6BYR
 
 | | Structures of the PKA RI alpha holoenzyme with the FLHCC driver J-PKAc alpha or native PKAc alpha | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, DnaJ homolog subfamily B member 1,cAMP-dependent protein kinase catalytic subunit alpha chimera, MAGNESIUM ION, ... | | 著者 | Cao, B, Lu, T.W, Martinez Fiesco, J.A, Tomasini, M, Fan, L, Simon, S.M, Taylor, S.S, Zhang, P. | | 登録日 | 2017-12-21 | | 公開日 | 2019-04-03 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (3.661 Å) | | 主引用文献 | Structures of the PKA RI alpha Holoenzyme with the FLHCC Driver J-PKAc alpha or Wild-Type PKAc alpha.
Structure, 27, 2019
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1X82
 | | CRYSTAL STRUCTURE OF PHOSPHOGLUCOSE ISOMERASE FROM PYROCOCCUS FURIOSUS WITH BOUND 5-phospho-D-arabinonate | | 分子名称: | 5-PHOSPHOARABINONIC ACID, Glucose-6-phosphate isomerase | | 著者 | Berrisford, J.M, Akerboom, J, Brouns, S, Sedelnikova, S.E, Turnbull, A.P, van der Oost, J, Salmon, L, Hardre, R, Murray, I.A, Blackburn, G.M, Rice, D.W, Baker, P.J. | | 登録日 | 2004-08-17 | | 公開日 | 2004-10-12 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | The structures of inhibitor complexes of Pyrococcus furiosus phosphoglucose isomerase provide insights into substrate binding and catalysis.
J.Mol.Biol., 343, 2004
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6BZE
 | | Cryo-EM structure of BCL10 CARD filament | | 分子名称: | B-cell lymphoma/leukemia 10 | | 著者 | David, L, Li, Y, Ma, J, Garner, E, Zhang, X, Wu, H. | | 登録日 | 2017-12-23 | | 公開日 | 2018-02-14 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Assembly mechanism of the CARMA1-BCL10-MALT1-TRAF6 signalosome.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6BI9
 | | Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with 1,2,5-trimethyl-1H-pyrrole-3-carboxylic acid | | 分子名称: | 1,2,5-trimethyl-1H-pyrrole-3-carboxylic acid, DIMETHYL SULFOXIDE, Purine nucleoside phosphorylase | | 著者 | Faheem, M, Neto, J.B, Collins, P, Pearce, N.M, Valadares, N.F, Bird, L, Pereira, H.M, Delft, F.V, Barbosa, J.A.R.G. | | 登録日 | 2017-11-01 | | 公開日 | 2018-11-07 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | | 主引用文献 | Crystal Structure of Purine Nucleoside Phosphorylase Isoform 2 from Schistosoma mansoni in complex with 1,2,5-trimethyl-1H-pyrrole-3-carboxylic acid
To Be Published
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8PN7
 | | Engineered glycolyl-CoA carboxylase (G20R variant) with bound CoA | | 分子名称: | 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, COENZYME A, Propionyl-CoA carboxylase alpha subunit, ... | | 著者 | Zarzycki, J, Marchal, D.G, Schulz, L, Prinz, S, Erb, T.J. | | 登録日 | 2023-06-30 | | 公開日 | 2023-11-29 | | 最終更新日 | 2023-12-27 | | 実験手法 | ELECTRON MICROSCOPY (2.03 Å) | | 主引用文献 | Machine Learning-Supported Enzyme Engineering toward Improved CO 2 -Fixation of Glycolyl-CoA Carboxylase.
Acs Synth Biol, 12, 2023
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1XK3
 | | NADPH- and Ascorbate-Supported Heme Oxygenase Reactions are Distinct. Regiospecificity of Heme Cleavage by the R183E Mutant | | 分子名称: | Heme oxygenase 1, NITRIC OXIDE, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Wang, J, Lad, L, Poulos, T.L, Ortiz de montellano, P.R. | | 登録日 | 2004-09-26 | | 公開日 | 2004-11-09 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | | 主引用文献 | Regiospecificity determinants of human heme oxygenase: differential NADPH- and ascorbate-dependent heme cleavage by the R183E mutant.
J.Biol.Chem., 280, 2005
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6BJF
 | | NMR Structural and biophysical functional analysis of intracellular loop 5 of the NHE1 isoform of the Na+/H+ exchanger. | | 分子名称: | GLY-LEU-THR-TRP-PHE-ILE-ASN-LYS-PHE-ARG-ILE-VAL-LYS | | 著者 | McKay, R, Wong, K, Towle, K, Fliegel, L. | | 登録日 | 2017-11-06 | | 公開日 | 2018-11-14 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Diverse residues of intracellular loop 5 of the Na+/H+exchanger modulate proton sensing, expression, activity and targeting.
