1S0H
 
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5KPI
 | | Mouse native PGP | | 分子名称: | Multidrug resistance protein 1A | | 著者 | Xia, D, Esser, L, Zhou, F. | | 登録日 | 2016-07-04 | | 公開日 | 2016-11-30 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (4.01 Å) | | 主引用文献 | Structures of the Multidrug Transporter P-glycoprotein Reveal Asymmetric ATP Binding and the Mechanism of Polyspecificity.
J. Biol. Chem., 292, 2017
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2R98
 | | Crystal Structure of N-acetylglutamate synthase (selenoMet substituted) from Neisseria gonorrhoeae | | 分子名称: | ACETYL COENZYME *A, Putative acetylglutamate synthase | | 著者 | Shi, D, Sagar, V, Jin, Z, Yu, X, Caldovic, L, Morizono, H, Allewell, N.M, Tuchman, M. | | 登録日 | 2007-09-12 | | 公開日 | 2008-01-15 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | The crystal structure of N-acetyl-L-glutamate synthase from Neisseria gonorrhoeae provides insights into mechanisms of catalysis and regulation.
J.Biol.Chem., 283, 2008
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1S19
 | | Crystal structure of VDR ligand binding domain complexed to calcipotriol. | | 分子名称: | CALCIPOTRIOL, Vitamin D3 receptor | | 著者 | Tocchini-Valentini, G, Rochel, N, Wurtz, J.M, Moras, D. | | 登録日 | 2004-01-06 | | 公開日 | 2004-04-13 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structures of the vitamin D nuclear receptor liganded with the vitamin D side chain analogues calcipotriol and seocalcitol, receptor agonists of clinical importance. Insights into a structural basis for the switching of calcipotriol to a receptor antagonist by further side chain modification.
J.Med.Chem., 47, 2004
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1OLT
 | | Coproporphyrinogen III oxidase (HemN) from Escherichia coli is a Radical SAM enzyme. | | 分子名称: | IRON/SULFUR CLUSTER, OXYGEN-INDEPENDENT COPROPORPHYRINOGEN III OXIDASE, S-ADENOSYLMETHIONINE | | 著者 | Layer, G, Moser, J, Heinz, D.W, Jahn, D, Schubert, W.-D. | | 登録日 | 2003-08-13 | | 公開日 | 2003-12-04 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | | 主引用文献 | Crystal Structure of Coproporphyrinogen III Oxidase Reveals Cofactor Geometry of Radical Sam Enzymes
Embo J., 22, 2003
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5KZK
 | | Crystal Structure of rRNA methyltransferase from Sinorhizobium meliloti | | 分子名称: | COBALT (II) ION, Probable RNA methyltransferase, TrmH family, ... | | 著者 | Dey, D, Hegde, R.P, Almo, S.C, Ramakumar, S, Ramagopal, U.A, New York Structural Genomics Research Consortium (NYSGRC) | | 登録日 | 2016-07-25 | | 公開日 | 2017-08-02 | | 最終更新日 | 2019-11-20 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Crystal Structure of rRNA methyltransferase from Sinorhizobium meliloti
To Be Published
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2REJ
 | | ABC-transporter choline binding protein in unliganded semi-closed conformation | | 分子名称: | PUTATIVE GLYCINE BETAINE ABC TRANSPORTER PROTEIN | | 著者 | Oswald, C, Smits, S.H.J, Hoeing, M, Sohn-Boeser, L, Le Rudulier, D, Schmitt, L, Bremer, E. | | 登録日 | 2007-09-26 | | 公開日 | 2008-09-16 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structures of the choline/acetylcholine substrate-binding protein ChoX from Sinorhizobium meliloti in the liganded and unliganded-closed states.
J.Biol.Chem., 283, 2008
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1P37
 | | T4 LYSOZYME CORE REPACKING BACK-REVERTANT L102M/CORE10 | | 分子名称: | 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, LYSOZYME, ... | | 著者 | Mooers, B.H, Datta, D, Baase, W.A, Zollars, E.S, Mayo, S.L, Matthews, B.W. | | 登録日 | 2003-04-16 | | 公開日 | 2003-10-07 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | | 主引用文献 | Repacking the Core of T4 lysozyme by automated design
J.Mol.Biol., 332, 2003
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1S0C
 | | Crystal structure of botulinum neurotoxin type B at pH 5.0 | | 分子名称: | Botulinum neurotoxin type B, CALCIUM ION, ZINC ION | | 著者 | Eswaramoorthy, S, Kumaran, D, Keller, J, Swaminathan, S. | | 登録日 | 2003-12-30 | | 公開日 | 2004-03-16 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Role of metals in the biological activity of Clostridium botulinum neurotoxins
Biochemistry, 43, 2004
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1OKD
 | | NMR-structure of tryparedoxin 1 | | 分子名称: | TRYPAREDOXIN 1 | | 著者 | Krumme, D, Budde, H, Hecht, H.-J, Menge, U, Ohlenschlager, O, Ross, A, Wissing, J, Wray, V, Flohe, L. | | 登録日 | 2003-07-22 | | 公開日 | 2003-08-28 | | 最終更新日 | 2018-01-17 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR studies of the interaction of tryparedoxin with redox-inactive substrate homologues.
