2V7T

X-ray crystal structure of 5'-fluorodeoxyadenosine synthase s158g mutant complexed with s-adenosyl-l-homocysteine and chloride ion

Summary for 2V7T

Entry DOI	10.2210/pdb2v7t/pdb
Related	1RQP 1RQR 2C2W 2C4T 2C4U 2C5B 2C5H 2CBX 2CC2 2V7U 2V7V 2V7W 2V7X
Descriptor	5'-FLUORO-5'-DEOXYADENOSINE SYNTHASE, S-ADENOSYL-L-HOMOCYSTEINE, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	transferase, mechanism of fluorination, biosynthetic protein
Biological source	STREPTOMYCES CATTLEYA
Total number of polymer chains	3
Total formula weight	98373.99
Authors	Zhu, X.,O'Hagan, D.,Naismith, J.H. (deposition date: 2007-08-01, release date: 2008-08-12, Last modification date: 2023-12-13)
Primary citation	Zhu, X.,Robinson, D.A.,McEwan, A.R.,O'Hagan, D.,Naismith, J.H. Mechanism of enzymatic fluorination in Streptomyces cattleya. J. Am. Chem. Soc., 129:14597-14604, 2007 Cited by PubMed: 17985882 DOI: 10.1021/ja0731569 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.15 Å)

Structure validation