7QN8
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![BU of 7qn8 by Molmil](/molmil-images/mine/7qn8) | Cryo-EM structure of human full-length beta3delta GABA(A)R in complex with histamine and nanobody Nb25 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Gamma-aminobutyric acid receptor subunit beta-3, ... | 著者 | Sente, A, Desai, R, Naydenova, K, Malinauskas, T, Jounaidi, Y, Miehling, J, Zhou, X, Masiulis, S, Hardwick, S.W, Chirgadze, D.Y, Miller, K.W, Aricescu, A.R. | 登録日 | 2021-12-20 | 公開日 | 2022-04-13 | 最終更新日 | 2022-04-20 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Differential assembly diversifies GABA A receptor structures and signalling. Nature, 604, 2022
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7QN6
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![BU of 7qn6 by Molmil](/molmil-images/mine/7qn6) | Cryo-EM structure of human full-length beta3delta GABA(A)R in complex with nanobody Nb25 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | 著者 | Sente, A, Desai, R, Naydenova, K, Malinauskas, T, Jounaidi, Y, Miehling, J, Zhou, X, Masiulis, S, Hardwick, S.W, Chirgadze, D.Y, Miller, K.W, Aricescu, A.R. | 登録日 | 2021-12-20 | 公開日 | 2022-04-13 | 最終更新日 | 2022-04-20 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Differential assembly diversifies GABA A receptor structures and signalling. Nature, 604, 2022
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7QN9
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![BU of 7qn9 by Molmil](/molmil-images/mine/7qn9) | Cryo-EM structure of human full-length extrasynaptic alpha4beta3delta GABA(A)R in complex with GABA, histamine and nanobody Nb25 in a pre-open/closed state | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DECANE, ... | 著者 | Sente, A, Desai, R, Naydenova, K, Malinauskas, T, Jounaidi, Y, Miehling, J, Zhou, X, Masiulis, S, Hardwick, S.W, Chirgadze, D.Y, Miller, K.W, Aricescu, A.R. | 登録日 | 2021-12-20 | 公開日 | 2022-04-13 | 最終更新日 | 2022-04-20 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Differential assembly diversifies GABA A receptor structures and signalling. Nature, 604, 2022
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6LGY
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![BU of 6lgy by Molmil](/molmil-images/mine/6lgy) | Crystal structure of a cysteine-pair mutant (P10C-S291C) of a bacterial bile acid transporter in an inward-facing state complexed with glycine and sodium | 分子名称: | 2,3-dihydroxypropyl (9Z)-octadec-9-enoate, GLYCINE, NONAETHYLENE GLYCOL, ... | 著者 | Wang, X, Lyu, Y, Ji, Y, Sun, Z, Zhou, X. | 登録日 | 2019-12-06 | 公開日 | 2020-12-09 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.247 Å) | 主引用文献 | Substrate binding in the bile acid transporter ASBT Yf from Yersinia frederiksenii. Acta Crystallogr D Struct Biol, 77, 2021
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6LH0
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![BU of 6lh0 by Molmil](/molmil-images/mine/6lh0) | Crystal structure of a cysteine-pair mutant (P10C-S291C) of a bacterial bile acid transporter in an inward-facing apo-state | 分子名称: | 2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Transporter, sodium/bile acid symporter family | 著者 | Wang, X, Lyu, Y, Ji, Y, Sun, Z, Zhou, X. | 登録日 | 2019-12-06 | 公開日 | 2020-12-09 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.812 Å) | 主引用文献 | Substrate binding in the bile acid transporter ASBT Yf from Yersinia frederiksenii. Acta Crystallogr D Struct Biol, 77, 2021
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6LGZ
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![BU of 6lgz by Molmil](/molmil-images/mine/6lgz) | Crystal structure of a cysteine-pair mutant (P10C-S291C) of a bacterial bile acid transporter in an inward-facing state complexed with sulfate | 分子名称: | 2,3-dihydroxypropyl (9Z)-octadec-9-enoate, SULFATE ION, Transporter, ... | 著者 | Wang, X, Lyu, Y, Ji, Y, Sun, Z, Zhou, X. | 登録日 | 2019-12-06 | 公開日 | 2020-12-09 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.428 Å) | 主引用文献 | Substrate binding in the bile acid transporter ASBT Yf from Yersinia frederiksenii. Acta Crystallogr D Struct Biol, 77, 2021
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6LH1
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![BU of 6lh1 by Molmil](/molmil-images/mine/6lh1) | Crystal structure of a cysteine-pair mutant (Y113C-P190C) of a bacterial bile acid transporter trapped in an outward-facing conformation | 分子名称: | 2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CITRIC ACID, Transporter, ... | 著者 | Wang, X, Lyu, Y, Ji, Y, Sun, Z, Zhou, X. | 登録日 | 2019-12-06 | 公開日 | 2020-12-09 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.861 Å) | 主引用文献 | An engineered disulfide bridge traps and validates an outward-facing conformation in a bile acid transporter. Acta Crystallogr D Struct Biol, 77, 2021
