5IM5
 
 | | Crystal structure of designed two-component self-assembling icosahedral cage I53-40 | | 分子名称: | Designed Keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase, Designed Riboflavin synthase | | 著者 | Liu, Y.A, Cascio, D, Sawaya, M.R, Bale, J.B, Collazo, M.J, Thomas, C, Sheffler, W, King, N.P, Baker, D, Yeates, T.O. | | 登録日 | 2016-03-05 | | 公開日 | 2016-07-27 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.699 Å) | | 主引用文献 | Accurate design of megadalton-scale two-component icosahedral protein complexes.
Science, 353, 2016
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5K7P
 | | MicroED structure of xylanase at 2.3 A resolution | | 分子名称: | Endo-1,4-beta-xylanase 2, IODIDE ION | | 著者 | de la Cruz, M.J, Hattne, J, Shi, D, Seidler, P, Rodriguez, J, Reyes, F.E, Sawaya, M.R, Cascio, D, Eisenberg, D, Gonen, T. | | 登録日 | 2016-05-26 | | 公開日 | 2017-04-05 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (2.3 Å) | | 主引用文献 | Atomic-resolution structures from fragmented protein crystals with the cryoEM method MicroED.
Nat. Methods, 14, 2017
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3DGJ
 | | NNFGAIL segment from Islet Amyloid Polypeptide (IAPP or amylin) | | 分子名称: | NNFGAIL peptide | | 著者 | Wiltzius, J.J, Sievers, S.A, Sawaya, M.R, Cascio, D, Eisenberg, D. | | 登録日 | 2008-06-13 | | 公開日 | 2008-07-01 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Atomic structure of the cross-beta spine of islet amyloid polypeptide (amylin).
Protein Sci., 17, 2008
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5IM4
 | | Crystal structure of designed two-component self-assembling icosahedral cage I52-32 | | 分子名称: | 6,7-dimethyl-8-ribityllumazine synthase, Phosphotransferase system, mannose/fructose-specific component IIA | | 著者 | Liu, Y.A, Cascio, D, Sawaya, M.R, Bale, J.B, Collazo, M.J, Thomas, C, Sheffler, W, King, N.P, Baker, D, Yeates, T.O. | | 登録日 | 2016-03-05 | | 公開日 | 2016-07-27 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Accurate design of megadalton-scale two-component icosahedral protein complexes.
Science, 353, 2016
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5IM6
 | | Crystal structure of designed two-component self-assembling icosahedral cage I32-28 | | 分子名称: | Designed self-assembling icosahedral cage I32-28 dimeric subunit, Designed self-assembling icosahedral cage I32-28 trimeric subunit | | 著者 | Liu, Y.A, Cascio, D, Sawaya, M.R, Bale, J.B, Collazo, M.J, Thomas, C, Sheffler, W, King, N.P, Baker, D, Yeates, T.O. | | 登録日 | 2016-03-05 | | 公開日 | 2016-07-27 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (5.588 Å) | | 主引用文献 | Accurate design of megadalton-scale two-component icosahedral protein complexes.
Science, 353, 2016
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3DG1
 | | Segment SSTNVG derived from IAPP | | 分子名称: | SSTNVG from Islet Amyloid Polypeptide | | 著者 | Wiltzius, J.J, Sievers, S.A, Sawaya, M.R, Cascio, D, Eisenberg, D. | | 登録日 | 2008-06-12 | | 公開日 | 2008-07-01 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | | 主引用文献 | Atomic structure of the cross-beta spine of islet amyloid polypeptide (amylin).
