8II1

Crystal structure of V30M-TTR in complex with BID

Summary for 8II1

Entry DOI	10.2210/pdb8ii1/pdb
Descriptor	Transthyretin, Benziodarone (3 entities in total)
Functional Keywords	thyroxine, amyloidosis, inhibitor, transport protein
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	35721.33
Authors	Yokoyama, T. (deposition date: 2023-02-24, release date: 2023-06-28, Last modification date: 2023-11-08)
Primary citation	Mizuguchi, M.,Yokoyama, T.,Okada, T.,Nakagawa, Y.,Fujii, K.,Nabeshima, Y.,Toyooka, N. Benziodarone and 6-hydroxybenziodarone are potent and selective inhibitors of transthyretin amyloidogenesis. Bioorg.Med.Chem., 90:117370-117370, 2023 Cited by PubMed: 37311373 DOI: 10.1016/j.bmc.2023.117370 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.907 Å)

Structure validation