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6LGV
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![BU of 6lgv by Molmil](/molmil-images/mine/6lgv) | Crystal structure of a cysteine-pair mutant (P10C-S291C) of a bacterial bile acid transporter in an inward-facing state complexed with citrate | 分子名称: | 2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CITRIC ACID, Transporter, ... | 著者 | Wang, X, Lyu, Y, Ji, Y, Sun, Z, Zhou, X. | 登録日 | 2019-12-06 | 公開日 | 2020-12-09 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.847 Å) | 主引用文献 | Substrate binding in the bile acid transporter ASBT Yf from Yersinia frederiksenii. Acta Crystallogr D Struct Biol, 77, 2021
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5H3O
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![BU of 5h3o by Molmil](/molmil-images/mine/5h3o) | Structure of a eukaryotic cyclic nucleotide-gated channel | 分子名称: | CYCLIC GUANOSINE MONOPHOSPHATE, Cyclic nucleotide-gated cation channel, SODIUM ION | 著者 | Li, M, Zhou, X, Wang, S, Michailidis, I, Gong, Y, Su, D, Li, H, Li, X, Yang, J. | 登録日 | 2016-10-26 | 公開日 | 2017-01-25 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structure of a eukaryotic cyclic-nucleotide-gated channel. Nature, 542, 2017
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7TAK
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![BU of 7tak by Molmil](/molmil-images/mine/7tak) | Structure of a NAT transporter | 分子名称: | GUANINE, Putative membrane protein PurT | 著者 | Weng, J, Zhou, X, Ren, Z, Chen, K, Zhou, M. | 登録日 | 2021-12-21 | 公開日 | 2023-01-25 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.79828 Å) | 主引用文献 | Structure of a NAT transporter To Be Published
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7F5X
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![BU of 7f5x by Molmil](/molmil-images/mine/7f5x) | GK domain of Drosophila P5CS filament with glutamate | 分子名称: | Delta-1-pyrroline-5-carboxylate synthase, GAMMA-L-GLUTAMIC ACID | 著者 | Liu, J.L, Zhong, J, Guo, C.J, Zhou, X. | 登録日 | 2021-06-23 | 公開日 | 2022-04-06 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural basis of dynamic P5CS filaments. Elife, 11, 2022
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7F5V
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![BU of 7f5v by Molmil](/molmil-images/mine/7f5v) | Drosophila P5CS filament with glutamate, ATP, and NADPH | 分子名称: | Delta-1-pyrroline-5-carboxylate synthase | 著者 | Liu, J.L, Zhong, J, Guo, C.J, Zhou, X. | 登録日 | 2021-06-22 | 公開日 | 2022-04-06 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural basis of dynamic P5CS filaments. Elife, 11, 2022
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7F5U
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![BU of 7f5u by Molmil](/molmil-images/mine/7f5u) | |
7F5T
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![BU of 7f5t by Molmil](/molmil-images/mine/7f5t) | Drosophila P5CS filament with glutamate | 分子名称: | Delta-1-pyrroline-5-carboxylate synthase, GLUTAMIC ACID | 著者 | Liu, J.L, Zhong, J, Guo, C.J, Zhou, X. | 登録日 | 2021-06-22 | 公開日 | 2022-05-18 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structural basis of dynamic P5CS filaments. Elife, 11, 2022
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8UYS
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![BU of 8uys by Molmil](/molmil-images/mine/8uys) | SARS-CoV-2 5' proximal stem-loop 5 | 分子名称: | SARS-CoV-2 RNA SL5 domain. | 著者 | Kretsch, R.C, Xu, L, Zheludev, I.N, Zhou, X, Huang, R, Nye, G, Li, S, Zhang, K, Chiu, W, Das, R. | 登録日 | 2023-11-14 | 公開日 | 2023-12-06 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | 主引用文献 | Tertiary folds of the SL5 RNA from the 5' proximal region of SARS-CoV-2 and related coronaviruses. Proc.Natl.Acad.Sci.USA, 121, 2024
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8UYJ
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![BU of 8uyj by Molmil](/molmil-images/mine/8uyj) | BtCoV-HKU5 5' proximal stem-loop 5, conformation 4 | 分子名称: | BtCoV-HKU5 5' proximal stem-loop 5, conformation 4 | 著者 | Kretsch, R.C, Xu, L, Zheludev, I.N, Zhou, X, Huang, R, Nye, G, Li, S, Zhang, K, Chiu, W, Das, R. | 登録日 | 2023-11-13 | 公開日 | 2023-12-06 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (7.3 Å) | 主引用文献 | Tertiary folds of the SL5 RNA from the 5' proximal region of SARS-CoV-2 and related coronaviruses. Proc.Natl.Acad.Sci.USA, 121, 2024
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8UYL