Protein Sci., 17, 2008
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126D
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5KO0
 | | Human Islet Amyloid Polypeptide Segment 15-FLVHSSNNFGA-25 Determined by MicroED | | 分子名称: | THIOCYANATE ION, hIAPP(15-25)WT | | 著者 | Krotee, P.A.L, Rodriguez, J.A, Sawaya, M.R, Cascio, D, Shi, D, Nannenga, B.L, Hattne, J, Reyes, F.E, Gonen, T, Eisenberg, D.S. | | 登録日 | 2016-06-28 | | 公開日 | 2016-12-21 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1.4 Å) | | 主引用文献 | Atomic structures of fibrillar segments of hIAPP suggest tightly mated beta-sheets are important for cytotoxicity.
Elife, 6, 2017
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5KNZ
 | | Human Islet Amyloid Polypeptide Segment 19-SGNNFGAILSS-29 with Early Onset S20G Mutation Determined by MicroED | | 分子名称: | hIAPP(residues 19-29)S20G | | 著者 | Krotee, P.A.L, Rodriguez, J.A, Sawaya, M.R, Cascio, D, Shi, D, Nannenga, B.L, Hattne, J, Reyes, F.E, Gonen, T, Eisenberg, D.S. | | 登録日 | 2016-06-28 | | 公開日 | 2016-12-21 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1.9 Å) | | 主引用文献 | Atomic structures of fibrillar segments of hIAPP suggest tightly mated beta-sheets are important for cytotoxicity.
Elife, 6, 2017
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158D
 | | CRYSTALLOGRAPHIC ANALYSIS OF C-C-A-A-G-C-T-T-G-G AND ITS IMPLICATIONS FOR BENDING IN B-DNA | | 分子名称: | CALCIUM ION, DNA (5'-D(*CP*CP*AP*AP*GP*CP*TP*TP*GP*G)-3') | | 著者 | Grzeskowiak, K, Goodsell, D.S, Kaczor-Grzeskowiak, M, Cascio, D, Dickerson, R.E. | | 登録日 | 1994-02-03 | | 公開日 | 1994-05-31 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystallographic analysis of C-C-A-A-G-C-T-T-G-G and its implications for bending in B-DNA.
Biochemistry, 32, 1993
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1A04
 | | THE STRUCTURE OF THE NITRATE/NITRITE RESPONSE REGULATOR PROTEIN NARL IN THE MONOCLINIC C2 CRYSTAL FORM | | 分子名称: | NITRATE/NITRITE RESPONSE REGULATOR PROTEIN NARL | | 著者 | Baikalov, I, Schroder, I, Kaczor-Grzeskowiak, M, Cascio, D, Gunsalus, R.P, Dickerson, R.E. | | 登録日 | 1997-12-08 | | 公開日 | 1998-03-18 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | NarL dimerization? Suggestive evidence from a new crystal form
Biochemistry, 37, 1998
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3DBO
 | | Crystal structure of a member of the VapBC family of toxin-antitoxin systems, VapBC-5, from Mycobacterium tuberculosis | | 分子名称: | ACETATE ION, BETA-MERCAPTOETHANOL, SODIUM ION, ... | | 著者 | Miallau, L, Cascio, D, Eisenberg, D, Integrated Center for Structure and Function Innovation (ISFI), TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2008-06-02 | | 公開日 | 2008-07-15 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | Structure and Proposed Activity of a Member of the VapBC Family of Toxin-Antitoxin Systems: VapBC-5 FROM MYCOBACTERIUM TUBERCULOSIS.
J.Biol.Chem., 284, 2009
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2IBP
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5HS0
 | | Computationally Designed Cyclic Tetramer ank1C4_7 | | 分子名称: | Ankyrin domain protein ank1C4_7, GLYCEROL, SULFATE ION | | 著者 | McNamara, D.E, Cascio, D, Fallas, J.A, Baker, D, Yeates, T.O. | | 登録日 | 2016-01-24 | | 公開日 | 2017-04-12 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Computational design of self-assembling cyclic protein homo-oligomers.
