8WPV
 
 | | Truncated mutant (1-171) of ferritin from Ureaplasma diversum soaked in Fe2+ solution for 30min | | 分子名称: | CHLORIDE ION, FE (III) ION, MAGNESIUM ION, ... | | 著者 | Wang, W.M, Xi, H.F, Gong, W.J, Ma, D.Y, Wang, H.F. | | 登録日 | 2023-10-10 | | 公開日 | 2024-06-12 | | 実験手法 | X-RAY DIFFRACTION (2.059 Å) | | 主引用文献 | Growth Process of Fe-O Nanoclusters with Different Sizes Biosynthesized by Protein Nanocages.
J.Am.Chem.Soc., 146, 2024
|
|
8WQU
 | | Fe-O nanocluster of form-IX in the 4-fold channel of Ureaplasma diversum ferritin | | 分子名称: | FE (III) ION, ferritin | | 著者 | Wang, W.M, Ma, D.Y, Gong, W.J, Wu, L.J, Wang, H.F. | | 登録日 | 2023-10-12 | | 公開日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Growth Process of Fe-O Nanoclusters with Different Sizes Biosynthesized by Protein Nanocages.
J.Am.Chem.Soc., 146, 2024
|
|
8W6Q
 | | ferritin from Ureaplasma diversum soaking in Fe2+ solution for 0 min | | 分子名称: | CHLORIDE ION, FE (III) ION, Ferritin, ... | | 著者 | Wang, W.M, Xi, H.F, Gong, W.J, Ma, D.Y, Wang, H.F. | | 登録日 | 2023-08-29 | | 公開日 | 2024-06-12 | | 実験手法 | X-RAY DIFFRACTION (2.101 Å) | | 主引用文献 | Growth Process of Fe-O Nanoclusters with Different Sizes Biosynthesized by Protein Nanocages.
J.Am.Chem.Soc., 146, 2024
|
|
8WQX
 | | Fe-O nanocluster of form-X in the 4-fold channel of Ureaplasma diversum ferritin | | 分子名称: | FE (III) ION, ferritin | | 著者 | Wang, W.M, Ma, D.Y, Gong, W.J, Wu, L.J, Wang, H.F. | | 登録日 | 2023-10-12 | | 公開日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Growth Process of Fe-O Nanoclusters with Different Sizes Biosynthesized by Protein Nanocages.
J.Am.Chem.Soc., 146, 2024
|
|
8W6U
 | | Ferritin from Ureaplasma diversum soaking in Fe2+ solution for 5 min | | 分子名称: | CHLORIDE ION, FE (III) ION, Ferritin, ... | | 著者 | Wang, W.M, Xi, H.F, Gong, W.J, Ma, D.Y, Wang, H.F. | | 登録日 | 2023-08-29 | | 公開日 | 2024-06-12 | | 実験手法 | X-RAY DIFFRACTION (2.099 Å) | | 主引用文献 | Growth Process of Fe-O Nanoclusters with Different Sizes Biosynthesized by Protein Nanocages.
J.Am.Chem.Soc., 146, 2024
|
|
6LP6
 | | Crystal structure of human DHODH in complex with inhibitor 1214 | | 分子名称: | 3-[3,5-bis(fluoranyl)-4-[2-fluoranyl-5-(hydroxymethyl)phenyl]phenyl]benzo[f]benzotriazole-4,9-dione, ACETATE ION, Dihydroorotate dehydrogenase (quinone), ... | | 著者 | Chen, Q, Yu, Y. | | 登録日 | 2020-01-09 | | 公開日 | 2020-09-30 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.795 Å) | | 主引用文献 | Bifunctional Naphtho[2,3- d ][1,2,3]triazole-4,9-dione Compounds Exhibit Antitumor Effects In Vitro and In Vivo by Inhibiting Dihydroorotate Dehydrogenase and Inducing Reactive Oxygen Species Production.
J.Med.Chem., 63, 2020
|
|
4KM8
 | | Crystal structure of Sufud60 | | 分子名称: | Suppressor of fused homolog | | 著者 | Zhang, Y, Qi, X, Zhang, Z, Wu, G. | | 登録日 | 2013-05-08 | | 公開日 | 2013-11-20 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | Structural insight into the mutual recognition and regulation between Suppressor of Fused and Gli/Ci.
Nat Commun, 4, 2013
|
|
4KMH
 | |
6KHO
 | | Crystal structure of Oryza sativa TDC with PLP | | 分子名称: | ACETATE ION, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Zhou, Y.Z, Liao, L.J, Liu, X.K, Guo, Y, Zhao, Y.C, Zeng, Z.X. | | 登録日 | 2019-07-16 | | 公開日 | 2020-07-15 | | 実験手法 | X-RAY DIFFRACTION (1.972 Å) | | 主引用文献 | Crystal structure ofOryza sativaTDC reveals the substrate specificity for TDC-mediated melatonin biosynthesis.
