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8C0E
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BU of 8c0e by Molmil
The lipid linked oligosaccharide polymerase Wzy and its regulating co-polymerase Wzz form a complex in vivo and in vitro
分子名称: ECA polysaccharide chain length modulation protein
著者Weckener, M, Woodward, L.S, Clarke, B.R, Liu, H, Ward, P.N, Le Bas, A, Bhella, D, Whitfield, C, Naismith, J.H.
登録日2022-12-16
公開日2023-04-19
最終更新日2025-07-09
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献The lipid linked oligosaccharide polymerase Wzy and its regulating co-polymerase, Wzz, from enterobacterial common antigen biosynthesis form a complex.
Open Biology, 13, 2023
8BSO
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BU of 8bso by Molmil
crystal structure of antibody Fab with SiaLac-amidine-Lys
分子名称: (2~{S})-2-acetamido-6-(2-sulfanylethanimidoylamino)hexanamide, BAR-1 Fab heavy chain, BAR-1 Fab light chain, ...
著者Moynie, L, Naismith, J.H.
登録日2022-11-25
公開日2023-09-27
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献crystal structure of antibody Fab with SiaLac-amidine-Lys
To Be Published
2V7X
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BU of 2v7x by Molmil
X-RAY CRYSTAL STRUCTURE OF 5'-FLUORODEOXYADENOSINE SYNTHASE S158A mutant FROM STREPTOMYCES CATTLEYA COMPLEXED WITH the PRODUCTS, FDA and Met
分子名称: 5'-FLUORO-5'-DEOXYADENOSINE, 5'-FLUORO-5'-DEOXYADENOSINE SYNTHASE, METHIONINE
著者Robinson, D.A, Zhu, X, O'Hagan, D, Naismith, J.H.
登録日2007-08-02
公開日2008-08-12
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Mechanism of enzymatic fluorination in Streptomyces cattleya.
J. Am. Chem. Soc., 129, 2007
2V7W
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BU of 2v7w by Molmil
X-ray crystal structure of 5'-fluorodeoxyadenosine synthase s158g mutant complexed with 5'-fluorodeoxyadenosin
分子名称: 5'-FLUORO-5'-DEOXYADENOSINE, 5'-FLUORO-5'-DEOXYADENOSINE SYNTHASE
著者Zhu, X, O'Hagan, D, Naismith, J.H.
登録日2007-08-02
公開日2008-08-12
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Mechanism of enzymatic fluorination in Streptomyces cattleya.
J. Am. Chem. Soc., 129, 2007
2V7V
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X-ray crystal structure of 5'-fluorodeoxyadenosine synthase from streptomyces cattleya complexed with 5'-fluorodeoxyadenosine
分子名称: 5'-FLUORO-5'-DEOXYADENOSINE, 5'-FLUORO-5'-DEOXYADENOSINE SYNTHASE
著者Zhu, X, O'Hagan, D, Naismith, J.H.
登録日2007-08-02
公開日2008-08-12
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Mechanism of enzymatic fluorination in Streptomyces cattleya.
J. Am. Chem. Soc., 129, 2007
2V7T
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BU of 2v7t by Molmil
X-ray crystal structure of 5'-fluorodeoxyadenosine synthase s158g mutant complexed with s-adenosyl-l-homocysteine and chloride ion
分子名称: 5'-FLUORO-5'-DEOXYADENOSINE SYNTHASE, CHLORIDE ION, S-ADENOSYL-L-HOMOCYSTEINE
著者Zhu, X, O'Hagan, D, Naismith, J.H.
登録日2007-08-01
公開日2008-08-12
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Mechanism of enzymatic fluorination in Streptomyces cattleya.
J. Am. Chem. Soc., 129, 2007
2V7U
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BU of 2v7u by Molmil
X-ray crystal structure of 5'-fluorodeoxyadenosine synthase s158g mutant complexed with s-adenosylmethionine and chloride ion
分子名称: 5'-FLUORO-5'-DEOXY ADENOSINE SYNTHETASE, CHLORIDE ION, S-ADENOSYLMETHIONINE
著者Zhu, X, O'Hagan, D, Naismith, J.H.
登録日2007-08-02
公開日2008-08-12
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Mechanism of enzymatic fluorination in Streptomyces cattleya.
J. Am. Chem. Soc., 129, 2007
8OYT
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BU of 8oyt by Molmil
Stabilised BA.1 SARS-CoV-2 spike with H6 nanobodies in '3 up' RBD conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, H6 nanobody, ...
