6EJG
 
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9JSB
 | | guide-bound NbaSPARDA complexes | | 分子名称: | Ago, DREN-APAZ, MAGNESIUM ION, ... | | 著者 | Zhuang, L. | | 登録日 | 2024-09-30 | | 公開日 | 2025-04-02 | | 実験手法 | ELECTRON MICROSCOPY (2.93 Å) | | 主引用文献 | Target DNA-induced filament formation and nuclease activation of SPARDA complex.
Cell Res., 2025
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6E7G
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9JSP
 | | inactive NbaSPARDA complexes | | 分子名称: | Ago, DNA (5'-D(P*GP*CP*TP*GP*TP*GP*CP*AP*GP*TP*AP*TP*T)-3'), DREN-APAZ, ... | | 著者 | Zhuang, L. | | 登録日 | 2024-09-30 | | 公開日 | 2025-04-02 | | 実験手法 | ELECTRON MICROSCOPY (3.34 Å) | | 主引用文献 | Target DNA-induced filament formation and nuclease activation of SPARDA complex.
Cell Res., 2025
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5CL0
 | | 2009 H1N1 PA endonuclease in complex with rUMP | | 分子名称: | MANGANESE (II) ION, Polymerase acidic protein, URIDINE-5'-MONOPHOSPHATE | | 著者 | Kumar, G, White, S.W. | | 登録日 | 2015-07-15 | | 公開日 | 2016-03-16 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | | 主引用文献 | Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor.
Proc.Natl.Acad.Sci.USA, 113, 2016
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9JT2
 | | substrate-bound NbaSPARDA complexes | | 分子名称: | Ago, DNA (5'-D(*TP*AP*TP*CP*GP*TP*CP*AP*GP*CP*TP*GP*TP*GP*CP*AP*GP*TP*AP*TP*T)-3'), DNA (5'-D(P*GP*AP*TP*AP*CP*TP*AP*C)-3'), ... | | 著者 | Zhuang, L. | | 登録日 | 2024-10-01 | | 公開日 | 2025-04-02 | | 実験手法 | ELECTRON MICROSCOPY (3.19 Å) | | 主引用文献 | Target DNA-induced filament formation and nuclease activation of SPARDA complex.
Cell Res., 2025
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9JSZ
 | | active NbaSPARDA complexes | | 分子名称: | Ago, DNA (5'-D(*TP*AP*TP*CP*GP*TP*CP*AP*GP*CP*TP*GP*TP*GP*CP*AP*GP*TP*AP*TP*T)-3'), DREN-APAZ, ... | | 著者 | Zhuang, L. | | 登録日 | 2024-10-01 | | 公開日 | 2025-04-02 | | 実験手法 | ELECTRON MICROSCOPY (3.18 Å) | | 主引用文献 | Target DNA-induced filament formation and nuclease activation of SPARDA complex.
Cell Res., 2025
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5CGV
 | | 2009 H1N1 PA endonuclease in complex with L-742,001 | | 分子名称: | (2Z)-4-[1-benzyl-4-(4-chlorobenzyl)piperidin-4-yl]-2-hydroxy-4-oxobut-2-enoic acid, GLYCEROL, MANGANESE (II) ION, ... | | 著者 | Kumar, G, White, S.W. | | 登録日 | 2015-07-09 | | 公開日 | 2016-03-23 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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6EKH
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6EJM
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6E7I
 | | Human ppGalNAcT2 I253A/L310A Mutant with EA2 and UDP | | 分子名称: | EA2, MANGANESE (II) ION, Polypeptide N-acetylgalactosaminyltransferase 2, ... | | 著者 | Bertozzi, C.R, Schumann, B, Agbay, A.J. | | 登録日 | 2018-07-26 | | 公開日 | 2020-01-29 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Bump-and-Hole Engineering Identifies Specific Substrates of Glycosyltransferases in Living Cells.