Biochim Biophys Acta Biomembr, 1861, 2019
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1X9L
 | | Solution structure of CuI-DR1885 from Deinococcus Radiodurans | | 分子名称: | COPPER (I) ION, CuI-DR1885 | | 著者 | Banci, L, Bertini, I, Ciofi-Baffoni, S, Katsari, E, Katsaros, N, Kubicek, K, Structural Proteomics in Europe (SPINE) | | 登録日 | 2004-08-23 | | 公開日 | 2004-08-31 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A copper(I) protein possibly involved in the assembly of CuA center of bacterial cytochrome c oxidase.
Proc.Natl.Acad.Sci.USA, 102, 2005
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8PFB
 | | Structure of a heteropolymeric type 4 pilus from a monoderm bacterium | | 分子名称: | Type IV pilin PilE1 | | 著者 | Anger, R, Pieulle, L, Shahin, M, Valette, O, Le Guenno, H, Kosta, A, Pelicic, V, Fronzes, R. | | 登録日 | 2023-06-15 | | 公開日 | 2023-11-22 | | 実験手法 | ELECTRON MICROSCOPY (3.67 Å) | | 主引用文献 | Structure of a heteropolymeric type 4 pilus from a monoderm bacterium.
Nat Commun, 14, 2023
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1XB3
 | | The D62C/K74C double mutant of Pseudomonas Aeruginosa Azurin | | 分子名称: | Azurin, COPPER (II) ION | | 著者 | Tigerstrom, A, Schwarz, F, Karlsson, G, Okvist, M, Alvarez-Rua, C, Maeder, D, Robb, F.T, Sjolin, L. | | 登録日 | 2004-08-27 | | 公開日 | 2004-10-19 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.501 Å) | | 主引用文献 | Effects of a novel disulfide bond and engineered electrostatic interactions on the thermostability of azurin
Biochemistry, 43, 2004
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8PM6
 | | Human bile salt export pump (BSEP) in complex with inhibitor GBM in nanodiscs | | 分子名称: | 5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide, Bile salt export pump, CHOLESTEROL | | 著者 | Liu, H, Irobalieva, R.N, Kowal, J, Ni, D, Nosol, K, Bang-Sorensen, R, Lancien, L, Stahlberg, H, Stieger, B, Locher, K.P. | | 登録日 | 2023-06-28 | | 公開日 | 2023-11-22 | | 実験手法 | ELECTRON MICROSCOPY (3.22 Å) | | 主引用文献 | Structural basis of bile salt extrusion and small-molecule inhibition in human BSEP.
Nat Commun, 14, 2023
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1R88
 | | The crystal structure of Mycobacterium tuberculosis MPT51 (FbpC1) | | 分子名称: | MPT51/MPB51 antigen | | 著者 | Wilson, R.A, Maughan, W.N, Kremer, L, Besra, G.S, Futterer, K. | | 登録日 | 2003-10-23 | | 公開日 | 2003-12-30 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | | 主引用文献 | The structure of Mycobacterium tuberculosis MPT51 (FbpC1) defines a new family of non-catalytic alpha/beta hydrolases.
J.Mol.Biol., 335, 2004
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6IBJ
 | | Copper binding protein from Laetisaria arvalis (LaX325) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Auxiliary activity CAZyme, COPPER (II) ION | | 著者 | Frandsen, K.E.H, Tandrup, T, Labourel, A, Haon, M, Berrin, J.-G, Lo Leggio, L. | | 登録日 | 2018-11-30 | | 公開日 | 2019-11-13 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | A fungal family of lytic polysaccharide monooxygenase-like copper proteins.
Nat.Chem.Biol., 16, 2020
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8PKV
 | | Kelch domain of KEAP1 in complex with a ortho-dimethylbenzene linked cyclic peptide 4 (ortho-WRCDEETGEC). | | 分子名称: | (2-methylphenyl)methanol, 1,2-ETHANEDIOL, CHLORIDE ION, ... | | 著者 | Braun, M.B, Bischof, L, Hartmann, M.D. | | 登録日 | 2023-06-27 | | 公開日 | 2023-11-15 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Computational Prediction of Cyclic Peptide Structural Ensembles and Application to the Design of Keap1 Binders.
J.Chem.Inf.Model., 63, 2023
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1RFQ
 | | Actin Crystal Dynamics: Structural Implications for F-actin Nucleation, Polymerization and Branching Mediated by the Anti-parallel Dimer | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ... | | 著者 | Reutzel, R, Yoshioka, C, Govindasamy, L, Yarmola, E.G, Agbandje-McKenna, M, Bubb, M.R, McKenna, R. | | 登録日 | 2003-11-10 | | 公開日 | 2003-12-16 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Actin crystal dynamics: structural implications for F-actin nucleation, polymerization, and branching mediated by the anti-parallel dimer.