Biochemistry, 42, 2003
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1P3N
 | | CORE REDESIGN BACK-REVERTANT I103V/CORE10 | | 分子名称: | 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, LYSOZYME, ... | | 著者 | Mooers, B.H, Datta, D, Baase, W.A, Zollars, E.S, Mayo, S.L, Matthews, B.W. | | 登録日 | 2003-04-17 | | 公開日 | 2003-10-07 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Repacking the Core of T4 lysozyme by automated design
J.Mol.Biol., 332, 2003
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7NLC
 | | Crystallographic structure of human Tsg101 UEV domain in complex with a HEV ORF3 peptide | | 分子名称: | AMMONIUM ION, CHLORIDE ION, Protein ORF3, ... | | 著者 | Moschidi, D, Dupre, E, Villeret, V, Hanoulle, X. | | 登録日 | 2021-02-22 | | 公開日 | 2022-03-02 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.398 Å) | | 主引用文献 | Crystallographic structure of human Tsg101 UEV domain in complex with a HEV ORF3 peptide
To Be Published
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1S2T
 | | Crystal Structure Of Apo Phosphoenolpyruvate Mutase | | 分子名称: | Phosphoenolpyruvate phosphomutase | | 著者 | Liu, S, Lu, Z, Han, Y, Jia, Y, Howard, A, Dunaway-Mariano, D, Herzberg, O. | | 登録日 | 2004-01-11 | | 公開日 | 2004-05-04 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Conformational Flexibility of PEP Mutase
Biochemistry, 43, 2004
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7ND2
 | | Cryo-EM structure of the human FERRY complex | | 分子名称: | Glutamine amidotransferase-like class 1 domain-containing protein 1, Protein phosphatase 1 regulatory subunit 21, Quinone oxidoreductase-like protein 1 | | 著者 | Quentin, D, Klink, B.U, Raunser, S. | | 登録日 | 2021-01-29 | | 公開日 | 2022-03-02 | | 最終更新日 | 2024-07-10 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Structural basis of mRNA binding by the human FERRY Rab5 effector complex.
Mol.Cell, 83, 2023
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1S3M
 | | Structural and Functional Characterization of a Novel Archaeal Phosphodiesterase | | 分子名称: | Hypothetical protein MJ0936, NICKEL (II) ION | | 著者 | Chen, S, Busso, D, Yakunin, A.F, Kuznetsova, E, Proudfoot, M, Jancrick, J, Kim, R, Kim, S.-H, Berkeley Structural Genomics Center (BSGC) | | 登録日 | 2004-01-13 | | 公開日 | 2004-08-10 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural and functional characterization of a novel phosphodiesterase from Methanococcus jannaschii
J.Biol.Chem., 279, 2004
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2RIO
 | | Structure of the dual enzyme Ire1 reveals the basis for catalysis and regulation of non-conventional splicing | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, STRONTIUM ION, ... | | 著者 | Lee, K.P, Dey, M, Neculai, D, Cao, C, Dever, T.E, Sicheri, F. | | 登録日 | 2007-10-12 | | 公開日 | 2008-01-29 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure of the dual enzyme ire1 reveals the basis for catalysis and regulation in nonconventional RNA splicing.
Cell(Cambridge,Mass.), 132, 2008
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2RJB
 | | Crystal structure of uncharacterized protein YdcJ (SF1787) from Shigella flexneri which includes domain DUF1338. Northeast Structural Genomics Consortium target SfR276 | | 分子名称: | Uncharacterized protein, ZINC ION | | 著者 | Seetharaman, J, Chen, Y, Wang, D, Fang, Y, Cunningham, K, Ma, L.-C, Xia, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2007-10-14 | | 公開日 | 2007-10-30 | | 最終更新日 | 2018-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structure of uncharacterized protein YdcJ (SF1787) from Shigella flexneri which includes domain DUF1338.
