7JQ2
 
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7JPZ
 | | Structure of the SARS-CoV-2 main protease in complex with inhibitor MPI1 | | 分子名称: | (phenylmethyl) N-[(2S)-1-oxidanylidene-1-[[(2S)-1-oxidanyl-3-[(3S)-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]-3-phenyl-propan-2-yl]carbamate, 3C-like proteinase | | 著者 | Yang, K, Liu, W. | | 登録日 | 2020-08-10 | | 公開日 | 2020-12-23 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | A Quick Route to Multiple Highly Potent SARS-CoV-2 Main Protease Inhibitors*.
Chemmedchem, 16, 2021
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7JQ5
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7JQ3
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7JPY
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7JQ4
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7JQ0
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7JQ1
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5C0Z
 | | The structure of oxidized rat cytochrome c at 1.13 angstroms resolution | | 分子名称: | Cytochrome c, somatic, HEME C, ... | | 著者 | Edwards, B.F.P, Mahapatra, G, Vaishnav, A.A, Brunzelle, J.S, Huttemann, M. | | 登録日 | 2015-06-12 | | 公開日 | 2016-09-21 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.1236 Å) | | 主引用文献 | Serine-47 phosphorylation of cytochromecin the mammalian brain regulates cytochromecoxidase and caspase-3 activity.
Faseb J., 2019
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4HSG
 | | Crystal structure of human PRMT3 in complex with an allosteric inhibitor (PRMT3- KTD) | | 分子名称: | 1-(1,2,3-benzothiadiazol-6-yl)-3-(2-oxo-2-phenylethyl)urea, PRMT3 protein, UNKNOWN ATOM OR ION | | 著者 | Dobrovetsky, E, Dong, A, Liu, F, Li, F, Tempel, W, Siarheyeva, A, Hajian, T, Smil, D, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Brown, P.J, Schapira, M, Jin, J, Vedadi, M, Structural Genomics Consortium (SGC) | | 登録日 | 2012-10-30 | | 公開日 | 2012-12-05 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Exploiting an allosteric binding site of PRMT3 yields potent and selective inhibitors.
J. Med. Chem., 56, 2013
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4M59
 | | Crystal structure of the pentatricopeptide repeat protein PPR10 in complex with an 18-nt psaJ RNA element | | 分子名称: | Chloroplast pentatricopeptide repeat protein 10, PHOSPHATE ION, psaJ RNA | | 著者 | Yin, P, Li, Q, Yan, C, Liu, Y, Yan, N. | | 登録日 | 2013-08-08 | | 公開日 | 2013-10-30 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | | 主引用文献 | Structural basis for the modular recognition of single-stranded RNA by PPR proteins.
Nature, 504, 2013
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5KZY
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5KZZ
 | | Crystal structure of the xenopus Smoothened cysteine-rich domain (CRD) in its apo-form | | 分子名称: | ACETATE ION, GLYCEROL, Smoothened, ... | | 著者 | Huang, P, Kim, Y, Salic, A. | | 登録日 | 2016-07-25 | | 公開日 | 2016-08-17 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.332 Å) | | 主引用文献 | Cellular Cholesterol Directly Activates Smoothened in Hedgehog Signaling.
Cell, 166, 2016
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8JLX
 | | CCHFV envelope protein Gc in complex with Gc13 | | 分子名称: | Glycoprotein C,CCHFV Gc fusion loops, Mouse antibody Gc13 heavy chain, Mouse antibody Gc13 light chain | | 著者 | Chong, T, Cao, S. | | 登録日 | 2023-06-03 | | 公開日 | 2024-01-24 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Neutralizing monoclonal antibodies against the Gc fusion loop region of Crimean-Congo hemorrhagic fever virus.
