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4NOO
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BU of 4noo by Molmil
Molecular mechanism for self-protection against type VI secretion system in Vibrio cholerae
分子名称: Putative uncharacterized protein, VgrG protein
著者Yang, X, Xu, M, Jiang, T, Fan, Z.
登録日2013-11-20
公開日2014-04-09
最終更新日2014-04-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Molecular mechanism for self-protection against the type VI secretion system in Vibrio cholerae.
Acta Crystallogr.,Sect.D, 70, 2014
4GDF
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BU of 4gdf by Molmil
A Crystal Structure of SV40 Large T Antigen
分子名称: DNA (32-MER), Large T antigen, ZINC ION
著者Chang, Y.P, Xu, M, Chen, X.S.
登録日2012-07-31
公開日2013-04-10
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Mechanism of Origin DNA Recognition and Assembly of an Initiator-Helicase Complex by SV40 Large Tumor Antigen.
Cell Rep, 3, 2013
5Y61
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BU of 5y61 by Molmil
YfiB-YfiR complexed with GMP
分子名称: GUANOSINE-5'-MONOPHOSPHATE, YfiB, YfiR
著者Zhou, L, Xu, M, Jiang, T.
登録日2017-08-10
公開日2017-09-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献Structural insights into the functional role of GMP in modulating the YfiBNR system
Biochem. Biophys. Res. Commun., 493, 2017
5X3P
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BU of 5x3p by Molmil
Crystal structure of the UBX domain of human UBXD7
分子名称: UBX domain-containing protein 7
著者Jiang, T, Li, Z, Wang, Y, Xu, M.
登録日2017-02-06
公開日2017-03-22
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.999 Å)
主引用文献Crystal structures of the UBX domain of human UBXD7 and its complex with p97 ATPase
Biochem. Biophys. Res. Commun., 486, 2017
5X4L
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BU of 5x4l by Molmil
Crystal structure of the UBX domain of human UBXD7 in complex with p97 N domain
分子名称: Transitional endoplasmic reticulum ATPase, UBX domain-containing protein 7
著者Jiang, T, Li, Z, Wang, Y, Xu, M.
登録日2017-02-13
公開日2017-03-22
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.402 Å)
主引用文献Crystal structures of the UBX domain of human UBXD7 and its complex with p97 ATPase
Biochem. Biophys. Res. Commun., 486, 2017
5Y62
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BU of 5y62 by Molmil
YfiR complexed with GMP
分子名称: GUANOSINE-5'-MONOPHOSPHATE, YfiR
著者Zhou, L, Xu, M, Jiang, T.
登録日2017-08-10
公開日2017-09-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural insights into the functional role of GMP in modulating the YfiBNR system
Biochem. Biophys. Res. Commun., 493, 2017
4TQN
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BU of 4tqn by Molmil
Crystal structure of the bromodomain of human CREBBP in complex with UL04
分子名称: 1,2-ETHANEDIOL, 3-[(5-acetyl-2-ethoxyphenyl)carbamoyl]benzoic acid, CREB-binding protein
著者Dong, J, Caflisch, A.
登録日2014-06-11
公開日2015-06-24
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Discovery of CREBBP Bromodomain Inhibitors by High-Throughput Docking and Hit Optimization Guided by Molecular Dynamics.
J.Med.Chem., 59, 2016
8HEH
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BU of 8heh by Molmil
Crystal structure of GCN5-related N-acetyltransferase 05790
分子名称: COENZYME A, GLYCEROL, GNAT family N-acetyltransferase
著者Xu, M.X, Ran, T.T, Wang, W.
登録日2022-11-08
公開日2022-12-21
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal structure of prodigiosin binding protein PgbP, a GNAT family protein, in Serratia marcescens FS14.
Biochem.Biophys.Res.Commun., 640, 2022
5XGL
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BU of 5xgl by Molmil
Co-crystal structure of Ac-AChBPP in complex with alpha-conotoxin LvIA
分子名称: Alpha-conotoxin LvIA, Soluble acetylcholine receptor
著者Wang, X.Q, Xu, M.Y, Luo, S.L, Zhu, X.P.
登録日2017-04-14
公開日2018-06-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.439 Å)
主引用文献The crystal structure of Ac-AChBP in complex with alpha-conotoxin LvIA reveals the mechanism of its selectivity towards different nAChR subtypes
Protein Cell, 8, 2017
1XJU
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BU of 1xju by Molmil
Crystal structure of secreted inactive form of P1 phage endolysin Lyz
分子名称: Lysozyme, SULFATE ION
著者Arockiasamy, A, Sacchettini, J.C.
