131D
| THE LOW-TEMPERATURE CRYSTAL STRUCTURE OF THE PURE-SPERMINE FORM OF Z-DNA REVEALS BINDING OF A SPERMINE MOLECULE IN THE MINOR GROOVE | 分子名称: | DNA (5'-D(*CP*GP*CP*GP*CP*G)-3'), SODIUM ION, SPERMINE | 著者 | Bancroft, D, Williams, L.D, Rich, A, Egli, M. | 登録日 | 1993-06-18 | 公開日 | 1993-10-15 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1 Å) | 主引用文献 | The low-temperature crystal structure of the pure-spermine form of Z-DNA reveals binding of a spermine molecule in the minor groove. Biochemistry, 33, 1994
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6B82
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5V2H
| RNA octamer containing glycol nucleic acid, SgnT | 分子名称: | COBALT HEXAMMINE(III), MAGNESIUM ION, RNA (5'-R(*(CBV)P*GP*AP*AP*(ZTH)P*UP*CP*G)-3') | 著者 | Harp, J.M, Egli, M. | 登録日 | 2017-03-04 | 公開日 | 2017-06-14 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.080013 Å) | 主引用文献 | Chirality Dependent Potency Enhancement and Structural Impact of Glycol Nucleic Acid Modification on siRNA. J. Am. Chem. Soc., 139, 2017
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4Y8W
| Crystal Structure of Human Cytochrome P450 21A2 Progesterone Complex | 分子名称: | Cytochrome P450 21-hydroxylase, PROGESTERONE, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Pallan, P.S, Lei, L, Egli, M. | 登録日 | 2015-02-16 | 公開日 | 2015-04-15 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | 主引用文献 | Human Cytochrome P450 21A2, the Major Steroid 21-Hydroxylase: STRUCTURE OF THE ENZYMEPROGESTERONE SUBSTRATE COMPLEX AND RATE-LIMITING C-H BOND CLEAVAGE. J.Biol.Chem., 290, 2015
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5V1K
| Structure of R-GNA dodecamer | 分子名称: | RNA (5'-R(*CP*GP*CP*GP*AP*AP*(5BU)P*(8RJ)P*AP*GP*CP*G)-3') | 著者 | Pallan, P.S, Egli, M. | 登録日 | 2017-03-02 | 公開日 | 2017-06-21 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.18 Å) | 主引用文献 | Chirality Dependent Potency Enhancement and Structural Impact of Glycol Nucleic Acid Modification on siRNA. J. Am. Chem. Soc., 2017
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5V1L
| Structure of S-GNA dodecamer | 分子名称: | RNA (5'-R(*CP*GP*CP*GP*AP*AP*UP*(ZTH)P*AP*GP*CP*G)-3'), SPERMINE, STRONTIUM ION | 著者 | Pallan, P.S, Egli, M. | 登録日 | 2017-03-02 | 公開日 | 2017-06-14 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Chirality Dependent Potency Enhancement and Structural Impact of Glycol Nucleic Acid Modification on siRNA. J. Am. Chem. Soc., 139, 2017
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2JEG
| The Molecular Basis of Selectivity of Nucleoside Triphosphate Incorporation Opposite O6-Benzylguanine by Sulfolobus solfataricus DNA Polymerase IV: Steady-state and Pre-steady-state Kinetics and X- Ray Crystallography of Correct and Incorrect Pairing | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP *TP*TP*CP*DOC)-3', 5'-D(*TP*CP*AP*C BZGP*GP*AP*AP*TP*CP *CP*TP*TP*CP*CP*CP*CP*C)-3', ... | 著者 | Eoff, R.L, Angel, K.C, Kosekov, I.D, Egli, M, Guengerich, F.P. | 登録日 | 2007-01-17 | 公開日 | 2007-03-13 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | Molecular Basis of Selectivity of Nucleoside Triphosphate Incorporation Opposite O6-Benzylguanine by Sulfolobus Solfataricus DNA Polymerase Dpo4: Steady-State and Pre-Steady-State Kinetics and X-Ray Crystallography of Correct and Incorrect Pairing. J.Biol.Chem., 282, 2007
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2JEI
