5E1O
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![BU of 5e1o by Molmil](/molmil-images/mine/5e1o) | Crystal structure of NTMT1 in complex with RPKRIA peptide | 分子名称: | GLYCEROL, N-terminal Xaa-Pro-Lys N-methyltransferase 1, RCC1, ... | 著者 | Dong, C, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2015-09-29 | 公開日 | 2015-10-28 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural basis for substrate recognition by the human N-terminal methyltransferase 1. Genes Dev., 29, 2015
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3USH
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![BU of 3ush by Molmil](/molmil-images/mine/3ush) | Crystal Structure of the Q2S0R5 protein from Salinibacter ruber, Northeast Structural Genomics Consortium Target SrR207 | 分子名称: | BROMIDE ION, Uncharacterized protein | 著者 | Vorobiev, S, Su, M, Seetharaman, J, Maglaqui, M, Xiao, R, Kohan, E, Wang, D, Everett, J.K, Acton, T.B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2011-11-23 | 公開日 | 2011-12-14 | 最終更新日 | 2018-06-13 | 実験手法 | X-RAY DIFFRACTION (1.692 Å) | 主引用文献 | Crystal Structure of the Q2S0R5 protein from Salinibacter ruber, Northeast Structural Genomics Consortium Target SrR207 To be Published
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6C1Y
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![BU of 6c1y by Molmil](/molmil-images/mine/6c1y) | mbd of human mecp2 in complex with methylated DNA | 分子名称: | 12-mer DNA, Methyl-CpG-binding protein 2, UNKNOWN ATOM OR ION | 著者 | Liu, K, Bian, C, Tempel, W, Wernimont, A.K, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2018-01-05 | 公開日 | 2018-02-14 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Plasticity at the DNA recognition site of the MeCP2 mCG-binding domain. Biochim Biophys Acta Gene Regul Mech, 1862, 2019
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3B57
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![BU of 3b57 by Molmil](/molmil-images/mine/3b57) | Crystal structure of the Lin1889 protein (Q92AN1) from Listeria innocua. Northeast Structural Consortium target LkR65 | 分子名称: | Lin1889 protein, MAGNESIUM ION | 著者 | Kuzin, A.P, Abashidze, M, Seetharaman, J, Benach, J, Forouhar, F, Vorobiev, S.M, Wang, H, Janjua, H, Cunningham, K, Ma, L.-C, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2007-10-25 | 公開日 | 2007-11-06 | 最終更新日 | 2018-01-24 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal structure of the Lin1889 protein (Q92AN1) from Listeria innocua. To be Published
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6BHD
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![BU of 6bhd by Molmil](/molmil-images/mine/6bhd) | Crystal structure of SETDB1 with a modified H3 peptide | 分子名称: | Histone H3.1, Histone-lysine N-methyltransferase SETDB1, SODIUM ION, ... | 著者 | Qin, S, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2017-10-30 | 公開日 | 2017-12-06 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | H3K14ac is linked to methylation of H3K9 by the triple Tudor domain of SETDB1. Nat Commun, 8, 2017
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6BHH
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![BU of 6bhh by Molmil](/molmil-images/mine/6bhh) | Crystal structure of SETDB1 with a modified H3 peptide | 分子名称: | Histone H3.1, Histone-lysine N-methyltransferase SETDB1, SULFATE ION, ... | 著者 | Qin, S, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2017-10-30 | 公開日 | 2017-11-22 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | H3K14ac is linked to methylation of H3K9 by the triple Tudor domain of SETDB1. Nat Commun, 8, 2017
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6BHE
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![BU of 6bhe by Molmil](/molmil-images/mine/6bhe) | Crystal structure of SETDB1 with a modified H3 peptide | 分子名称: | Histone H3.1, Histone-lysine N-methyltransferase SETDB1, UNKNOWN ATOM OR ION | 著者 | Qin, S, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2017-10-30 | 公開日 | 2017-12-06 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | H3K14ac is linked to methylation of H3K9 by the triple Tudor domain of SETDB1. Nat Commun, 8, 2017