J.Struct.Biol., 146, 2004
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1R8L
 | | The structure of endo-beta-1,4-galactanase from Bacillus licheniformis | | 分子名称: | CALCIUM ION, endo-beta-1,4-galactanase | | 著者 | Ryttersgaard, C, Le Nours, J, Lo Leggio, L, Jorgensen, C.T, Christensen, L.L, Bjornvad, M, Larsen, S. | | 登録日 | 2003-10-27 | | 公開日 | 2004-11-02 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The structure of endo-beta-1,4-galactanase from Bacillus licheniformis in complex with two oligosaccharide products
J.Mol.Biol., 341, 2004
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1R9L
 | | structure analysis of ProX in complex with glycine betaine | | 分子名称: | Glycine betaine-binding periplasmic protein, TRIMETHYL GLYCINE, UNKNOWN ATOM OR ION | | 著者 | Schiefner, A, Breed, J, Bosser, L, Kneip, S, Gade, J, Holtmann, G, Diederichs, K, Welte, W, Bremer, E. | | 登録日 | 2003-10-30 | | 公開日 | 2004-02-24 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | | 主引用文献 | Cation-pi Interactions as Determinants for Binding of the Compatible Solutes Glycine Betaine and Proline Betaine by the Periplasmic Ligand-binding Protein ProX from Escherichia coli
J.BIOL.CHEM., 279, 2004
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6C62
 | | An unexpected vestigial protein complex reveals the evolutionary origins of an s-triazine catabolic enzyme. | | 分子名称: | AtzG, Biuret hydrolase, MAGNESIUM ION | | 著者 | Peat, T.S, Esquirol, L, Wilding, M, Liu, J.W, French, N.G, Hartley, C.J, Hideki, O, Easton, C.J, Newman, J, Scott, C. | | 登録日 | 2018-01-17 | | 公開日 | 2018-03-21 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | An unexpected vestigial protein complex reveals the evolutionary origins of ans-triazine catabolic enzyme.
J. Biol. Chem., 293, 2018
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1R9W
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1XN2
 | | New substrate binding pockets for beta-secretase. | | 分子名称: | Beta-secretase 1, OM03-4 | | 著者 | Turner III, R.T, Hong, L, Koelsch, G, Ghosh, A.K, Tang, J. | | 登録日 | 2004-10-04 | | 公開日 | 2005-03-22 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural locations and functional roles of new subsites S5, S6, and S7 in memapsin 2 (beta-secretase).
Biochemistry, 44, 2005
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6C6G
 | | An unexpected vestigial protein complex reveals the evolutionary origins of an s-triazine catabolic enzyme. Inhibitor bound complex. | | 分子名称: | AtzG, Biuret hydrolase, CALCIUM ION | | 著者 | Peat, T.S, Esquirol, L, Wilding, M, Liu, J.W, French, N.G, Hartley, C.J, Hideki, O, Easton, C.J, Newman, J, Scott, C. | | 登録日 | 2018-01-18 | | 公開日 | 2018-03-21 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | An unexpected vestigial protein complex reveals the evolutionary origins of ans-triazine catabolic enzyme.
J. Biol. Chem., 293, 2018
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1XNY
 | | Biotin and propionyl-CoA bound to Acyl-CoA Carboxylase Beta Subunit from S. coelicolor (PccB) | | 分子名称: | BIOTIN, propionyl Coenzyme A, propionyl-CoA carboxylase complex B subunit | | 著者 | Diacovich, L, Mitchell, D.L, Pham, H, Gago, G, Melgar, M.M, Khosla, C, Gramajo, H, Tsai, S.-C. | | 登録日 | 2004-10-05 | | 公開日 | 2004-11-09 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal Structure of the beta-Subunit of Acyl-CoA Carboxylase: Structure-Based Engineering of Substrate Specificity
Biochemistry, 43, 2004
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1XOK
 | | crystal structure of alfalfa mosaic virus RNA 3'UTR in complex with coat protein N terminal peptide | | 分子名称: | BROMIDE ION, Coat protein, alfalfa mosaic virus RNA 3' UTR | | 著者 | Guogas, L.M, Filman, D.J, Hogle, J.M, Gehrke, L. | | 登録日 | 2004-10-06 | | 公開日 | 2005-01-04 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Cofolding organizes alfalfa mosaic virus RNA and coat protein for replication.
Science, 306, 2004
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6C78
 | | Substrate Binding Induces Conformational Changes In A Class A Beta Lactamase That Primes It For Catalysis | | 分子名称: | Beta-lactamase Toho-1 | | 著者 | Langan, P.S, Vandavasi, V.G, Cooper, S.J, Weiss, K.L, Ginell, S.L, Parks, J.M, Coates, L. | | 登録日 | 2018-01-22 | | 公開日 | 2018-03-21 | | 最終更新日 | 2024-03-13 | | 実験手法 | NEUTRON DIFFRACTION (1.75 Å) | | 主引用文献 | Substrate Binding Induces Conformational Changes in a Class A Beta-lactamase That Prime It for Catalysis
Acs Catalysis, 8, 2018
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1RRX
 | | Crystallographic Evidence for Isomeric Chromophores in 3-Fluorotyrosyl-Green Fluorescent Protein | | 分子名称: | SIGF1-GFP fusion protein | | 著者 | Bae, J.H, Paramita Pal, P, Moroder, L, Huber, R, Budisa, N. | | 登録日 | 2003-12-09 | | 公開日 | 2004-06-08 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystallographic Evidence for Isomeric Chromophores in 3-Fluorotyrosyl-Green Fluorescent Protein.
Chembiochem, 5, 2004
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