| The Molecular Basis of Selectivity of Nucleoside Triphosphate Incorporation Opposite O6-Benzylguanine by Sulfolobus solfataricus DNA Polymerase IV: Steady-state and Pre-steady-state Kinetics and X- Ray Crystallography of Correct and Incorrect Pairing | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP *TP*TP*CP*T)-3', 5'-D(*TP*CP*AP*C BZGP*GP*AP*AP*TP*CP*CP *TP*TP*CP*CP*CP*CP*C)-3', ... | 著者 | Eoff, R.L, Angel, K.C, Kosekov, I.D, Egli, M, Guengerich, F.P. | 登録日 | 2007-01-17 | 公開日 | 2007-03-13 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | Molecular Basis of Selectivity of Nucleoside Triphosphate Incorporation Opposite O6-Benzylguanine by Sulfolobus Solfataricus DNA Polymerase Dpo4: Steady-State and Pre-Steady-State Kinetics and X-Ray Crystallography of Correct and Incorrect Pairing. J.Biol.Chem., 282, 2007
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2JEF
| The Molecular Basis of Selectivity of Nucleotide Triphosphate Incorporation Opposite O6-Benzylguanine by Sulfolobus solfataricus DNA Polymerase IV: Steady-state and Pre-steady-state and X-Ray Crystallography of Correct and Incorrect Pairing | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP*TP*TP*CP*DOC)-3', 5'-D(*TP*CP*AP*CP*BZGP*GP*AP*AP*TP*CP*CP*TP*TP*CP*CP CP*CP*C)-3', ... | 著者 | Eoff, R.L, Angel, K.C, Kosekov, I.D, Egli, M, Guengerich, F.P. | 登録日 | 2007-01-17 | 公開日 | 2007-03-13 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | Molecular Basis of Selectivity of Nucleoside Triphosphate Incorporation Opposite O6-Benzylguanine by Sulfolobus Solfataricus DNA Polymerase Dpo4: Steady-State and Pre-Steady-State Kinetics and X-Ray Crystallography of Correct and Incorrect Pairing. J.Biol.Chem., 282, 2007
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2JEJ
| The Molecular Basis of Selectivity of Nucleoside Triphosphate Incorporation Opposite O6-Benzylguanine by Sulfolobus solfataricus DNA Polymerase IV: Steady-state and Pre-steady-state Kinetics and X- Ray Crystallography of Correct and Incorrect Pairing | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP *TP*TP*CP*CP*G)-3', 5'-D(*TP*CP*AP*C BZGP*GP*AP*AP*TP*CP*CP *TP*TP*CP*CP*CP*CP*C)-3', ... | 著者 | Eoff, R.L, Angel, K.C, Kosekov, I.D, Egli, M, Guengerich, F.P. | 登録日 | 2007-01-17 | 公開日 | 2007-03-13 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Molecular Basis of Selectivity of Nucleoside Triphosphate Incorporation Opposite O6-Benzylguanine by Sulfolobus Solfataricus DNA Polymerase Dpo4: Steady-State and Pre-Steady-State Kinetics and X-Ray Crystallography of Correct and Incorrect Pairing. J.Biol.Chem., 282, 2007
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9BF2
| MID domain of Ago2 bound to UMP | 分子名称: | Protein argonaute-2, URIDINE-5'-MONOPHOSPHATE | 著者 | Harp, J.M, Egli, M. | 登録日 | 2024-04-16 | 公開日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | 主引用文献 | Structure and Stability of Ago2 MID-Nucleotide Complexes: All-in-One (Drop) His 6 -SUMO Tag Removal, Nucleotide Binding, and Crystal Growth. Curr Protoc, 4, 2024
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9BF0
| MID domain of human Argo2 bound to UTP | 分子名称: | Protein argonaute-2, URIDINE 5'-TRIPHOSPHATE | 著者 | Harp, J.M, Egli, M. | 登録日 | 2024-04-16 | 公開日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Structure and Stability of Ago2 MID-Nucleotide Complexes: All-in-One (Drop) His 6 -SUMO Tag Removal, Nucleotide Binding, and Crystal Growth. Curr Protoc, 4, 2024
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9BEZ
