5EJK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ejk by Molmil](/molmil-images/mine/5ejk) | Crystal structure of the Rous sarcoma virus intasome | 分子名称: | DNA (5'-D(*AP*AP*TP*GP*TP*TP*GP*TP*CP*TP*TP*AP*TP*GP*CP*AP*AP*TP*AP*CP*TP*C)-3'), DNA (5'-D(*AP*GP*TP*GP*TP*CP*TP*T)-3'), DNA (5'-D(*CP*TP*TP*CP*TP*CP*TP*C)-3'), ... | 著者 | Yin, Z, Shi, K, Banerjee, S, Aihara, H. | 登録日 | 2015-11-02 | 公開日 | 2016-02-17 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Crystal structure of the Rous sarcoma virus intasome. Nature, 530, 2016
|
|
2Z7L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2z7l by Molmil](/molmil-images/mine/2z7l) | |
2Z8C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2z8c by Molmil](/molmil-images/mine/2z8c) | |
7UFK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ufk by Molmil](/molmil-images/mine/7ufk) | Crystal structure of chimeric omicron RBD (strain BA.2) complexed with human ACE2 | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zhang, W, Shi, K, Geng, Q, Ye, G, Aihara, H, Li, F. | 登録日 | 2022-03-22 | 公開日 | 2022-10-19 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | Structural basis for mouse receptor recognition by SARS-CoV-2 omicron variant. Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
7UFL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ufl by Molmil](/molmil-images/mine/7ufl) | Crystal structure of chimeric omicron RBD (strain BA.2) complexed with chimeric mouse ACE2 | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zhang, W, Shi, K, Geng, Q, Ye, G, Aihara, H, Li, F. | 登録日 | 2022-03-22 | 公開日 | 2022-10-19 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | 主引用文献 | Structural basis for mouse receptor recognition by SARS-CoV-2 omicron variant. Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
1Z19
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1z19 by Molmil](/molmil-images/mine/1z19) | Crystal structure of a lambda integrase(75-356) dimer bound to a COC' core site | 分子名称: | 33-MER, 5'-D(*CP*TP*CP*GP*TP*TP*CP*AP*GP*CP*TP*TP*TP*TP*TP*T)-3', 5'-D(P*TP*TP*TP*AP*TP*AP*CP*TP*AP*AP*GP*TP*TP*GP*GP*CP*AP*TP*TP*A)-3', ... | 著者 | Biswas, T, Aihara, H, Radman-Livaja, M, Filman, D, Landy, A, Ellenberger, T. | 登録日 | 2005-03-03 | 公開日 | 2005-06-28 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | A structural basis for allosteric control of DNA recombination by lambda integrase. Nature, 435, 2005
|
|
4NQ3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4nq3 by Molmil](/molmil-images/mine/4nq3) | Crystal structure of cyanuic acid hydrolase from A. caulinodans | 分子名称: | BARBITURIC ACID, Cyanuric acid amidohydrolase, MAGNESIUM ION, ... | 著者 | Cho, S, Shi, K, Aihara, H. | 登録日 | 2013-11-23 | 公開日 | 2014-09-10 | 実験手法 | X-RAY DIFFRACTION (2.702 Å) | 主引用文献 | Cyanuric acid hydrolase from Azorhizobium caulinodans ORS 571: crystal structure and insights into a new class of Ser-Lys dyad proteins. Plos One, 9, 2014
|
|
7UU0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7uu0 by Molmil](/molmil-images/mine/7uu0) | Crystal structure of the BRD2-BD2 in complex with a ligand | 分子名称: | 1,2-ETHANEDIOL, Isoform 3 of Bromodomain-containing protein 2, methyl (7S)-7-(thiophen-2-yl)-1,4-thiazepane-4-carboxylate | 著者 | Kalra, P, Shi, K, Aihara, H, Pomerantz, W.C.K. | 登録日 | 2022-04-28 | 公開日 | 2023-05-03 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Crystal structure of the BRD2-BD2 in complex with a ligand To Be Published
|
|
7U0N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7u0n by Molmil](/molmil-images/mine/7u0n) | Crystal structure of chimeric omicron RBD (strain BA.1) complexed with human ACE2 | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Geng, Q, Shi, K, Ye, G, Zhang, W, Aihara, H, Li, F. | 登録日 | 2022-02-18 | 公開日 | 2022-03-30 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | 主引用文献 | Structural Basis for Human Receptor Recognition by SARS-CoV-2 Omicron Variant BA.1. J.Virol., 96, 2022
|
|
1Z1B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1z1b by Molmil](/molmil-images/mine/1z1b) | Crystal structure of a lambda integrase dimer bound to a COC' core site | 分子名称: | 26-MER DNA, 29-MER DNA, 5'-D(*CP*T*CP*GP*TP*TP*CP*AP*GP*CP*TP*TP*TP*TP*TP*T)-3', ... | 著者 | Biswas, T, Aihara, H, Radman-Livaja, M, Filman, D, Landy, A, Ellenberger, T. | 登録日 | 2005-03-03 | 公開日 | 2005-06-28 | 最終更新日 | 2022-04-13 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | A structural basis for allosteric control of DNA recombination by lambda integrase. Nature, 435, 2005