To be Published
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1S5O
 | | Structural and Mutational Characterization of L-carnitine Binding to Human carnitine Acetyltransferase | | 分子名称: | CARNITINE, carnitine acetyltransferase isoform 2 | | 著者 | Govindasamy, L, Kukar, T, Lian, W, Pedersen, B, Gu, Y, Agbandje-Mckenna, M, Jin, S, Mckenna, R, Wu, D. | | 登録日 | 2004-01-21 | | 公開日 | 2004-02-03 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural and mutational characterization of l-carnitine binding to human carnitine acetyltransferase.
J.Struct.Biol., 146, 2004
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1OUX
 | | LecB (PA-LII) sugar-free | | 分子名称: | CALCIUM ION, SULFATE ION, hypothetical protein LecB | | 著者 | Loris, R, Tielker, D, Jaeger, K.-E, Wyns, L. | | 登録日 | 2003-03-25 | | 公開日 | 2003-09-09 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural Basis of Carbohydrate Recognition by the Lectin LecB from Pseudomonas aeruginosa
J.MOL.BIOL., 331, 2003
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5KNQ
 | | Crystal structure of Mycobacterium tuberculosis hypoxanthine guanine phosphoribosyltransferase in complex with [3S,4R]-(4-(Guanin-9-yl)pyrrolidin-3-yl)oxymethanephosphonic acid and pyrophosphate | | 分子名称: | Hypoxanthine-guanine phosphoribosyltransferase, MAGNESIUM ION, PYROPHOSPHATE 2-, ... | | 著者 | Eng, W.S, Rejman, D, Keough, D.T, Guddat, L.W. | | 登録日 | 2016-06-28 | | 公開日 | 2017-09-20 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.553 Å) | | 主引用文献 | Crystal structure of Mycobacterium tuberculosis hypoxanthine guanine phosphoribosyltransferase in complex with pyrrolidine nucleoside phosphonate
To Be Published
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7NBP
 | | Solution structure of DNA duplex containing a 7,8-dihydro-8-oxo-1,N6-ethenoadenine base modification that induces exclusively A->T transversions in Escherichia coli | | 分子名称: | DNA (5'-D(*CP*AP*TP*GP*AP*GP*TP*AP*C)-3'), DNA (5'-D(*GP*TP*AP*CP*(EDA)P*CP*AP*TP*G)-3') | | 著者 | Aralov, A.V, Gubina, N, Cabrero, C, Tsvetkov, V.B, Turaev, A.V, Fedeles, B.I, Croy, R.G, Isaakova, E.A, Melnik, D, Dukova, S, Khrulev, A.A, Varizhuk, A.M, Gonzalez, C, Zatsepin, T.S, Essigmann, J.M. | | 登録日 | 2021-01-27 | | 公開日 | 2022-03-02 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | 7,8-Dihydro-8-oxo-1,N6-ethenoadenine: an exclusively Hoogsteen-paired thymine mimic in DNA that induces A→T transversions in Escherichia coli.
Nucleic Acids Res., 50, 2022
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5KPK
 | | Glycogen Synthase Kinase 3 beta Complexed with BRD0209 | | 分子名称: | (4~{S})-3-cyclopropyl-4,7,7-trimethyl-4-phenyl-2,6,8,9-tetrahydropyrazolo[3,4-b]quinolin-5-one, Glycogen synthase kinase-3 beta | | 著者 | Lakshminarasimhan, D, White, A, Nadupalli, A, Suto, R.K. | | 登録日 | 2016-07-04 | | 公開日 | 2018-03-14 | | 最終更新日 | 2018-03-21 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Exploiting an Asp-Glu "switch" in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute myeloid leukemia.
Sci Transl Med, 10, 2018
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2REA
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7N17
 | | Structure of TAX-4_R421W apo open state | | 分子名称: | 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Cyclic nucleotide-gated cation channel | | 著者 | Zheng, X, Li, H, Hu, Z, Su, D, Yang, J. | | 登録日 | 2021-05-27 | | 公開日 | 2022-03-16 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural and functional characterization of an achromatopsia-associated mutation in a phototransduction channel.
Commun Biol, 5, 2022
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7N15
 | | Structure of TAX-4_R421W w/cGMP open state | | 分子名称: | 1,2-DILAUROYL-SN-GLYCERO-3-PHOSPHATE, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CYCLIC GUANOSINE MONOPHOSPHATE, ... | | 著者 | Zheng, X, Li, H, Hu, Z, Su, D, Yang, J. | | 登録日 | 2021-05-27 | | 公開日 | 2022-03-16 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structural and functional characterization of an achromatopsia-associated mutation in a phototransduction channel.
Commun Biol, 5, 2022
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