Mol.Cell, 78, 2020
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3H91
 | | Crystal structure of the complex of human chromobox homolog 2 (CBX2) and H3K27 peptide | | 分子名称: | Chromobox protein homolog 2, H3K27 peptide | | 著者 | Amaya, M.F, Ravichandran, M, Loppnau, P, Kozieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Bountra, C, Bochkarev, A, Min, J, Ouyang, H, Structural Genomics Consortium (SGC) | | 登録日 | 2009-04-29 | | 公開日 | 2009-08-18 | | 最終更新日 | 2025-03-26 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Recognition and specificity determinants of the human cbx chromodomains.
J.Biol.Chem., 286, 2011
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6EK2
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6EKG
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6K7P
 | | Crystal structure of human AFF4-THD domain | | 分子名称: | AF4/FMR2 family member 4 | | 著者 | Tang, D, Xue, Y, Li, S, Cheng, W, Duan, J, Wang, J, Qi, S. | | 登録日 | 2019-06-08 | | 公開日 | 2020-03-11 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural and functional insight into the effect of AFF4 dimerization on activation of HIV-1 proviral transcription.
Cell Discov, 6, 2020
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5CCU
 | | Crystal structure of endoglycoceramidase I from Rhodococ-cus equi | | 分子名称: | 1,2-ETHANEDIOL, Putative secreted endoglycosylceramidase, SODIUM ION | | 著者 | Chen, L. | | 登録日 | 2015-07-02 | | 公開日 | 2015-09-02 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | | 主引用文献 | Structural Insights into the Broad Substrate Specificity of a Novel Endoglycoceramidase I Belonging to a New Subfamily of GH5 Glycosidases
J. Biol. Chem., 292, 2017
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5D2O
 | | 2009 H1N1 PA endonuclease mutant F105S | | 分子名称: | MANGANESE (II) ION, Polymerase acidic protein | | 著者 | Kumar, G, White, S.W. | | 登録日 | 2015-08-05 | | 公開日 | 2016-03-16 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor.
Proc.Natl.Acad.Sci.USA, 113, 2016
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3JTY
 | | Crystal structure of a BenF-like porin from Pseudomonas fluorescens Pf-5 | | 分子名称: | BenF-like porin, LAURYL DIMETHYLAMINE-N-OXIDE | | 著者 | Sampathkumar, P, Lu, F, Zhao, X, Wasserman, S, Iuzuka, M, Bain, K, Rutter, M, Gheyi, T, Atwell, S, Luz, J, Gilmore, J, Sauder, J.M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2009-09-14 | | 公開日 | 2009-10-20 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | | 主引用文献 | Structure of a putative BenF-like porin from Pseudomonas fluorescens Pf-5 at 2.6 A resolution.
Proteins, 78, 2010
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8FHS
 | | Human L-type voltage-gated calcium channel Cav1.2 in the presence of amiodarone and sofosbuvir at 3.3 Angstrom resolution | | 分子名称: | (2-butyl-1-benzofuran-3-yl){4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl}methanone, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Gao, S, Yao, X, Yan, N. | | 登録日 | 2022-12-15 | | 公開日 | 2023-12-13 | | 最終更新日 | 2025-06-04 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structural basis for human Ca v 1.2 inhibition by multiple drugs and the neurotoxin calciseptine.
Cell, 186, 2023
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6IMC
 | | Crystal Structure of ALKBH1 in complex with Mn(II) and N-Oxalylglycine | | 分子名称: | MANGANESE (II) ION, N-OXALYLGLYCINE, Nucleic acid dioxygenase ALKBH1 | | 著者 | Zhang, M, Yang, S, Zhao, W, Li, H. | | 登録日 | 2018-10-22 | | 公開日 | 2020-01-22 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | Mammalian ALKBH1 serves as an N6-mA demethylase of unpairing DNA.
Cell Res., 30, 2020
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8S9I
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8GUN
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8GUP
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8GUO
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5ZU6
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