3ITB

Crystal structure of Penicillin-Binding Protein 6 (PBP6) from E. coli in complex with a substrate fragment

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000270	biological_process	peptidoglycan metabolic process
A	0004180	molecular_function	carboxypeptidase activity
A	0005886	cellular_component	plasma membrane
A	0006508	biological_process	proteolysis
A	0008233	molecular_function	peptidase activity
A	0008360	biological_process	regulation of cell shape
A	0008658	molecular_function	penicillin binding
A	0009002	molecular_function	serine-type D-Ala-D-Ala carboxypeptidase activity
A	0009252	biological_process	peptidoglycan biosynthetic process
A	0009410	biological_process	response to xenobiotic stimulus
A	0016787	molecular_function	hydrolase activity
A	0030288	cellular_component	outer membrane-bounded periplasmic space
A	0042803	molecular_function	protein homodimerization activity
A	0071555	biological_process	cell wall organization
B	0000270	biological_process	peptidoglycan metabolic process
B	0004180	molecular_function	carboxypeptidase activity
B	0005886	cellular_component	plasma membrane
B	0006508	biological_process	proteolysis
B	0008233	molecular_function	peptidase activity
B	0008360	biological_process	regulation of cell shape
B	0008658	molecular_function	penicillin binding
B	0009002	molecular_function	serine-type D-Ala-D-Ala carboxypeptidase activity
B	0009252	biological_process	peptidoglycan biosynthetic process
B	0009410	biological_process	response to xenobiotic stimulus
B	0016787	molecular_function	hydrolase activity
B	0030288	cellular_component	outer membrane-bounded periplasmic space
B	0042803	molecular_function	protein homodimerization activity
B	0071555	biological_process	cell wall organization
C	0000270	biological_process	peptidoglycan metabolic process
C	0004180	molecular_function	carboxypeptidase activity
C	0005886	cellular_component	plasma membrane
C	0006508	biological_process	proteolysis
C	0008233	molecular_function	peptidase activity
C	0008360	biological_process	regulation of cell shape
C	0008658	molecular_function	penicillin binding
C	0009002	molecular_function	serine-type D-Ala-D-Ala carboxypeptidase activity
C	0009252	biological_process	peptidoglycan biosynthetic process
C	0009410	biological_process	response to xenobiotic stimulus
C	0016787	molecular_function	hydrolase activity
C	0030288	cellular_component	outer membrane-bounded periplasmic space
C	0042803	molecular_function	protein homodimerization activity
C	0071555	biological_process	cell wall organization
D	0000270	biological_process	peptidoglycan metabolic process
D	0004180	molecular_function	carboxypeptidase activity
D	0005886	cellular_component	plasma membrane
D	0006508	biological_process	proteolysis
D	0008233	molecular_function	peptidase activity
D	0008360	biological_process	regulation of cell shape
D	0008658	molecular_function	penicillin binding
D	0009002	molecular_function	serine-type D-Ala-D-Ala carboxypeptidase activity
D	0009252	biological_process	peptidoglycan biosynthetic process
D	0009410	biological_process	response to xenobiotic stimulus
D	0016787	molecular_function	hydrolase activity
D	0030288	cellular_component	outer membrane-bounded periplasmic space
D	0042803	molecular_function	protein homodimerization activity
D	0071555	biological_process	cell wall organization

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Active site: {"description":"Acyl-ester intermediate","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	4
Details	Active site: {"description":"Proton acceptor","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Active site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	4
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	4
Details	Annotated By Reference To The Literature 1btl

Chain	Residue	Details
A	SER106
A	SER40
A	LYS43
A	GLN144

---

site_id	CSA2
Number of Residues	4
Details	Annotated By Reference To The Literature 1btl

Chain	Residue	Details
B	SER106
B	SER40
B	LYS43
B	GLN144

---

site_id	CSA3
Number of Residues	4
Details	Annotated By Reference To The Literature 1btl

Chain	Residue	Details
C	SER106
C	SER40
C	LYS43
C	GLN144

---

site_id	CSA4
Number of Residues	4
Details	Annotated By Reference To The Literature 1btl

Chain	Residue	Details
D	SER106
D	SER40
D	LYS43
D	GLN144

---