Y. | | 登録日 | 2019-12-28 | | 公開日 | 2020-10-07 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | | 主引用文献 | Structural Insights into the Specificity of Ligand Binding and Coactivator Assembly by Estrogen-Related Receptor beta.
J.Mol.Biol., 432, 2020
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5VO6
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5WFJ
 | | THE JAK3 KINASE DOMAIN IN COMPLEX WITH A COVALENT INHIBITOR | | 分子名称: | 4-({[3-(propanoylamino)phenyl]methyl}amino)pyrrolo[1,2-b]pyridazine-3-carboxamide, Tyrosine-protein kinase JAK3 | | 著者 | Sack, J. | | 登録日 | 2017-07-12 | | 公開日 | 2017-10-04 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | Discovery of highly potent, selective, covalent inhibitors of JAK3.
Bioorg. Med. Chem. Lett., 27, 2017
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