5AV2
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5AUX
| Crystal structure of DAPK1 in complex with kaempferol. | 分子名称: | 3,5,7-TRIHYDROXY-2-(4-HYDROXYPHENYL)-4H-CHROMEN-4-ONE, CHLORIDE ION, Death-associated protein kinase 1 | 著者 | Yokoyama, T, Mizuguchi, M. | 登録日 | 2015-06-10 | 公開日 | 2015-10-07 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural Insight into the Interactions between Death-Associated Protein Kinase 1 and Natural Flavonoids. J.Med.Chem., 58, 2015
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5AUT
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5AV0
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5AUV
| Crystal structure of DAPK1 in complex with apigenin. | 分子名称: | 5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one, CHLORIDE ION, Death-associated protein kinase 1 | 著者 | Yokoyama, T, Mizuguchi, M. | 登録日 | 2015-06-10 | 公開日 | 2015-10-07 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural Insight into the Interactions between Death-Associated Protein Kinase 1 and Natural Flavonoids. J.Med.Chem., 58, 2015
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5AV3
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8WGS
| Crystal structure of V30M-TTR in complex with compound 4 | 分子名称: | Transthyretin, [3,5-bis(iodanyl)-4-oxidanyl-phenyl]-(2-ethyl-4-iodanyl-1-benzofuran-3-yl)methanone | 著者 | Yokoyama, T. | 登録日 | 2023-09-22 | 公開日 | 2024-05-15 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.801 Å) | 主引用文献 | Development of Benziodarone Analogues with Enhanced Potency for Selective Binding to Transthyretin in Human Plasma. J.Med.Chem., 67, 2024
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8WGT
| Crystal structure of V30M-TTR in complex with compound 7 | 分子名称: | Transthyretin, [4,7-bis(chloranyl)-2-ethyl-1-benzofuran-3-yl]-[3,5-bis(iodanyl)-4-oxidanyl-phenyl]methanone | 著者 | Yokoyama, T. | 登録日 | 2023-09-22 | 公開日 | 2024-05-15 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.696 Å) | 主引用文献 | Development of Benziodarone Analogues with Enhanced Potency for Selective Binding to Transthyretin in Human Plasma. J.Med.Chem., 67, 2024
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8WGU
| Crystal structure of V30M-TTR in complex with compound 20 | 分子名称: | Transthyretin, [3,5-bis(iodanyl)-4-oxidanyl-phenyl]-[2-ethyl-4,7-bis(fluoranyl)-1-benzofuran-3-yl]methanone | 著者 | Yokoyama, T. | 登録日 | 2023-09-22 | 公開日 | 2024-05-15 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.508 Å) | 主引用文献 | Development of Benziodarone Analogues with Enhanced Potency for Selective Binding to Transthyretin in Human Plasma. J.Med.Chem., 67, 2024
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8II4
| Crystal structure of V30M-TTR in complex with 6-hydroxy BBM | 分子名称: | Transthyretin, [3,5-bis(bromanyl)-4-oxidanyl-phenyl]-(2-ethyl-6-oxidanyl-1-benzofuran-3-yl)methanone | 著者 | Yokoyama, T. | 登録日 | 2023-02-24 | 公開日 | 2023-06-28 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.499 Å) | 主引用文献 | Benziodarone and 6-hydroxybenziodarone are potent and selective inhibitors of transthyretin amyloidogenesis. Bioorg.Med.Chem., 90, 2023
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8II1
| Crystal structure of V30M-TTR in complex with BID | 分子名称: | Benziodarone, Transthyretin | 著者 | Yokoyama, T. | 登録日 | 2023-02-24 | 公開日 | 2023-06-28 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.907 Å) | 主引用文献 | Benziodarone and 6-hydroxybenziodarone are potent and selective inhibitors of transthyretin amyloidogenesis. Bioorg.Med.Chem., 90, 2023
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8II3
| Crystal structure of V30M-TTR in complex with 6-hydroxy BID | 分子名称: | Transthyretin, [3,5-bis(iodanyl)-4-oxidanyl-phenyl]-(2-ethyl-6-oxidanyl-1-benzofuran-3-yl)methanone | 著者 | Yokoyama, T. | 登録日 | 2023-02-24 | 公開日 | 2023-06-28 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.399 Å) | 主引用文献 | Benziodarone and 6-hydroxybenziodarone are potent and selective inhibitors of transthyretin amyloidogenesis. Bioorg.Med.Chem., 90, 2023
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8II2
