1SOR
 
 | | Aquaporin-0 membrane junctions reveal the structure of a closed water pore | | 分子名称: | Aquaporin-0 | | 著者 | Gonen, T, Sliz, P, Kistler, J, Cheng, Y, Walz, T. | | 登録日 | 2004-03-15 | | 公開日 | 2004-05-11 | | 最終更新日 | 2023-08-23 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (3 Å) | | 主引用文献 | Aquaporin-0 membrane junctions reveal the structure of a closed water pore
Nature, 429, 2004
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2ME3
 | | HIV-1 gp41 clade C Membrane Proximal External Region peptide in DPC micelle | | 分子名称: | Envelope glycoprotein gp160 | | 著者 | Sun, Z.J, Wagner, G, Reinherz, E.L, Kim, M, Song, L, Choi, J, Cheng, Y, Chowdhury, B, Bellot, G, Shih, W. | | 登録日 | 2013-09-20 | | 公開日 | 2013-10-09 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Disruption of Helix-Capping Residues 671 and 674 Reveals a Role in HIV-1 Entry for a Specialized Hinge Segment of the Membrane Proximal External Region of gp41.
J.Mol.Biol., 426, 2014
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2ME2
 | | HIV-1 gp41 clade C Membrane Proximal External Region peptide in DPC micelle | | 分子名称: | Envelope glycoprotein gp160 | | 著者 | Sun, Z.J, Wagner, G, Reinherz, E.L, Kim, M, Song, L, Choi, J, Cheng, Y, Chowdhury, B, Bellot, G, Shih, W. | | 登録日 | 2013-09-20 | | 公開日 | 2013-10-09 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Disruption of Helix-Capping Residues 671 and 674 Reveals a Role in HIV-1 Entry for a Specialized Hinge Segment of the Membrane Proximal External Region of gp41.
J.Mol.Biol., 426, 2014
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6DJP
 | | Integrin alpha-v beta-8 in complex with the Fabs 8B8 and 68 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 68 heavy chain Fab, ... | | 著者 | Cormier, A, Campbell, M.G, Nishimura, S.L, Cheng, Y. | | 登録日 | 2018-05-25 | | 公開日 | 2018-07-25 | | 最終更新日 | 2025-05-14 | | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | | 主引用文献 | Cryo-EM structure of the alpha v beta 8 integrin reveals a mechanism for stabilizing integrin extension.
Nat. Struct. Mol. Biol., 25, 2018
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6E1M
 | | Structure of AtTPC1(DDE) reconstituted in saposin A | | 分子名称: | 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, CALCIUM ION, PALMITIC ACID, ... | | 著者 | Kintzer, A.F, Green, E.M, Cheng, Y, Stroud, R.M. | | 登録日 | 2018-07-10 | | 公開日 | 2018-09-19 | | 最終更新日 | 2024-12-25 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural basis for activation of voltage sensor domains in an ion channel TPC1.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6E1P
 | | Structure of AtTPC1(DDE) in state 2 | | 分子名称: | CALCIUM ION, PALMITIC ACID, Two pore calcium channel protein 1 | | 著者 | Kintzer, A.F, Green, E.M, Cheng, Y, Stroud, R.M. | | 登録日 | 2018-07-10 | | 公開日 | 2018-09-19 | | 最終更新日 | 2024-12-25 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structural basis for activation of voltage sensor domains in an ion channel TPC1.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6BQR
 | | Human TRPM4 ion channel in lipid nanodiscs in a calcium-free state | | 分子名称: | CHOLESTEROL HEMISUCCINATE, Transient receptor potential cation channel subfamily M member 4 | | 著者 | Autzen, H.E, Myasnikov, A.G, Campbell, M.G, Asarnow, D, Julius, D, Cheng, Y. | | 登録日 | 2017-11-28 | | 公開日 | 2017-12-20 | | 最終更新日 | 2024-11-20 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structure of the human TRPM4 ion channel in a lipid nanodisc.