J Adv Res, 24, 2020
|
|
6KHN
 | | Crystal structure of Oryza sativa TDC with PLP and SEROTONIN | | 分子名称: | ACETATE ION, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Zhou, Y.Z, Liao, L.J, Liu, X.K, Guo, Y, Zhao, Y.C, Zeng, Z.X. | | 登録日 | 2019-07-16 | | 公開日 | 2020-07-15 | | 実験手法 | X-RAY DIFFRACTION (2.293 Å) | | 主引用文献 | Crystal structure ofOryza sativaTDC reveals the substrate specificity for TDC-mediated melatonin biosynthesis.
J Adv Res, 24, 2020
|
|
3BWN
 | | L-tryptophan aminotransferase | | 分子名称: | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, L-tryptophan aminotransferase, PHENYLALANINE, ... | | 著者 | Ferrer, J.-L, Noel, J.P, Pojer, F, Bowman, M, Chory, J, Tao, Y. | | 登録日 | 2008-01-10 | | 公開日 | 2008-04-29 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Rapid synthesis of auxin via a new tryptophan-dependent pathway is required for shade avoidance in plants
Cell(Cambridge,Mass.), 133, 2008
|
|
4KMD
 | | Crystal structure of Sufud60-Gli1p | | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, GLYCEROL, Sufu, ... | | 著者 | Zhang, Y, Qi, X, Zhang, Z, Wu, G. | | 登録日 | 2013-05-08 | | 公開日 | 2013-11-20 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural insight into the mutual recognition and regulation between Suppressor of Fused and Gli/Ci.
Nat Commun, 4, 2013
|
|
7Z3Z
 | | Locked Wuhan SARS-CoV2 Prefusion Spike ectodomain with lipid bound | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, STEARIC ACID, ... | | 著者 | Duyvesteyn, H.M.E, Carrique, L, Ren, J, Stuart, D.I, Fry, E.E. | | 登録日 | 2022-03-03 | | 公開日 | 2022-05-04 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | The SARS-CoV-2 Spike harbours a lipid binding pocket which modulates stability of the prefusion trimer
bioRxiv, 2020
|
|
7KHL
 | | BRD4-BD1 Compound6 (methyl 4-(3,5-difluoropyridin-2-yl)-10-methyl-7-((methylsulfonyl)methyl)-11-oxo-3,4,10,11-tetrahydro-1H-1,4,10-triazadibenzo[cd,f]azulene-6-carboxylate) | | 分子名称: | Bromodomain-containing protein 4, GLYCEROL, methyl 7-(3,5-difluoropyridin-2-yl)-2-methyl-10-[(methylsulfonyl)methyl]-3-oxo-3,4,6,7-tetrahydro-2H-2,4,7-triazadibenzo[cd,f]azulene-9-carboxylate | | 著者 | Murray, J.M. | | 登録日 | 2020-10-21 | | 公開日 | 2021-02-24 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.286 Å) | | 主引用文献 | Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 2: Improvement of In Vitro Antiproliferation Activity and In Vivo Antitumor Efficacy.
J.Med.Chem., 64, 2021
|
|
7KHH
 | | Ternary complex of VHL/BRD4-BD1/Compound9 (4-(3,5-difluoropyridin-2-yl)-N-(11-(((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-11-oxoundecyl)-10-methyl-7-((methylsulfonyl)methyl)-11-oxo-3,4,10,11-tetrahydro-1H-1,4,10-triazadibenzo[cd,f]azulene-6-carboxamide) | | 分子名称: | Bromodomain-containing protein 4, Elongin-B, Elongin-C, ... | | 著者 | Murray, J.M. | | 登録日 | 2020-10-21 | | 公開日 | 2021-02-24 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.281 Å) | | 主引用文献 | Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 2: Improvement of In Vitro Antiproliferation Activity and In Vivo Antitumor Efficacy.
J.Med.Chem., 64, 2021
|
|
6LZE
 | | The crystal structure of COVID-19 main protease in complex with an inhibitor 11a | | 分子名称: | 3C-like proteinase, DIMETHYL SULFOXIDE, ~{N}-[(2~{S})-3-cyclohexyl-1-oxidanylidene-1-[[(2~{S})-1-oxidanylidene-3-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]propan-2-yl]-1~{H}-indole-2-carboxamide | | 著者 | Zhang, B, Zhang, Y, Jing, Z, Liu, X, Yang, H, Liu, H, Rao, Z, Jiang, H. | | 登録日 | 2020-02-19 | | 公開日 | 2020-04-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.505 Å) | | 主引用文献 | Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease.