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6BHG
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![BU of 6bhg by Molmil](/molmil-images/mine/6bhg) | Crystal structure of SETDB1 with a modified H3 peptide | 分子名称: | Histone H3.1, Histone-lysine N-methyltransferase SETDB1, UNKNOWN ATOM OR ION | 著者 | Qin, S, Tempel, W, Dong, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2017-10-30 | 公開日 | 2017-12-06 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | H3K14ac is linked to methylation of H3K9 by the triple Tudor domain of SETDB1. Nat Commun, 8, 2017
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6BHI
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![BU of 6bhi by Molmil](/molmil-images/mine/6bhi) | Crystal structure of SETDB1 with a modified H3 peptide | 分子名称: | Histone H3.1, Histone-lysine N-methyltransferase SETDB1, UNKNOWN ATOM OR ION | 著者 | Qin, S, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2017-10-30 | 公開日 | 2017-12-06 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | H3K14ac is linked to methylation of H3K9 by the triple Tudor domain of SETDB1. Nat Commun, 8, 2017
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4Z3C
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![BU of 4z3c by Molmil](/molmil-images/mine/4z3c) | Zinc finger region of human TET3 in complex with CpG DNA | 分子名称: | DNA (5'-D(*GP*CP*CP*AP*AP*CP*GP*TP*TP*GP*GP*C)-3'), Methylcytosine dioxygenase, UNKNOWN ATOM OR ION, ... | 著者 | Liu, K, Xu, C, Tempel, W, Dong, A, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2015-03-31 | 公開日 | 2015-04-29 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | 主引用文献 | DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants. Structure, 2017
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4ZGC
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![BU of 4zgc by Molmil](/molmil-images/mine/4zgc) | Crystal Structure Analysis of Kelch protein (with disulfide bond) from Plasmodium falciparum | 分子名称: | Kelch protein, UNKNOWN ATOM OR ION | 著者 | Jiang, D.Q, Tempel, W, Loppnau, P, Graslund, S, He, H, Ravichandran, M, Seitova, A, Arrowsmith, C.H, Edwards, A.M, Bountra, C, El Bakkouri, M, Senisterra, G, Osman, K.T, Lovato, D.V, Hui, R, Hutchinson, A, Lin, Y.H, Structural Genomics Consortium (SGC) | 登録日 | 2015-04-22 | 公開日 | 2015-06-10 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of kelch protein with disulfide bond from Plasmodium falciparum. to be published
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5KVU
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![BU of 5kvu by Molmil](/molmil-images/mine/5kvu) | |
5E8R
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![BU of 5e8r by Molmil](/molmil-images/mine/5e8r) | Human HMT1 hnRNP methyltransferase-like protein 6 (S. cerevisiae) | 分子名称: | CHLORIDE ION, N-methyl-N-({4-[4-(propan-2-yloxy)phenyl]-1H-pyrrol-3-yl}methyl)ethane-1,2-diamine, Protein arginine N-methyltransferase 6, ... | 著者 | DONG, A, ZENG, H, LIU, J, TEMPEL, W, Seitova, A, Hutchinson, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, JIN, J, BROWN, P.J, WU, H, Structural Genomics Consortium (SGC) | 登録日 | 2015-10-14 | 公開日 | 2015-12-09 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | A Potent, Selective, and Cell-Active Inhibitor of Human Type I Protein Arginine Methyltransferases. Acs Chem.Biol., 11, 2016
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6CVZ
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![BU of 6cvz by Molmil](/molmil-images/mine/6cvz) | Crystal structure of the WD40-repeat of RFWD3 | 分子名称: | E3 ubiquitin-protein ligase RFWD3, MAGNESIUM ION | 著者 | DONG, A, LOPPNAU, P, SEITOVA, A, HUTCHINSON, A, TEMPEL, W, WEI, Y, Bountra, C, Arrowsmith, C.H, Edwards, A.M, BROWN, P.J, TONG, Y, Structural Genomics Consortium (SGC) | 登録日 | 2018-03-29 | 公開日 | 2018-06-27 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Target highlights in CASP13: Experimental target structures through the eyes of their authors. Proteins, 87, 2019