Science, 359, 2018
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6BQV
 | | Human TRPM4 ion channel in lipid nanodiscs in a calcium-bound state | | 分子名称: | CALCIUM ION, CHOLESTEROL HEMISUCCINATE, Transient receptor potential cation channel subfamily M member 4 | | 著者 | Autzen, H.E, Myasnikov, A.G, Campbell, M.G, Asarnow, D, Julius, D, Cheng, Y. | | 登録日 | 2017-11-28 | | 公開日 | 2017-12-20 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structure of the human TRPM4 ion channel in a lipid nanodisc.
Science, 359, 2018
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6E1N
 | | Structure of AtTPC1(DDE) in state 1 | | 分子名称: | 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, CALCIUM ION, PALMITIC ACID, ... | | 著者 | Kintzer, A.F, Green, E.M, Cheng, Y, Stroud, R.M. | | 登録日 | 2018-07-10 | | 公開日 | 2018-09-19 | | 最終更新日 | 2024-12-25 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structural basis for activation of voltage sensor domains in an ion channel TPC1.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6E1K
 | | Structure of AtTPC1(DDE) reconstituted in saposin A with cat06 Fab | | 分子名称: | CALCIUM ION, PALMITIC ACID, Two pore calcium channel protein 1, ... | | 著者 | Kintzer, A.F, Green, E.M, Cheng, Y, Stroud, R.M. | | 登録日 | 2018-07-10 | | 公開日 | 2018-09-19 | | 最終更新日 | 2024-12-25 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural basis for activation of voltage sensor domains in an ion channel TPC1.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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7L2V
 | | cryo-EM structure of RTX-bound minimal TRPV1 with NMDG at state b | | 分子名称: | 6-deoxy-6-(methylamino)-D-galactitol, SODIUM ION, Transient receptor potential cation channel subfamily V member 1, ... | | 著者 | Zhang, K, Julius, D, Cheng, Y. | | 登録日 | 2020-12-17 | | 公開日 | 2021-09-22 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.64 Å) | | 主引用文献 | Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
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7L2N
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7L2O
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7L2L
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7L2T
 | | cryo-EM structure of DkTx-bound minimal TRPV1 in partial open state | | 分子名称: | (2S)-1-(butanoyloxy)-3-{[(R)-hydroxy{[(1r,2R,3S,4S,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propan-2-yl tridecanoate, (9R,12R)-15-amino-12-hydroxy-6,12-dioxo-7,11,13-trioxa-12lambda~5~-phosphapentadecan-9-yl undecanoate, SODIUM ION, ... | | 著者 | Zhang, K, Julius, D, Cheng, Y. | | 登録日 | 2020-12-17 | | 公開日 | 2021-09-22 | | 最終更新日 | 2024-11-20 | | 実験手法 | ELECTRON MICROSCOPY (3.08 Å) | | 主引用文献 | Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
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8SBE
 | | Structure of the rat vesicular glutamate transporter 2 determined by single-particle Cryo-EM | | 分子名称: | Vesicular glutamate transporter 2 | | 著者 | Li, F, Finer-Moore, J, Eriksen, J, Cheng, Y, Edwards, R, Stroud, R. | | 登録日 | 2023-04-03 | | 公開日 | 2023-05-03 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Ion transport and regulation in a synaptic vesicle glutamate transporter.