|
|
1Z1G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1z1g by Molmil](/molmil-images/mine/1z1g) | Crystal structure of a lambda integrase tetramer bound to a Holliday junction | 分子名称: | 25-MER, 29-MER, 5'-D(*AP*CP*AP*GP*GP*TP*CP*AP*CP*TP*AP*TP*CP*AP*GP*TP*CP*AP*AP*AP*AP*TP*AP*CP*C)-3', ... | 著者 | Biswas, T, Aihara, H, Radman-Livaja, M, Filman, D, Landy, A, Ellenberger, T. | 登録日 | 2005-03-03 | 公開日 | 2005-06-28 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (4.4 Å) | 主引用文献 | A structural basis for allosteric control of DNA recombination by lambda integrase. Nature, 435, 2005
|
|
7K33
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7k33 by Molmil](/molmil-images/mine/7k33) | Crystal structure of Endonuclease Q complex with 27-mer duplex substrate with an abasic lesion at the active site | 分子名称: | DNA (27-MER), Endonuclease Q, MAGNESIUM ION, ... | 著者 | Shi, K, Moeller, N.M, Banerjee, S, Yin, L, Orellana, K, Aihara, H. | 登録日 | 2020-09-10 | 公開日 | 2021-03-17 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | 主引用文献 | Structural basis for recognition of distinct deaminated DNA lesions by endonuclease Q. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7K30
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7k30 by Molmil](/molmil-images/mine/7k30) | Crystal structure of Endonuclease Q complex with 27-mer duplex substrate with dU at the active site | 分子名称: | 1,2-ETHANEDIOL, DNA (27-MER), Endonuclease Q, ... | 著者 | Shi, K, Moeller, N.M, Banerjee, S, Yin, L, Orellana, K, Aihara, H. | 登録日 | 2020-09-10 | 公開日 | 2021-03-17 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | 主引用文献 | Structural basis for recognition of distinct deaminated DNA lesions by endonuclease Q. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7K32
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7k32 by Molmil](/molmil-images/mine/7k32) | Crystal structure of Endonuclease Q complex with 27-mer duplex substrate with an abasic lesion at the active site | 分子名称: | DNA (27-MER), Endonuclease Q, MAGNESIUM ION, ... | 著者 | Shi, K, Moeller, N.M, Banerjee, S, Yin, L, Orellana, K, Aihara, H. | 登録日 | 2020-09-10 | 公開日 | 2021-03-17 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | 主引用文献 | Structural basis for recognition of distinct deaminated DNA lesions by endonuclease Q. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7JN3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7jn3 by Molmil](/molmil-images/mine/7jn3) | Cryo-EM structure of Rous sarcoma virus cleaved synaptic complex (CSC) with HIV-1 integrase strand transfer inhibitor MK-2048 | 分子名称: | (6S)-2-(3-chloro-4-fluorobenzyl)-8-ethyl-10-hydroxy-N,6-dimethyl-1,9-dioxo-1,2,6,7,8,9-hexahydropyrazino[1',2':1,5]pyrrolo[2,3-d]pyridazine-4-carboxamide, DNA (5'-D(*AP*AP*TP*GP*TP*TP*GP*TP*CP*TP*TP*AP*TP*GP*CP*AP*AP*T)-3'), DNA (5'-D(*AP*TP*TP*GP*CP*AP*TP*AP*AP*GP*AP*CP*AP*AP*CP*A)-3'), ... | 著者 | Pandey, K.K, Bera, S, Shi, K, Aihara, H, Grandgenett, D.P. | 登録日 | 2020-08-03 | 公開日 | 2021-03-17 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.21 Å) | 主引用文献 | Cryo-EM structure of the Rous sarcoma virus octameric cleaved synaptic complex intasome. Commun Biol, 4, 2021
|
|
7K31
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7k31 by Molmil](/molmil-images/mine/7k31) | Crystal structure of Endonuclease Q complex with 27-mer duplex substrate with dI at the active site | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, DNA (27-MER), ... | 著者 | Shi, K, Moeller, N.M, Banerjee, S, Yin, L, Orellana, K, Aihara, H. | 登録日 | 2020-09-10 | 公開日 | 2021-03-17 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.88 Å) | 主引用文献 | Structural basis for recognition of distinct deaminated DNA lesions by endonuclease Q. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7KUI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7kui by Molmil](/molmil-images/mine/7kui) | Cryo-EM structure of Rous sarcoma virus cleaved synaptic complex (CSC) with HIV-1 integrase strand transfer inhibitor MK-2048. CIC region of a cluster identified by 3-dimensional variability analysis in cryoSPARC. | 分子名称: | (6S)-2-(3-chloro-4-fluorobenzyl)-8-ethyl-10-hydroxy-N,6-dimethyl-1,9-dioxo-1,2,6,7,8,9-hexahydropyrazino[1',2':1,5]pyrrolo[2,3-d]pyridazine-4-carboxamide, DNA (5'-D(*AP*AP*TP*GP*TP*TP*GP*TP*CP*TP*TP*AP*TP*GP*CP*AP*AP*T)-3'), DNA (5'-D(*AP*TP*TP*GP*CP*AP*TP*AP*AP*GP*AP*CP*AP*AP*CP*A)-3'), ... | 著者 | Pandey, K.K, Bera, S, Shi, K, Aihara, H, Grandgenett, D.P. | 登録日 | 2020-11-25 | 公開日 | 2021-03-17 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Cryo-EM structure of the Rous sarcoma virus octameric cleaved synaptic complex intasome. Commun Biol, 4, 2021
