6C78
Substrate Binding Induces Conformational Changes In A Class A Beta Lactamase That Primes It For Catalysis
Summary for 6C78
| Entry DOI | 10.2210/pdb6c78/pdb |
| Descriptor | Beta-lactamase Toho-1 (2 entities in total) |
| Functional Keywords | hydrolase |
| Biological source | Escherichia coli |
| Total number of polymer chains | 1 |
| Total formula weight | 28045.69 |
| Authors | Langan, P.S.,Vandavasi, V.G.,Cooper, S.J.,Weiss, K.L.,Ginell, S.L.,Parks, J.M.,Coates, L. (deposition date: 2018-01-22, release date: 2018-03-21, Last modification date: 2024-03-13) |
| Primary citation | Langan, P.S.,Vandavasi, V.G.,Cooper, S.J.,Weiss, K.L.,Ginell, S.L.,Parks, J.M.,Coates, L. Substrate Binding Induces Conformational Changes in a Class A Beta-lactamase That Prime It for Catalysis Acs Catalysis, 8:2428-2437, 2018 Cited by DOI: 10.1021/acscatal.7b04114PDB entries with the same primary citation |
| Experimental method | NEUTRON DIFFRACTION (1.75 Å) |
Structure validation
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