| MID domain of human Argo2 bound to RNA | 分子名称: | Protein argonaute-2, [(3~{S},4~{R},5~{R})-5-[5-methyl-2,4-bis(oxidanylidene)pyrimidin-1-yl]-4-oxidanyl-oxolan-3-yl] [oxidanyl(phosphonooxy)phosphoryl] hydrogen phosphate | 著者 | Harp, J.M, Egli, M. | 登録日 | 2024-04-16 | 公開日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure and Stability of Ago2 MID-Nucleotide Complexes: All-in-One (Drop) His 6 -SUMO Tag Removal, Nucleotide Binding, and Crystal Growth. Curr Protoc, 4, 2024
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1D32
| DRUG-INDUCED DNA REPAIR: X-RAY STRUCTURE OF A DNA-DITERCALINIUM COMPLEX | 分子名称: | DITERCALINIUM, DNA (5'-D(*CP*GP*CP*G)-3') | 著者 | Gao, Q, Williams, L.D, Egli, M, Rabinovich, D, Chen, S.-L, Quigley, G.J, Rich, A. | 登録日 | 1991-01-23 | 公開日 | 1992-04-15 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Drug-induced DNA repair: X-ray structure of a DNA-ditercalinium complex. Proc.Natl.Acad.Sci.USA, 88, 1991
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1CS7
| SYNTHETIC DNA HAIRPIN WITH STILBENEDIETHER LINKER | 分子名称: | 5'-D(GP*(BRU)P*TP*TP*TP*GP*(S02)*CP*AP*AP*AP*AP*C)-3', STRONTIUM ION | 著者 | Lewis, F.D, Liu, X, Wu, Y, Miller, S.E, Wasielewski, M.R, Letsinger, R.L, Sanishvili, R, Joachimiak, A, Tereshko, V, Egli, M. | 登録日 | 1999-08-17 | 公開日 | 2001-10-19 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structure and Photoinduced Electron Transfer in Exceptionally Stable Synthetic DNA Hairpins with Stilbenediether Linkers J.Am.Chem.Soc., 121, 1999
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363D
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388D
| CRYSTAL STRUCTURE OF B-DNA WITH INCORPORATED 2'-DEOXY-2'-FLUORO-ARABINO-FURANOSYL THYMINES: IMPLICATIONS OF CONFORMATIONAL PREORGANIZATION FOR DUPLEX STABILITY | 分子名称: | DNA (5'-D(*CP*GP*CP*GP*AP*AP*(TAF)P*(TAF)P*CP*GP*CP*G)-3'), MAGNESIUM ION | 著者 | Berger, I, Tereshko, V, Ikeda, H, Marquez, V.E, Egli, M. | 登録日 | 1998-04-20 | 公開日 | 1998-05-05 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Crystal structures of B-DNA with incorporated 2'-deoxy-2'-fluoro-arabino-furanosyl thymines: implications of conformational preorganization for duplex stability. Nucleic Acids Res., 26, 1998
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389D
| CRYSTAL STRUCTURE OF B-DNA WITH INCORPORATED 2'-DEOXY-2'-FLUORO-ARABINO-FURANOSYL THYMINES: IMPLICATIONS OF CONFORMATIONAL PREORGANIZATION FOR DUPLEX STABILITY | 分子名称: | DNA (5'-D(*CP*GP*CP*GP*AP*AP*(TAF)P*TP*CP*GP*CP*G)-3'), MAGNESIUM ION | 著者 | Berger, I, Tereshko, V, Ikeda, H, Marquez, V.E, Egli, M. | 登録日 | 1998-04-20 | 公開日 | 1998-05-05 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Crystal structures of B-DNA with incorporated 2'-deoxy-2'-fluoro-arabino-furanosyl thymines: implications of conformational preorganization for duplex stability. Nucleic Acids Res., 26, 1998
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1D14
| STRUCTURE OF 11-DEOXYDAUNOMYCIN BOUND TO DNA CONTAINING A PHOSPHOROTHIOATE | 分子名称: | 6-DEOXYDAUNOMYCIN, DNA (5'-D(*CP*GP*TP*(AS)P*CP*G)-3') | 著者 | Williams, L.D, Egli, M, Ughetto, G, Van Der Marel, G.A, Van Boom, J.H, Quigley, G.J, Wang, A.H.-J, Rich, A, Frederick, C.A. | 登録日 | 1989-10-20 | 公開日 | 1990-10-15 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structure of 11-deoxydaunomycin bound to DNA containing a phosphorothioate. J.Mol.Biol., 215, 1990
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3K0A
