5V2H

RNA octamer containing glycol nucleic acid, SgnT

Summary for 5V2H

• Entry DOI: 10.2210/pdb5v2h/pdb
• Descriptor: RNA (5'-R(*(CBV)P*GP*AP*AP*(ZTH)P*UP*CP*G)-3'), COBALT HEXAMMINE(III), MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: rna, glycol nucleic acid
• Biological source: synthetic construct
• Total number of polymer chains: 4
• Total formula weight: 10431.21

Authors

Harp, J.M.,Egli, M. (deposition date: 2017-03-04, release date: 2017-06-14, Last modification date: 2022-06-22)

• Primary citation: Schlegel, M.K.,Foster, D.J.,Kel'in, A.V.,Zlatev, I.,Bisbe, A.,Jayaraman, M.,Lackey, J.G.,Rajeev, K.G.,Charisse, K.,Harp, J.,Pallan, P.S.,Maier, M.A.,Egli, M.,Manoharan, M.; Chirality Dependent Potency Enhancement and Structural Impact of Glycol Nucleic Acid Modification on siRNA.; J. Am. Chem. Soc., 139:8537-8546, 2017; PubMed: 28570818; DOI: 10.1021/jacs.7b02694

Experimental method

X-RAY DIFFRACTION (1.08001306231 Å)