著者Weckener, M, Naismith, J.H, Owens, R.J.
登録日2023-05-05
公開日2024-07-03
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural and functional characterization of nanobodies that neutralize Omicron variants of SARS-CoV-2.
Open Biology, 14, 2024
8OWT
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BU of 8owt by Molmil
SARS-CoV-2 spike RBD with A8 and H3 nanobodies bound
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody A8, ...
著者Mikolajek, H, Naismith, J.H, Owens, R.J.
登録日2023-04-28
公開日2024-05-08
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Structural and functional characterization of nanobodies that neutralize Omicron variants of SARS-CoV-2.
Open Biology, 14, 2024
8OWW
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BU of 8oww by Molmil
B5-5 nanobody bound to SARS-CoV-2 spike RBD (Wuhan)
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, B5-5 nanobody, ...
著者Cornish, K.A.S, Naismith, J.H, Owens, R.J.
登録日2023-04-28
公開日2024-05-08
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.969 Å)
主引用文献Structural and functional characterization of nanobodies that neutralize Omicron variants of SARS-CoV-2.
Open Biology, 14, 2024
8OWV
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BU of 8owv by Molmil
H6 and F2 nanobodies bound to SARS-CoV-2 spike RBD
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, F2, GLYCEROL, ...
著者Mikolajek, H, Naismith, J.H, Owens, R.J.
登録日2023-04-28
公開日2024-05-08
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Structural and functional characterization of nanobodies that neutralize Omicron variants of SARS-CoV-2.
Open Biology, 14, 2024
8OYU
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BU of 8oyu by Molmil
Stabilised BA.1 SARS-CoV-2 spike with H6 nanobodies in '2 up 1 down' RBD conformation
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, H6 nanobody, ...
著者Weckener, M, Naismith, J.H, Owens, R.J.
登録日2023-05-05
公開日2024-05-15
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structural and functional characterization of nanobodies that neutralize Omicron variants of SARS-CoV-2.
Open Biology, 14, 2024
6Q5E
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BU of 6q5e by Molmil
Crystal structure of the ferric enterobactin receptor from Pseudomonas aeruginosa (PfeA) in complex with enterobactin
分子名称: (R)-((2R,3S,4R,5R,6R)-3-HYDROXY-2-(HYDROXYMETHYL)-5-((R)-3-HYDROXYTETRADECANAMIDO)-6-(PHOSPHONOOXY)TETRAHYDRO-2H-PYRAN-4-YL) 3-HYDROXYTETRADECANOATE, FE (III) ION, Ferric enterobactin receptor, ...
著者Moynie, L, Naismith, J.H.
登録日2018-12-07
公開日2019-01-16
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The complex of ferric-enterobactin with its transporter from Pseudomonas aeruginosa suggests a two-site model.
Nat Commun, 10, 2019
6QGM
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BU of 6qgm by Molmil
VirX1 apo structure
分子名称: VirX1
著者Gkotsi, D.S, Ludewig, H, Sharma, S.V, Unsworth, W.P, Taylor, R.J.K, McLachlan, M.M.W, Shanahan, S, Naismith, J.H, Goss, R.J.M.
登録日2019-01-11
公開日2019-10-30
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献A marine viral halogenase that iodinates diverse substrates.
Nat.Chem., 11, 2019
5JQG
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BU of 5jqg by Molmil
An apo tubulin-RB-TTL complex structure used for side-by-side comparison
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ...
著者Wang, Y.X, Naismith, J.H, Zhu, X.
登録日2016-05-04
公開日2016-05-18
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Pironetin reacts covalently with cysteine-316 of alpha-tubulin to destabilize microtubule
Nat Commun, 7, 2016
5LQ4
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BU of 5lq4 by Molmil
The Structure of ThcOx, the First Oxidase Protein from the Cyanobactin Pathways
分子名称: CyaGox, FLAVIN MONONUCLEOTIDE
著者Bent, A.F, Wagner, A, Naismith, J.H.
登録日2016-08-16
公開日2016-11-09
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structure of the cyanobactin oxidase ThcOx from Cyanothece sp. PCC 7425, the first structure to be solved at Diamond Light Source beamline I23 by means of S-SAD.
Acta Crystallogr D Struct Biol, 72, 2016
5LDV
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BU of 5ldv by Molmil
Crystal Structures of MOMP from Campylobacter jejuni
分子名称: CALCIUM ION, MOMP porin, N-OCTANE, ...
著者Wallat, G.D, Ferrara, L.M.G, Moynie, L, Naismith, J.H.