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![BU of 8uyl by Molmil](/molmil-images/mine/8uyl) | MERS 5' proximal stem-loop 5, conformation 2 | 分子名称: | MERS 5' proximal stem-loop 5 | 著者 | Kretsch, R.C, Xu, L, Zheludev, I.N, Zhou, X, Huang, R, Nye, G, Li, S, Zhang, K, Chiu, W, Das, R. | 登録日 | 2023-11-13 | 公開日 | 2023-12-06 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (6.4 Å) | 主引用文献 | Tertiary folds of the SL5 RNA from the 5' proximal region of SARS-CoV-2 and related coronaviruses. Proc.Natl.Acad.Sci.USA, 121, 2024
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8UYK
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![BU of 8uyk by Molmil](/molmil-images/mine/8uyk) | MERS 5' proximal stem-loop 5, conformation 1 | 分子名称: | MERS 5' proximal stem-loop 5 | 著者 | Kretsch, R.C, Xu, L, Zheludev, I.N, Zhou, X, Huang, R, Nye, G, Li, S, Zhang, K, Chiu, W, Das, R. | 登録日 | 2023-11-13 | 公開日 | 2023-12-06 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (6.9 Å) | 主引用文献 | Tertiary folds of the SL5 RNA from the 5' proximal region of SARS-CoV-2 and related coronaviruses. Proc.Natl.Acad.Sci.USA, 121, 2024
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8UYM
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![BU of 8uym by Molmil](/molmil-images/mine/8uym) | MERS 5' proximal stem-loop 5, conformation 3 | 分子名称: | MERS 5' proximal stem-loop 5 | 著者 | Kretsch, R.C, Xu, L, Zheludev, I.N, Zhou, X, Huang, R, Nye, G, Li, S, Zhang, K, Chiu, W, Das, R. | 登録日 | 2023-11-13 | 公開日 | 2023-12-06 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (6.4 Å) | 主引用文献 | Tertiary folds of the SL5 RNA from the 5' proximal region of SARS-CoV-2 and related coronaviruses. Proc.Natl.Acad.Sci.USA, 121, 2024
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8UYG
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![BU of 8uyg by Molmil](/molmil-images/mine/8uyg) | BtCoV-HKU5 5' proximal stem-loop 5, conformation 2 | 分子名称: | RNA (135-MER) | 著者 | Kretsch, R.C, Xu, L, Zheludev, I.N, Zhou, X, Huang, R, Nye, G, Li, S, Zhang, K, Chiu, W, Das, R. | 登録日 | 2023-11-13 | 公開日 | 2023-12-06 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (6.4 Å) | 主引用文献 | Tertiary folds of the SL5 RNA from the 5' proximal region of SARS-CoV-2 and related coronaviruses. Proc.Natl.Acad.Sci.USA, 121, 2024
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8UYE
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![BU of 8uye by Molmil](/molmil-images/mine/8uye) | BtCoV-HKU5 5' proximal stem-loop 5, conformation 1 | 分子名称: | BtCoV-HKU5 5' proximal stem-loop 5 | 著者 | Kretsch, R.C, Xu, L, Zheludev, I.N, Zhou, X, Huang, R, Nye, G, Li, S, Zhang, K, Chiu, W, Das, R. | 登録日 | 2023-11-13 | 公開日 | 2023-12-06 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (5.9 Å) | 主引用文献 | Tertiary folds of the SL5 RNA from the 5' proximal region of SARS-CoV-2 and related coronaviruses. Proc.Natl.Acad.Sci.USA, 121, 2024
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8UYP
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![BU of 8uyp by Molmil](/molmil-images/mine/8uyp) | SARS-CoV-1 5' proximal stem-loop 5 | 分子名称: | SARS-CoV-1 5' proximal stem-loop 5 | 著者 | Kretsch, R.C, Xu, L, Zheludev, I.N, Zhou, X, Huang, R, Nye, G, Li, S, Zhang, K, Chiu, W, Das, R. | 登録日 | 2023-11-13 | 公開日 | 2023-12-20 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (7.1 Å) | 主引用文献 | Tertiary folds of the SL5 RNA from the 5' proximal region of SARS-CoV-2 and related coronaviruses. Proc.Natl.Acad.Sci.USA, 121, 2024
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8GS8
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![BU of 8gs8 by Molmil](/molmil-images/mine/8gs8) | cryo-EM structure of the human respiratory complex II | 分子名称: | (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, ... | 著者 | Du, Z, Zhou, X, Lai, Y, Xu, J, Zhang, Y, Zhou, S, Liu, F, Gao, Y, Gong, H, Rao, Z. | 登録日 | 2022-09-05 | 公開日 | 2023-05-10 | 実験手法 | ELECTRON MICROSCOPY (2.86 Å) | 主引用文献 | Structure of the human respiratory complex II. Proc.Natl.Acad.Sci.USA, 120, 2023
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8JIX
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8JED
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![BU of 8jed by Molmil](/molmil-images/mine/8jed) | Crystal structure of mRNA cap (guanine-N7) methyltransferase E12 subunit from monkeypox virus and discovery of its inhibitors | 分子名称: | mRNA-capping enzyme regulatory subunit OPG124 | 著者 | Wang, D, Zhao, R, Shu, W, Hu, W, Wang, M, Cao, J, Zhou, X. | 登録日 | 2023-05-15 | 公開日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | 主引用文献 | Crystal structure of mRNA cap (guanine-N7) methyltransferase E12 subunit from monkeypox virus and discovery of its inhibitors. Int.J.Biol.Macromol., 253, 2023
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