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7JMO
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BU of 7jmo by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody COVA2-04
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, COVA2-04 heavy chain, COVA2-04 light chain, ...
著者Wu, N.C, Yuan, M, Liu, H, Zhu, X, Wilson, I.A.
登録日2020-08-02
公開日2020-08-26
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.359 Å)
主引用文献An Alternative Binding Mode of IGHV3-53 Antibodies to the SARS-CoV-2 Receptor Binding Domain.
Cell Rep, 33, 2020
7JMP
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BU of 7jmp by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody COVA2-39
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, COVA2-39 heavy chain, COVA2-39 light chain, ...
著者Wu, N.C, Yuan, M, Liu, H, Zhu, X, Wilson, I.A.
登録日2020-08-02
公開日2020-08-26
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.712 Å)
主引用文献An Alternative Binding Mode of IGHV3-53 Antibodies to the SARS-CoV-2 Receptor Binding Domain.
Cell Rep, 33, 2020
7JTG
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BU of 7jtg by Molmil
Structure of Hepatitis C Virus Envelope Glycoprotein E2 core from genotype 6a bound to broadly neutralizing antibody RM11-43
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein E2, ...
著者Tzarum, N, Wilson, I.A, Law, M.
登録日2020-08-17
公開日2021-03-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献HCV Env immunization elicits a rapid VH1-69-like broadly neutralizing antibody response in rhesus macaques
Immunity, 2021
7JTF
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BU of 7jtf by Molmil
Structure of Hepatitis C Virus Envelope Glycoprotein E2 core from genotype 6a bound to broadly neutralizing antibody RM2-01
分子名称: Envelope glycoprotein E2, RM2-01 Fab heavy chain, RM2-01 Fab light chain
著者Tzarum, N, Wilson, I.A, Law, M.
登録日2020-08-17
公開日2021-03-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献HCV Env immunization elicits a rapid VH1-69-like broadly neutralizing antibody response in rhesus macaques
Immunity, 2021
7JPH
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BU of 7jph by Molmil
Crystal structure of EBOV glycoprotein with modified HR1c and HR2 stalk at 3.2 A resolution
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein, ...
著者Chaudhary, A, Stanfield, R.L, Wilson, I.A, Zhu, J.
登録日2020-08-08
公開日2021-04-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.195 Å)
主引用文献Single-component multilayered self-assembling nanoparticles presenting rationally designed glycoprotein trimers as Ebola virus vaccines.
Nat Commun, 12, 2021
7JPI
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BU of 7jpi by Molmil
Crystal structure of EBOV glycoprotein with modified HR2 stalk at 2.3A resolution
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein, ...
著者Chaudhary, A, Stanfield, R.L, Wilson, I.A, Zhu, J.
登録日2020-08-08
公開日2021-04-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Single-component multilayered self-assembling nanoparticles presenting rationally designed glycoprotein trimers as Ebola virus vaccines.
Nat Commun, 12, 2021
7K75
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BU of 7k75 by Molmil
Crystal structure of MAD2-6 IgA Fab in complex with PfCSP N-terminal peptide.
分子名称: Heavy chain of MAD2-6 IgA Fab, Light chain of MAD2-6 IgA Fab, PfCSP N-terminal peptide P17
著者Pholcharee, T, Wilson, I.A.
登録日2020-09-22
公開日2021-06-23
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Functional human IgA targets a conserved site on malaria sporozoites.
Sci Transl Med, 13, 2021
7K76
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BU of 7k76 by Molmil
Crystal structure of MAD2-6 IgG Fab in complex with PfCSP N-terminal peptide.
分子名称: Heavy chain of MAD2-6 IgG Fab, Light chain of MAD2-6 IgG Fab, PfCSP N-terminal peptide P17
著者Pholcharee, T, Wilson, I.A.
登録日2020-09-22
公開日2021-06-23
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Functional human IgA targets a conserved site on malaria sporozoites.
Sci Transl Med, 13, 2021
6E7G
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BU of 6e7g by Molmil
Crystal structure of H5 hemagglutinin mutant Y161A from A/Viet Nam/1203/2004 H5N1 influenza virus
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
著者Tzarum, N, Wilson, I.A.
登録日2018-07-26
公開日2019-06-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.094 Å)
主引用文献N-Glycolylneuraminic Acid as a Receptor for Influenza A Viruses.
Cell Rep, 27, 2019
6E7H
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BU of 6e7h by Molmil
Crystal structure of H5 hemagglutinin mutant Y161A from A/Viet Nam/1203/2004 H5N1 influenza virus in complex with 3'-GcLN
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
著者Tzarum, N, Wilson, I.A.
登録日2018-07-26
公開日2019-06-19
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献N-Glycolylneuraminic Acid as a Receptor for Influenza A Viruses.
Cell Rep, 27, 2019
1CD1
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BU of 1cd1 by Molmil
CD1(MOUSE) ANTIGEN PRESENTING MOLECULE
分子名称: CD1
著者Zeng, Z.H, Segelke, B.W, Wilson, I.A.
登録日1997-04-02
公開日1997-10-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.67 Å)
主引用文献Crystal structure of mouse CD1: An MHC-like fold with a large hydrophobic binding groove.
Science, 277, 1997
1D5T
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BU of 1d5t by Molmil
GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR, ALPHA-ISOFORM
分子名称: GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR, SULFATE ION
著者Peng, L, Zeng, K, Heine, A, Moyer, B, Greasley, S.E, Kuhn, P, Balch, W.E, Wilson, I.A.
