3ITA
Crystal structure of Penicillin-Binding Protein 6 (PBP6) from E. coli in acyl-enzyme complex with ampicillin
Summary for 3ITA
Entry DOI | 10.2210/pdb3ita/pdb |
Related | 3IT9 3ITB |
Descriptor | D-alanyl-D-alanine carboxypeptidase dacC, (2R,4S)-2-[(1R)-1-{[(2R)-2-amino-2-phenylacetyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, SULFATE ION, ... (5 entities in total) |
Functional Keywords | ppenicillin-binding protein, bp6, dd-carboxypeptidase, peptidoglycan, ampicillin, acyl-enzyme complex, carboxypeptidase, cell inner membrane, cell membrane, cell shape, cell wall biogenesis/degradation, hydrolase, membrane, peptidoglycan synthesis, protease |
Biological source | Escherichia coli |
Cellular location | Cell inner membrane ; Peripheral membrane protein ; Periplasmic side : P08506 |
Total number of polymer chains | 4 |
Total formula weight | 153642.41 |
Authors | Chen, Y.,Zhang, W.,Shi, Q.,Hesek, D.,Lee, M.,Mobashery, S.,Shoichet, B.K. (deposition date: 2009-08-27, release date: 2009-10-20, Last modification date: 2024-04-03) |
Primary citation | Chen, Y.,Zhang, W.,Shi, Q.,Hesek, D.,Lee, M.,Mobashery, S.,Shoichet, B.K. Crystal structures of penicillin-binding protein 6 from Escherichia coli. J.Am.Chem.Soc., 131:14345-14354, 2009 Cited by PubMed: 19807181DOI: 10.1021/ja903773f PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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