|
|
7KU7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ku7 by Molmil](/molmil-images/mine/7ku7) | Cryo-EM structure of Rous sarcoma virus cleaved synaptic complex (CSC) with HIV-1 integrase strand transfer inhibitor MK-2048. Cluster identified by 3-dimensional variability analysis in cryoSPARC. | 分子名称: | (6S)-2-(3-chloro-4-fluorobenzyl)-8-ethyl-10-hydroxy-N,6-dimethyl-1,9-dioxo-1,2,6,7,8,9-hexahydropyrazino[1',2':1,5]pyrrolo[2,3-d]pyridazine-4-carboxamide, DNA (5'-D(*AP*AP*TP*GP*TP*TP*GP*TP*CP*TP*TP*AP*TP*GP*CP*AP*AP*T)-3'), DNA (5'-D(*AP*TP*TP*GP*CP*AP*TP*AP*AP*GP*AP*CP*AP*AP*CP*A)-3'), ... | 著者 | Pandey, K.K, Bera, S, Shi, K, Aihara, H, Grandgenett, D.P. | 登録日 | 2020-11-24 | 公開日 | 2021-03-17 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Cryo-EM structure of the Rous sarcoma virus octameric cleaved synaptic complex intasome. Commun Biol, 4, 2021
|
|
4YJ0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4yj0 by Molmil](/molmil-images/mine/4yj0) | Crystal structure of the DM domain of human DMRT1 bound to 25mer target DNA | 分子名称: | DNA (25-MER), Doublesex- and mab-3-related transcription factor 1, ZINC ION | 著者 | Murphy, M.W, Lee, J.K, Rojo, S, Gearhart, M.D, Kurahashi, K, Banerjee, S, Loeuille, G, Bashamboo, A, McElreavey, K, Zarkower, D, Aihara, H, Bardwell, V.J. | 登録日 | 2015-03-02 | 公開日 | 2015-05-27 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (3.814 Å) | 主引用文献 | An ancient protein-DNA interaction underlying metazoan sex determination. Nat.Struct.Mol.Biol., 22, 2015
|
|
5WFY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5wfy by Molmil](/molmil-images/mine/5wfy) | |
5W8X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5w8x by Molmil](/molmil-images/mine/5w8x) | Lipid A Disaccharide Synthase (LpxB)-7 solubilizing mutations-Bound to UDP | 分子名称: | Lipid-A-disaccharide synthase, URIDINE-5'-DIPHOSPHATE | 著者 | Bohl, T.E, Aihara, H, Shi, K, Lee, J.K. | 登録日 | 2017-06-22 | 公開日 | 2018-01-31 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Crystal structure of lipid A disaccharide synthase LpxB from Escherichia coli. Nat Commun, 9, 2018
|
|
5WLY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5wly by Molmil](/molmil-images/mine/5wly) | E. coli LpxH- 8 mutations | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, FORMIC ACID, ... | 著者 | Bohl, T.E, Aihara, H, Shi, K, Lee, J.K. | 登録日 | 2017-07-28 | 公開日 | 2018-04-11 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The substrate-binding cap of the UDP-diacylglucosamine pyrophosphatase LpxH is highly flexible, enabling facile substrate binding and product release. J. Biol. Chem., 293, 2018
|
|
5W8N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5w8n by Molmil](/molmil-images/mine/5w8n) | |
5W8S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5w8s by Molmil](/molmil-images/mine/5w8s) | Lipid A Disaccharide Synthase (LpxB)-7 solubilizing mutations | 分子名称: | LITHIUM ION, Lipid-A-disaccharide synthase, SODIUM ION | 著者 | Bohl, T.E, Aihara, H, Shi, K, Lee, J.K. | 登録日 | 2017-06-22 | 公開日 | 2018-01-31 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of lipid A disaccharide synthase LpxB from Escherichia coli. Nat Commun, 9, 2018
|
|
5Y34
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5y34 by Molmil](/molmil-images/mine/5y34) | Membrane-bound respiratory [NiFe]-hydrogenase from Hydrogenovibrio marinus in a ferricyanide-oxidized condition | 分子名称: | CARBONMONOXIDE-(DICYANO) IRON, FE3-S4 CLUSTER, FE4-S3 CLUSTER, ... | 著者 | Shomura, Y, Yoon, K.S, Nishihara, H, Higuchi, Y. | 登録日 | 2017-07-27 | 公開日 | 2017-08-16 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.32 Å) | 主引用文献 | Structural basis for a [4Fe-3S] cluster in the oxygen-tolerant membrane-bound [NiFe]-hydrogenase Nature, 479, 2011
|
|