| Crystal structure of V30M-TTR in complex with BBM | 分子名称: | CALCIUM ION, Transthyretin, [3,5-bis(bromanyl)-4-oxidanyl-phenyl]-(2-ethyl-1-benzofuran-3-yl)methanone | 著者 | Yokoyama, T. | 登録日 | 2023-02-24 | 公開日 | 2023-06-28 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.798 Å) | 主引用文献 | Benziodarone and 6-hydroxybenziodarone are potent and selective inhibitors of transthyretin amyloidogenesis. Bioorg.Med.Chem., 90, 2023
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8W43
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8W48
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8W47
| X-ray crystal structure of V30M-TTR in complex with isorhapontigenin | 分子名称: | 5-[(~{E})-2-(3-methoxy-4-oxidanyl-phenyl)ethenyl]benzene-1,3-diol, SODIUM ION, Transthyretin | 著者 | Yokoyama, T. | 登録日 | 2023-08-23 | 公開日 | 2023-11-22 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Resveratrol Derivatives Inhibit Transthyretin Fibrillization: Structural Insights into the Interactions between Resveratrol Derivatives and Transthyretin. J.Med.Chem., 66, 2023
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3NG5
| Crystal Structure of V30M transthyretin complexed with (-)-epigallocatechin gallate (EGCG) | 分子名称: | (2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate, GLYCEROL, Transthyretin | 著者 | Miyata, M, Nakamura, T, Ikemizu, S, Chirifu, M, Yamagata, Y, Kai, H. | 登録日 | 2010-06-11 | 公開日 | 2010-07-07 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structure of green tea polyphenol(-)-epigallocatechin gallate (EGCG)-transthyretin complex reveals novel binding site distinct from thyroxine binding site Biochemistry, 2010
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5IX5
| NMR structure of antibacterial factor-2 | 分子名称: | Antibacterial factor-related peptide 2 | 著者 | Masakatsu, K, Umetsu, Y, Rumi, F, Kikukawa, T, Ohki, S, Mizuguchi, M, Demura, M, Aizawa, T. | 登録日 | 2016-03-23 | 公開日 | 2017-03-29 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structure of ABF-2 (antibacterial factor-2) from C. elegans and the interaction with membrane mimetic systems To Be Published
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2Z2E
| Crystal Structure of Canine Milk Lysozyme Stabilized against Non-enzymatic Deamidation | 分子名称: | Lysozyme C, milk isozyme, SULFATE ION | 著者 | Nonaka, Y, Akieda, D, Watanabe, N, Tanaka, I, Kamiya, M, Aizawa, T, Nitta, K, Demura, M, Kawano, K. | 登録日 | 2007-05-21 | 公開日 | 2007-11-27 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Spontaneous asparaginyl deamidation of canine milk lysozyme under mild conditions Proteins, 72, 2008
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8W44
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8W42
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8W45
| X-ray crystal structure of V30M-TTR in complex with pinostilbene | 分子名称: | 3-[(E)-2-(4-hydroxyphenyl)ethenyl]-5-methoxy-phenol, SODIUM ION, Transthyretin | 著者 | Yokoyama, T. | 登録日 | 2023-08-23 | 公開日 | 2023-11-22 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Resveratrol Derivatives Inhibit Transthyretin Fibrillization: Structural Insights into the Interactions between Resveratrol Derivatives and Transthyretin. J.Med.Chem., 66, 2023
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8W46
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1K37
| NMR Structure of human Epiregulin | 分子名称: | Epiregulin | 著者 | Sato, K, Miura, K, Tada, M, Aizawa, T, Miyamoto, K, Kawano, K. | 登録日 | 2001-10-02 | 公開日 | 2003-09-30 | 最終更新日 | 2022-02-23 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of epiregulin and the effect of its C-terminal domain for receptor binding affinity Febs Lett., 553, 2003
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1K36
| NMR Structure of human Epiregulin | 分子名称: | Epiregulin | 著者 | Sato, K, Miura, K, Tada, M, Aizawa, T, Miyamoto, K, Kawano, K. | 登録日 | 2001-10-02 | 公開日 | 2003-09-30 | 最終更新日 | 2022-02-23 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of epiregulin and the effect of its C-terminal domain for receptor binding affinity Febs Lett., 553, 2003
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