登録日2004-09-24
公開日2005-01-11
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.07 Å)
主引用文献Disulfide isomerization after membrane release of its SAR domain activates P1 lysozyme.
Science, 307, 2005
1XJT
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BU of 1xjt by Molmil
Crystal structure of active form of P1 phage endolysin Lyz
分子名称: CITRIC ACID, Lysozyme
著者Arockiasamy, A, Sacchettini, J.C.
登録日2004-09-24
公開日2005-01-11
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Disulfide isomerization after membrane release of its SAR domain activates P1 lysozyme.
Science, 307, 2005
6U3Q
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BU of 6u3q by Molmil
The atomic structure of a human adeno-associated virus capsid isolate (AAVhu69/AAVv66)
分子名称: Capsid protein VP1
著者Hsu, H.-L, Brown, A, Loveland, A, Tai, P, Korostelev, A, Gao, G.
登録日2019-08-22
公開日2020-05-27
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (2.46 Å)
主引用文献Structural characterization of a novel human adeno-associated virus capsid with neurotropic properties.
Nat Commun, 11, 2020
8E4Y
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BU of 8e4y by Molmil
Cryo-EM structure of human glycerol-3-phosphate acyltransferase 1 (GPAT1) in complex with 2-oxohexadecyl-CoA
分子名称: (2R)-2-hydroxy-3-(phosphonooxy)propyl hexadecanoate, Glycerol-3-phosphate acyltransferase 1, mitochondrial, ...
著者Johnson, Z.L, Wasilko, D.J, Ammirati, M, Chang, J.S, Han, S, Wu, H.
登録日2022-08-19
公開日2022-12-21
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis of the acyl-transfer mechanism of human GPAT1.
Nat.Struct.Mol.Biol., 30, 2023
7YJI
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BU of 7yji by Molmil
Crystal structure of Lpg1083 from Legionella pneumophila
分子名称: ACETATE ION, T4SS effector Lpg1083
著者Ge, H, Gao, J, Chen, X.
登録日2022-07-20
公開日2023-06-28
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The bacterial effector SidN/Lpg1083 promotes cell death by targeting Lamin-B2.
J Mol Cell Biol, 15, 2023
9CSG
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BU of 9csg by Molmil
Human Serum Albumin Bound to Cerastecin Compound 5e
分子名称: 2-(4-butylbenzene-1-sulfonamido)-5-(4-{3-carboxy-4-[4-(2-methoxyethyl)benzene-1-sulfonamido]anilino}-4-oxobutanamido)benzoic acid, Albumin, MYRISTIC ACID
著者Hruza, A, Klein, D.J, Ishchenko, A.
登録日2024-07-23
公開日2024-09-04
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.914 Å)
主引用文献Cerastecin Inhibition of the Lipooligosaccharide Transporter MsbA to Combat Acinetobacter baumannii : From Screening Impurity to In Vivo Efficacy.
J.Med.Chem., 67, 2024
7Y50
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BU of 7y50 by Molmil
Class I diterpene synthase (CyS) from Streptomyces cattleya
分子名称: Putative glutamate dehydrogenase/leucine dehydrogenase
著者Xing, B, Ma, M.
登録日2022-06-16
公開日2022-12-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure Based Mutagenesis of Cattleyene Synthase Leads to the Generation of Rearranged Polycyclic Diterpenes.
Angew.Chem.Int.Ed.Engl., 61, 2022
7Y87
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BU of 7y87 by Molmil
class I diterpene synthase mutant (CyS-C59A) from Streptomyces cattleya
分子名称: Putative glutamate dehydrogenase/leucine dehydrogenase
著者Xing, B, Ma, M.
登録日2022-06-23
公開日2022-12-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure Based Mutagenesis of Cattleyene Synthase Leads to the Generation of Rearranged Polycyclic Diterpenes.
Angew.Chem.Int.Ed.Engl., 61, 2022
7Y88
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BU of 7y88 by Molmil
class I diterpene synthase (CyS-GGPP-Mg2+) from Streptomyces cattleya
分子名称: GERANYLGERANYL DIPHOSPHATE, MAGNESIUM ION, Putative glutamate dehydrogenase/leucine dehydrogenase
著者Xing, B, Ma, M.