| Crystal structure of the phosphorylation-site mutant S431A of the KaiC circadian clock protein | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Circadian clock protein kinase KaiC, MAGNESIUM ION | 著者 | Pattanayek, R, Egli, M, Pattanayek, S. | 登録日 | 2009-09-24 | 公開日 | 2010-03-31 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structures of KaiC Circadian Clock Mutant Proteins: A New Phosphorylation Site at T426 and Mechanisms of Kinase, ATPase and Phosphatase. Plos One, 4, 2009
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3K09
| Crystal structure of the phosphorylation-site mutant S431D of the KaiC circadian clock protein | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Circadian clock protein kinase kaiC, MAGNESIUM ION | 著者 | Pattanayek, R, Egli, M, Pattanayek, S. | 登録日 | 2009-09-24 | 公開日 | 2010-03-31 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structures of KaiC Circadian Clock Mutant Proteins: A New Phosphorylation Site at T426 and Mechanisms of Kinase, ATPase and Phosphatase. Plos One, 4, 2009
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3K0E
| Crystal structure of the phosphorylation-site mutant T426N of the KaiC circadian clock protein | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Circadian clock protein kinase KaiC, MAGNESIUM ION | 著者 | Pattanayek, R, Egli, M, Pattanayek, S. | 登録日 | 2009-09-24 | 公開日 | 2010-03-31 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structures of KaiC Circadian Clock Mutant Proteins: A New Phosphorylation Site at T426 and Mechanisms of Kinase, ATPase and Phosphatase. Plos One, 4, 2009
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1DAU
| Analog of dickerson-drew DNA dodecamer with 6'-alpha-methyl carbocyclic thymidines, NMR, minimized average structure | 分子名称: | DNA (5'-D(*CP*GP*CP*GP*AP*AP*(T32)P*(T32)P*CP*GP*CP*G)-3') | 著者 | Denisov, A, Bekiroglu, S, Maltseva, T, Sandstrom, A, Altmann, K.-H, Egli, M, Chattopadhyaya, J. | 登録日 | 1998-01-21 | 公開日 | 1998-05-27 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | The solution conformation of a carbocyclic analog of the Dickerson-Drew dodecamer: comparison with its own X-ray structure and that of the NMR structure of the native counterpart. J.Biomol.Struct.Dyn., 16, 1998
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3K0F
| Crystal structure of the phosphorylation-site double mutant T426A/T432A of the KaiC circadian clock protein | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Circadian clock protein kinase KaiC, MAGNESIUM ION | 著者 | Pattanayek, R, Egli, M, Pattanayek, S. | 登録日 | 2009-09-24 | 公開日 | 2010-03-31 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structures of KaiC Circadian Clock Mutant Proteins: A New Phosphorylation Site at T426 and Mechanisms of Kinase, ATPase and Phosphatase. Plos One, 4, 2009
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3K0C
| Crystal structure of the phosphorylation-site double mutant S431A/T432E of the KaiC circadian clock protein | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Circadian clock protein kinase KaiC, MAGNESIUM ION | 著者 | Pattanayek, R, Egli, M, Pattanayek, S. | 登録日 | 2009-09-24 | 公開日 | 2010-03-31 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structures of KaiC Circadian Clock Mutant Proteins: A New Phosphorylation Site at T426 and Mechanisms of Kinase, ATPase and Phosphatase. Plos One, 4, 2009
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