登録日2016-06-28
公開日2016-10-26
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献MOMP from Campylobacter jejuni Is a Trimer of 18-Stranded beta-Barrel Monomers with a Ca(2+) Ion Bound at the Constriction Zone.
J.Mol.Biol., 428, 2016
4FQ9
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BU of 4fq9 by Molmil
Crystal Structure of 3-hydroxydecanoyl-Acyl Carrier Protein Dehydratase (FabA) from Pseudomonas aeruginosa
分子名称: 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, GLYCEROL, PHOSPHATE ION
著者Moynie, L, Mcmahon, S.A, Duthie, F.G, Naismith, J.H.
登録日2012-06-25
公開日2013-03-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Structural insights into the mechanism and inhibition of the beta-hydroxydecanoyl-acyl carrier protein dehydratase from Pseudomonas aeruginosa
J.Mol.Biol., 425, 2013
5LDT
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BU of 5ldt by Molmil
Crystal Structures of MOMP from Campylobacter jejuni
分子名称: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, CALCIUM ION, MOMP porin
著者Ferrara, L.G.M, Wallat, G.D, Moynie, L, Naismith, J.H.
登録日2016-06-27
公開日2016-10-26
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.88 Å)
主引用文献MOMP from Campylobacter jejuni Is a Trimer of 18-Stranded beta-Barrel Monomers with a Ca(2+) Ion Bound at the Constriction Zone.
J.Mol.Biol., 428, 2016
5M8H
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BU of 5m8h by Molmil
ATP phosphoribosyltransferase (HisZG ATPPRT) from Psychrobacter arcticus
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, ATP phosphoribosyltransferase, ATP phosphoribosyltransferase regulatory subunit, ...
著者Alphey, M.S, Ge, Y, Naismith, J.H, da Silva, R.G.
登録日2016-10-28
公開日2017-09-06
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Kinetics and Structure of a Cold-Adapted Hetero-Octameric ATP Phosphoribosyltransferase.
Biochemistry, 56, 2017
5LMZ
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BU of 5lmz by Molmil
Fluorinase from Streptomyces sp. MA37
分子名称: 1-DEAZA-ADENOSINE, CHLORIDE ION, Fluorinase, ...
著者Mann, G, O'Hagan, D, Naismith, J.H, Bandaranayaka, N.
登録日2016-08-02
公開日2016-08-24
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Identification of fluorinases from Streptomyces sp MA37, Norcardia brasiliensis, and Actinoplanes sp N902-109 by genome mining.
Chembiochem, 15, 2014
5M9B
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BU of 5m9b by Molmil
Crystal structure of the ferric enterobactin receptor (PfeA) from Pseudomonas aeruginosa
分子名称: 1,2-ETHANEDIOL, ACETIC ACID, Ferric enterobactin receptor
著者Moynie, L, Naismith, J.H.
登録日2016-11-01
公開日2018-02-21
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献The complex of ferric-enterobactin with its transporter from Pseudomonas aeruginosa suggests a two-site model.
Nat Commun, 10, 2019
2VA8
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DNA Repair Helicase Hel308
分子名称: SKI2-TYPE HELICASE, SULFATE ION
著者Johnson, K.A, Richards, J, Liu, H, McMahon, S, Oke, M, Carter, L, Naismith, J.H, White, M.F.
登録日2007-08-30
公開日2008-01-15
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of the DNA Repair Helicase Hel308 Reveals DNA Binding and Autoinhibitory Domains.
J.Biol.Chem., 283, 2008
2VHS
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BU of 2vhs by Molmil
Cathsilicatein, a chimera
分子名称: CATHSILICATEIN, SULFATE ION
著者Fairhead, M, Kowatz, T, McMahon, S.A, Carter, L.G, Oke, M, Johnson, K.A, Liu, H, Naismith, J.H, Wal, C.F.V.D.
登録日2007-11-24
公開日2008-03-11
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal Structure and Silica Condensing Activities of Silicatein Alpha-Cathepsin L Chimeras.
Chem. Commun., 2008
7NHR
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BU of 7nhr by Molmil
Putative transmembrane protein Wzc K540M C1
分子名称: Putative transmembrane protein Wzc
著者Liu, J.W, Yang, Y, Naismith, J.H.
登録日2021-02-11
公開日2021-08-25
最終更新日2025-07-02
実験手法ELECTRON MICROSCOPY (2.85 Å)
主引用文献The molecular basis of regulation of bacterial capsule assembly by Wzc.
Nat Commun, 12, 2021

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件を2025-07-09に公開中

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