登録日2022-06-23
公開日2022-12-21
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Crystal Structure Based Mutagenesis of Cattleyene Synthase Leads to the Generation of Rearranged Polycyclic Diterpenes.
Angew.Chem.Int.Ed.Engl., 61, 2022
9CSI
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BU of 9csi by Molmil
A. baumannii MsbA Bound to Cerastecin Compound 5
分子名称: 3,3'-[(1,4-dioxobutane-1,4-diyl)bis(azanediyl)]bis[(4-butylbenzene-1-sulfonamido)benzoic acid], Lipid A export ATP-binding/permease protein MsbA, MAGNESIUM ION, ...
著者Klein, D.J, Ishchenko, A, Soisson, S, Cheng, R, Hennig, M.
登録日2024-07-23
公開日2024-09-04
最終更新日2024-10-02
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Cerastecin Inhibition of the Lipooligosaccharide Transporter MsbA to Combat Acinetobacter baumannii : From Screening Impurity to In Vivo Efficacy.
J.Med.Chem., 67, 2024
6LQN
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BU of 6lqn by Molmil
EBV tegument protein BBRF2
分子名称: Cytoplasmic envelopment protein 1, NITRATE ION, SULFATE ION
著者He, H.P, Luo, M, Cao, Y.L, Gao, S.
登録日2020-01-14
公開日2020-10-07
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.600022 Å)
主引用文献Structure of Epstein-Barr virus tegument protein complex BBRF2-BSRF1 reveals its potential role in viral envelopment.
Nat Commun, 11, 2020
6LQO
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BU of 6lqo by Molmil
EBV tegument protein BBRF2/BSRF1 complex
分子名称: ACETATE ION, Cytoplasmic envelopment protein 1, GLYCEROL, ...
著者He, H.P, Luo, M, Cao, Y.L, Gao, S.
登録日2020-01-14
公開日2020-10-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.0911262 Å)
主引用文献Structure of Epstein-Barr virus tegument protein complex BBRF2-BSRF1 reveals its potential role in viral envelopment.
Nat Commun, 11, 2020
3NUP
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BU of 3nup by Molmil
CDK6 (monomeric) in complex with inhibitor
分子名称: 4-[3-(1-methylethyl)-1H-pyrazol-4-yl]-N-(1-methylpiperidin-4-yl)pyrimidin-2-amine, Cell division protein kinase 6
著者Chopra, R.
登録日2010-07-07
公開日2010-12-22
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献4-(Pyrazol-4-yl)-pyrimidines as selective inhibitors of cyclin-dependent kinase 4/6.
J.Med.Chem., 53, 2010
3NUX
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BU of 3nux by Molmil
CDK6 (monomeric) in complex with inhibitor
分子名称: 4-[5-chloro-3-(1-methylethyl)-1H-pyrazol-4-yl]-N-(5-piperazin-1-ylpyridin-2-yl)pyrimidin-2-amine, Cell division protein kinase 6
著者Chopra, R.
登録日2010-07-07
公開日2010-12-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献4-(Pyrazol-4-yl)-pyrimidines as selective inhibitors of cyclin-dependent kinase 4/6.
J.Med.Chem., 53, 2010
8E50
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BU of 8e50 by Molmil
Cryo-EM structure of human glycerol-3-phosphate acyltransferase 1 (GPAT1) in complex with CoA and palmitoyl-LPA
分子名称: (2R)-2-hydroxy-3-(phosphonooxy)propyl hexadecanoate, COENZYME A, Glycerol-3-phosphate acyltransferase 1, ...
著者Wasilko, D.J, Johnson, Z.L, Ammirati, M, Chang, J.S, Han, S, Wu, H.
登録日2022-08-19
公開日2022-12-21
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.67 Å)
主引用文献Structural basis of the acyl-transfer mechanism of human GPAT1.
Nat.Struct.Mol.Biol., 30, 2023
6XM2
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BU of 6xm2 by Molmil
The structure of the 4A11.v7 antibody in complex with human TGFb2
分子名称: 4A11.v7 heavy chain Fab (VH-CH1) IgG1 humanized, 4A11.v7 kappa light chain Fab (VL-CL) humanized, Transforming growth factor beta-2
著者Lupardus, P.J, Yin, J.P.
登録日2020-06-29
公開日2021-07-07
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献TGF beta 2 and TGF beta 3 isoforms drive fibrotic disease pathogenesis.
Sci Transl Med, 13, 2021

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