Plos Pathog., 20, 2024
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8JLW
 | | CCHFV envelope protein Gc in complex with Gc8 | | 分子名称: | Glycoprotein C,CCHFV envelope protein Gc fusion loops, Mouse antibody Gc8 heavy chain, Mouse antibody Gc8 light chain | | 著者 | Chong, T, Cao, S. | | 登録日 | 2023-06-03 | | 公開日 | 2024-01-24 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Neutralizing monoclonal antibodies against the Gc fusion loop region of Crimean-Congo hemorrhagic fever virus.
Plos Pathog., 20, 2024
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8JKD
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8T1U
 | | Crystal structure of the DRM2-CTA DNA complex | | 分子名称: | DNA (5'-D(P*AP*TP*TP*AP*TP*TP*AP*AP*TP*(C49)P*TP*AP*AP*AP*TP*TP*TP*A)-3'), DNA (5'-D(P*TP*AP*AP*AP*TP*TP*TP*AP*GP*AP*TP*TP*AP*AP*TP*AP*AP*T)-3'), DNA (cytosine-5)-methyltransferase DRM2, ... | | 著者 | Chen, J, Lu, J, Song, J. | | 登録日 | 2023-06-03 | | 公開日 | 2023-11-22 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | | 主引用文献 | DNA conformational dynamics in the context-dependent non-CG CHH methylation by plant methyltransferase DRM2.
J.Biol.Chem., 299, 2023
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6ABO
 | | human XRCC4 and IFFO1 complex | | 分子名称: | DNA repair protein XRCC4, GLYCEROL, Intermediate filament family orphan 1, ... | | 著者 | Li, J, Liu, L, Liang, H, Liu, Y, Xu, D. | | 登録日 | 2018-07-23 | | 公開日 | 2019-07-31 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | The nucleoskeleton protein IFFO1 immobilizes broken DNA and suppresses chromosome translocation during tumorigenesis.
Nat.Cell Biol., 21, 2019
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4NNI
 | | Structural basis for targeting the ribosomal protein S1 of Mycobacterium tuberculosis by pyrazinamide | | 分子名称: | 30S ribosomal protein S1, PYRAZINE-2-CARBOXYLIC ACID | | 著者 | Yang, J, Liu, Y, Cai, Q, Lin, D. | | 登録日 | 2013-11-18 | | 公開日 | 2014-12-24 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | | 主引用文献 | Structural basis for targeting the ribosomal protein S1 of Mycobacterium tuberculosis by pyrazinamide.
Mol.Microbiol., 95, 2015
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8SAI
 | | Cryo-EM structure of GPR34-Gi complex | | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | | 著者 | Yong, X.H, Zhao, C, Yan, W, Shao, Z.H. | | 登録日 | 2023-04-01 | | 公開日 | 2023-10-04 | | 実験手法 | ELECTRON MICROSCOPY (3.27 Å) | | 主引用文献 | Cryo-EM structures of human GPR34 enable the identification of selective antagonists.
Proc.Natl.Acad.Sci.USA, 120, 2023
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4NNH
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4NNG
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4NNK
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3PUR
 | | CEKDM7A from C.Elegans, complex with D-2-HG | | 分子名称: | (2R)-2-hydroxypentanedioic acid, FE (II) ION, Lysine-specific demethylase 7 homolog, ... | | 著者 | Yang, Y, Wang, P, Xu, W, Xu, Y. | | 登録日 | 2010-12-06 | | 公開日 | 2011-01-26 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of alpha-ketoglutarate-dependent dioxygenases
Cancer Cell, 19, 2011
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3PUQ
 | | CEKDM7A from C.Elegans, complex with alpha-KG | | 分子名称: | 2-OXOGLUTARIC ACID, FE (II) ION, GLYCEROL, ... | | 著者 | Yang, Y, Wang, P, Xu, W, Xu, Y. | | 登録日 | 2010-12-06 | | 公開日 | 2011-01-26 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of alpha-ketoglutarate-dependent dioxygenases
Cancer Cell, 19, 2011
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