6E7I

Human ppGalNAcT2 I253A/L310A Mutant with EA2 and UDP

Summary for 6E7I

• Entry DOI: 10.2210/pdb6e7i/pdb
• Descriptor: Polypeptide N-acetylgalactosaminyltransferase 2, EA2, URIDINE-5'-DIPHOSPHATE, ... (5 entities in total)
• Functional Keywords: glycosyltransferase, glycosylation, bump-hole, galnac, transferase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 62447.64

Authors

Bertozzi, C.R.,Schumann, B.,Agbay, A.J. (deposition date: 2018-07-26, release date: 2020-01-29, Last modification date: 2023-10-11)

• Primary citation: Schumann, B.,Malaker, S.A.,Wisnovsky, S.P.,Debets, M.F.,Agbay, A.J.,Fernandez, D.,Wagner, L.J.S.,Lin, L.,Li, Z.,Choi, J.,Fox, D.M.,Peh, J.,Gray, M.A.,Pedram, K.,Kohler, J.J.,Mrksich, M.,Bertozzi, C.R.; Bump-and-Hole Engineering Identifies Specific Substrates of Glycosyltransferases in Living Cells.; Mol.Cell, 78:824-834.e15, 2020; PubMed: 32325029; DOI: 10.1016/j.molcel.2020.03.030

Experimental method

X-RAY DIFFRACTION (1.8 Å)