Science, 368, 2020
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7L2H
 | | Cryo-EM structure of unliganded full-length TRPV1 at neutral pH | | 分子名称: | (10R,13S)-16-amino-13-hydroxy-7,13-dioxo-8,12,14-trioxa-13lambda~5~-phosphahexadecan-10-yl tridecanoate, (2S)-1-(butanoyloxy)-3-{[(R)-hydroxy{[(1r,2R,3S,4S,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propan-2-yl tridecanoate, SODIUM ION, ... | | 著者 | Zhang, K, Julius, D, Cheng, Y. | | 登録日 | 2020-12-17 | | 公開日 | 2021-09-22 | | 最終更新日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (2.63 Å) | | 主引用文献 | Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
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7L2J
 | | Cryo-EM structure of full-length TRPV1 at pH6c state | | 分子名称: | (2S)-1-(butanoyloxy)-3-{[(R)-hydroxy{[(1r,2R,3S,4S,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propan-2-yl tridecanoate, Transient receptor potential cation channel subfamily V member 1 | | 著者 | Zhang, K, Julius, D, Cheng, Y. | | 登録日 | 2020-12-17 | | 公開日 | 2021-09-22 | | 最終更新日 | 2024-11-13 | | 実験手法 | ELECTRON MICROSCOPY (3.66 Å) | | 主引用文献 | Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
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7L2I
 | | Cryo-EM structure of full-length TRPV1 at pH6a state | | 分子名称: | (2S)-1-(butanoyloxy)-3-{[(R)-hydroxy{[(1S,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propan-2-yl tridecanoate, Transient receptor potential cation channel subfamily V member 1 | | 著者 | Zhang, K, Julius, D, Cheng, Y. | | 登録日 | 2020-12-17 | | 公開日 | 2021-09-22 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
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7L2W
 | | cryo-EM structure of RTX-bound minimal TRPV1 with NMDG at state a | | 分子名称: | (10R,13S)-16-amino-13-hydroxy-7,13-dioxo-8,12,14-trioxa-13lambda~5~-phosphahexadecan-10-yl hexadecanoate, SODIUM ION, Transient receptor potential cation channel subfamily V member 1, ... | | 著者 | Zhang, K, Julius, D, Cheng, Y. | | 登録日 | 2020-12-17 | | 公開日 | 2021-09-22 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (3.16 Å) | | 主引用文献 | Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
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7L2S
 | | cryo-EM structure of DkTx-bound minimal TRPV1 at the pre-bound state | | 分子名称: | (10R,13S)-16-amino-13-hydroxy-7,13-dioxo-8,12,14-trioxa-13lambda~5~-phosphahexadecan-10-yl hexadecanoate, (2S)-1-(butanoyloxy)-3-{[(R)-hydroxy{[(1r,2R,3S,4S,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propan-2-yl tridecanoate, SODIUM ION, ... | | 著者 | Zhang, K, Julius, D, Cheng, Y. | | 登録日 | 2020-12-17 | | 公開日 | 2021-09-22 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (2.71 Å) | | 主引用文献 | Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
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7L2K
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7L2U
 | | cryo-EM structure of DkTx-bound minimal TRPV1 in open state | | 分子名称: | (11R,14S)-17-amino-14-hydroxy-8,14-dioxo-9,13,15-trioxa-14lambda~5~-phosphaheptadecan-11-yl decanoate, (2S)-1-(butanoyloxy)-3-{[(R)-hydroxy{[(1r,2R,3S,4S,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propan-2-yl tridecanoate, SODIUM ION, ... | | 著者 | Zhang, K, Julius, D, Cheng, Y. | | 登録日 | 2020-12-17 | | 公開日 | 2021-09-22 | | 最終更新日 | 2024-11-20 | | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | | 主引用文献 | Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
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7L2P
 | | cryo-EM structure of unliganded minimal TRPV1 | | 分子名称: | (10R,13S)-16-amino-13-hydroxy-7,13-dioxo-8,12,14-trioxa-13lambda~5~-phosphahexadecan-10-yl hexadecanoate, (2S)-1-(butanoyloxy)-3-{[(R)-hydroxy{[(1r,2R,3S,4S,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propan-2-yl tridecanoate, SODIUM ION, ... | | 著者 | Zhang, K, Julius, D, Cheng, Y. | | 登録日 | 2020-12-17 | | 公開日 | 2021-09-22 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
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7L2R
 | | Cryo-EM structure of DkTx-bound minimal TRPV1 at the pre-open state | | 分子名称: | (2S)-1-(butanoyloxy)-3-{[(R)-hydroxy{[(1r,2R,3S,4S,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propan-2-yl tridecanoate, (9R,12R)-15-amino-12-hydroxy-6,12-dioxo-7,11,13-trioxa-12lambda~5~-phosphapentadecan-9-yl undecanoate, SODIUM ION, ... | | 著者 | Zhang, K, Julius, D, Cheng, Y. | | 登録日 | 2020-12-17 | | 公開日 | 2021-09-22 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.
Cell, 184, 2021
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