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5MTJ
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BU of 5mtj by Molmil
Yes1-SH2 in complex with monobody Mb(Yes_1)
分子名称: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, Monobody Mb(Yes_1), SULFATE ION, ...
著者Sha, F, Kukenshoner, T, Koide, S, Hantschel, O.
登録日2017-01-09
公開日2017-04-05
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.949 Å)
主引用文献Selective Targeting of SH2 Domain-Phosphotyrosine Interactions of Src Family Tyrosine Kinases with Monobodies.
J. Mol. Biol., 429, 2017
5MTM
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BU of 5mtm by Molmil
Monobody Mb(Lck_3) bound to Lck-SH2 domain
分子名称: Monobody Mb(Lck_3), Tyrosine-protein kinase Lck, ZINC ION
著者Pojer, F, Kukenshoner, T, Koide, S, Hantschel, O.
登録日2017-01-10
公開日2017-04-05
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.405 Å)
主引用文献Selective Targeting of SH2 Domain-Phosphotyrosine Interactions of Src Family Tyrosine Kinases with Monobodies.
J. Mol. Biol., 429, 2017
6BF8
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BU of 6bf8 by Molmil
Cryo-EM structure of human insulin degrading enzyme in complex with insulin
分子名称: Insulin-degrading enzyme
著者Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J.
登録日2017-10-26
公開日2018-04-04
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
6BF6
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BU of 6bf6 by Molmil
Cryo-EM structure of human insulin degrading enzyme
分子名称: Insulin-degrading enzyme
著者Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J.
登録日2017-10-26
公開日2018-02-07
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (6.5 Å)
主引用文献Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
6BFC
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BU of 6bfc by Molmil
Cryo-EM structure of human insulin degrading enzyme in complex with insulin
分子名称: Insulin, Insulin-degrading enzyme
著者Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J.
登録日2017-10-26
公開日2017-12-27
最終更新日2021-04-28
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
6B3Q
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BU of 6b3q by Molmil
Cryo-EM structure of human insulin degrading enzyme in complex with insulin
分子名称: Insulin, Insulin-degrading enzyme
著者Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J.
登録日2017-09-22
公開日2017-11-22
最終更新日2021-04-28
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
6B7Y
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BU of 6b7y by Molmil
Cryo-EM structure of human insulin degrading enzyme
分子名称: Insulin-degrading enzyme
著者Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J.
登録日2017-10-05
公開日2017-11-08
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (6.5 Å)
主引用文献Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
6B7Z
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BU of 6b7z by Molmil
Cryo-EM structure of human insulin degrading enzyme in complex with FAB H11 heavy chain and FAB H11 light chain
分子名称: FAB H11 heavy chain, FAB H11 light chain, Insulin-degrading enzyme
著者Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J.
登録日2017-10-05
公開日2018-01-10
最終更新日2021-04-28
実験手法ELECTRON MICROSCOPY (6.5 Å)
主引用文献Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
6BF9
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BU of 6bf9 by Molmil
Cryo-EM structure of human insulin degrading enzyme in complex with FAB H11-E heavy chain, FAB H11-E light chain
分子名称: Fab H11-E heavy chain, Fab H11-E light chain, Insulin-degrading enzyme
著者Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J.
登録日2017-10-26
公開日2018-02-07
最終更新日2021-04-28
実験手法ELECTRON MICROSCOPY (7.2 Å)
主引用文献Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
6BF7
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BU of 6bf7 by Molmil
Cryo-EM structure of human insulin degrading enzyme in complex with FAB H11-E heavy chain, FAB H11-E light chain
分子名称: Fab H11-E heavy chain, Fab H11-E light chain, Insulin-degrading enzyme
著者Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J.
登録日2017-10-26
公開日2018-02-07
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (6.5 Å)
主引用文献Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
2I5Z
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BU of 2i5z by Molmil
The crystal structure of OspA mutant
分子名称: Outer surface protein A, TETRAETHYLENE GLYCOL
著者Makabe, K, Terechko, V, Koide, S.
登録日2006-08-26
公開日2007-07-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Hydrophobic surface burial is the major stability determinant of a flat, single-layer beta-sheet.
J.Mol.Biol., 368, 2007
5NKQ
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BU of 5nkq by Molmil
Crystal structure of a dual topology fluoride ion channel.
分子名称: FLUORIDE ION, Monobody, Putative fluoride ion transporter CrcB, ...
著者Stockbridge, R, Miller, C, Newstead, S.
登録日2017-03-31
公開日2017-04-26
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Crystal structures of a double-barrelled fluoride ion channel.
Nature, 525, 2015
4JMG
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BU of 4jmg by Molmil
Crystal structure of the synthetic protein in complex with pY peptide
分子名称: Clamp Ptpn11_pY580, MAGNESIUM ION, Tyrosine-protein phosphatase non-receptor type 11
著者Yasui, N, Smith, L, Koide, S.
登録日2013-03-14
公開日2014-04-23
最終更新日2014-08-06
実験手法X-RAY DIFFRACTION (1.403 Å)
主引用文献Directed network wiring identifies a key protein interaction in embryonic stem cell differentiation.
Mol.Cell, 54, 2014
4JE4
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BU of 4je4 by Molmil
Crystal Structure of Monobody NSa1/SHP2 N-SH2 Domain Complex
分子名称: Monobody NSa1, Tyrosine-protein phosphatase non-receptor type 11
著者Sha, F, Koide, S.
登録日2013-02-26
公開日2013-08-28
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Dissection of the BCR-ABL signaling network using highly specific monobody inhibitors to the SHP2 SH2 domains.
