3IOP
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![BU of 3iop by Molmil](/molmil-images/mine/3iop) | PDK-1 in complex with the inhibitor Compound-8i | 分子名称: | 2-(5-{[(2R)-2-amino-3-phenylpropyl]oxy}pyridin-3-yl)-8,9-dimethoxybenzo[c][2,7]naphthyridin-4-amine, 3-phosphoinositide-dependent protein kinase 1 | 著者 | Olland, A.M. | 登録日 | 2009-08-14 | 公開日 | 2010-02-16 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The identification of 8,9-dimethoxy-5-(2-aminoalkoxy-pyridin-3-yl)-benzo[c][2,7]naphthyridin-4-ylamines as potent inhibitors of 3-phosphoinositide-dependent kinase-1 (PDK-1). Eur.J.Med.Chem., 45, 2010
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4PVZ
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![BU of 4pvz by Molmil](/molmil-images/mine/4pvz) | Structure of yeast importin a bound to the membrane protein Nuclear Localization Signal sequence of INM protein Heh2 | 分子名称: | Importin subunit alpha, Inner nuclear membrane protein HEH2 | 著者 | Lokareddy, R.K, Hapsari, A.R, van Rheenen, M, Bhardwaj, A, Veenhoff, L.M, Cingolani, C. | 登録日 | 2014-03-18 | 公開日 | 2015-08-26 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Distinctive Properties of the Nuclear Localization Signals of Inner Nuclear Membrane Proteins Heh1 and Heh2. Structure, 23, 2015
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7YOT
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![BU of 7yot by Molmil](/molmil-images/mine/7yot) | |
1O6B
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![BU of 1o6b by Molmil](/molmil-images/mine/1o6b) | |
1O63
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![BU of 1o63 by Molmil](/molmil-images/mine/1o63) | |
1O6C
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![BU of 1o6c by Molmil](/molmil-images/mine/1o6c) | |
2PVU
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![BU of 2pvu by Molmil](/molmil-images/mine/2pvu) | Crystal structures of the arginine-, lysine-, histidine-binding protein ArtJ from the thermophilic bacterium Geobacillus stearothermophilus | 分子名称: | ArtJ, LYSINE, SULFATE ION | 著者 | Vahedi-Faridi, A, Scheffel, F, Eckey, V, Saenger, W, Schneider, E. | 登録日 | 2007-05-10 | 公開日 | 2008-01-15 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Crystal structures and mutational analysis of the arginine-, lysine-, histidine-binding protein ArtJ from Geobacillus stearothermophilus. Implications for interactions of ArtJ with its cognate ATP-binding cassette transporter, Art(MP)2 J.Mol.Biol., 375, 2008
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2Y6V
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![BU of 2y6v by Molmil](/molmil-images/mine/2y6v) | |
6MHG
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![BU of 6mhg by Molmil](/molmil-images/mine/6mhg) | |
3ION
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![BU of 3ion by Molmil](/molmil-images/mine/3ion) | PDK1 in complex with Compound 8h | 分子名称: | 2-(5-{[(2S)-2-amino-3-phenylpropyl]oxy}pyridin-3-yl)-8,9-dimethoxybenzo[c][2,7]naphthyridin-4-amine, 3-phosphoinositide-dependent protein kinase 1, SULFATE ION | 著者 | Olland, A.M. | 登録日 | 2009-08-14 | 公開日 | 2010-02-09 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The identification of 8,9-dimethoxy-5-(2-aminoalkoxy-pyridin-3-yl)-benzo[c][2,7]naphthyridin-4-ylamines as potent inhibitors of 3-phosphoinositide-dependent kinase-1 (PDK-1). Eur.J.Med.Chem., 45, 2010
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1Q53
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1O0H
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![BU of 1o0h by Molmil](/molmil-images/mine/1o0h) | Ribonuclease A in complex with 5'-ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Ribonuclease pancreatic | 著者 | Leonidas, D.D, Oikonomakos, N.G, Chrysina, E.D, Kosmopoulou, M.N, Vlassi, M. | 登録日 | 2003-02-21 | 公開日 | 2003-12-09 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | High-resolution crystal structures of ribonuclease A complexed with adenylic and uridylic nucleotide inhibitors. Implications for structure-based design of ribonucleolytic inhibitors PROTEIN SCI., 12, 2003
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2Z9A
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3C41
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![BU of 3c41 by Molmil](/molmil-images/mine/3c41) | ABC protein ArtP in complex with AMP-PNP/Mg2+ | 分子名称: | Amino acid ABC transporter (ArtP), MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | 著者 | Thaben, P.F, Eckey, V, Scheffel, F, Saenger, W, Schneider, E, Vahedi-Faridi, A. | 登録日 | 2008-01-29 | 公開日 | 2009-02-03 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Crystal Structures of the ATP-binding cassette (ABC) Protein ArtP from Geobacillus stearothermophilus in complexes with nucleotides and nucleotide analogs reveal an intermediate semiclosed dimer in the post hydrolyses state and an asymmetry in the dimerisation region To be Published
