3ITB

Crystal structure of Penicillin-Binding Protein 6 (PBP6) from E. coli in complex with a substrate fragment

Summary for 3ITB

Entry DOI	10.2210/pdb3itb/pdb
Related	3IT9 3ITA
Related PRD ID	PRD_900003
Descriptor	D-alanyl-D-alanine carboxypeptidase DacC, Peptidoglycan substrate (AMV)A(FGA)K(DAL)(DAL), beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, ... (6 entities in total)
Functional Keywords	penicillin-binding protein, pbp6, dd-carboxypeptidase, peptidoglycan, substrate fragment, carboxypeptidase, cell inner membrane, cell membrane, cell shape, cell wall biogenesis/degradation, hydrolase, membrane, peptidoglycan synthesis, protease
Biological source	Escherichia coli More
Cellular location	Cell inner membrane ; Peripheral membrane protein ; Periplasmic side : P08506
Total number of polymer chains	5
Total formula weight	154080.72
Authors	Chen, Y.,Zhang, W.,Shi, Q.,Hesek, D.,Lee, M.,Mobashery, S.,Shoichet, B.K. (deposition date: 2009-08-27, release date: 2009-10-20, Last modification date: 2024-04-03)
Primary citation	Chen, Y.,Zhang, W.,Shi, Q.,Hesek, D.,Lee, M.,Mobashery, S.,Shoichet, B.K. Crystal structures of penicillin-binding protein 6 from Escherichia coli. J.Am.Chem.Soc., 131:14345-14354, 2009 Cited by PubMed: 19807181 DOI: 10.1021/ja903773f PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation