6QFF
 
 | | Crystal Structure of Human Kallikrein 6 in complex with GSK144 | | 分子名称: | 4-[(5-phenyl-1~{H}-imidazol-2-yl)methylamino]-2-(pyridin-3-ylmethoxy)benzenecarboximidamide, GLYCEROL, Kallikrein-6 | | 著者 | Thorpe, J.H. | | 登録日 | 2019-01-10 | | 公開日 | 2019-05-08 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | | 主引用文献 | Evaluation of a crystallographic surrogate for kallikrein 5 in the discovery of novel inhibitors for Netherton syndrome.
Acta Crystallogr.,Sect.F, 75, 2019
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1CLK
 | | CRYSTAL STRUCTURE OF STREPTOMYCES DIASTATICUS NO.7 STRAIN M1033 XYLOSE ISOMERASE AT 1.9 A RESOLUTION WITH PSEUDO-I222 SPACE GROUP | | 分子名称: | COBALT (II) ION, MAGNESIUM ION, XYLOSE ISOMERASE | | 著者 | Niu, L, Teng, M, Zhu, X, Gong, W. | | 登録日 | 1999-04-29 | | 公開日 | 2000-05-03 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure of xylose isomerase from Streptomyces diastaticus no. 7 strain M1033 at 1.85 A resolution.
Acta Crystallogr.,Sect.D, 56, 2000
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7S0J
 | | Crystal structure of Epstein-Barr virus gH/gL targeting antibody 769B10 | | 分子名称: | 769B10 Fab Heavy chain, 769B10 Fab Light chain, GLYCEROL | | 著者 | Chen, W.-H, Kanekiyo, M, Cohen, J.I, Joyce, M.G. | | 登録日 | 2021-08-30 | | 公開日 | 2022-11-09 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Epstein-Barr virus gH/gL has multiple sites of vulnerability for virus neutralization and fusion inhibition.
Immunity, 55, 2022
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7S08
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7S1B
 | | Crystal structure of Epstein-Barr virus glycoproteins gH/gL/gp42-peptide in complex with human neutralizing antibodies 769C2 and 770F7 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 769C2 Fab heavy chain, 769C2 Fab light chain, ... | | 著者 | Chen, W.-H, Cohen, J.I, Kanekiyo, M, Joyce, M.G. | | 登録日 | 2021-09-02 | | 公開日 | 2022-11-09 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.03 Å) | | 主引用文献 | Epstein-Barr virus gH/gL has multiple sites of vulnerability for virus neutralization and fusion inhibition.
Immunity, 55, 2022
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7S07
 | | Crystal structure of Epstein-Barr virus glycoprotein gH/gL/gp42-peptide in complex with human neutralizing antibodies 769B10 and 769C2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 769B10 Fab heavy chain, 769B10 Fab light chain, ... | | 著者 | Chen, W.-H, Kanekiyo, M, Cohen, J.I, Joyce, M.G. | | 登録日 | 2021-08-30 | | 公開日 | 2022-11-09 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.29 Å) | | 主引用文献 | Epstein-Barr virus gH/gL has multiple sites of vulnerability for virus neutralization and fusion inhibition.
Immunity, 55, 2022
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8WHS
 | | Spike Trimer of BA.2.86 in complex with one hACE2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Processed angiotensin-converting enzyme 2, ... | | 著者 | Yue, C, Liu, P. | | 登録日 | 2023-09-23 | | 公開日 | 2024-07-03 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3.33 Å) | | 主引用文献 | Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity.
Natl Sci Rev, 11, 2024
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2YYF
 | | Purification and structural characterization of a D-amino acid containing conopeptide, marmophine, from Conus marmoreus | | 分子名称: | M-conotoxin mr12 | | 著者 | Huang, F, Du, W, Han, Y, Wang, C. | | 登録日 | 2007-04-29 | | 公開日 | 2008-04-08 | | 最終更新日 | 2022-03-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Purification and structural characterization of a D-amino acid-containing conopeptide, conomarphin, from Conus marmoreus.
Febs J., 275, 2008
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1F04
 | | SOLUTION STRUCTURE OF OXIDIZED BOVINE MICROSOMAL CYTOCHROME B5 MUTANT (E44A, E48A, E56A, D60A) AND ITS INTERACTION WITH CYTOCHROME C | | 分子名称: | CYTOCHROME B5, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Wu, Y.B, Lu, J, Qian, C.M, Tang, W.X, Li, E.C, Wang, J.F, Wang, Y.H, Wang, W.H, Lu, J.X, Xie, Y, Huang, Z.X. | | 登録日 | 2000-05-14 | | 公開日 | 2000-06-21 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of cytochrome b(5) mutant (E44/48/56A/D60A) and its interaction with cytochrome c.
Eur.J.Biochem., 268, 2001
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1F03
 | | SOLUTION STRUCTURE OF OXIDIZED BOVINE MICROSOMAL CYTOCHROME B5 MUTANT (E44A, E48A, E56A, D60A) AND ITS INTERACTION WITH CYTOCHROME C | | 分子名称: | CYTOCHROME B5, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Wu, Y.B, Lu, J, Qian, C.M, Tang, W.X, Li, E.C, Wang, J.F, Wang, Y.H, Wang, W.H, Lu, J.X, Xie, Y, Huang, Z.X. | | 登録日 | 2000-05-14 | | 公開日 | 2000-06-21 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of cytochrome b(5) mutant (E44/48/56A/D60A) and its interaction with cytochrome c.
Eur.J.Biochem., 268, 2001
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7YRD
 | | histone methyltransferase | | 分子名称: | DNA (146-MER), Histone H2A.Z, Histone H2B 1.1, ... | | 著者 | Li, H, Wang, W.Y. | | 登録日 | 2022-08-09 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural insight into H4K20 methylation on H2A.Z-nucleosome by SUV420H1.
Mol.Cell, 83, 2023
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7YRG
 | | histone methyltransferase | | 分子名称: | DNA (146-MER), Histone H2A.Z, Histone H2B 1.1, ... | | 著者 | Li, H, Wang, W.Y. | | 登録日 | 2022-08-09 | | 公開日 | 2023-12-13 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Structural insight into H4K20 methylation on H2A.Z-nucleosome by SUV420H1.
Mol.Cell, 83, 2023
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3LYI
 | | PWWP Domain of Human Bromodomain-Containing Protein 1 | | 分子名称: | Bromodomain-containing protein 1, CYSTEINESULFONIC ACID | | 著者 | Lam, R, Zeng, H, Ni, S, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Wu, H, Structural Genomics Consortium (SGC) | | 登録日 | 2010-02-26 | | 公開日 | 2010-03-16 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural and histone binding ability characterizations of human PWWP domains.
Plos One, 6, 2011
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3M0A
 | | Crystal structure of TRAF2:cIAP2 complex | | 分子名称: | Baculoviral IAP repeat-containing protein 3, TNF receptor-associated factor 2, ZINC ION | | 著者 | Kabaleeswaran, V, Wu, H. | | 登録日 | 2010-03-02 | | 公開日 | 2010-04-28 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | | 主引用文献 | Crystal structures of the TRAF2: cIAP2 and the TRAF1: TRAF2: cIAP2 complexes: affinity, specificity, and regulation.
Mol.Cell, 38, 2010
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3M3Z
 | | Crystal structure of HSC70/BAG1 in complex with small molecule inhibitor | | 分子名称: | 5'-O-(2-amino-2-oxoethyl)-8-(methylamino)adenosine, BAG family molecular chaperone regulator 1, Heat shock cognate 71 kDa protein | | 著者 | Dokurno, P, Surgenor, A.E, Shaw, T, Macias, A.T, Massey, A.J, Williamson, D.S. | | 登録日 | 2010-03-10 | | 公開日 | 2011-01-26 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Adenosine-Derived Inhibitors of 78 kDa Glucose Regulated Protein (Grp78) ATPase: Insights into Isoform Selectivity.