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1MDX
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![BU of 1mdx by Molmil](/molmil-images/mine/1mdx) | Crystal structure of ArnB transferase with pyridoxal 5' phosphate | 分子名称: | 2-OXOGLUTARIC ACID, ArnB aminotransferase, GLYCEROL, ... | 著者 | Noland, B.W, Newman, J.M, Hendle, J, Badger, J, Christopher, J.A, Tresser, J, Buchanan, M.D, Wright, T.A, Rutter, M.E, Sanderson, W.E, Muller-Dieckmann, H.-J, Gajiwala, K.S, Sauder, J.M, Buchanan, S.G. | 登録日 | 2002-08-07 | 公開日 | 2002-12-11 | 最終更新日 | 2018-12-26 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Structural studies of Salmonella typhimurium ArnB (PmrH) aminotransferase: A 4-amino-4-deoxy-L-arabinose lipopolysaccharide modifying enzyme Structure, 10, 2002
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2LGC
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2HSG
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![BU of 2hsg by Molmil](/molmil-images/mine/2hsg) | |
1MDO
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![BU of 1mdo by Molmil](/molmil-images/mine/1mdo) | Crystal structure of ArnB aminotransferase with pyridomine 5' phosphate | 分子名称: | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, ArnB aminotransferase | 著者 | Noland, B.W, Newman, J.M, Hendle, J, Badger, J, Christopher, J.A, Tresser, J, Buchanan, M.D, Wright, T, Rutter, M.E, Sanderson, W.E, Muller-Dieckmann, H.-J, Gajiwala, K, Sauder, J.M, Buchanan, S.G. | 登録日 | 2002-08-07 | 公開日 | 2002-12-11 | 最終更新日 | 2018-12-26 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural studies of Salmonella typhimurium ArnB (PmrH) aminotransferase: A 4-amino-4-deoxy-L-arabinose lipopolysaccharide modifying enzyme Structure, 10, 2002
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1MDZ
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![BU of 1mdz by Molmil](/molmil-images/mine/1mdz) | Crystal structure of ArnB aminotransferase with cycloserine and pyridoxal 5' phosphate | 分子名称: | ArnB aminotransferase, D-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-N,O-CYCLOSERYLAMIDE, PYRIDOXAL-5'-PHOSPHATE | 著者 | Noland, B.W, Newman, J.M, Hendle, J, Badger, J, Christopher, J.A, Tresser, J, Buchanan, M.D, Wright, T, Rutter, M.E, Sanderson, W.E, Muller-Dieckmann, H.-J, Gajiwala, K.S, Sauder, J.M, Buchanan, S.G. | 登録日 | 2002-08-07 | 公開日 | 2002-12-11 | 最終更新日 | 2018-12-26 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Structural studies of Salmonella typhimurium ArnB (PmrH) aminotransferase: A 4-amino-4-deoxy-L-arabinose lipopolysaccharide modifying enzyme Structure, 10, 2002
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6KDC
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7Z53
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7YXU
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![BU of 7yxu by Molmil](/molmil-images/mine/7yxu) | Crystal structure of agonistic antibody 1618 fab domain bound to human 4-1BB. | 分子名称: | MANGANESE (II) ION, Tumor necrosis factor receptor superfamily member 9, heavy chain of Fab, ... | 著者 | Hakansson, M, Rose, N, Petersson, J, Enell Smith, K, Thorolfsson, M, von Schantz, L. | 登録日 | 2022-02-16 | 公開日 | 2023-01-25 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | The Bispecific Tumor Antigen-Conditional 4-1BB x 5T4 Agonist, ALG.APV-527, Mediates Strong T-Cell Activation and Potent Antitumor Activity in Preclinical Studies. Mol.Cancer Ther., 22, 2023
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6KDD
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![BU of 6kdd by Molmil](/molmil-images/mine/6kdd) | endoglucanase | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Endoglucanase, GLYCEROL, ... | 著者 | Yu, S, Liuqing, C. | 登録日 | 2019-07-02 | 公開日 | 2020-07-08 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | crystal structure of an endoglucanase from Fervidobacterium pennivorans DSM9078 To Be Published
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2HH0
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2Q2A
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![BU of 2q2a by Molmil](/molmil-images/mine/2q2a) | Crystal structures of the arginine-, lysine-, histidine-binding protein ArtJ from the thermophilic bacterium Geobacillus stearothermophilus | 分子名称: | ARGININE, ArtJ, SULFATE ION | 著者 | Vahedi-Faridi, A, Scheffel, F, Eckey, V, Saenger, W, Schneider, E. | 登録日 | 2007-05-26 | 公開日 | 2008-01-15 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Crystal structures and mutational analysis of the arginine-, lysine-, histidine-binding protein ArtJ from Geobacillus stearothermophilus. Implications for interactions of ArtJ with its cognate ATP-binding cassette transporter, Art(MP)2 J.Mol.Biol., 375, 2008
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