Science, 368, 2020
|
|
2WEI
 | | Crystal structure of the kinase domain of Cryptosporidium parvum calcium dependent protein kinase in complex with 3-MB-PP1 | | 分子名称: | 1-tert-butyl-3-(3-methylbenzyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, CALMODULIN-DOMAIN PROTEIN KINASE 1, PUTATIVE | | 著者 | Roos, A.K, King, O, Chaikuad, A, Zhang, C, Shokat, K.M, Wernimont, A.K, Artz, J.D, Lin, L, MacKenzie, F.I, Finerty, P.J, Vedadi, M, Schapira, M, Indarte, M, Kozieradzki, I, Pike, A.C.W, Fedorov, O, Doyle, D, Muniz, J, Arrowsmith, C.H, Weigelt, J, Edwards, A, Bountra, C, von Delft, F, Heightman, T, Hui, R. | | 登録日 | 2009-03-31 | | 公開日 | 2009-04-28 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | The Cryptosporidium Parvum Kinome.
Bmc Genomics, 12, 2011
|
|
5WSH
 | | Structure of HLA-A2 P130 | | 分子名称: | Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, GLY-VAL-TRP-ILE-ARG-THR-PRO-THR-ALA, ... | | 著者 | Zhang, Y, Wu, Y, Qi, J, Liu, J, Gao, G.F, Meng, S. | | 登録日 | 2016-12-07 | | 公開日 | 2017-12-20 | | 最終更新日 | 2019-01-23 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | CD8+T-Cell Response-Associated Evolution of Hepatitis B Virus Core Protein and Disease Progress.
J. Virol., 92, 2018
|
|
6ET4
 | | HUMAN DIHYDROOROTATE DEHYDROGENASE IN COMPLEX WITH NOVEL INHIBITOR | | 分子名称: | (4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID, ACETIC ACID, CHLORIDE ION, ... | | 著者 | Hakansson, M, Walse, B, Gustavsson, A.-L, Lain, S. | | 登録日 | 2017-10-25 | | 公開日 | 2018-03-28 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage.
Nat Commun, 9, 2018
|
|
4M5E
 | | Tse3 structure | | 分子名称: | CADMIUM ION, CALCIUM ION, GLYCEROL, ... | | 著者 | Qian, Y. | | 登録日 | 2013-08-08 | | 公開日 | 2014-04-23 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | | 主引用文献 | Structural insights into the T6SS effector protein Tse3 and the Tse3-Tsi3 complex from Pseudomonas aeruginosa reveal a calcium-dependent membrane-binding mechanism
Mol.Microbiol., 92, 2014
|
|
4GQG
 | | Crystal structure of AKR1B10 complexed with NADP+ | | 分子名称: | Aldo-keto reductase family 1 member B10, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Zhang, L, Zheng, X, Chen, S, Zhai, J, Hu, X. | | 登録日 | 2012-08-23 | | 公開日 | 2013-08-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Inhibitor selectivity between aldo-keto reductase superfamily members AKR1B10 and AKR1B1: Role of Trp112 (Trp111)
Febs Lett., 587, 2013
|
|
4I6L
 | |
5HJC
 | | BRD3 second bromodomain in complex with histone H3 acetylation at K18 | | 分子名称: | 1,2-ETHANEDIOL, Bromodomain-containing protein 3, CHLORIDE ION, ... | | 著者 | Li, Y.Y, Zhao, D, Guan, H.P, Li, H.T. | | 登録日 | 2016-01-13 | | 公開日 | 2016-04-20 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain
Mol.Cell, 62, 2016
|
|
5HJB
 | | AF9 YEATS in complex with histone H3 Crotonylation at K9 | | 分子名称: | Protein AF-9, peptide of Histone H3.1 | | 著者 | Li, Y.Y, Zhao, D, Guan, H.P, Li, H.T. | | 登録日 | 2016-01-12 | | 公開日 | 2016-04-20 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain
Mol.Cell, 62, 2016
|
|
5HJD
 | | AF9 YEATS in complex with histone H3 Crotonylation at K18 | | 分子名称: | COPPER (II) ION, Protein AF-9, SULFATE ION, ... | | 著者 | Li, Y.Y, Zhao, D, Guan, H.P, Li, H.T. | | 登録日 | 2016-01-13 | | 公開日 | 2016-04-20 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.806 Å) | | 主引用文献 | Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain.
Mol.Cell, 62, 2016
|
|