J.Med.Chem., 54, 2011
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5NWT
 | | Crystal Structure of Escherichia coli RNA polymerase - Sigma54 Holoenzyme complex | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Zhang, X, Buck, M, Darbari, V.C, Yang, Y, Zhang, N, Lu, D, Glyde, R, Wang, Y, Winkelman, J, Gourse, R.L, Murakami, K.S. | | 登録日 | 2017-05-08 | | 公開日 | 2017-09-13 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (3.76 Å) | | 主引用文献 | TRANSCRIPTION. Structures of the RNA polymerase-Sigma54 reveal new and conserved regulatory strategies.
Science, 349, 2015
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6JIV
 | | SspE crystal structure | | 分子名称: | SspE protein | | 著者 | Bing, Y.Z, Yang, H.G. | | 登録日 | 2019-02-23 | | 公開日 | 2020-03-25 | | 最終更新日 | 2020-07-08 | | 実験手法 | X-RAY DIFFRACTION (3.31 Å) | | 主引用文献 | SspABCD-SspE is a phosphorothioation-sensing bacterial defence system with broad anti-phage activities.
Nat Microbiol, 5, 2020
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5HYX
 | | Plant peptide hormone receptor RGFR1 in complex with RGF1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PTR-SER-ASN-PRO-GLY-HIS-HIS-PRO-HYP-ARG-HIS-ASN, ... | | 著者 | Song, W, Han, Z, Chai, J. | | 登録日 | 2016-02-02 | | 公開日 | 2017-01-11 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.596 Å) | | 主引用文献 | Signature motif-guided identification of receptors for peptide hormones essential for root meristem growth
Cell Res., 26, 2016
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8P2E
 | | Homotypic interacting B1 fab bound to Chondroitin Sulfate A | | 分子名称: | B1 fab heavy, B1 fab light | | 著者 | Raghavan, S.S.R, Dagil, R, Wang, K.T, Salanti, A. | | 登録日 | 2023-05-16 | | 公開日 | 2024-06-05 | | 最終更新日 | 2024-09-11 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Tumor-agnostic cancer therapy using antibodies targeting oncofetal chondroitin sulfate.
Nat Commun, 15, 2024
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6JUF
 | | SspB crystal structure | | 分子名称: | SspB protein | | 著者 | Liqiong, L, Yubing, Z. | | 登録日 | 2019-04-13 | | 公開日 | 2020-03-25 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.587 Å) | | 主引用文献 | SspABCD-SspE is a phosphorothioation-sensing bacterial defence system with broad anti-phage activities.
Nat Microbiol, 5, 2020
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8BRD
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8BRI
 | | VaPomAB MSP1D1 nanodisc | | 分子名称: | Chemotaxis protein PomA, Flagellar motor protein | | 著者 | Hu, H, Taylor, N.M.I. | | 登録日 | 2022-11-23 | | 公開日 | 2023-06-14 | | 最終更新日 | 2023-12-27 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Ion selectivity and rotor coupling of the Vibrio flagellar sodium-driven stator unit.
Nat Commun, 14, 2023
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8SAI
 | | Cryo-EM structure of GPR34-Gi complex | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | | 著者 | Yong, X.H, Zhao, C, Yan, W, Shao, Z.H. | | 登録日 | 2023-04-01 | | 公開日 | 2023-10-04 | | 実験手法 | ELECTRON MICROSCOPY (3.27 Å) | | 主引用文献 | Cryo-EM structures of human GPR34 enable the identification of selective antagonists.
Proc.Natl.Acad.Sci.USA, 120, 2023
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1I5U
 | | SOLUTION STRUCTURE OF CYTOCHROME B5 TRIPLE MUTANT (E48A/E56A/D60A) | | 分子名称: | CYTOCHROME B5, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Qian, C, Yao, Y, Tang, W, Wang, J, Zhongxian, H. | | 登録日 | 2001-02-28 | | 公開日 | 2001-03-21 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Effects of charged amino-acid mutation on the solution structure of cytochrome b(5) and binding between cytochrome b(5) and cytochrome c.
Protein Sci., 10, 2001
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6KE1
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