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8I4B
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BU of 8i4b by Molmil
Cryo-EM structure of apo-form ABCC4
分子名称: ATP-binding cassette sub-family C member 4
著者Chen, Y, Wang, L, Hou, W.T, Zhou, C.Z, Chen, Y, Li, Q.
登録日2023-01-19
公開日2023-05-24
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.13 Å)
主引用文献Cryo-EM structure ofABCC4
Nat Cardiovasc Res, 2023
8I4A
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BU of 8i4a by Molmil
Cryo-EM structure of dipyridamole-bound ABCC4
分子名称: 2-[[2-[bis(2-hydroxyethyl)amino]-4,8-di(piperidin-1-yl)pyrimido[5,4-d]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethanol, ATP-binding cassette sub-family C member 4
著者Chen, Y, Wang, L, Hou, W.T, Zhou, C.Z, Chen, Y, Li, Q.
登録日2023-01-19
公開日2023-05-24
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM structure ofABCC4
Nat Cardiovasc Res, 2023
8I4C
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BU of 8i4c by Molmil
Cryo-EM structure of U46619-bound ABCC4
分子名称: (5Z)-7-{(1R,4S,5S,6R)-6-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2-oxabicyclo[2.2.1]hept-5-yl}hept-5-enoic acid, ATP-binding cassette sub-family C member 4
著者Chen, Y, Wang, L, Hou, W.T, Zhou, C.Z, Chen, Y, Li, Q.
登録日2023-01-19
公開日2023-05-24
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.08 Å)
主引用文献Cryo-EM structure ofABCC4
Nat Cardiovasc Res, 2023
5GTD
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BU of 5gtd by Molmil
o-Succinylbenzoate CoA Synthetase (MenE) from Bacillus Subtilis in Complex with the Acyl-adenylate Intermediate OSB-AMP
分子名称: 2-SUCCINYLBENZOATE, 2-succinylbenzoate--CoA ligase, ADENOSINE MONOPHOSPHATE, ...
著者Chen, Y, Guo, Z.
登録日2016-08-20
公開日2017-01-04
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Mechanistic Insights from the Crystal Structure of Bacillus subtilis o-Succinylbenzoyl-CoA Synthetase Complexed with the Adenylate Intermediate
Biochemistry, 55, 2016
2HKO
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BU of 2hko by Molmil
Crystal structure of LSD1
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Lysine-specific histone demethylase 1
著者Chen, Y, Yang, Y.T, Wang, F, Yanane, K, Zhang, Y, Lei, M.
登録日2006-07-05
公開日2006-08-29
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of human histone lysine-specific demethylase 1 (LSD1).
Proc.Natl.Acad.Sci.Usa, 103, 2006
5GTM
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BU of 5gtm by Molmil
Modified human MxA, nucleotide-free form
分子名称: Interferon-induced GTP-binding protein Mx1
著者Chen, Y, Gao, S.
登録日2016-08-22
公開日2017-05-31
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.896 Å)
主引用文献Conformational dynamics of dynamin-like MxA revealed by single-molecule FRET
Nat Commun, 8, 2017
3G2Z
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BU of 3g2z by Molmil
CTX-M-9 class A beta-lactamase complexed with compound 2 (GZ2)
分子名称: 3-(1H-tetrazol-5-ylamino)cyclohex-2-en-1-one, Beta-lactamase CTX-M-9a, DIMETHYL SULFOXIDE
著者Chen, Y, Shoichet, B.K.
登録日2009-02-01
公開日2009-03-24
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Molecular docking and ligand specificity in fragment-based inhibitor discovery
Nat.Chem.Biol., 5, 2009
3ITA
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BU of 3ita by Molmil
Crystal structure of Penicillin-Binding Protein 6 (PBP6) from E. coli in acyl-enzyme complex with ampicillin
分子名称: (2R,4S)-2-[(1R)-1-{[(2R)-2-amino-2-phenylacetyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, (2S,5R,6R)-6-{[(2R)-2-AMINO-2-PHENYLETHANOYL]AMINO}-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID, D-alanyl-D-alanine carboxypeptidase dacC, ...
著者Chen, Y, Zhang, W, Shi, Q, Hesek, D, Lee, M, Mobashery, S, Shoichet, B.K.
登録日2009-08-27
公開日2009-10-20
最終更新日2024-11-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structures of penicillin-binding protein 6 from Escherichia coli.
J.Am.Chem.Soc., 131, 2009
3IT9
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BU of 3it9 by Molmil
Crystal structure of Penicillin-Binding Protein 6 (PBP6) from E. coli in apo state
分子名称: D-alanyl-D-alanine carboxypeptidase dacC, SULFATE ION, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose
著者Chen, Y, Zhang, W, Shi, Q, Hesek, D, Lee, M, Mobashery, S, Shoichet, B.K.