Nat Chem, 9, 2017
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2IEF
 | | Structure of the cooperative Excisionase (Xis)-DNA complex reveals a micronucleoprotein filament | | 分子名称: | 15-mer DNA, 19-mer DNA, 34-mer DNA, ... | | 著者 | Abbani, M.A, Papagiannis, C.V, Sam, M.D, Cascio, D, Johnson, R.C, Clubb, R.T. | | 登録日 | 2006-09-18 | | 公開日 | 2007-02-06 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.601 Å) | | 主引用文献 | Structure of the cooperative Xis-DNA complex reveals a micronucleoprotein filament that regulates phage lambda intasome assembly.
Proc.Natl.Acad.Sci.Usa, 104, 2007
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2IGC
 | | Structure of Spin labeled T4 Lysozyme Mutant T115R1A | | 分子名称: | Lysozyme, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate | | 著者 | Guo, Z, Cascio, D, Hideg, K, Hubbell, W.L. | | 登録日 | 2006-09-22 | | 公開日 | 2007-06-12 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Structural determinants of nitroxide motion in spin-labeled proteins: Tertiary contact and solvent-inaccessible sites in helix G of T4 lysozyme.
Protein Sci., 16, 2007
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1PK1
 | | Hetero SAM domain structure of Ph and Scm. | | 分子名称: | Polyhomeotic-proximal chromatin protein, Sex comb on midleg CG9495-PA | | 著者 | Kim, C.A, Sawaya, M.R, Cascio, D, Kim, W, Bowie, J.U. | | 登録日 | 2003-06-04 | | 公開日 | 2005-02-15 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural organization of a Sex-comb-on-midleg/polyhomeotic copolymer.
J.Biol.Chem., 280, 2005
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1PK3
 | | Scm SAM domain | | 分子名称: | BETA-MERCAPTOETHANOL, Sex comb on midleg CG9495-PA | | 著者 | Kim, C.A, Sawaya, M.R, Cascio, D, Kim, W, Bowie, J.U. | | 登録日 | 2003-06-04 | | 公開日 | 2005-02-15 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural organization of a Sex-comb-on-midleg/polyhomeotic copolymer.
J.Biol.Chem., 280, 2005
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1MY6
 | | The 1.6 A Structure of Fe-Superoxide Dismutase from the thermophilic cyanobacterium Thermosynechococcus elongatus : Correlation of EPR and Structural Characteristics | | 分子名称: | FE (III) ION, Iron (III) Superoxide Dismutase | | 著者 | Yoshida, S.M, Cascio, D, Sawaya, M.R, Yeates, T.O, Kerfeld, C.A. | | 登録日 | 2002-10-03 | | 公開日 | 2003-07-29 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The 1.6 A resolution structure of Fe-superoxide dismutase from the thermophilic cyanobacterium Thermosynechococcus elongatus.
J.BIOL.INORG.CHEM., 8, 2003
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2HUL
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2HUK
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2HUM
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4M5S
 | | Human alphaB crystallin core domain in complex with C-terminal peptide | | 分子名称: | Alpha-crystallin B chain, SUCCINIC ACID | | 著者 | Laganowsky, A, Cascio, D, Sawaya, M.R, Eisenberg, D. | | 登録日 | 2013-08-08 | | 公開日 | 2014-04-09 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | | 主引用文献 | The structured core domain of alpha B-crystallin can prevent amyloid fibrillation and associated toxicity.
Proc.Natl.Acad.Sci.USA, 111, 2014
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5K2H
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5K2F
 | | Structure of NNQQNY from yeast prion Sup35 with cadmium acetate determined by MicroED | | 分子名称: | ACETATE ION, CADMIUM ION, Eukaryotic peptide chain release factor GTP-binding subunit | | 著者 | Rodriguez, J.A, Sawaya, M.R, Cascio, D, Eisenberg, D.S. | | 登録日 | 2016-05-18 | | 公開日 | 2016-09-14 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1 Å) | | 主引用文献 | Ab initio structure determination from prion nanocrystals at atomic resolution by MicroED.
Proc.Natl.Acad.Sci.USA, 113, 2016
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