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1SQR
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![BU of 1sqr by Molmil](/molmil-images/mine/1sqr) | Solution Structure of the 50S Ribosomal Protein L35AE from Pyrococcus furiosus. Northeast Structural Genomics Consortium Target PfR48. | 分子名称: | 50S ribosomal protein L35Ae | 著者 | Snyder, D.A, Aramini, J.M, Huang, Y.J, Xiao, R, Cort, J.R, Shastry, R, Ma, L.C, Liu, J, Rost, B, Acton, T.B, Kennedy, M.A, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2004-03-19 | 公開日 | 2004-11-16 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure of the 50S Ribosomal Protein L35AE from Pyrococcus furiosus: Northeast Structural Genomics Consortium Target PfR48 To be Published
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1SQS
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![BU of 1sqs by Molmil](/molmil-images/mine/1sqs) | X-Ray Crystal Structure Protein SP1951 of Streptococcus pneumoniae. Northeast Structural Genomics Consortium Target SpR27. | 分子名称: | L(+)-TARTARIC ACID, conserved hypothetical protein | 著者 | Forouhar, F, Lee, I, Vorobiev, S.M, Xiao, R, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2004-03-19 | 公開日 | 2004-03-30 | 最終更新日 | 2017-12-20 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Functional insights from structural genomics. J.STRUCT.FUNCT.GENOM, 8, 2007
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1SQH
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![BU of 1sqh by Molmil](/molmil-images/mine/1sqh) | X-RAY STRUCTURE OF DROSOPHILA MALONOGASTER PROTEIN Q9VR51 NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET FR87. | 分子名称: | hypothetical protein CG14615-PA | 著者 | Kuzin, A.P, Chen, Y, Forouhar, F, Acton, T.B, Xiao, R, Cooper, B, Ho, C.K, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2004-03-18 | 公開日 | 2004-04-06 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | X-RAY STRUCTURE OF DROSOPHILA MALONOGASTER PROTEIN Q9VR51 NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET FR87 To be Published
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7KBQ
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![BU of 7kbq by Molmil](/molmil-images/mine/7kbq) | |
6AU9
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![BU of 6au9 by Molmil](/molmil-images/mine/6au9) | Crystal structure of Mycobacterium tuberculosis malate synthase in complex with dioxine-phenyldiketoacid | 分子名称: | (2Z)-4-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-hydroxy-4-oxobut-2-enoic acid, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... | 著者 | Krieger, I.V, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2017-08-31 | 公開日 | 2018-09-05 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Anion-pi Interactions in Computer-Aided Drug Design: Modeling the Inhibition of Malate Synthase by Phenyl-Diketo Acids. J Chem Inf Model, 58, 2018
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6APZ
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![BU of 6apz by Molmil](/molmil-images/mine/6apz) | |
6ASU
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![BU of 6asu by Molmil](/molmil-images/mine/6asu) | |
6AS6
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![BU of 6as6 by Molmil](/molmil-images/mine/6as6) | |
6BA7
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![BU of 6ba7 by Molmil](/molmil-images/mine/6ba7) | |
6AXB
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![BU of 6axb by Molmil](/molmil-images/mine/6axb) | |
1SC0
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![BU of 1sc0 by Molmil](/molmil-images/mine/1sc0) | X-ray Structure of YB61_HAEIN Northeast Structural Genomics Consortium Target IR63 | 分子名称: | Hypothetical protein HI1161 | 著者 | Kuzin, A.P, Lee, I, Chiang, Y, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2004-02-11 | 公開日 | 2004-03-30 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | X-ray Structure of YB61_HAEIN Northeast Structural Genomics Consortium Target IR63. To be Published
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