登録日1999-10-11
公開日2000-10-25
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.04 Å)
主引用文献A new functional domain of guanine nucleotide dissociation inhibitor (alpha-GDI) involved in Rab recycling.
Traffic, 1, 2000
3V47
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BU of 3v47 by Molmil
Crystal structure of the N-terminal fragment of zebrafish TLR5 in complex with Salmonella flagellin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Flagellin, ...
著者Yoon, S.I, Hong, H, Wilson, I.A.
登録日2011-12-14
公開日2012-02-29
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.47 Å)
主引用文献Structural basis of TLR5-flagellin recognition and signaling.
Science, 335, 2012
6FYT
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BU of 6fyt by Molmil
Structure of H1 (A/solomon Islands/3/06) Influenza Hemagglutinin in complex with SD38
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
著者Laursen, N.S, Wilson, I.A.
登録日2018-03-12
公開日2018-11-07
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin.
Science, 362, 2018
3UN9
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BU of 3un9 by Molmil
Crystal structure of an immune receptor
分子名称: NLR family member X1, PLATINUM (II) ION
著者Hong, M, Yoon, S.I, Wilson, I.A.
登録日2011-11-15
公開日2012-03-28
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structure and Functional Characterization of the RNA-Binding Element of the NLRX1 Innate Immune Modulator.
Immunity, 36, 2012
6FYW
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BU of 6fyw by Molmil
Structure of B/Brisbane/60/2008 Influenza Hemagglutinin in complex with SD83
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
著者Laursen, N.S, Wilson, I.A.
登録日2018-03-12
公開日2018-11-07
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin.
Science, 362, 2018
6FYU
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BU of 6fyu by Molmil
Structure of H7(A/Shanghai/2/2013) Influenza Hemagglutinin in complex SD36
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
著者Laursen, N.S, Wilson, I.A.
登録日2018-03-12
公開日2018-11-07
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.643 Å)
主引用文献Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin.
Science, 362, 2018
3V44
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BU of 3v44 by Molmil
Crystal structure of the N-terminal fragment of zebrafish TLR5
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Toll-like receptor 5b and variable lymphocyte receptor B.61 chimeric protein
著者Yoon, S.I, Hong, H, Wilson, I.A.
登録日2011-12-14
公開日2012-02-29
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.83 Å)
主引用文献Structural basis of TLR5-flagellin recognition and signaling.
Science, 335, 2012
6FYS
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BU of 6fys by Molmil
Structure of single domain antibody SD83
分子名称: 1,2-ETHANEDIOL, Single domain antibody SD83
著者Laursen, N.S, Wilson, I.A.
登録日2018-03-12
公開日2018-11-07
最終更新日2022-03-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin.
Science, 362, 2018
5KUX
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BU of 5kux by Molmil
Designed influenza hemagglutinin binding protein HSB.2
分子名称: Designed influenza inhibitor protein HSB.2
著者Lee, P.S, Bernard, S.M, Wilson, I.A.
登録日2016-07-13
公開日2017-06-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Computational design of trimeric influenza-neutralizing proteins targeting the hemagglutinin receptor binding site.
Nat. Biotechnol., 35, 2017
5KUY
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BU of 5kuy by Molmil
Influenza hemagglutinin H3 A/Hong Kong/1/1968 in complex with designed inhibitor protein HSB.2A
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Designed influenza inhibitor HSB.2A, ...
著者Bernard, S.M, Wilson, I.A.
登録日2016-07-13
公開日2017-06-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.598 Å)
主引用文献Computational design of trimeric influenza-neutralizing proteins targeting the hemagglutinin receptor binding site.
Nat. Biotechnol., 35, 2017
7T7B
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BU of 7t7b by Molmil
Crystal structure of SARS-CoV-2 spike protein receptor-binding domain in complex with a cross-neutralizing antibody ADI-62113 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ADI-62113 Fab heavy chain, ADI-62113 Fab light chain, ...
著者Liu, H, Wilson, I.A.
登録日2021-12-14
公開日2022-08-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Human antibodies to SARS-CoV-2 with a recurring YYDRxG motif retain binding and neutralization to variants of concern including Omicron.
Commun Biol, 5, 2022
7TP3
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BU of 7tp3 by Molmil
Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody K288.2
分子名称: CACODYLATE ION, K288.2 heavy chain, K288.2 light chain, ...
著者Yuan, M, Zhu, X, Wilson, I.A.
登録日2022-01-24
公開日2022-02-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques.
Sci Transl Med, 14, 2022
7TP4
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Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody K398.22
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, K398.22 heavy chain, ...
著者Yuan, M, Zhu, X, Wilson, I.A.
登録日2022-01-24
公開日2022-02-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques.
Sci Transl Med, 14, 2022
7U8L
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BU of 7u8l by Molmil
Crystal structure of chimeric hemagglutinin cH15/3 in complex with broad protective antibody 31.a.83
分子名称: Antibody Fab light chain, Hemagglutinin HA1 subunit, Hemagglutinin HA2 subunit, ...
著者Zhu, X, Wilson, I.A.
登録日2022-03-08
公開日2022-06-08
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (4.56 Å)
主引用文献Influenza chimeric hemagglutinin structures in complex with broadly protective antibodies to the stem and trimer interface.
Proc.Natl.Acad.Sci.USA, 119, 2022

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