8HBC
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![BU of 8hbc by Molmil](/molmil-images/mine/8hbc) | Crystal structure of the CysR-CTLD3 fragment of human DEC205 | 分子名称: | Lymphocyte antigen 75 | 著者 | Kong, D, Yu, B, Hu, Z, Cheng, C, Cao, L, He, Y. | 登録日 | 2022-10-28 | 公開日 | 2023-11-01 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | 主引用文献 | Interaction of human dendritic cell receptor DEC205/CD205 with keratins. J.Biol.Chem., 300, 2024
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7UDQ
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![BU of 7udq by Molmil](/molmil-images/mine/7udq) | Crystal structure of COQ8A-CA157 inhibitor complex in space group P1 | 分子名称: | 4-[(3,4,5-trimethoxyphenyl)amino]quinoline-7-carbonitrile, Atypical kinase COQ8A, mitochondrial, ... | 著者 | Bingman, C.A, Murray, N, Smith, R.W, Pagliarini, D.J. | 登録日 | 2022-03-20 | 公開日 | 2023-01-18 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Small-molecule inhibition of the archetypal UbiB protein COQ8. Nat.Chem.Biol., 19, 2023
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7UDP
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![BU of 7udp by Molmil](/molmil-images/mine/7udp) | Crystal structure of COQ8A-CA157 inhibitor complex in space group C2 | 分子名称: | 4-[(3,4,5-trimethoxyphenyl)amino]quinoline-7-carbonitrile, Atypical kinase COQ8A, mitochondrial | 著者 | Bingman, C.A, Murray, N, Smith, R.W, Pagliarini, D.J. | 登録日 | 2022-03-20 | 公開日 | 2023-01-18 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Small-molecule inhibition of the archetypal UbiB protein COQ8. Nat.Chem.Biol., 19, 2023
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8HHT
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![BU of 8hht by Molmil](/molmil-images/mine/8hht) | Crystal structure of the SARS-CoV-2 main protease in complex with Hit-1 | 分子名称: | 3C-like proteinase nsp5, DIMETHYL SULFOXIDE, ~{N}-[(2~{R},3~{S})-3-oxidanyl-4-oxidanylidene-1-phenyl-4-(1,3-thiazol-2-ylmethylamino)butan-2-yl]benzamide | 著者 | Zeng, R, Xie, L.W, Huang, C, Wang, K, Liu, Y.Z, Yang, S.Y, Lei, J. | 登録日 | 2022-11-17 | 公開日 | 2023-03-29 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | A new generation M pro inhibitor with potent activity against SARS-CoV-2 Omicron variants. Signal Transduct Target Ther, 8, 2023
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8HHU
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![BU of 8hhu by Molmil](/molmil-images/mine/8hhu) | Crystal structure of the SARS-CoV-2 main protease in complex with SY110 | 分子名称: | (1~{R})-3,3-bis(fluoranyl)-~{N}-[(2~{R})-3-methoxy-1-oxidanylidene-1-[[(2~{R},3~{S})-3-oxidanyl-4-oxidanylidene-1-phenyl-4-(1,3-thiazol-2-ylmethylamino)butan-2-yl]amino]propan-2-yl]cyclohexane-1-carboxamide, 3C-like proteinase nsp5 | 著者 | Zeng, R, Xie, L.W, Huang, C, Wang, K, Liu, Y.Z, Yang, S.Y, Lei, J. | 登録日 | 2022-11-17 | 公開日 | 2023-03-29 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.258 Å) | 主引用文献 | A new generation M pro inhibitor with potent activity against SARS-CoV-2 Omicron variants. Signal Transduct Target Ther, 8, 2023
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8I30
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![BU of 8i30 by Molmil](/molmil-images/mine/8i30) | Crystal structure of the SARS-CoV-2 main protease in complex with 32j | 分子名称: | (2~{R})-1-[4,4-bis(fluoranyl)cyclohexyl]carbonyl-4,4-bis(fluoranyl)-~{N}-[(2~{R},3~{S})-3-oxidanyl-4-oxidanylidene-1-phenyl-4-(pyridin-2-ylmethylamino)butan-2-yl]pyrrolidine-2-carboxamide, 3C-like proteinase nsp5, CHLORIDE ION | 著者 | Zeng, R, Huang, C, Xie, L.W, Wang, K, Liu, Y.Z, Yang, S.Y, Lei, J. | 登録日 | 2023-01-16 | 公開日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Discovery and structure-activity relationship studies of novel alpha-ketoamide derivatives targeting the SARS-CoV-2 main protease. Eur.J.Med.Chem., 259, 2023
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7CLZ
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![BU of 7clz by Molmil](/molmil-images/mine/7clz) | |