登録日2009-08-27
公開日2009-10-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structures of penicillin-binding protein 6 from Escherichia coli.
J.Am.Chem.Soc., 131, 2009
3G31
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BU of 3g31 by Molmil
CTX-M-9 class A beta-lactamase complexed with compound 4 (GF1)
分子名称: (2S)-2-[(3aR,4R,7S,7aS)-1,3-dioxooctahydro-2H-4,7-methanoisoindol-2-yl]propanoic acid, Beta-lactamase CTX-M-9a, DIMETHYL SULFOXIDE, ...
著者Chen, Y, Shoichet, B.K.
登録日2009-02-01
公開日2009-03-24
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Molecular docking and ligand specificity in fragment-based inhibitor discovery
Nat.Chem.Biol., 5, 2009
3G30
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BU of 3g30 by Molmil
CTX-M-9 class A beta-lactamase complexed with compound 3 (G30)
分子名称: (1S,2R)-2-[(2,5-difluorophenyl)carbamoyl]cyclopropanecarboxylic acid, Beta-lactamase CTX-M-9a
著者Chen, Y, Shoichet, B.K.
登録日2009-02-01
公開日2009-03-24
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Molecular docking and ligand specificity in fragment-based inhibitor discovery
Nat.Chem.Biol., 5, 2009
3G32
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BU of 3g32 by Molmil
CTX-M-9 class A beta-lactamase complexed with compound 6 (3G3)
分子名称: 2-[2-(1H-tetrazol-5-yl)ethyl]-1H-isoindole-1,3(2H)-dione, Beta-lactamase CTX-M-9a, DIMETHYL SULFOXIDE, ...
著者Chen, Y, Shoichet, B.K.
登録日2009-02-01
公開日2009-03-24
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.31 Å)
主引用文献Molecular docking and ligand specificity in fragment-based inhibitor discovery
Nat.Chem.Biol., 5, 2009
3G2Y
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BU of 3g2y by Molmil
CTX-M-9 class A beta-lactamase complexed with compound 1 (GF4)
分子名称: 4-ethyl-5-methyl-2-(1H-tetrazol-5-yl)-1,2-dihydro-3H-pyrazol-3-one, Beta-lactamase CTX-M-9a, DIMETHYL SULFOXIDE
著者Chen, Y, Shoichet, B.K.
登録日2009-02-01
公開日2009-03-24
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.31 Å)
主引用文献Molecular docking and ligand specificity in fragment-based inhibitor discovery
Nat.Chem.Biol., 5, 2009
3ITB
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BU of 3itb by Molmil
Crystal structure of Penicillin-Binding Protein 6 (PBP6) from E. coli in complex with a substrate fragment
分子名称: D-alanyl-D-alanine carboxypeptidase DacC, Peptidoglycan substrate (AMV)A(FGA)K(DAL)(DAL), SULFATE ION, ...
著者Chen, Y, Zhang, W, Shi, Q, Hesek, D, Lee, M, Mobashery, S, Shoichet, B.K.
登録日2009-08-27
公開日2009-10-20
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structures of penicillin-binding protein 6 from Escherichia coli.
J.Am.Chem.Soc., 131, 2009
3G35
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BU of 3g35 by Molmil
CTX-M-9 class A beta-lactamase complexed with compound 12 (F13)
分子名称: 3-fluoro-N-[3-(1H-tetrazol-5-yl)phenyl]benzamide, Beta-lactamase CTX-M-9a, DIMETHYL SULFOXIDE
著者Chen, Y, Shoichet, B.K.
登録日2009-02-01
公開日2009-03-24
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.41 Å)
主引用文献Molecular docking and ligand specificity in fragment-based inhibitor discovery
Nat.Chem.Biol., 5, 2009
6KI3
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BU of 6ki3 by Molmil
The crystal structure of AsfvAP:dF commplex
分子名称: DNA (5'-D(*CP*CP*TP*CP*GP*TP*CP*GP*GP*GP*GP*AP*CP*GP*CP*TP*G)-3'), DNA (5'-D(*GP*CP*AP*GP*CP*GP*TP*CP*C)-3'), DNA (5'-D(P*(3DR)P*CP*GP*AP*CP*GP*AP*G)-3'), ...
著者Chen, Y, Gan, J.
登録日2019-07-17
公開日2020-05-27
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.354 Å)
主引用文献A unique DNA-binding mode of African swine fever virus AP endonuclease.
Cell Discov, 6, 2020
8J3Z
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BU of 8j3z by Molmil
Cryo-EM structure of ATP-U46619-bound ABCC4
分子名称: (5Z)-7-{(1R,4S,5S,6R)-6-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2-oxabicyclo[2.2.1]hept-5-yl}hept-5-enoic acid, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 4, ...
著者Chen, Y, Wang, L, Hou, W.T, Zhou, C.Z, Chen, Y, Li, Q.