Proc.Natl.Acad.Sci.USA, 110, 2013
4JMH
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BU of 4jmh by Molmil
Crystal structure of synthetic protein in complex with double pY peptide
分子名称: Clamp Shc1_pY239/240, SHC-transforming protein 1
著者Yasui, N, Smith, L, Koide, S.
登録日2013-03-14
公開日2014-04-23
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.408 Å)
主引用文献Directed network wiring identifies a key protein interaction in embryonic stem cell differentiation.
Mol.Cell, 54, 2014
4JEG
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BU of 4jeg by Molmil
Crystal Structure of Monobody CS1/SHP2 C-SH2 Domain Complex
分子名称: Monobody CS1, Tyrosine-protein phosphatase non-receptor type 11
著者Sha, F, Koide, S.
登録日2013-02-26
公開日2013-08-28
最終更新日2014-03-12
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Dissection of the BCR-ABL signaling network using highly specific monobody inhibitors to the SHP2 SH2 domains.
Proc.Natl.Acad.Sci.USA, 110, 2013
5DC0
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BU of 5dc0 by Molmil
CRYSTAL STRUCTURE OF MONOBODY GG3/ABL1 SH2 DOMAIN COMPLEX
分子名称: Fibronectin, Tyrosine-protein kinase ABL1
著者Wojcik, J.B, Grabe, G, Koide, S.
登録日2015-08-22
公開日2016-03-02
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献Allosteric Inhibition of Bcr-Abl Kinase by High Affinity Monobody Inhibitors Directed to the Src Homology 2 (SH2)-Kinase Interface.
J.Biol.Chem., 291, 2016
5E08
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BU of 5e08 by Molmil
Specific Recognition of a Single-stranded RNA Sequence by an Engineered Synthetic Antibody Fragment
分子名称: Fab Heavy Chain, Fab Light Chain, RNA
著者Huang, H, Qin, D, Li, N, Shao, Y, Staley, J.P, Kossiakoff, A.A, Koide, S, Piccirilli, J.A.
登録日2015-09-28
公開日2016-09-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Specific Recognition of a Single-Stranded RNA Sequence by a Synthetic Antibody Fragment.
J.Mol.Biol., 428, 2016
6UX8
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BU of 6ux8 by Molmil
Structure of monobody 33 MLKL N-terminal domain complex
分子名称: Mixed lineage kinase domain-like protein, Monobody, ZINC ION
著者Birkinshaw, R.W, Petrie, E.J, Murphy, J.M.
登録日2019-11-07
公開日2020-04-01
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Identification of MLKL membrane translocation as a checkpoint in necroptotic cell death using Monobodies.
Proc.Natl.Acad.Sci.USA, 117, 2020
6WU1
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BU of 6wu1 by Molmil
Structure of apo LaINDY
分子名称: DASS family sodium-coupled anion symporter, DECANE, HEXANE, ...
著者Sauer, D.B, Marden, J.J, Cocco, N.C, Song, J.M, Wang, D.N, New York Consortium on Membrane Protein Structure (NYCOMPS)
登録日2020-05-04
公開日2020-09-16
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.09 Å)
主引用文献Structural basis for the reaction cycle of DASS dicarboxylate transporters.
Elife, 9, 2020
6WU2
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BU of 6wu2 by Molmil
Structure of the LaINDY-malate complex
分子名称: DASS family sodium-coupled anion symporter, DECANE, HEXANE, ...
著者Sauer, D.B, Marden, J.J, Cocco, N, Song, J.M, Wang, D.N, New York Consortium on Membrane Protein Structure (NYCOMPS)
登録日2020-05-04
公開日2020-09-16
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.36 Å)
主引用文献Structural basis for the reaction cycle of DASS dicarboxylate transporters.
Elife, 9, 2020
6WK8
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BU of 6wk8 by Molmil
Crystal structure of Gdx-Clo from Small Multidrug Resistance family of transporters in complex with phenylguanidinium
分子名称: 1-phenylguanidine, DECYL-BETA-D-MALTOPYRANOSIDE, Dodecyldimethylphosphine oxide, ...
著者Kermani, A.A, Stockbridge, R.B.
登録日2020-04-15
公開日2020-10-28
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献The structural basis of promiscuity in small multidrug resistance transporters.
Nat Commun, 11, 2020
6WTW
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BU of 6wtw by Molmil
Structure of LaINDY crystallized in the presence of alpha-ketoglutarate and malate
分子名称: DASS family sodium-coupled anion symporter
著者Sauer, D.B, Cocco, N, Marden, J.J, Song, J.M, Wang, D.N, New York Consortium on Membrane Protein Structure (NYCOMPS)
登録日2020-05-04
公開日2020-09-16
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献Structural basis for the reaction cycle of DASS dicarboxylate transporters.
Elife, 9, 2020
6WK5
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BU of 6wk5 by Molmil
Crystal structure of Gdx-Clo from Small Multidrug Resistance family of transporters
分子名称: L10 monobody, Multidrug resistance protein, SMR family
著者Kermani, A.A, Stockbridge, R.B.
登録日2020-04-15
公開日2020-10-28
最終更新日2020-12-09
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献The structural basis of promiscuity in small multidrug resistance transporters.
Nat Commun, 11, 2020
6WK9
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BU of 6wk9 by Molmil
Crystal structure of Gdx-Clo from Small Multidrug Resistance family of transporters in complex with octylguanidinium
分子名称: DECYL-BETA-D-MALTOPYRANOSIDE, L10 monobody, Multidrug resistance protein, ...
著者Kermani, A.A, Stockbridge, R.B.
登録日2020-04-15
公開日2020-10-28
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献The structural basis of promiscuity in small multidrug resistance transporters.
Nat Commun, 11, 2020

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