登録日2023-04-18
公開日2023-05-24
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.17 Å)
主引用文献Cryo-EM structure ofABCC4
Nat Cardiovasc Res, 2023
8J3W
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BU of 8j3w by Molmil
Cryo-EM structure of aspirin-bound ABCC4
分子名称: 2-(ACETYLOXY)BENZOIC ACID, ATP-binding cassette sub-family C member 4
著者Chen, Y, Wang, L, Hou, W.T, Zhou, C.Z, Chen, Y, Li, Q.
登録日2023-04-18
公開日2023-05-24
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.07 Å)
主引用文献Cryo-EM structure ofABCC4
Nat Cardiovasc Res, 2023
2P74
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BU of 2p74 by Molmil
CTX-M-9 class A beta-lactamase apo crystal structure at 0.88 Angstrom resolution
分子名称: Beta-lactamase CTX-M-9a, PHOSPHATE ION, POTASSIUM ION
著者Chen, Y, Bonnet, R, Shoichet, B.K.
登録日2007-03-19
公開日2007-04-24
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (0.88 Å)
主引用文献The Acylation Mechanism of CTX-M beta-Lactamase at 0.88 A Resolution.
J.Am.Chem.Soc., 129, 2007
6K28
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BU of 6k28 by Molmil
Crystal structure of the 5-(Hydroxyethyl)-methylthiazole Kinase ThiM from Klebsiella pneumonia in complex with TZE
分子名称: 2-(4-METHYL-THIAZOL-5-YL)-ETHANOL, Hydroxyethylthiazole kinase, MAGNESIUM ION
著者Chen, Y, Wang, L, Shang, F, Lan, J, Liu, W, Xu, Y.
登録日2019-05-13
公開日2019-07-10
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.002 Å)
主引用文献Structural insight of the 5-(Hydroxyethyl)-methylthiazole kinase ThiM involving vitamin B1 biosynthetic pathway from the Klebsiella pneumoniae.
Biochem.Biophys.Res.Commun., 518, 2019
6JYY
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BU of 6jyy by Molmil
Crystal structure of the 5-(Hydroxyethyl)-methylthiazole Kinase ThiM from Klebsiella pneumonia
分子名称: Hydroxyethylthiazole kinase
著者Chen, Y, Wang, L, Shang, F, Lan, J, Liu, W, Xu, Y.
登録日2019-04-29
公開日2019-06-26
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural insight of the 5-(Hydroxyethyl)-methylthiazole kinase ThiM involving vitamin B1 biosynthetic pathway from the Klebsiella pneumoniae.
Biochem.Biophys.Res.Commun., 518, 2019
3M9E
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BU of 3m9e by Molmil
Thyroid hormone beta DNA binding domain homodimer with inverted palindrome TRE
分子名称: DNA (5'-D(*AP*TP*TP*GP*AP*CP*CP*TP*CP*AP*GP*CP*TP*GP*AP*GP*GP*TP*CP*AP*AP*T)-3'), Thyroid hormone receptor beta, ZINC ION
著者Chen, Y.
登録日2010-03-22
公開日2010-08-18
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.406 Å)
主引用文献Structure of a thyroid hormone receptor DNA-binding domain homodimer bound to an inverted palindrome DNA response element.
Mol.Endocrinol., 24, 2010
8GV5
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BU of 8gv5 by Molmil
Crystal structure of PN-SIA28 in complex with influenza hemagglutinin A/swine/Guangdong/104/2013 (H1N1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, Hemagglutinin HA2 chain, ...
著者Chen, Y, Song, H, Qi, J, Gao, G.F.
登録日2022-09-14
公開日2022-12-21
最終更新日2024-11-20
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis for a human broadly neutralizing influenza A hemagglutinin stem-specific antibody including H17/18 subtypes.
Nat Commun, 13, 2022
8Z1E
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A homotrimeric GPCR architecture of the human cytomegalovirus (UL78) revealed by cryo-EM
分子名称: Uncharacterized protein UL78
著者Chen, Y, Li, Y, Zhou, Q, Cong, Z, Lin, S, Yan, J, Chen, X, Yang, D, Ying, T, Wang, M.-W.
登録日2024-04-11
公開日2024-05-15
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (3.12 Å)
主引用文献A homotrimeric GPCR architecture of the human cytomegalovirus revealed by cryo-EM.
Cell Discov, 10, 2024
8GV6
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Crystal structure of PN-SIA28 in complex with influenza hemagglutinin H14 (A/long-tailed duck/Wisconsin/10OS3912/2010)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin H14-HA1, ...
著者Chen, Y, Song, H, Qi, J, Gao, G.F.
登録日2022-09-14
公開日2022-12-21
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structural basis for a human broadly neutralizing influenza A hemagglutinin stem-specific antibody including H17/18 subtypes.
Nat Commun, 13, 2022

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